中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240610-00259
S Z Shen, Z X Gao, Q Liu, S F Lou, Z X Zhao
{"title":"[Experience in the construction of protective facilities for radiation diagnosis and treatment rooms in medical institutions].","authors":"S Z Shen, Z X Gao, Q Liu, S F Lou, Z X Zhao","doi":"10.3760/cma.j.cn121094-20240610-00259","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240610-00259","url":null,"abstract":"<p><p>With the rapid development of radiological diagnosis and treatment technology, the construction of radiation diagnosis and treatment machine room and radiation safety management have become an important part of the daily management of hospitals. Due to the large number of laws and regulations involved, some hospitals still have problems such as imperfect construction of management systems, and insufficient professional competence of personnel, which leads to a lack of experience in the construction of radiation diagnosis and treatment room and radiation safety management in hospitals. This paper analyzed the practical experience of construction of radiological diagnosis and treatment machine room and radiation safety management. This paper analyzed the experience in constructing protective facilities for radiation diagnosis and treatment rooms in a medical institution, and provides the basis and reference for relevant units in room construction and radiation safety management.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"312-314"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240330-00132
H D Zhang, F H Zeng, H Wang
{"title":"[Study on comorbidity between post-traumatic stress disorder and depressive symptoms in firefighters].","authors":"H D Zhang, F H Zeng, H Wang","doi":"10.3760/cma.j.cn121094-20240330-00132","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240330-00132","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the epidemiological characteristics of comorbidity of post-traumatic stress disorder and depression symptoms among active firefighters, and explore its influencing factors. <b>Methods:</b> In November 2021, a cross-sectional study was conducted using a combination of convenience sampling and cluster sampling. Active firefighters were selected as the research subjects for a questionnaire survey. 1100 questionnaires were distributed, 1032 were collected, and 1021 were valid, with an effective response rate of 98.93%. The PTSD prevalence and characteristics of firefighters were assessed by using the PTSD Checklist Civilian Version (PCL-C) . The degree of depression was assessed by the Patient Health Questionnaire (PHQ-9) . The coping style was assessed by the Trait Coping Style Questionnaire, and the Social Support Rate Scale was used to investigate the degree of social support. Combined with the general information, the influencing factors of comorbidity of PTSD and symptoms of depression in firefighters were analyzed with binary logistic regression based on single factor analysis. <b>Results:</b> Among 1021 firefighters, 379 had a PHQ-9 score of ≥5, and the prevalence rate of depression was 37.1% (379/1 021) . The prevalence rate of PTSD is 4.6% for 47 individuals with a total PCL-C score of ≥38, and the comorbidity rate of depressive symptoms among PTSD patients is 100%. Logistic regression analysis showed that injuries in the past six months, average/poor self-rated health status, and negative coping were all promoting factors for both the simple depression symptom group and the comorbidity group, while social support was the hindering factor (<i>P</i><0.05) . Two sets of <i>OR</i> values show that negative coping and social support have roughly the same degree of impact in both groups. The <i>OR</i> (95%<i>CI</i>) values of the two factors of being injured in the past six months and self-rated as average/poor health status have significantly increased in the comorbidity group. The <i>OR</i> (95%<i>CI</i>) values of being injured in the past six months has increased from 2.20 (1.24, 3.93) in the simple depression symptom group to 3.44 (1.30, 9.09) in the comorbidity group, and that of the self-rated as average and poor health status has increased from 4.91 (3.01, 8.00) to 6.56 (1.97, 21.87) and from 7.96 (2.25, 28.25) to 19.17 (4.75, 77.31) separately (<i>P</i><0.05) . <b>Conclusion:</b> The results indicate that firefighters with PTSD generally have comorbidity with depressive symptoms. The common influencing factor of being injured in the past six months is consistent with the pattern of PTSD symptoms triggered by depressive symptoms.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"288-293"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240408-00152
R S Peng, L L Xu, F Wang, Y J Su, Y H Ji, Y Zheng, F Ji
