中华口腔医学杂志Pub Date : 2025-07-30DOI: 10.3760/cma.j.cn112144-20250103-00003
Z Huang, Q X Luan
{"title":"[Diversity and clinical practice of incision and flap design in periodontal regenerative surgery].","authors":"Z Huang, Q X Luan","doi":"10.3760/cma.j.cn112144-20250103-00003","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250103-00003","url":null,"abstract":"<p><p>This article reviews the recent advancements in incision and flap design for periodontal regenerative surgery, with a particular focus on the application of minimally invasive surgical techniques and non-crestal approaches. When applied to periodontal regeneration, traditional flap designs, such as the modified Widman flap, present disadvantages including wound dehiscence and gingival recession, compromising regenerative outcomes. To address these issues, researchers have developed a series of novel techniques, including papilla preservation techniques, minimally invasive techniques, and single-flap techniques. However, these techniques usually involve horizontal or oblique incisions near the interdental papilla adjacent to the intrabony defect, which may still lead to wound dehiscence, limiting periodontal regeneration. Also they may cause gingival recession and reduction in papilla height, resulting in \"black triangles\". In recent years, a series of new techniques utilizing non-crestal approaches have emerged, altering incision placement to preserve the interdental papilla. Examples include the entire papilla preservation technique using a lateral incision approach, non-incised papilla surgical approaching by an apical incision, and apically incised coronally advanced surgical technique. By placing incisions away from the papilla, these methods achieve complete papilla preservation and provide greater space for regeneration, effectively promoting the regeneration of both intrabony and suprabony periodontal tissues. This article systematically analyzes the key surgical points, indications, and clinical efficacies of different incision designs in periodontal regenerative surgery. Detailed case presentations illustrate the step-by-step procedures of these techniques, demonstrating their favorable outcomes in treating intrabony defects. The aim is to encourage future clinical studies to validate the effectiveness and safety of these novel techniques.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"846-856"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-30DOI: 10.3760/cma.j.cn112144-20241025-00401
Y X Wang, Y L Wang, S M Yu, Y Y Zhao, Y F Zhang, Q Yan
{"title":"[Effect of cone beam CT registration versus intraoral scanning registration on implant accuracy in robot-assisted surgery: a study using simulated skull models].","authors":"Y X Wang, Y L Wang, S M Yu, Y Y Zhao, Y F Zhang, Q Yan","doi":"10.3760/cma.j.cn112144-20241025-00401","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20241025-00401","url":null,"abstract":"<p><p><b>Objective:</b> To compare the effects of using cone beam CT (CBCT) and oral scanning registration on implant positional accuracy during robot-assisted implant surgery, and to provide a basis for selecting the appropriate registration for robot-assisted implant surgical options. <b>Methods:</b> One patient with dentition defect, specifically missing teeth at positions 21 and 26 and having natural teeth adjacent mesially and distally to the edentulous area, who visited the Department of Oral Implantology, School of Hospital of Stomatology Wuhan University in 2024 were selected. Based on reconstructed imaging data, 30 identical jaw models were printed. These models were divided into a CBCT registration group and an intra-oral scanning registration group (15 models per group). An associate chief physician with extensive experience in implant surgery performed preoperative registration using the implant robot and completed the implant surgeries. Postoperative CBCT scans were used to determine the three-dimensional position of the implants. The deviations between the planned implant position and the actual position were evaluated, including deviations at the implantation point, apical point, and angular deviation. The differences between the two groups were compared. <b>Results:</b> The implantation deviation was 0.675 (0.490) mm, apical deviation was (0.680±0.272) mm, and the angular deviation was 0.566°±0.147° in the CBCT registration group, and in the intra-oral scanning registration group, implantation deviation was 0.695 (0.313) mm, apical deviation was (0.667±0.217) mm, and the angular deviation was 0.523°±0.168°. There was no statistically significant error in implant precision between the two groups (<i>P</i>>0.05). <b>Conclusions:</b> This <i>in vitro</i> experiment found that the use of intra-oral scanning registration in robot-assisted implant surgery can achieve similar implant placement accuracy as CBCT registration.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"857-862"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-30DOI: 10.3760/cma.j.cn112144-20250401-00112
J Chen, Y C Chen, J Qian, W N Fu, W F Chen, X X Li
