中华口腔医学杂志最新文献

{"title":"[Study on the current status of health education needs among patients after debridement and suture for maxillofacial soft tissue trauma].","authors":"Y L Shi, Q Y Xiong, Y J Diao, X R Zhou, X Liu","doi":"10.3760/cma.j.cn112144-20251229-00534","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20251229-00534","url":null,"abstract":"<p><p><b>Objective:</b> To systematically investigate the current status of postoperative health education needs among patients with maxillofacial trauma, so as to provide evidence for establishing staged and individualized clinical health education programs. <b>Methods:</b> A cross-sectional survey was conducted among 469 patients with maxillofacial trauma admitted to the Emergency Department of West China Hospital of Stomatology, Sichuan University from January to May 2025. Data were collected using a validated health education needs questionnaire for patients with maxillofacial trauma. Medians and interquartile ranges were used for descriptive statistics; nonparametric tests were applied for group comparisons, and Spearman rank correlation was used for correlation analysis. <b>Results:</b> The median age of the included patients was 6.0 years old, and 78.7%(369/469) of patients were under 18 years old. The most frequent injury site was the lower third of the face, accounting for 51.0%(239/469). The median scores of items V1-V8 and V10-V20 were all 5.0. Gender had no significant effect on the scores of health education needs (<i>P</i>>0.05). Age-stratified analysis showed that 13 items (V1, V4, V10-V20) had significantly higher scores in patients under 18 years old than in those aged 18 years and older (all <i>P</i><0.05). All items (V1-V20) differed significantly among postoperative time stages (all <i>P</i><0.05), with scores immediately after operation consistently higher than those at 6 days or more postoperatively (all <i>P</i><0.05). Regarding injury sites, significant differences were found in items V6 and V17 (all <i>P</i><0.05), Patients with injuries in the upper third of the face had higher needs for pharmacological and non-pharmacological management of postoperative scars than those with injuries in the lower third (<i>P</i><0.05). Correlation analysis revealed that health education needs for items V1-V3, V8, and V10-V20 were negatively correlated with age (<i>P</i><0.05), and all items V1-V20 were negatively correlated with postoperative time (<i>P</i><0.05). <b>Conclusions:</b> Postoperative health education needs in patients with maxillofacial trauma are influenced by age, postoperative time, and injury site. Clinical practice should abandon the one-size-fits-all education model and establish staged, individualized health education focused on the early postoperative period and targeted at children and adolescents, so as to improve rehabilitation outcomes and quality of life.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"648-654"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Guidelines for the design and clinical protocols of surgical guides in crown lengthening via digital workflow(2026)].","authors":"","doi":"10.3760/cma.j.cn112144-20260127-00051","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260127-00051","url":null,"abstract":"<p><p>Crown lengthening serves as a key procedure for addressing aesthetic concerns such as gummy smile, short clinical crowns, and uneven gingival contours. Advances in digital technology, particularly computer-aided design and computer-aided manufacturing (CAD/CAM), now allow precise translation of preoperative plans into surgical execution, enabling accurate control over gingival margin and alveolar ridge positioning. To standardize the clinical application of this technology, the Chinese Society of Digital Dental Industry (CSDDI) convened a panel of experts to develop this guideline document. It aims to define steps for digital data acquisition, integration, and design in guided crown lengthening within the aesthetic zone; standardize the digital workflow for designing surgical guides for aesthetic crown lengthening; assist clinicians in formulating appropriate digital surgical plans through thorough digital analysis and diagnosis; and offer practical guidance on performing crown lengthening surgery using digital guides in aesthetic areas. Ultimately, this guideline seeks to standardize the surgical protocol for digital guide assisted crown lengthening, thereby improving procedural accuracy and predictability of treatment outcomes.