中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240721-00281
J Li, Y Dong, F Wang, K H Xu, C Y Wang, L Chen, L N Niu
{"title":"[Exploring the clinical application effects of two different sources of domestic oral restoration membrane in guided bone regeneration during dental implantation in diabetic patients].","authors":"J Li, Y Dong, F Wang, K H Xu, C Y Wang, L Chen, L N Niu","doi":"10.3760/cma.j.cn112144-20240721-00281","DOIUrl":"10.3760/cma.j.cn112144-20240721-00281","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the bone augmentation effects of domestic decellularized porcine small intestinal submucosa (PSIS) absorbable biomembrane and domestic bovine pericardium tissue (BPT) absorbable biomembrane in guided bone regeneration (GBR) for single-tooth implantation in diabetic patients. <b>Methods:</b> A prospective case-control study was conducted with 48 diabetic patients who received single-tooth implant restoration at the Department of Prosthodontics, School of Stomatology. The Fourth Military Medical University, between January 2023 and January 2024. Patients were randomly assigned to the study group (PSIS group) and the control group (BPT group) using a random number table, with 24 patients in each group. GBR was performed simultaneously with the implant surgery. Cone-beam CT was used to compare the buccal-side horizontal bone gain at 6 months post-operation between the two groups. Wound healing was evaluated at 1 and 4 weeks post-operation using wound healing scores. <b>Results:</b> At 6 months post-operation, the buccal-side horizontal bone gain at 2 mm below the implant abutment in the study group [69.1 (55.2, 82.4) mm] and the control group [71.4 (59.8, 77.0) mm] showed no statistically significant difference (<i>Z</i>=-0.25, <i>P</i>=0.805). The wound healing scores at 1 and 4 weeks post-operation in the study group did not differ significantly from those in the control group at the same time points (1 week: <i>Z</i>=-0.49, <i>P</i>=0.627; 4 weeks: <i>Z</i>=-0.61, <i>P</i>=0.539). <b>Conclusions:</b> The use of two types of domestic absorbable collagen membranes for GBR in single-tooth implantation in diabetic patients showed comparable buccal-side horizontal bone gain effects at 6 months post-operation and similar clinical outcomes for wound healing at 1 and 4 weeks post-operation in both groups. The GBR effects of PSIS and BPT are similar.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"116-122"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240221-00081
X Wang
{"title":"[Geostatics in impacted mandibular third molar surgury].","authors":"X Wang","doi":"10.3760/cma.j.cn112144-20240221-00081","DOIUrl":"10.3760/cma.j.cn112144-20240221-00081","url":null,"abstract":"<p><p>Exploring the application of minimally invasive techniques in the extraction of impacted mandibular third molar (IMTM), to achieve the treatment goal of \"less trauma, short time, fast recovery\", remains the focus of dentists. For now, the IMTM are mostly extracted in pieces after removing the crown and root resistance by bone removal and tooth segmentation, using 45°reverse-angle high speed turbine, piezosurgery, chisel or other dynamic system. However, There is a lack of principle-level parsing in different provinces and primary hospitals, while experience is still the main factor in avoiding excessive bone removal in complex IMTM extraction, as well as optimizing the specific position and angle of the parting teeth, finding the fulcrum and designing the best dislocation path when there is root resistance. In this review, the principle of geostatics was introduced into the extraction of IMTM. According to this principle, we analyzed how to design a clever tooth cutting line cleverly to enhance the efficiency of tooth segmentation, and how to optimize the mechanical design of root dislocation and the root dislocation path. Meanwhile, we will also focus on how to minimize trauma to alveolar bone during tooth extraction, so as to reduce the risk of intraoperative and postoperative complications, and provide interpretation and reference for dentists in surgical design and techniques of minimally invasive tooth extraction.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"109-115"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20241021-00391
H Chen, H Zhang, X C Zhao, L He