{"title":"[Preliminary investigation on the effect of zirconium-based colorants on the colorimetric properties of fused deposition modeled polyetheretherketone composites].","authors":"J Chen, Y C Chen, J Qian, W N Fu, W F Chen, X X Li","doi":"10.3760/cma.j.cn112144-20250401-00112","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250401-00112","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the effect of zirconium-based pigments with different mass fractions on the colorimetric properties of fused deposition modeling (FDM) polyetheretherketone (PEEK) composites, and to investigate the feasibility of using these pigments for computer color matching of PEEK composites. <b>Methods:</b> Specimens were fabricated using FDM technology, comprising two control groups [Pure PEEK group, PEEK-TiO<sub>2</sub> group (PEEK compounded with 20% TiO<sub>2</sub>)] and nine experimental groups based on the type of zirconium-based pigment (zirconium praseodymium yellow, zirconium iron red, zirconium vanadium blue) and mass fraction (0.1%, 0.5%, 1.0%). The experimental group specimens consisted of PEEK blended with 20% TiO<sub>2</sub> and the respective zirconium-based pigment. The spectral reflectance curve and chromaticity values of all specimens were measured using a spectrophotometer. The relationship between the chromaticity values of each colored PEEK composite in the experimental groups and the pigment mass fraction was determined. Shade guide tabs mimicking clinically used tooth shades were fabricated using a light-curing resin (Filtek Z350XT Body). The full-spectrum color matching method was employed to calculate the PEEK composite formulations (PEEK, 20% TiO<sub>2</sub>, blends of the three zirconium-based pigments) required to match these target tooth shades. Verification group specimens based on these calculated recipes were then fabricated. The color difference between each verification group specimen and its corresponding target shade tab was calculated. Color differences between the target shade tabs and the two control groups (Pure PEEK, PEEK-TiO<sub>2</sub>) were also calculated. <b>Results:</b> The spectral reflectance curves of PEEK composite specimens containing different types of zirconium-based pigments exhibited distinct characteristic features. The chromaticity values were significantly affected by the mass fraction of the same zirconium-based pigment. Based on computer color matching calculations, the color differences between the verification group specimens and the target shade tabs ranged from 1.59 to 14.55. <b>Conclusions:</b> This study demonstrates the feasibility of utilizing the three zirconium-based pigments (zirconium praseodymium yellow, zirconium iron red, zirconium vanadium blue) for full-spectrum computer color matching of PEEK-TiO<sub>2</sub> composites.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"879-885"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-30DOI: 10.3760/cma.j.cn112144-20241217-00493
X Pan, Z T Lin, S F Zhao
{"title":"[Cone-beam CT image analysis of 226 cases of mandibular second and third molar association area].","authors":"X Pan, Z T Lin, S F Zhao","doi":"10.3760/cma.j.cn112144-20241217-00493","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20241217-00493","url":null,"abstract":"<p><p><b>Objective:</b> To explore the imaging characterization of mandibular third molar (M3) and mandibular second molar (M2) and their associated areas using cone beam CT (CBCT). <b>Methods:</b> A total of 226 images of patients with concomitant mandibular second and third molars in the Department of Oral and Maxillofacial Medical Imaging of Nanjing Stomatology Hospital were selected to retrospectively analyze their clinical information and imaging manifestations from January 2020 to January 2024, and their clinical information and imaging performances were analyzed. Clinical information included patient's age, gender, and chief complaint; dental tissues (crowns, roots) and periodontal tissues (periodontium, alveolar bone) of the mandibular second molar were evaluated based on their CBCT, and the position (high, medium, low), type of obstruction, dental tissues, periodontal tissues and bone margins of the alveolar bone between them, extent (concave, oblique, flat) and depth of bone defects, and periodontal membrane imaging changes of the mandibular third molars etc. <b>Results:</b> There were 104 cases of mandibular M2 and M3 as the main complaints and 122 cases of non-main complaints in this study. According to the imaging aspects, the mandibular M2 and M3 associated regions with abnormal CBCT imaging manifestations were mainly categorized into six sagittal representation phenotypes (types Ⅰ-Ⅵ); among them, middle-aged and elderly patients≥45 years of age more often showed abnormal imaging phenotypes (75%), and the peripheral bone defects were more severe. The correlation between the type and height of the mandibular M3 obstruction (high:medium:low=42∶110∶74) and the imaging typology of the mandibular M2 and M3 association regions was statistically significant (<i>P<</i>0.001). The bone defects between mandibular M2 and M3 of the young patients≤25 years of age were predominantly of the oblique type of resorption (41/69 cases), and the least of the flat type (1/69 cases), whereas flat type could reached 27.8% in the middle-aged and elderly patients≥45 years of age, and the circumferential angle of the peripheral bone defects in the mandibular M2 and M3 regions showed strong correlation with age (<i>P<</i>0.001), typology (<i>P<</i>0.001), and the height of the obstruction (<i>P=</i>0.004). The correlation between defect depth and obstruction height for the same fractal type was statistically significant in the age groups≤25 years and 26-44 years (<i>P</i><sub>≤25 years</sub>=0.0385, <i>P</i><sub>26~44 years</sub>=0.032). There was a significant correlation between mandibular M3 with different types of obstruction, especially proximal-medial (34/43 cases) and horizontal obstruction (8/43 cases), and neighboring M2 suffering from caries (<i>P=</i>0.004). The correlation between obstruction height (median 46.3%, low 50.0%) and M2 extra-root resorption (80 cases) was statistically significant (<i>P<</i>0.001). <b>Conclusions:</b> In this study, we","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"905-914"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-30DOI: 10.3760/cma.j.cn112144-20250109-00008