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"611-618"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A decade review and prospect of Oral Emergency Medicine in China].","authors":"Y J Chen, Y Q Zhu, D S Yu, Y Zhang, W He, Q Li, Y J Zhao","doi":"10.3760/cma.j.cn112144-20260214-00117","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260214-00117","url":null,"abstract":"<p><p>The past decade has been a critical period for Oral Emergency Medicine in China, marked by a transition from decentralized practice to systematic development and from experience-based care to guideline-oriented approaches. With the establishment of the Society of Oral Emergency Committee of Chinese Stomatological Association in 2016 as a milestone, the discipline oral emergency medicine has achieved remarkable progress in academic development, clinical services, personnel training, and scientific research. These achievements include the establishment of a discipline connotation tailored to Chinese specific conditions, continuous improvement in diagnostic and therapeutic standards and service accessibility, steady advancement in standardization, the initial formation of a professional workforce, and a significant increase in international influence. Meanwhile, the discipline still faces challenges, including an underdeveloped theoretical framework, imbalanced regional resource allocation, a shortage of specialized professionals, and imperfect multidisciplinary collaboration mechanisms. Drawing on international practices related to oral emergencies and the development experience of emergency medicine in China, this article proposes future goals for discipline construction: establishing a clear disciplinary status, building a systematic theoretical framework, improving the clinical service chain, strengthening the personnel training mechanism, and building scientific research platforms. These efforts aim to advance oral emergency medicine in China from initial establishment to mature development, providing robust support for the\"Healthy China\"strategy.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"619-626"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Visual analysis of global research hotspots and development trends in dental trauma].","authors":"X L Wan, F X Zhou, X R Zhou, W W Jiang, X Liu, L L Feng, Y L Shi","doi":"10.3760/cma.j.cn112144-20260103-00002","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260103-00002","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the current global development status and research hotspots of dental trauma-related studies, to provide references for future research in this field in China. <b>Methods:</b> Literature related to dental trauma, published from the inception of the Web of Science Core Collection up to December 27, 2025, was retrieved. Visualization analysis was conducted using Bibliometrix, VOSviewer, CiteSpace, and Excel. <b>Results:</b> A total of 2 639 publications were included. The annual publication output showed an overall increasing trend with fluctuations. Levin L was the most prolific author, the Universidade Federal de Minas Gerais was the leading institution, and Brazil was the most productive country/region. Andreasen JO was the most frequently co-cited author, <i>Dental Traumatology</i> was the most frequently co-cited journal, and the reference by Petti et al (2018) was the most frequently co-cited. The top five high-frequency keywords were: \"dental trauma, \" \"teeth, \" \"traumatic dental injury, \" \"injury, \" and \"children.\" The top five keywords with the highest centrality were: \"children, \" \"dental trauma, \" \"adolescents, \" \"tooth avulsion, \" and \"emergency management.\" The log-likelihood ratio (LLR) algorithm identified 15 keyword clusters, with \"pediatric dentistry\" emerging as a burst keyword in 2023. <b>Conclusions:</b> Current global research on dental trauma shows a diversified development trend. In the future, China can further deepen its research in areas such as regenerative medicine, the clinical application of novel biomaterials, precision diagnosis and treatment, multidisciplinary management models, long-term prognosis evaluation, and intelligent assisted diagnosis and treatment.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"669-677"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Three-dimensional finite element analysis of the protective performance of two types of mouthguards].","authors":"P Y Yan, S S Zhang, Y L Liu, Y Yang, Y J Wang, M Zhang","doi":"10.3760/cma.j.cn112144-20260120-00035","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260120-00035","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the biomechanical characteristics of thermoformed mouthguards and three-dimensional (3D)-printed mouthguards through the 3D finite element method (FEM), and to provide a theoretical basis for the selection of mouthguards in clinical and sports scenarios. &lt;b&gt;Methods:&lt;/b&gt; A healthy male student volunteer aged 24 years was recruited in the Xi'an Physical Education University in January 2024, and the volunteer signed a written informed consent form. Both types of mouthguards were custom-made individually: the thermoformed mouthguard was fabricated using a traditional vacuum thermoforming process, and the 3D-printed mouthguard was fabricated using a stereolithography 3D printing process. The volunteer wore the two types of mouthguards respectively, and after confirming that the mouthguards fit well and the occlusion was stable, CT scanning of the maxilla and mandible was performed with a spiral CT scanner. 