中华口腔医学杂志最新文献

{"title":"[Research progress and frontier analysis of Laugier-Hunziker syndrome at home and abroad based on Citespace].","authors":"M M Zhao, X Wang, W M Wang","doi":"10.3760/cma.j.cn112144-20250116-00019","DOIUrl":"10.3760/cma.j.cn112144-20250116-00019","url":null,"abstract":"<p><p><b>Objective:</b> Analyzing the overview, changing trends, hotspots, and frontiers of the rare oral disease Laugier-Hunziker syndrome (LHS) using bibliometrics. <b>Methods:</b> Search the CNKI (China National Knowledge Infrastructure) and Web of science core collection (WOSCC) databases. The time span for Chinese literature is from January 1992 to December 2023, and for English literature is from January 1986 to December 2023. Utilize Citespace software to conduct visualized analysis on various aspects of the literature, including publication volume, authors, countries, institutions, journals, and keywords. <b>Results:</b> This study included a total of 112 articles (25 in Chinese and 87 in English). The overall publication volume showed a fluctuating slow-growth trend. Foreign authors Lenane P and Powell F had the highest number of publications. The team from Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, had the most publications among domestic authors. In terms of international collaboration, the United States demonstrated the highest centrality, but the collaborative network worldwide appeared relatively loose. University College Dublin was the foreign institution with the highest publication volume, while Peking Union Medical College Hospital was the domestic institution with the most publications. The journal with the highest number of foreign publications was the <i>Journal of The American Academy of Dermatology</i>, and the journal with the most domestic publications was the <i>Chinese Leprosy Skin Disease Journal</i>. Research hotspots for Laugier-Hunziker syndrome included lesion sites and differential diagnosis, while the frontiers of research encompassed differential diagnosis, disease management, and clinical manifestations related to oral mucosa. <b>Conclusions:</b> Laugier-Hunziker syndrome research shows a focus on differential diagnosis and symptom management. Future studies should prioritize optimizing treatment methods and emphasizing psychological support, while promoting interdisciplinary collaboration and the integration of global research networks to improve clinical diagnostic and therapeutic outcomes.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"273-281"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Classification of upper lip larger defect and the corresponding surgical plan].","authors":"K Wu, H J Wu","doi":"10.3760/cma.j.cn112144-20241217-00489","DOIUrl":"10.3760/cma.j.cn112144-20241217-00489","url":null,"abstract":"<p><p><b>Objective:</b> To classify the extensive defects after upper lip cancer surgery and explore the efficacy of nasolabial flap with Abbe flap combined or vermilion elastic flap in extensive defects after upper lip cancer ablation. <b>Methods:</b> Twenty-seven patients with upper lip cancer who underwent surgical resection in the Department of Oral and Maxillofacial, The Second Xiangya Hospital, Central South University from January 2010 to December 2021 were recruited, including 13 males and 14 females aged from 19 to 78 years old. The defects of upper lip were more than 50%, and local flaps (Abbe flap, nasolabial flap or vermilion elastic flap) were used to reconstruct the defects of upper lip cancer. According to the extent of defects and the application type of flaps, the defects were classified into 3 sub-types: ①Type Ⅰ defect: median upper lip defect, with more than 50% defect of vermilion and nearly complete defect of upper lip skin, which can be repaired by Abbe flap combined with double nasolabial flap.②Type Ⅱ defect: median upper lip defect, with more than 50% defect of vermilion and upper lip skin defect, repaired by Abbe flap alone. ③Type Ⅲ defect: lateral upper lip defect, with more than 50% defect of vermilion and upper lip skin defect. The nasolabial flap was used to reconstruct the skin defect, and the vermilion elastic flap was used to repair the labial redness defect. A four-point scale was used to evaluate the function and aesthetic outcome of the lips 3 months after surgery, and postoperative complications were recorded. <b>Results:</b> Among the included patients with lip cancer, there were 2 cases of type Ⅰ, 9 cases of type Ⅱ, and 16 cases of type Ⅲ. All Abbe flap and nasolabial flap survived, with tip necrosis occurring in 2 Abbe flaps and have been resected. The average functional score was 2.89±0.80, and the average cosmetic score was 3.04±0.76. <b>Conclusions:</b> The reconstructive method based on Abbe flap and nasolabial flap provides a novel surgical technique for the reconstruction of extensive defects after upper lip cancer surgery.