{"title":"[Investigation and influencing factors of hearing loss among workers in a gas production plant].","authors":"R S Peng, L L Xu, F Wang, Y J Su, Y H Ji, Y Zheng, F Ji","doi":"10.3760/cma.j.cn121094-20240408-00152","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240408-00152","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the present situation and influencing factors of hearing loss among noise exposed workers in a gas production plant, and to provide basis and guidance for enterprises to prevent hearing loss. <b>Methods:</b> In November 2023, a cross-sectional survey was conducted among personnel exposed to noise in a gas production plant. A total of 380 questionnaires were collected, among which 319 were valid resulting in an effective recovery rate of 83.9%. Ultimately, 292 were included in the study. The questionnaire covered demographic characteristics, work conditions, behavioral and lifestyle habits, hearing loss, and medical history. The noise exposure levels of the research subjects were determined based on the occupational disease hazard factor detection reports provided by the gas production plant for 2022 and 2023. Whether hearing loss occurred was determined based on the pure tone audiometry results from the occupational health examination. Chi-square tests were used to analyze the influence of demographic characteristics, work conditions, and behavioral and lifestyle habits on hearing loss. A multivariate logistic regression model was used to analyze the relationship between hearing loss and related influencing factors. <b>Results:</b> Among the noise-exposed workers in the gas production plant, the incidence of high-frequency hearing loss was 14.4% (42/292) . The rate of hearing loss among men was higher than that among women (<i>P</i>=0.010) , and the rate of hearing loss among those with a history of smoking was higher than that among those who had never smoked (<i>P</i>=0.015) . <b>Conclusion:</b> Gas production enterprises should prioritize targeted interventions for workers with prolonged employment histories and smoking habits. Training programs should be implemented to cultivate proper ear protection practices, enhance knowledge of hearing conservation, and promote healthier lifestyle behaviors among employees.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"305-308"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240118-00026
F Zhou, L L Zeng, J Zhou, L B Ke, H B Chen, S P Lin
{"title":"[Evaluation of survival quality of the occupationally exposed population of subway microwave based on SF-36 scale].","authors":"F Zhou, L L Zeng, J Zhou, L B Ke, H B Chen, S P Lin","doi":"10.3760/cma.j.cn121094-20240118-00026","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240118-00026","url":null,"abstract":"<p><p><b>Objective:</b> The SF-36 Scale was utilized to compare the differences in the dimensions of survival quality between subway microwave contact personnel and administrative personnel to provide a scientific basis for improving the quality of life of microwave contact personnel. <b>Methods:</b> In October 2023, 264 occupational personnel exposed to microwaves were selected as the microwave exposure group, and 104 administrative personnel not exposed to microwaves in a railroad enterprise were selected as the administrative control group. The self-administered basic data questionnaire and SF-36 Scale were applied to investigate the basic conditions, daily behaviors and survival quality of the research objects. And the microwave exposure doses of each post were measured. The differences in basic conditions, daily behaviors and survival quality of the microwave exposure group and the administrative control group were analyzed. And logistic regression was used to analyze the influencing factors of survival quality in the microwave exposure group. <b>Results:</b> There were significant differences in gender, age, marital status, smoking status and sleep status between the microwave exposure group and the administrative control group (<i>P</i><0.05) . The microwave exposure group had lower scores than the administrative control group in the six dimensions of role physical, body pain, general health, vitality, social function, mental health and SF-36 average total score, and had higher score in reported health transition (<i>P</i><0.05) . The logistic regression analysis showed that the probability of low total SF-36 score in microwave exposure group with bachelor's degree or above was 0.46 times that of junior college degree (95%<i>CI</i>: 0.24-0.90, <i>P</i>=0.023) . The probability of low total SF-36 score in microwave exposure group with exercised 4 or more times per week was 4.27 times that of those who never or occasionally exercised (95%<i>CI</i>: 1.41-13.00, <i>P</i>=0.010) . The probabilities of low total SF-36 score in microwave exposure group with sleep light and dream, wake up in the middle night and hard to fall asleep were 11.04 and 7.38 times higher than those without sleep disturbance (95% <i>CI</i>: 3.35-36.32, <i>P</i><0.001; 95% <i>CI</i>: 1.42-38.50, <i>P</i>=0.018) . The probability of low total SF-36 score in microwave exposure group with daily dose of 1.74 μW·h/cm(2) was 1.75 times that of the daily dose of 1.02 μW·h/cm(2) (95%<i>CI</i>: 1.08-3.82, <i>P</i>=0.008) . <b>Conclusion:</b> The education level, physical exercise, sleep status and microwave exposure dose are important factors affecting the survival quality of microwave exposed personnel. Occupational health education and behavioral life intervention should be strengthened to improve their survival quality.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"264-268"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240221-00061