Sihan Yu, Liwei Zheng, Mian Wan
{"title":"[Effects of microplastics exposure on development of mineralized tissues].","authors":"Sihan Yu, Liwei Zheng, Mian Wan","doi":"10.3760/cma.j.cn112144-20250109-00008","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250109-00008","url":null,"abstract":"<p><p>(microplastics),、,,。。,,,。,A,、,。,。,。.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"928-934"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-30DOI: 10.3760/cma.j.cn112144-20250423-00152
B B Li, Y H Shan, Y S Zhou
{"title":"[Zheng Linfan's contribution to the strategic thinking of innovative development in oral science].","authors":"B B Li, Y H Shan, Y S Zhou","doi":"10.3760/cma.j.cn112144-20250423-00152","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250423-00152","url":null,"abstract":"<p><p>Professor Zheng Linfan has played an important role in pioneering and leading the development of dentistry in China. In the early 1940s, he spearheaded groundbreaking investigations on the oral health status of Chinese students, and guided fundamental researches by clinical issues which led to the establishment of China's first oral histopathology laboratory and the Institute of Stomatology. His remarkable scholarly achievements earned him the National Medical and Health Science Conference Award in 1978. He attached great importance to \"investigation and clinical practice\", \"basic research-driven\", \"interdisciplinary\" and \"international cooperation and exchange\" in the early stage of the development of oral science in China, and therefore formed a four-in-one innovative idea, making important contributions to the innovative research and clinical development of Chinese stomatology. This article bases on professor Zheng Linfan's work and research experience. Through the excavation of archival documents, correspondence, memoirs, historical records, and oral history materials, this article reconstructs his contributions to stomatology in China, and summarizes his academic ideas, practical paths, and ideological values in promoting the construction of the stomatological development system, providing references for enriching the historical narrative of stomatology in China, and assisting contemporary advancements and technological innovation.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"915-920"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-09DOI: 10.3760/cma.j.cn112144-20250411-00132
X J Zhang, T T Wu, Y Zhang, R Q Guo, Z Yin, Y Zhao, J Wang, T J Li, H M Liu, X C Guo, X H Zhang, W Hou, T T Liu, X F Ma, X H Liu
{"title":"[Comparison of magnetic resonance images of the temporomandibular joint using different coils].","authors":"X J Zhang, T T Wu, Y Zhang, R Q Guo, Z Yin, Y Zhao, J Wang, T J Li, H M Liu, X C Guo, X H Zhang, W Hou, T T Liu, X F Ma, X H Liu","doi":"10.3760/cma.j.cn112144-20250411-00132","DOIUrl":"10.3760/cma.j.cn112144-20250411-00132","url":null,"abstract":"<p><p><b>Objective:</b> To explore and compare the clinical application value of 8-channel head phased-array coil, an 8-channel temporomandibular joint (TMJ)-specific surface coil, and a single-channel surface coil in TMJ MRI examinations. <b>Methods:</b> A total of 600 temporomandibular disorders (TMD) patients (1 200 joints) who underwent TMJ MRI examination in the First People's Hospital of Jinzhong from June 2020 to January 2025 were retrospectively screened. Based on inclusion/exclusion criteria, 120 TMD patients (240 joints) with closed-mouth oblique sagittal proton density weighted imaging (OSag PDWI), coronal T2 fat-suppression weighted imaging (OCor fs T2WI) and open-mouth oblique sagittal proton density weighted imaging (OSag PDWI) were included. Patients were divided into groups A, B, and C, with 40 cases in each group. Group A (31female, 9male, median age 24 years old), underwent 8-channel head phased-array coil imaging. Group B (29 female, 11male, median age 23.5 years old) underwent TMJ imaging with an 8-channel surface coil. Group C (29 female, 11male, median age 22.5 years old) underwent single-channel surface coil imaging. There were no significant differences in age, gender, type or disease types among groups (<i>P></i>0.05). Six healthy volunteers without TMD (4 female, 2 male, range 19 to 45 years old) underwent imaging with all three coils as self-control. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and image quality were compared for five regions of interest (ROI) in both patients and volunteers. <b>Results:</b> Under the same sequence and the same parameters, SNR and CNR in group B were higher than those in group A, and SNR and CNR in group C were also higher than those in group A, the differences were statistically significant (<i>P<</i>0.05). However, there were significant differences in SNR and CNR between group B and group C in the closed and open positions of ROI1, the open positions of ROI3 and the open positions of ROI5 (<i>P<</i>0.05), and there were no significant differences in other positions (<i>P></i>0.05). Group B had the best image quality, followed by group C and group A had the worst image quality. There were significant differences in the visualization of OSag PDWI in the closed mouth position, OCor T2WI in the coronal position, and OSag PDWI in the open mouth position, such as condyle, anterior attachment, joint disc, double lamina area, joint cavity and lateral pterygoid muscle (<i>P<</i>0.05). There were significant differences between group B and group C in showing the joint cavity in the closed mouth position and showing the structure of the bilaminar area in the open mouth position (<i>P<</i>0.05). There was no significant difference in other regions of interest (<i>P></i>0.05). The subjective scores of condyle, anterior attachment, articular disc, bilaminar area, articular cavity, lateral pterygos muscle and other structures were medium to high in group A, high in group B, and hi","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"713-722"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-09DOI: 10.3760/cma.j.cn112144-20250313-00079
M Q Liu, Y J Jiang, K K Ma, Y Luo, Z Y Chen
{"title":"[A bibliometric analysis of research progress in temporomandibular disorders: 2010-2024].","authors":"M Q Liu, Y J Jiang, K K Ma, Y Luo, Z Y Chen","doi":"10.3760/cma.j.cn112144-20250313-00079","DOIUrl":"10.3760/cma.j.cn112144-20250313-00079","url":null,"abstract":"<p><p><b>Objective:</b> To analyze research trends, hotspots, and international collaboration in temporomandibular disorders (TMD) from 2010 to 2024 using bibliometric methods. <b>Methods:</b> A total of 4 368 articles published between January 2010 to December 2024 were retrieved from PubMed using the search strategy temporomandibular disorders[MeSH Terms] OR temporomandibular joint disorders[Title/Abstract]. The R package\"bibliometrix\" was employed to analyze publication statistics, author collaboration networks, and keyword co-occurrence. <b>Results:</b> The annual publication volume in the TMD field increased 3.4-fold from 2010 to 2024, with an average annual output of 291.2 articles. MANFREDINI DANIELE was identified as the most prolific author (74 articles). The <i>Journal of Oral Rehabilitation</i> ranked first in terms of publication quantity (454 articles). The University of São Paulo (Brazil) emerged as the leading contributor, followed by Sichuan University (China) globally. Research hotspots predominantly focused on the DC/TMD diagnostic criteria and pain mechanisms. Analysis of international collaboration networks revealed that core authors (e.g., Lobbezoo F, Manfredini D) have driven advancements in the field through multidisciplinary collaboration (dentistry+psychology+medical imaging). The high-frequency occurrence of the imaging keyword \"magnetic resonance imaging (MRI)\" underscores its pivotal role in diagnosing disc displacement. Chinese institutions (Sichuan University, Peking University) ranked second globally in research output; however, interdisciplinary international collaboration remained limited, with multiple-country publications (MCP) accounting for only 13.0%. <b>Conclusions:</b> TMD research demonstrates interdisciplinary integration, highlighting the need for future emphasis on Asian population studies and innovative diagnostic/therapeutic technologies.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"723-730"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-09DOI: 10.3760/cma.j.cn112144-20250206-00037
H X Hong, G B Liu, K M Li
{"title":"[Multidisciplinary treatment of a class Ⅱ division 2 patient with temporomandibular disorders].","authors":"H X Hong, G B Liu, K M Li","doi":"10.3760/cma.j.cn112144-20250206-00037","DOIUrl":"10.3760/cma.j.cn112144-20250206-00037","url":null,"abstract":"","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"775-780"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华口腔医学杂志Pub Date : 2025-07-09DOI: 10.3760/cma.j.cn112144-20250319-00092
K Jiao
{"title":"[Multidimensional analysis of cranio-maxillofacial joint-neural interactions and their clinical significance].","authors":"K Jiao","doi":"10.3760/cma.j.cn112144-20250319-00092","DOIUrl":"10.3760/cma.j.cn112144-20250319-00092","url":null,"abstract":"<p><p>The interplay between the skeletal and nervous systems has emerged as a pivotal area in modern medical research. Unlike mesodermal-origin trunk skeletons, craniofacial bones demonstrate distinctive neurobiological properties due to their unique embryonic origin from ectodermal neural crest cells. This article systematically investigates the interaction mechanisms between craniofacial bones and the nervous system across developmental, anatomical, and functional dimensions. It comprehensively elaborates the translational value of this neuro-skeletal association in advancing precision diagnosis and treatment for various pathologies, including temporomandibular joint osteoarthritis, craniofacial bone trauma, and dentition defect restoration. The findings propose novel strategies spanning molecular regulation to clinical translation, offering innovative perspectives for managing craniofacial disorders.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"697-703"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}