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"262-266"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical analysis of 9 cases of paraneoplastic pemphigus with oral damage].","authors":"J Q Jin, Q Wang, J Liu, P Tong, Y X Zhang","doi":"10.3760/cma.j.cn112144-20241008-00375","DOIUrl":"10.3760/cma.j.cn112144-20241008-00375","url":null,"abstract":"<p><p><b>Objective:</b> Summarize the clinical characteristics, treatment methods, and prognosis of paraneoplastic pemphigus with oral lesions, and identify commonalities and features to provide better references for the clinical diagnosis and treatment of this disease. <b>Methods:</b> A retrospective analysis was conducted on the case data and clinical photos of 9 patients with paraneoplastic pemphigus accompanied by oral lesions treated in the Internal Medicine Ward and Department of Stomatology of Beijing Hospital from September 2017 to December 2023, and the clinical characteristics were summarized and analyzed. <b>Results:</b> All 9 patients had oral mucosal and skin lesions simultaneously, in whom visceral tumors were found upon systemic examinations, including 4 cases of Castleman's disease, 4 cases of thymoma, and 1 case of lung cancer. All patients had received glucocorticoid therapy before a clear diagnosis, but the effect was not significant. After removing the primary tumor, corticosteroid intravenous or oral therapies were usually continued, supplemented with immunoglobulin and immunosuppressants for treatment, which could achieve significant therapeutic effects. With primary tumor resection, 6 patients continued to receive corticosteroid intravenous or oral treatment for 6 to 12 months, supplemented with immunoglobulin and immunosuppressants. Oral mucosal erosion improved significantly and skin lesions were relieved. Three patients who were unable to remove their primary tumor continued with the previous glucocorticoid treatment regimen and died within one year. However, local treatment of their oral cavity during the treatment process still helped alleviate oral mucosal pain, promote erosion healing, and improve nutritional status. <b>Conclusions:</b> Multiple erosions of the oral mucosa and polymorphic skin damages are common clinical manifestations of paraneoplastic pemphigus. Castleman's disease and thymoma are common coexisting tumors. Early diagnosis and timely surgical resection of tumors are crucial for treatment and prognosis. The application of glucocorticoids and local oral treatment after resection is effective.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"248-253"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Role of periepithelial microenvironment changes in the malignant transformation of oral potential malignant disorders].","authors":"Y Chen, C Lou","doi":"10.3760/cma.j.cn112144-20241214-00481","DOIUrl":"10.3760/cma.j.cn112144-20241214-00481","url":null,"abstract":"<p><p>Oral potential malignant disorders (OPMDs) are a group of oral mucosal lesions with a risk of cancer transformation. The microenvironment surrounding the epithelial tissue is closely related to the malignant transformation of OPMDs. However, the changes and role of the periepithelial microenvironment during the malignant progression of OPMDs are not yet fully understood. This review discuss the impact of changes in the periepithelial microenvironment on the malignant transformation of OPMDs from following aspects: the immune microenvironment, stromal microenvironment, metabolic microenvironment, and oral microorganism. In the immune microenvironment, the immune surveillance capacity of periepithelial immune cells weakens, and some of these cells interact with malignant cells, resulting in an immunosuppressive microenvironment. Cells in the matrix promote the malignant transformation of OPMDs through the secretion of cytokines and nutritional support, along with extracellular matrix degradation and local angiogenesis. Epithelial cells undergo metabolic reprogramming during malignant transformation, while the resulting hypoxic microenvironment can further promote the malignant transition of epithelial cells. Oral microorganism fosters the malignant transformation of OPMDs by inducing inflammatory responses and creating hypoxic conditions.