3D finite element models containing the teeth, jaw bones, temporomandibular joint (TMJ) articular disc and the corresponding mouthguards were established based on the acquired CT tomographic scan data. A constant load of 800 N perpendicular to the coronal plane of the human body with a duration of 0.15 s was applied to the lateral region corresponding to the anterior tooth area of the two mouthguard models to simulate the mechanical state of the anterior tooth area under impact in boxing. The magnitude and distribution law of stress on the teeth, jaw bones and TMJ articular disc under the protection of the two mouthguards during impact were compared and analyzed. &lt;b&gt;Results:&lt;/b&gt; There were significant differences in the biomechanical performance of the 3D finite element models corresponding to the two types of mouthguards when the load was applied to the lateral region corresponding to the anterior tooth area of the mouthguards. Under the protection of the thermoformed mouthguard, stress concentration was observed in the maxillomandibular-dental hard tissue complex, the cervical region of the mandibular anterior teeth, as well as the condylar side and glenoid fossa side of the TMJ articular disc. The peak von Mises stress of the maxillary anterior teeth was 75.382 MPa, and obvious stress accumulation was detected on the condylar side and glenoid fossa side of the articular disc, with the peak stress values of 0.531 MPa and 0.476 MPa respectively. Under the protection of the 3D-printed mouthguard, the stress was uniformly dispersed in the maxillomandibular-dental hard tissue complex and the mesial and distal sides of the articular disc. The peak von Mises stress of the maxillary anterior teeth was 73.262 MPa, no obvious stress concentration was found on the glenoid fossa side of the articular disc, and the stress on the condylar side was evenly distributed in the mesial and distal regions of the articular disc. &lt;b&gt;Conclusions:&lt;/b&gt; The 3D-printed mouthguard has better protective performance, which can effectively","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"661-668"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Physiological age estimation model on pediatric panoramic radiographs based on machine learning and deep learning].","authors":"X Q Zeng, B Xia, Z Q Cao, T Y Ma, Z N Xu, H L Bai, P Ding, J X Zhu","doi":"10.3760/cma.j.cn112144-20250709-00257","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250709-00257","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To automatically estimate children's physiological age from pediatric panoramic radiographs, employing a two-stage approach which involves permanent teeth staging assessment followed by physiological age conversion, as well as an end-to-end approach. &lt;b&gt;Methods:&lt;/b&gt; From 3 367 radiographs of children aged 4 to 11 years, collected at Pediatric Dentistry, Peking University School and Hospital of Stomatology, between November 2012 and August 2020, 640 images were randomly assigned into training set-1 (392 images), validation set-1 (118 images), and test set-1 (130 images) using Python (version 3.9) scripts. Using manual annotations of Demirjian's stages for 8 left mandibular teeth as gold standard, a YOLOv5-based deep learning model (staging-judgment-model) was trained and validated, whose performance was assessed using metrics including accuracy and weighted &lt;i&gt;Kappa&lt;/i&gt;. Using chronological age as ground truth, random forest models (age-machine-models) were developed based on automatic staging of teeth 31-37 or 31-38. The full dataset (3 367 images) was randomly allocated into training set-2 (2 031 images), validation set-2 (673 images), and test set-2 (663 images) to train a ResNet-50-based deep learning model (age-deep-model). An external test set (907 images) from the Clinical Division Peking University School and Hospital of Stomatology from June 2022 to December 2022 was collected. Performance was assessed using mean absolute error (MAE), root mean square error (RMSE), and coefficient of determination (&lt;i&gt;R²&lt;/i&gt;). Class activation maps were used to reveal the areas of concern for the age-deep-model. Images with an absolute difference between inferred and actual ages exceeding 3 standard deviations from the mean difference were selected for manual reviews. &lt;b&gt;Results:&lt;/b&gt; The staging-judgment-model achieved