{"title":"[Effect of concentrated growth factor on the biological performance of human dental pulp stem cells under oxidative stress status].","authors":"H Chen, H Zhang, X C Zhao, L He","doi":"10.3760/cma.j.cn112144-20241021-00391","DOIUrl":"10.3760/cma.j.cn112144-20241021-00391","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the effect of concentrated growth factor (CGF) on the biological performance of human dental pulp stem cells (hDPSCs) under oxidative stress status induced by hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>). <b>Methods:</b> The hDPSCs were isolated by using tissue block separation method from healthy permanent teeth extracted for orthodontic reason. hDPSCs surface markers CD34, CD45, CD90 and CD105 were detected by flow cytometry. Alkaline phosphatase (ALP), alizarin red S (ARS), oil red O staining and colony formation assay were used to identify hDPSCs. After the cell counting kit-8 (CCK-8) detection, the optimal H<sub>2</sub>O<sub>2</sub> concentration was used to construct the hDPSCs oxidative stress model. CGF conditioned medium was prepared by repeated freeze-thaw methods. After CCK-8 detection, the optimum CGF concentration was chosen for the subsequent experiments. The hDPSCs were divided into control group, H<sub>2</sub>O<sub>2</sub> (only H<sub>2</sub>O<sub>2</sub> processing), H<sub>2</sub>O<sub>2</sub>+CGF group (H<sub>2</sub>O<sub>2</sub> processing in combination with the CGF) and CGF group (only CGF processing). Subsequent experiments were performed according to these groups. The oxidative stress model was verified by reactive oxygen species, β-galactosidase staining and Western blotting. The effects of CGF on the proliferation and migration of hDPSCs under oxidative stress status were detected by CCK-8 and cell scratch assay, respectively. ALP activity and ARS staining were used to detect the effect of CGF on the osteogenic differentiation of hDPSCs under oxidative stress status. The mRNA expression levels of odontogenesis related genes were detected by real-time fluorescence quantitative PCR (RT-qPCR), and the expression levels of odontogenesis and osteogenesis related proteins were detected by Western blotting. <b>Results:</b> Isolated hDPSCs showed positive expression of mesenchymal stem cells surface markers of CD90, CD105, and negative expression of hematopoietic stem cells surface markers CD34, CD45. The hDPSCs were proved to have the capacity of osteogenic, adipogenic differentiation and clone formation. The optimal concentration to construct the oxidative stress model was 200 μmol/L H<sub>2</sub>O<sub>2</sub>. Twenty percent CGF was the optimal concentration for subsequent experiments. Compared with the control group, the expression of aging protein p53 was significantly up-regulated from (0.82±0.12) to (1.19±0.14) in H<sub>2</sub>O<sub>2</sub> group (<i>P</i><0.05), with deepened β-galactosidase staining and increased fluorescence intensity of reactive oxygen species. The proliferative capacity of cells in H<sub>2</sub>O<sub>2</sub>+CGF group on day 1, 3, 5 and 7 (0.23±0.01, 0.50±0.02, 1.60±0.07, 1.80±0.21) were all higher than in H<sub>2</sub>O<sub>2</sub> group (0.15±0.01, 0.14±0.02, 0.50±0.03, 0.90±0.09) (<i>P</i><0.05). Cell healing capacity of cells in H<sub>2</sub>O<sub>2</sub>+C","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"151-159"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20241010-00378
C Wang, T X Yan, W J Hu, D Shi, J S Zhong, J Kang
{"title":"[Correctly performing manual subgingival scaling and root planing exercises: part Ⅱ of a series on basic training in periodontal diagnosis and treatment].","authors":"C Wang, T X Yan, W J Hu, D Shi, J S Zhong, J Kang","doi":"10.3760/cma.j.cn112144-20241010-00378","DOIUrl":"10.3760/cma.j.cn112144-20241010-00378","url":null,"abstract":"<p><p>Periodontitis constitutes the primary cause of tooth loss among adults in China. The disease is characterized by the high morbidity, which significantly impairs both oral and systemic health. As the key insights of initial periodontal therapy, subgingival scaling and root planing (SRP) have been considered as simple, effective, and cost-efficient treatment approaches for managing periodontal inflammation. Substantial published evidences indicated that the majority of patients diagnosed with periodontitis could achieve lifelong retention of their natural teeth through standardized initial periodontal therapy, rigorous plaque control, and long-term supportive periodontal treatment. However, the proficiency in periodontal diagnosis and treatment among general dental practitioners in China is heterogeneous, with a notable scarcity of periodontists and a suboptimal level of SRP standardization. Drawing upon over four decades of clinical expertise from Peking University School and Hospital of Stomatology as well as comprehensive literature reviews, this paper meticulously outlines the standardized procedures for SRP, aiming at guiding clinicians to perform standardized SRP step by step, and thereby enhancing clinical efficacy of periodontal treatment, promoting periodontal health, and ultimately improving patients' quality of life.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"184-190"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20241217-00492