Q H Du, Y F Wu, J B Zhang, Y L Kong
{"title":"[Analysis and diagnostic exploration of a dimethylacetamide poisoning incident in a small and micro enterprise].","authors":"Q H Du, Y F Wu, J B Zhang, Y L Kong","doi":"10.3760/cma.j.cn121094-20240221-00061","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240221-00061","url":null,"abstract":"<p><p>In this paper, the causes of dimethylacetamide poisoning in a small and micro enterprise were analyzed through on-site occupational health investigation, clinical data summary of poisoned patients and occupational hazard factors detection results. The incident was a group poisoning incident caused by exposure to dimethylacetamide, resulting in different degrees of toxic liver disease in 6 workers. Although the concentration of dimethylacetamide in the air in the workplace was excessive, percutaneous absorption may be the main cause of poisoning. The characteristics of percutaneous absorption of dimethylacetamide need to be paid great attention to, which can be used for reference to prevent similar incidents in the future.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"294-296"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240402-00137
S Y Yang, Y D Zhang, Y J Xie, H Y Yin, P Gu, D M Wang, W H Chen, J X Ma
{"title":"[Smad3 signaling pathway promotes silica-induced epithelial-mesenchymal transition].","authors":"S Y Yang, Y D Zhang, Y J Xie, H Y Yin, P Gu, D M Wang, W H Chen, J X Ma","doi":"10.3760/cma.j.cn121094-20240402-00137","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240402-00137","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the role of the Smad3 signaling pathway in the process of silica-induced epithelial-mesenchymal transition (EMT) . <b>Methods:</b> In September 2022, lung epithelial cells (BEAS-2B) were exposed to different concentrations of silica suspension (0, 50, 100, and 150 μg/ml) for 6 and 12 hours. Additionally, SIS3, a specific inhibitor of phosphorylated Smad3 (p-Smad3) , was utilized to establish the p-Smad3 inhibition model. The cells were divided into four groups: blank control gruop, silica group, SIS3 intervention group, and SIS3 +silica group. Cell morphology was observed using an inverted fluorescence microscope, while cell viability was assessed using a Cell Counting Kit-8 (CCK-8) . The mRNA and protein expression levels of E-cadherin (E-Cad) , N-cadherin (N-Cad) , Vimentin, Smad3, and p-Smad3 were analyzed by Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting, respectively. Differences between two groups were compared using Student's t-test, and multiple group comparisons were analyzed using a one-way analysis of variance with the Student-Newman-Keuls test. <b>Results:</b> Compared with the blank control group, the morphology of BEAS-2B cells shifted from epithelial to mesenchymal cell-like following silica exposure, and the cell viability of BEAS-2B cells declined after exposure to 150 μg/ml silica for 6 and 12 hours. Furthermore, silica exposure led to significant reductions in mRNA and protein expression levels of the epithelial cellular marker (E-Cad) in BEAS-2B cells, accompanied by increased expressions of interstitial cellular markers (N-Cad and Vimentin) . Importantly, the level of p-Smad3/Smad3 expression levels was also elevated in silica-treated cells (<i>P</i><0.05) . Compared to the blank control group, the level of p-Smad3/Smad3 expression levels was significantty reduced. Moreover, compared to the silica group, the protein expression levels of N-Cad and Vimentin in the cell of the SIS3+silica group were significantly reduced, while the E-Cad expression was increased (<i>P</i><0.05) . <b>Conclusion:</b> Silica exposure can prmote the epithelial mesenchymaol transformotion process by activating smod3 signa ling pathuay, and in hibiting smad3 signa ling pathuay can effctively alleviate the occurrence of epithelial mesenchymal transformation process.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"241-246"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240703-00296
S W Zhong, N Jia, X Sun, M B Zhang, Q Xu, H D Zhang, R J Ling, Y M Liu, G Li, Y Yin, H Shao, J Li, H D Zhang, B Qiu, D Y Wang, Q Zeng, R G Wang, Y Ye, B Xiao, H Zou, J C Chen, D X Li, Y Q Liu, Q H Shi, J X Liu, E F Jiang, J Qi, L Y Mei, X F Zhao, M M Yang, X W Guo, Z Wang, Z X Wang