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"287-295"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Accurate evaluation model of burning mouth syndrome based on inflammatory factors and psychological scores: a clinical study].","authors":"Y Zhang, S Ye, H Sun, X M Shen, L Wu","doi":"10.3760/cma.j.cn112144-20241211-00469","DOIUrl":"10.3760/cma.j.cn112144-20241211-00469","url":null,"abstract":"<p><p><b>Objective:</b> To explore the correlation between anxiety, depression, and inflammatory markers in the body fluids of patients with burning mouth syndrome (BMS), creating a preliminary assessment model based on clinical data. <b>Methods:</b> Forty-one BMS patients were recruited according to the predefined inclusion criteria and exclusion criteria from the Department of Oral Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine between December 2021 and September 2023, along with 12 healthy controls. The pain intensity of the 41 patients was assessed using the visual analog scale (VAS). Meanwhile, anxiety and depression were assessed using the Zung self-rating anxiety scale (SAS) and the Zung self-rating depression scale (SDS). The concentrations of brain-derived neurotrophic factor (BDNF), interferon-γ (IFN-γ), interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor-alpha (TNF-α) in saliva and serum were measured using the Luminex 200^TM system and enzyme-linked immunosorbent assay. Statistical analyses were performed using the Chi-square test, independent samples <i>t</i>-test, ANOVA, Spearman's correlation analysis, and multiple linear regression, respectively. <b>Results:</b> The VAS score for the 41 BMS patients was (3.56±1.90), with 48.8% (20/41) and 41.5% (17/41) of patients experiencing mild and moderate pain, respectively. Only 7.3% (3/41) of patients had severe pain. Among the 41 BMS patients, 61.0% (25/41) exhibited anxiety and/or depression, in whom 39.0% (16/41) had both anxiety and depression, 9.8% (4/41) experienced anxiety without depression, and 12.2% (5/41) had depression without anxiety. The concentrations of IFN-γ and TNF-α in the serum and saliva of BMS patients were significantly higher than those in healthy controls (all <i>P<</i>0.05). In contrast, the BDNF concentration in serum was significantly lower in BMS patients than in healthy participants (<i>P<</i>0.01), but was significantly higher in saliva (<i>P<</i>0.001). Serum TNF-α was positively correlated with IFN-γ, IL-1β, and IL-6 (β=0.803, β=0.812, β=0.592; all <i>P<</i>0.01), while saliva TNF-α was negatively correlated with both anxiety and depression (β=-0.325, β=-0.321; all <i>P<</i>0.05). SAS scores were linearly correlated with saliva TNF-α concentrations (SAS=51.374-1.154×saliva TNF-α); saliva TNF-α concentrations were linearly correlated with saliva IFN-γ and IL-1β (saliva TNF-α=2.408+0.281×saliva IFN-γ+0.002×saliva IL-1β). <b>Conclusions:</b> This study provides a preliminary exploration of a clinical assessment model for BMS based on inflammatory markers and psychological scores, offering an exploratory framework for further research and optimization of the model.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"232-238"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in the study of polyetheretherketone and its composites in the field of dental implantology].","authors":"M Xue, J Chen, Y Y Zhang, Z H Zhang","doi":"10.3760/cma.j.cn112144-20240725-00294","DOIUrl":"10.3760/cma.j.cn112144-20240725-00294","url":null,"abstract":"<p><p>Polyetheretherketone (PEEK) and its composite materials have garnered widespread attention in the field of dental implantology due to their good biocompatibility, mechanical properties, and corrosion resistance. The low elastic modulus of PEEK, comparable to that of human jawbone, helps to reduce the stress shielding effect around the implant, thereby enhancing the rate of bone integration. This article reviews the latest research progress of PEEK and its composite materials in the field of dental implantation, including the synthesis of materials, surface modification techniques, and applications in implant-abutment-crown complexes and full-arch denture bridges.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"302-307"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparison of the accuracy of two types of scanning bodies for intraoral scanning in complete-arch implant-supported fixed restoration].","authors":"X J Fu, Z Z Cai, J Y Shi, H C Lai","doi":"10.3760/cma.j.cn112144-20240817-00315","DOIUrl":"10.3760/cma.j.cn112144-20240817-00315","url":null,"abstract":"<p><p><b>Objective:</b> To compare the accuracy of intraoral scanning for complete-arch implant-supported fixed prosthesis using umbrella scan bodies (USB) and conventional scan bodies (CSB), providing a reference for the clinical application of umbrella-shaped scanning bodies. <b>Methods:</b> A new type of umbrella-shaped scanning body and its matching auxiliary bar were independently developed. A maxillary type Ⅳ dental stone model with six parallel implant abutment analogs was fabricated. Conventional scanning bodies were installed on the model, and a