{"title":"[Clinical application standard of dynamic navigation technology in implant surgery].","authors":"","doi":"10.3760/cma.j.cn112144-20241217-00492","DOIUrl":"10.3760/cma.j.cn112144-20241217-00492","url":null,"abstract":"<p><p>Dynamic navigation technology can \"real-time guide\" the implantologist to place the implant in the alveolar bone of the missing tooth area according to the preoperative design of the optimal site and path, making the whole implant surgery process more safe and precise. In order to further promote the standardized application of oral implant dynamic navigation technology, China Association of Gerontology and Geriatrics has convened distinguished experts to engage in deliberations and develop the standard. This standard covers the basic requirements, indications and contraindications, operation procedures, common complications and treatment measures, and accuracy verification. This standard can be used as a reference for the use of dynamic navigation technology in implant surgery.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"105-108"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240611-000235
B X Huang, Z F Chen
{"title":"[Free gingival graft for augmenting peri-implant keratinized mucosa].","authors":"B X Huang, Z F Chen","doi":"10.3760/cma.j.cn112144-20240611-000235","DOIUrl":"10.3760/cma.j.cn112144-20240611-000235","url":null,"abstract":"<p><p>Insufficient keratinized mucosa is a common clinical problem. Although there is no consistent data on the long-term success of implant restorations relative to the presence or absence of peri-implant keratinized mucosa, it is widely accepted that the presence of keratinized mucosa width<2 mm is associated with increased biofilm accumulation, soft-tissue inflammation, and mucosal recession. Free gingival graft (FGG) is the standard surgical intervention for augmenting the width of keratinized gingiva. However, the clinical application of FGG is technique-sensitive. Therefore, this article describes the significance and efficacy, surgical timing, conventional procedures and techniques, common complications, as well as some modified approaches of the FGG, aiming to provide guidelines for its clinical application.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"191-196"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240612-00240
K Wu, H J Wu
{"title":"[Repair and reconstruction of anterior tongue defect with triangular muscle triangular flap: a case report].","authors":"K Wu, H J Wu","doi":"10.3760/cma.j.cn112144-20240612-00240","DOIUrl":"10.3760/cma.j.cn112144-20240612-00240","url":null,"abstract":"","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"169-171"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240802-00303
Y X Wang, T K Xu, J Li, T Jiang
{"title":"[Study on the occlusal stability after three years of full-mouth occlusal reconstruction in maximum intercuspal position].","authors":"Y X Wang, T K Xu, J Li, T Jiang","doi":"10.3760/cma.j.cn112144-20240802-00303","DOIUrl":"10.3760/cma.j.cn112144-20240802-00303","url":null,"abstract":"<p><p><b>Objective:</b> To observe the stability of vertical dimension of occlusion (VDO) and mandibular position in full-mouth occlusal reconstruction subjects by means of digital occlusal analysis. <b>Methods:</b> Six subjects who had completed full-mouth occlusal reconstruction by intraoral functional generated path technique for more than three years in the Department of Prosthodontics, Peking University School and Hospital of Stomatology were enrolled for follow-up observation, all six patients were male, with an age of (53.6±8.4) years. The digital dentition model and occlusal contact at baseline and three years follow-up review after restoration were recorded by intraoral laser scanning, and the changes in occlusal surface morphology, occlusal contact area and mandibular position (mandibular overall deviation and mandibular reference plane average angle deviation) were measured in reverse engineering software. The Wilcoxon signed rank test was used to statistically analyze the changes of horizontal and vertical overbite of anterior teeth and VDO of posterior teeth between baseline and three years follow-up after reconstruction. <b>Results:</b> The prosthesis in the 6 subjects were intact at the time of follow-up, and there was no significant change in occlusal morphology compared with that at the baseline right after restoration delivery, and the occlusal contact in maximum intercuspid position was stable. The overall deviation of the lower jaw was (0.19±0.06) mm, and the angular deviation of the mandibular reference plane was 0.72°±0.38°. The chromatic scale of occlusal contact showed that the occlusal contact in some areas was heavier during the three years post-delivery, and the overbite of anterior teeth and the VDO of posterior teeth showed no statistical difference compared with that in the baseline (all <i>P></i>0.05). <b>Conclusions:</b> This study suggests that the occlusal contact distribution and jaw position relationship can be maintained after 3 years of full-mouth occlusal reconstruction, and there is no significant change in the anterior overbite and VDO.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"132-139"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240815-00313