an overall accuracy of 75.95%, with a linear-weighted &lt;i&gt;Kappa&lt;/i&gt; of 0.87 and quadratic-weighted &lt;i&gt;Kappa&lt;/i&gt; of 0.95. In the test set-1, the MAE, RMSE and &lt;i&gt;R²&lt;/i&gt; of the age-machine-models based on automatic staging of teeth 31-37 were 0.592 years, 0.757 years and 0.879, while ones of the age-machine-models based on automatic staging of teeth 31-38 were 0.594 years, 0.754 years and 0.879. In the test set-2, the MAE, RMSE and &lt;i&gt;R²&lt;/i&gt; of the age-deep-model were 0.621 years, 0.800 years and 0.918 respectively. The gradient class activation map revealed that the areas of concern for age-deep-model gradually shifted from the crown of the posterior deciduous teeth to the apical area of the posterior permanent teeth with increasing age. The staging-judgment-model might mistake later teeth development stages for earlier ones, resulting in an underestimated assessment of physiological age by age-machine-models. Similarly, orthodontic appliance images might lead the age-deep-model to generate an underestimated age estimation. &lt;b&gt;Conclusions:&lt;/b&gt; This study enabled fully automated physiological age inference via two compl","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"696-705"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A retrospective analysis of the prognosis of regenerative endodontic treatment for pulp necrosis following dental trauma].","authors":"W W Zhou, Y X Zhang, S Li, L Y Jin, L L Zhang","doi":"10.3760/cma.j.cn112144-20260124-00046","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260124-00046","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the clinical outcomes of regenerative endodontic treatment (RET) for traumatized immature permanent teeth and to identify key prognostic factors, specifically the influence of trauma type on therapeutic efficacy. <b>Methods:</b> A single-center retrospective cohort study was conducted. Teeth with trauma-induced pulp necrosis that received standardized RET at the Department of General Dentistry and Integrated Emergency Dental Care, Capital Medical University School of Stomatology from January 2018 to December 2022 were consecutively enrolled. A total of 130 teeth from 115 patients were included. The patients' ages ranged from 7 to 13 years, and the follow-up period ranged from 12 to 84 months. Treatment outcomes were categorized as ideal healing, effective healing (disease control), or failure. Nonparametric tests were used for univariate analysis, while multivariable logistic regression and Kaplan-Meier survival analysis were performed for multivariable and survival analyses, respectively. <b>Results:</b> Univariate analysis showed that trauma type, root development stage, and preoperative sinus tract significantly influenced outcome distribution (<i>P</i><0.05). Avulsion and intrusion injuries exhibited higher failure rates in the RET efficacy analysis, at 27.9% (12/43) and 3/11 respectively. Teeth at Nolla stage 9 accounted for the largest proportion [48.5%, (63/130)], with a success rate of 88.9% (56/63). Teeth with a preoperative sinus tract had a significantly higher failure rate (8/14) than those without [13.8% (16/116)] (<i>P</i>=0.014). Multivariable logistic regression analysis identified avulsion as a risk factor for treatment failure compared with fracture injury (<i>OR</i>=3.58, 95%<i>CI</i>: 1.05-12.23, <i>P</i>=0.042). Kaplan-Meier survival analysis for maintaining\"favorable healing\"status revealed significant differences among the three trauma groups (<i>P</i>=0.002), the avulsion group showed the poorest maintenance capacity, the fracture group the best. <b>Conclusions:</b> RET is an effective therapeutic approach for traumatized immature permanent teeth with pulp necrosis. Treatment outcomes are influenced by multiple factors, including trauma type and preoperative infection status. Comprehensive clinical evaluation is necessary for individualized treatment planning. Further research is needed to optimize treatment strategies.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"633-639"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Experimental study on the effects of 810-nm diode low-level laser on oxidative stress and wound healing].","authors":"J Q Zhao, C Y Peng, Y Y Kang, Y Zhang","doi":"10.3760/cma.j.cn112144-20260130-00064","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260130-00064","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the mechanism by which an 810-nm diode low-level laser (LLL) promotes angiogenesis through activation of the nuclear factor erythroid 2-related factor 2/heme oxygenase-1 (NRF2-HO-1) signaling pathway, and to provide a theoretical basis for the repair of acute soft-tissue injury. &lt;b&gt;Methods:&lt;/b&gt; 1. &lt;i&gt;In vitro&lt;/i&gt; experiments, oxidative stress injury in