laboratory scanner was used to scan the model as reference data. The CSB, USB, and USB combined with an auxiliary bar (U+SB) were installed on the model, respectively. A single attending physician performed intraoral scanning 10 times for each group using an intraoral scanner, serving as test group data (CSB, USB, U+SB). The test data were best-fit aligned with the virtual abutment models generated from the reference data. The trueness and precision of root-mean-square error (RMSE) values, inter-abutment distance deviations, angular deviations, and scanning time were measured and calculated. Repeated measures ANOVA and generalized estimating equation models were used for statistical analysis. <b>Results:</b> The trueness of RMSE values [(48.0±12.6) and (45.9±13.4) μm] and distance deviations [(64.5±60.2) and (63.8±54.4) μm] of the USB and U+SB groups were significantly better than those of the CSB group [(81.9±23.9) and (90.0±85.2) μm] (all <i>P</i><0.05). There was no significant difference in trueness of RMSE values and distance deviations between the USB group and U+SB group (all <i>P</i>>0.05). There were no significant differences in the precision of RMSE values and angular deviations among the three groups (all <i>P</i>>0.05). The scanning time of the USB group and U+SB group [(54.3±11.8) and (35.8±10.1) s] was significantly shorter than that of CSB group [(108.7±38.9) s] (all <i>P</i><0.05). <b>Conclusions:</b> Compared with conventional scanning bodies, the new umbrella-shaped scanning body demonstrates higher accuracy and efficiency for intraoral scanning impressions in complete-arch implant-supported fixed prosthesis.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"267-272"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Impact of different registration methods on the accuracy of virtual occlusal records in implant restoration for multiple missing teeth: an <i>in vitro</i> study].","authors":"J H Tian, Y P Mei, Y M Huang, Y Q Han, P Di, Y Lin","doi":"10.3760/cma.j.cn112144-20241007-00372","DOIUrl":"10.3760/cma.j.cn112144-20241007-00372","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the impact of four registration methods on the accuracy of virtual occlusal records (VOR) in intraoral scanning for implant restorations with multiple missing teeth. &lt;b&gt;Methods:&lt;/b&gt; A mandibular model simulating clinical conditions with multiple missing teeth (right first molar, left second premolar, left first molar, left second molar) and a maxillary compete dentition model were mounted on a semi-adjustable articulator. Subsequently, twelve 0.5 mm stainless steel spheres were adhered to reference positions (16, 46, 13, 43, 23, 33, 25, 35, 26, 36, 27, 37) as fiducial markers. Following this, a laboratory scanner generated reference datasets by digitizing the models in maximum intercuspation (MIP). Meanwhile, ten maxillary and mandibular scans were acquired using an intraoral scanner, with all nonarticulated scans duplicated four times to ensure data consistency. Forty VOR intraoral scans were performed in MIP using four registration protocols: left-side, right-side, anterior, and bilateral registration (&lt;i&gt;n&lt;/i&gt;=10 per group), randomized via a computer-generated pseudo-random sequence. For measurement, linear distances (D16-46, D13-43, D23-33, D25-35, D26-36, D27-37, D16-46 represented the single-tooth defect position, whereas D25-35, D26-36, D27-37 reflected positions in free-end edentulism areas) between opposing markers were measured in a reverse engineering software, with deviations (ΔD) from the reference scan calculated to assess accuracy. Specifically, negative ΔD values indicated vertical dimension underestimation. Given that non-normally distributed data were analyzed using medians [interquartile ranges (IQR)], trueness (median ΔD) and precision (IQR) were evaluated. The interaction effect between the registration method and the position of the measurement items was evaluated by using the generalized linear model. The accuracy was compared overall by the Kruskal-Wallis test with the two-sided significance level of α=0.05. For pairwise comparisons, post-hoc tests were conducted by Dunn's &lt;i&gt;t&lt;/i&gt;-test with the Bonferroni correction for the significance level. &lt;b&gt;Results:&lt;/b&gt; The accuracy of VOR was affected by registration method (&lt;i&gt;P&lt;/i&gt;&lt;0.05), with a significant position×registration method interaction observed (&lt;i&gt;P&lt;/i&gt;&lt;0.05). In particular, in all four groups, only the bilateral registration group showed trueness of less than 0.1 mm for both free-end edentulism and the single tooth defect, with ΔD16-46, ΔD25-35, ΔD26-36, and ΔD27-37 being 0.059 (0.015), -0.082 (0.052), -0.065 (0.032), -0.070 (0.050) mm, respectively. Moreover, trueness in free-end edentulism showed negative values across all groups, with the largest negative deviations observed in the right-side registration group, with ΔD25-35, ΔD26-36 and ΔD27-37 being -0.410 (0.174), -0.442 (0.225), -0.439 (0.262) mm, respectively. &lt;b&gt;Conclusions:&lt;/b&gt; In fully digital workflows of implant restorations for mandibular free-end edentulism with ","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"254-261"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Scale-invariant feature-enhanced deep learning framework for oral mucosal lesion segmentation].","authors":"R Zhang, L Jin, Q M Chen, T T Ding, Q Y Zhang, Y W Chen, X Tian, Y Y Cao, X Y Chen, F D Zhu","doi":"10.3760/cma.j.cn112144-20241210-00467","DOIUrl":"10.3760/cma.j.cn112144-20241210-00467","url":null,"abstract":"<p><p><b>Objective:</b> To develop PixelSIFT-UNet, a novel semantic segmentation model that integrates deep learning with scale-invariant feature transform (SIFT) algorithm to improve the segmentation accuracy of oral mucosal lesions. <b>Methods:</b> This investigation utilized 838 standard clinical white light images of oral mucosal diseases acquired from January 2020 to December 2022 at the Stomatology Hospital Zhejiang University School of Medicine. Randomization was achieved through Python's random.seed function implementation. The random sample function was subsequently applied for sampling distribution. The dataset was stratified into three subsets with a 6∶2∶2 ratio: training (<i>n</i>=506), validation (<i>n</i>=166), and testing (<i>n</i>=166). Lesion boundaries were annotated using Labelme software, and a PixelSIFT-UNet-based deep learning model was developed with VGG-16 and ResNet-50 backbone networks. Model parameters were optimized using the validation set, and performance metrics [including Dice coefficient, mean intersection over union (mIoU), mean pixel accuracy (mPA), and Precision] were assessed on the test set. The model's performance was benchmarked against conventional semantic segmentation frameworks (U-Net and PSPNet). <b>Results:</b> The developed PixelSIFT-UNet model could achieve precise segmentation of three common oral mucosal lesions: oral lichen planus, oral leukoplakia, and oral submucous fibrosis. Utilizing VGG-16 as the backbone network, the model achieved Dice coefficient, mIoU, mPA, and Precision values of 0.642, 0.699, 0.836, and 0.792, respectively. Implementation with ResNet-50 backbone network yielded metrics of 0.668, 0.733, 0.872 and 0.817, demonstrating significant improvements across all performance indicators compared to conventional U-Net model (relevant metrics: 0.662, 0.717, 0.861 and 0.809) and PSPNet model (relevant metrics: 0.671, 0.721, 0.858 and 0.813). <b>Conclusions:</b> The proposed PixelSIFT-UNet architecture demonstrates superior performance in oral mucosal lesion segmentation tasks, surpassing conventional semantic segmentation models and providing robust quantitative improvements in segmentation accuracy.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"239-247"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of multimodal medical image fusion in temporomandibular joint diseases].","authors":"W Zhao, X R Sun, Y Feng, W C Liu","doi":"10.3760/cma.j.cn112144-20241217-00495","DOIUrl":"10.3760/cma.j.cn112144-20241217-00495","url":null,"abstract":"<p><p>With the rapid development of modern technology, the deep integration of computer science and medicine has greatly propelled the field of the dental diagnostics field. Multimodal medical image registration refers to the fusion of information from various modalities of medical imaging. In other words, with the assistance of computer technology, the image data acquired from various radiological examinations undergo spatial registration and are merged to create a comprehensive new image, serving the purpose of computer-aided diagnosis. The temporomandibular joint (TMJ) has complex anatomical structures, so there is a wide range of diseases associated with it. Traditional single-modal imaging methods can only provide partial anatomical information, which limits the comprehensive assessment and subsequently hinders the diagnosis and treatment of TMJ diseases. Multimodal medical image registration techniques, owing to their ability to provide comprehensive information, have been widely applied in the field of dentistry. This has greatly enhanced the efficiency of diagnosing and treating TMJ diseases. The article discusses the advancements in the application of multimodal medical image registration in the context of TMJ diseases.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 3","pages":"296-301"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}