{"title":"[Structural equation analysis and modeling of upper limb WMSDs and their adverse ergonomic factors].","authors":"S W Zhong, N Jia, X Sun, M B Zhang, Q Xu, H D Zhang, R J Ling, Y M Liu, G Li, Y Yin, H Shao, J Li, H D Zhang, B Qiu, D Y Wang, Q Zeng, R G Wang, Y Ye, B Xiao, H Zou, J C Chen, D X Li, Y Q Liu, Q H Shi, J X Liu, E F Jiang, J Qi, L Y Mei, X F Zhao, M M Yang, X W Guo, Z Wang, Z X Wang","doi":"10.3760/cma.j.cn121094-20240703-00296","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240703-00296","url":null,"abstract":"<p><p><b>Objective:</b> To explore the structural relationship between WMSDs in the upper limbs and various risk factors in the occupational population in China, based on a large sample epidemiological survey and structural equation analysis, and to establish a structural equation model, so as to lay a foundation for the prevention and control of such diseases. <b>Methods:</b> The Chinese version of the Musculoskeletal Disorders Electronic Questionnaire was used to conduct a nationwide survey on the prevalence of WMSDs in the upper extremity. Six factors related to WMSDs in the upper extremity were extracted by the classification standard of adverse ergonomic factors and their source and confirmatory factor analysis, including work organization, work type, upper extremity work posture, individual factors, upper extremity fatigue and upper extremity WMSDs. The structural equation analysis was carried out and the structural equation model was established. <b>Results:</b> The incidence of WMSDs and fatigue in the upper limbs was 24.44% and 43.76%, respectively. The adjusted structural equation model fitting indicators were generally up to the standard (GFI=1.000, AGFI=1.000, RMSEA=0.043, NFI=0.808, TLI=0.784) . The four exogenous latent variables of work organization, work type, upper limb work posture and individual factors were correlated. There was a strong positive correlation between job type and upper limb work posture (<i>r</i>=0.865) , a moderate positive correlation between work organization and job type and upper limb work posture (<i>r</i>=0.570, 0.490) , and a weak negative correlation between individual factors and the other three exogenous latent variables. Upper limb work posture and individual factors had direct effects on upper limb WMSDs, and the effect coefficients were 0.10 and 0.06, respectively. Upper limb fatigue played a mediating role between work organization, work type, upper limb work posture and upper limb WMSDs. The effect coefficient was 0.46, and the composition ratios of indirect effects were 100.0%, 100.0%, and 38.3%, respectively. The direct path effect of upper limb work posture, individual factors and upper limb WMSDs was weaker than the mediating path through upper limb fatigue. <b>Conclusion:</b> When carrying out the prevention and control of upper limbWMSDs, it is necessary to comprehensively consider the pathogenesis path of upper limb muscle fatigue and upper limb WMSDs caused by work organization, work type, and upper limb work posture, so as to provide theoretical reference for improving the prevention and control level of such diseases.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"254-263"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240120-00030
R Hai, X P Gao, L J Xu, X Q Liang, M T Liu, L Ning
{"title":"[Effects of combined exposure to dust and noise on blood pressure and electrocardiogram of mechanical manufacturing workers].","authors":"R Hai, X P Gao, L J Xu, X Q Liang, M T Liu, L Ning","doi":"10.3760/cma.j.cn121094-20240120-00030","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240120-00030","url":null,"abstract":"<p><p><b>Objective:</b> To explore the impact of noise and dust exposure in the mechanical manufacturing industry on the risk of hypertension and abnormal electrocardiogram in workers, and their combined effects, in order to provide support for the prevention and treatment of occupational related diseases among workers. <b>Methods:</b> In January 2024, A convenience sampling method was used to study 2802 on-the-job workers who underwent occupational health check-ups from January 2023 to December 2023 at a machinery manufacturing enterprise in Baotou, Inner Mongolia. Blood pressure and electrocardiogram results were analyzed in the noise group, dust group, dust noise group and control group according to the exposure factors. For count data, the chi-square test was employed to analyze differences among groups. Additionally, a binary logistic regression model was utilized to assess the impact of dust and noise exposure on the prevalence of hypertension and electrocardiogram abnormalities. <b>Results:</b> The stratified analysis results showed that the differences in hypertension prevalence among the four groups were statistically significant (<i>P</i><0.001) in males, age groups >30-40 years, >40-50 years, >50 years, different exposure durations, and different enterprise sizes. For ECG abnormalities, significant differences were observed among the four groups (<i>P</i><0.001) in males, the age group >30-40 years, different enterprise sizes, and those with exposure durations ≤15 years. The trend test for hypertension prevalence across different age groups revealed that as age increased, the prevalence of hypertension showed an upward trend in the noise-exposed group, dust-exposed group, and combined dust-noise-exposed group (<i>χ</i>(2)=10.76, 4.25, 6.60, <i>P</i><0.001, 0.039, 0.010) . Binary regression model analyses revealed that the