Y Wang, Y Wang, D Yang, J C Sun, L L Zheng
{"title":"[Atlantoaxial joint space and pharyngeal airway changes in skeletal class Ⅲ patients with mandibular deviation after combined orthodontic-orthognathic treatment: a cone-beam CT analysis].","authors":"Y Wang, Y Wang, D Yang, J C Sun, L L Zheng","doi":"10.3760/cma.j.cn112144-20240815-00313","DOIUrl":"10.3760/cma.j.cn112144-20240815-00313","url":null,"abstract":"<p><p><b>Objective:</b> To explore the changes of atlantoaxial joint spaces and pharyngeal airway after combined orthodontic-orthognathic treatment in skeletal class Ⅲ patients with mandibular deviation. <b>Methods:</b> A total of 34 adult skeletal class Ⅲ patients (10 males and 24 females) with mandibular deviation who received combined orthodontic-orthognathic treatment at the Department of Orthodontics and the Department of Orthognathic Surgery in the Stomatological Hospital of Chongqing Medical University from August 2014 to October 2021 were retrospectively selected. The patients were 22 (5) years old (18-33 years). Cone-beam CT data of patients taken before treatment (T0), after preoperative orthodontics (T1), and 6 to 12 months after orthognathic surgery (T2) were collected. The anterior atlanto-dental interval (ADI), variance of bilateral lateral atlanto-dental interval (VBLADI), the anterior posterior length (APL), maximum transverse width (LTW), aspect ratio (L/W), cross-sectional area (CSA) of each airway cross-section, the airway volumes, as well as the positions of the maxillofacial landmark points [subspinale (point A), supramental (point B), posterior nasal spine (point PNS), the most anterior and superior point of the hyoid bone (point H)] were measured at different time points. The correlations between airway changes, maxillofacial movements as well as the changes in the atlantoaxial joint spaces were also analyzed. <b>Results:</b> During the combined orthodontic-orthognathic treatment, no statistically significant differences were found in the ADI and VBLADI among different treatment time points (all <i>P></i>0.05). After preoperative orthodontics, the volume of total airway increased from 20 868 (6 669) mm<sup>3</sup> to 21 302 (8 911) mm<sup>3</sup> (<i>P<</i>0.05). After orthognathic surgery, there were no statistically significant differences in the APL, CSA of the PNS plane, the L/W of the uvula plane, and the nasopharyngeal airway volume compared with those after preoperative orthodontics (all <i>P></i>0.05). The L/W of the PNS plane after surgery was significantly increased compared with that after preoperative orthodontics (<i>P<</i>0.05), while other airway parameters were all significantly decreased compared with those after preoperative orthodontics (all <i>P<</i>0.05). Compared with before treatment, the nasopharyngeal airway volume after surgery [6 186 (1 707) mm³] increased significantly (<i>P<</i>0.05) and the palatopharyngeal airway volume [8 145 (2 594) mm³] and the glossopharyngeal airway volume [5 605 (4 395) mm³] decreased significantly (all <i>P<</i>0.05). There was no statistically significant difference in the total airway volume between after surgery and before treatment (<i>P></i>0.05). Correlation analysis showed that after preoperative orthodontics, the amount of the sagittal movement of point B was moderately positively correlated with the total airway volume change (<i>r=</i>0.40, <i>P=</i>0.022). Be","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"123-131"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-02-09DOI: 10.3760/cma.j.cn112144-20240708-00261
L H Chen, L J Zhang, Y X Zhang, J Shi
{"title":"[Role of thyroid peroxidase autoantibody in the comorbidities of pemphigus vulgaris and Hashimoto thyroiditis].","authors":"L H Chen, L J Zhang, Y X Zhang, J Shi","doi":"10.3760/cma.j.cn112144-20240708-00261","DOIUrl":"10.3760/cma.j.cn112144-20240708-00261","url":null,"abstract":"<p><p>Pemphigus vulgaris (PV) is a group of autoimmune bullous diseases characterized by life-threatening intradermal blisters. Hashimoto thyroiditis (HT) is a kind of autoimmune disease with abnormal increase of thyroid peroxidase autoantibody (TPOAb), which is the thyroid specific antibody, leading to hypothyroidism. In recent years, the probability of HT in patients with PV is increasing, and the co-disease may be related to the effect of TPOAb autoantibody on oral keratinocytes. This article reviews the epidemiological relationship between PV and HT and the mechanism of TPOAb in their co-disease, in order to provide ideas for the diagnosis and treatment of both.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 2","pages":"179-183"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}