human umbilical vein endothelial cells (HUVECs)was induced by treatment with 100 μmol/L H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; for 12 h. The cells were divided into a control group, an H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; group, and low-level laser intervention groups. The intervention groups received 810-nm diode laser irradiation at energy densities of 2 J/cm&lt;sup&gt;2&lt;/sup&gt; (E1 group), 4 J/cm&lt;sup&gt;2&lt;/sup&gt; (E2 group), and 8 J/cm&lt;sup&gt;2&lt;/sup&gt; (E3 group). Cell proliferation was assessed using the CCK-8 assay. Cell migration was evaluated using wound-healing and Transwell assays. Tube formation on Matrigel was performed to assess in vitro capillary-like structure formation. Intracellular reactive oxygen species (ROS) levels were measured using the 2', 7'-dichlorodihydrofluorescein diacetate (DCFH-DA) probe, and mitochondrial membrane potential was detected using the JC-1 probe. Immunofluorescence staining was performed to detect NRF2 nuclear translocation and HO-1 expression. 2. &lt;i&gt;In vivo&lt;/i&gt; experiments, SPF male Sprague-Dawley rats (200-250 g) were used to establish a full-thickness skin wound model. The rats were randomly divided into a control group and a LLL therapy (LLLT) group. The LLLT group received 810-nm laser irradiation at an energy density of 40 J/cm&lt;sup&gt;2&lt;/sup&gt; on the wound area, whereas the control group received no laser treatment. Wound area and healing rate were measured using ImageJ software. Histological changes were observed by HE and Masson staining, and angiogenesis was evaluated by CD31 immunofluorescence staining. &lt;b&gt;Results:&lt;/b&gt; Compared with the control group, H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; treatment significantly decreased the proliferative activity of HUVECs, increased intracellular ROS levels, and reduced mitochondrial membrane potential. After LLL irradiation, cell proliferation increased in all treatment groups compared with the H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; group. In particular, the E2 group (4 J/cm&lt;sup&gt;2&lt;/sup&gt;) showed optical density values of 1.24±0.11, 1.43±0.06, and 1.83±0.14 at 24, 48, and 72 h, respectively, which were higher than those in the H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The wound-healing assay showed significant differences in migration rates among groups (&lt;i&gt;P&lt;/i&gt;&lt;0.001), with the E2 group showing a migration rate of (%56.07±5.61%), compared with (24.83%±4.31%) in the H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; group. Transwell assay results also showed significant differences in the number of migrated cells among groups (&lt;i&gt;P&lt;/i&gt;&lt;0.001); the E2 group had 74.62±5.98 migrated cells, which was higher than the 20.21±6.55 cells observed in the H&lt;sub&gt;2&lt;","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"678-688"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Twenty-one year follow-up of comprehensive treatments for immature permanent teeth after trauma: a case report].","authors":"L Li, G A Sheng, L P Sheng","doi":"10.3760/cma.j.cn112144-20260119-00032","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260119-00032","url":null,"abstract":"","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 5","pages":"706-710"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Imbalance and reconstruction of periodontal homeostasis: new perspectives on the pathogenesis, prevention and treatment of periodontitis].","authors":"H Y Wang, C Li, Y P Pan","doi":"10.3760/cma.j.cn112144-20251209-00499","DOIUrl":"10.3760/cma.j.cn112144-20251209-00499","url":null,"abstract":"<p><p>Periodontal homeostasis is a dynamic equilibrium based on healthy periodontal structures, a relatively stable oral microbiome, appropriately regulated host immunity, coordinated cellular metabolism, and a functional dentition with normal occlusion. This review aims to systematically elucidate the key mechanisms underlying the maintenance and disruption of periodontal homeostasis. The dysregulation of microbiota and excessive immune activation mutually reinforce each other, serving as the core driving forces for the occurrence and progression of periodontitis. On this basis, a treatment approach oriented toward \"re-establishing periodontal homeostasis\" is proposed. Based on microbiota remodeling and structural reconstruction, combined with host immune regulation and immunometabolic intervention, emphasizing systemic risk factor management and functional dentition reconstruction, we aim to establish a personalized, precise, and sustainable new model for periodontal prevention and treatment.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 4","pages":"445-451"},"PeriodicalIF":0.0,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}