the risk of hypertension in the noise group, dust group and dust noise group was 2.63 times (<i>OR</i>=2.63, 95%<i>CI</i>: 1.89~3.67, <i>P</i><0.001) , 2.36 times (<i>OR</i>=2.36, 95%<i>CI</i>: 1.76~3.16, <i>P</i><0.001) and 2.69 times (<i>OR</i>=2.69, 95%<i>CI</i>: 2.14~3.38, <i>P</i><0.001) . Using ECG abnormalities as the dependent variable and incorporating the statistically significant variables from Table 1 as independent variables into the binary logistic regression model, the results showed no statistically significant differences in the risk of ECG abnormalities in the dust-exposed, noise-exposed, and combined dust-noise-exposed groups compared to the control group (<i>P</i>> 0.05) . <b>Conclusion:</b> Combined exposure to dust and noise increases the risk of hypertension in workers and has a combined effect.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"275-280"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20240605-00253
H Xing, Turepu Aisanjiang, Y J Cheng, P Dong, S Q Ma, J X Xu, H Dou, X R Ai
{"title":"[Dual-energy spectral CT quantitative indicators assist in the risk prediction of pneumoconiosis].","authors":"H Xing, Turepu Aisanjiang, Y J Cheng, P Dong, S Q Ma, J X Xu, H Dou, X R Ai","doi":"10.3760/cma.j.cn121094-20240605-00253","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240605-00253","url":null,"abstract":"<p><p><b>Objective:</b> To explore the quantitative indexes of dual energy spectrum CT and related clinical data to establish a predictive model for predicting pneumoconiosis. <b>Methods:</b> In April 2024, the information of 203 pneumoconiosis patients diagnosed by the occupational disease appraisal expert group in the Third People's Hospital of Xinjiang Uygur Autonomous Region (Occupational Disease Hospital of Xinjiang Autonomous Region) from January 2022 to December 2023 was retrospectively analyzed. Another 207 non-pneumoconiosis patients with dust exposure history were selected as control group. The measurement data between the two groups were compared using T test or Wilcoxon in dependent quality test, count date asing chi-square or Fishers test, the energy spectrum related indicators and clinical indicators of the patients were compared between groups, and potential factors for diagnosis of pneumoconiosis were screened through univariate analysis, and independent risk factors were further determined by multivariate logistic regression. Based on the results of regression analysis, the machine learning model was constructed, and the reciver operating characteristic curve (ROC) was drawn to evaluate the efficiency of the model, and the Area under cruve (AUC) value, sensitivity and specificity were calculated. <b>Results:</b> Smoking, lung tissue mass, silicon dioxide (SiO(2)) equivalent total mass and SiO(2) equivalent concentration were the risk factors for pneumoconiosis (<i>P</i><0.05) . Multivariate logistic regression analysis showed that smoking, lung tissue mass, total lung SiO(2) equivalent total volume and total lung SiO(2) equivalent total mass were independent predicators of the diagnosis of pneumoconiosis (<i>OR</i>=0.53, 0.99, 1.13, 0.85, <i>P</i><0.05) . Logistic regression machine learning was used to establish a predictive model, and the training set AUC was 0.74, and the verification set AUC was 0.72, indicating that the model had good accuracy and certain ability to diagnose pneumoconiosis. <b>Conclusion:</b> The machine learning prediction model established by the quantitative analysis index of dual energy spectrum CT and clinical related indexes has a good diagnostic performance for the diagnosis of pneumoconiosis.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"297-301"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-04-20DOI: 10.3760/cma.j.cn121094-20231201-00137
Y M Zheng, S Q Li, W Liu, L Guan
{"title":"[Relevant regulations on occupational exposure protection of anti-neoplastic drugs in China].","authors":"Y M Zheng, S Q Li, W Liu, L Guan","doi":"10.3760/cma.j.cn121094-20231201-00137","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20231201-00137","url":null,"abstract":"<p><p>Antineoplastic drugs have clear health hazards to the human body. In recent years, the scale of use of antineoplastic drugs had continued to expand, and the occupational exposure risk of medical personnel had also increased, which had attracted widespread attention. Taking effective measures to prevent occupational exposure can protect the health of medical personnel. This article reviewed the laws, regulations, guidelines, and industry guidance documents on occupational exposure prevention and control of antineoplastic drugs issued by relevant departments and associations in China. It summarized the scientific management experience of antineoplastic drugs in China, with the aim of reducing the occupational exposure risk of antineoplastic drugs in the future, and assisting the healthy development of China's medical and health industry.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 4","pages":"309-312"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}