中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240701-00291
S Zhou, Z X Wang, R J Ling, Q Xu, H D Zhang, Y M Liu, G Li, Y Yin, H Shao, J Li, H D Zhang, B Qiu, D Y Wang, Q Zeng, Y Ye, B Xiao, H Zou, J C Chen, D X Li, Y Q Liu, J X Liu, E F Jiang, J Qi, L Y Mei, X F Zhao, M M Yang, N Jia
{"title":"[Structural equation analysis of the incidence of shoulder WMSDs and individual and work-related factors].","authors":"S Zhou, Z X Wang, R J Ling, Q Xu, H D Zhang, Y M Liu, G Li, Y Yin, H Shao, J Li, H D Zhang, B Qiu, D Y Wang, Q Zeng, Y Ye, B Xiao, H Zou, J C Chen, D X Li, Y Q Liu, J X Liu, E F Jiang, J Qi, L Y Mei, X F Zhao, M M Yang, N Jia","doi":"10.3760/cma.j.cn121094-20240701-00291","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240701-00291","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the incidence of shoulder work-related musculoskeletal disorders (WMSDs) among occupational population in China, and to explore their intrinsic association with personal and work-related factors. <b>Methods:</b> In April 2024, 73497 valid questionnaires of the Chinese version of the Musculoskeletal Disorders Electronic Questionnaire were retrospectively analyzed from June 2018 to December 2023 in 22 provinces and 29 key industries in China, and the general information, occurrence of WMSDs and related risk factors of key occupational populations in different regions in China were collected. By using Chi-square test and confirmatory factor analysis, the relationship between shoulder fatigue and pain in key occupational groups and individual factors, work type, work posture and work organization was discussed, and the internal relationship was analyzed based on structural equation model. <b>Results:</b> Higher incidence of shoulder fatigue and pain were associated with female, lack of physical exercise, uncomfortable working posture and neck leaning forward (<i>P</i><0.05). Structural equation model analysis showed that work type, work posture and work organization were strongly correlated (<i>r</i>=0.58, 0.55). Work organization and work type were strongly correlated with shoulder fatigue (<i>r</i>=0.65) and moderately correlated with shoulder fatigue (<i>r</i>=0.21). Shoulder fatigue was moderately associated with shoulder pain (<i>r</i>=0.40). Individual factors, work type, work posture and shoulder fatigue could directly affect shoulder pain (<i>OR</i>=0.07, -0.09, 0.17 and 0.40), and work type and work posture could also indirectly affect shoulder pain through shoulder fatigue (<i>OR</i>=0.08, 0.03). Work organization only indirectly affected shoulder pain through shoulder fatigue (<i>OR</i>=0.26) . <b>Conclusion:</b> The main influencing factor of shoulder pain is shoulder fatigue, followed by work posture and individual factors. Structural equation model can better reflect the complex relationship between work type, work posture and work organization and shoulder WMSDs. Improving work posture and work organization may be an effective way to control the influence of shoulder fatigue on shoulder pain.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"91-100"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240423-00183
Z H Peng, P X Chen, H Zhang, F Yang, Y Yin, N Jia, Z Wang, Z X Wang
{"title":"[Standard interpretation of the Ergonomic Guidelines for the Prevention of Work-related Musculoskeletal Disorders Part 3 in Shipbuilding Manufacturing Work].","authors":"Z H Peng, P X Chen, H Zhang, F Yang, Y Yin, N Jia, Z Wang, Z X Wang","doi":"10.3760/cma.j.cn121094-20240423-00183","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240423-00183","url":null,"abstract":"<p><p>The \"Guidelines for the Ergonomic Prevention of Work-related Musculoskeletal Disorders Part 3 in Shipbuilding Operations\" (T/WSJD 14.3-2024) was published and implemented in March 2024, providing a basis for scientific prevention and control of musculoskeletal disorders in shipbuilding operations. In this paper, the background, formulation process, basis and main content of the standard project are interpreted and analyzed, so as to help relevant practitioners and managers more fully understand and implement the ergonomic program proposed by the standard, and provide scientific and accurate technical support for enterprises.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"146-149"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240322-00112
X Wu, S Q Lan, E L Gong, H Z Ye, P Lan
{"title":"[Study on the application of immature platelet and thromboelastography in assessing the risk of hemorrhage after blood-poisonous snake bite].","authors":"X Wu, S Q Lan, E L Gong, H Z Ye, P Lan","doi":"10.3760/cma.j.cn121094-20240322-00112","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240322-00112","url":null,"abstract":"<p><p><b>Objective:</b> To explore the value of immature platelets and thromboelastography (TEG) in evaluating bleeding tendency in patients bitten by blood venomous snakes. <b>Methods:</b> In December 2023, a bleeding scoring system was used to grade the bleeding score and degree of bleeding in 147 patients with blood venomous snake bites. Immature platelets and TEG were also tested to analyze the correlation between the bleeding degree of patients and indicators such as TEG, immature platelet ratio (IPF), and absolute value of immature platelets (A-IPF). The measurement data were represented by Mean±SD, and ANOVA was used for comparison among groups. Statistical data were analyzed using <i>χ</i>(2) test. Spearman correlation was used to analyze the correlation between bleeding degree and the platelet count (PLT), immature platelet and TEG. Pearson linear correlation was used to analyze the correlation of PLT, immature platelets and TEG. The indexes of immature platelets and TEG were analyzed by receiver operating characteristic curve. <b>Results:</b> The 147 patients were graded for bleeding severity based on their bleeding scores, and divided into mild (22 cases), moderate (119 cases), and severe groups (6 cases), and the clinical data such as age, gender and the time from bite to visit were compared among the three groups. The differences were not statistically significant (<i>P</i>>0.05). The coagulation reaction time (R), clot formation time (K), and immature platelet parameters (IPF, A-IPF) in TEG parameters increased with the degree of bleeding. PLT decreased with the degree of bleeding, and the difference was statistically significant (<i>P</i><0.05). Blood venomous snake bite patients have a negative correlation between PLT and IPF (<i>r</i>=-0.301, <i>P</i>=0.012), but no correlation with A-IPF (<i>r</i>=0.072, <i>P</i>=0.461) ; PLT was positively correlated with coagulation Angle (αAngle) and maximum thrombus amplitude (MA) of TEG (<i>r</i>=0.220、0.243, <i>P</i>=0.028、0.015), but negatively correlated with R value and K value (<i>r</i>=-0.368、-0.362, <i>P</i><0.001). IPF is positively correlated with R and K values (<i>r</i>=303、271, <i>P</i>=0.0020、0.035) ; IPF is not correlated with MA value and Angle angle, while A-IPF is positively correlated with R value (<i>r</i>=0.162, <i>P</i><0.001). The degree of bleeding in patients is positively correlated with R value (<i>r</i>=0.237, <i>P</i><0.001), but not with K value, MA value, and Angle angle (<i>P</i>>0.05) ; The degree of bleeding in patients is correlated with PLT (<i>r</i>=-0.411, <i>P</i><0.001). The ROC curve analysis results show that the R value, K value, and MA value are effective in evaluating the bleeding risk of blood venomous snake bites in patients, and the PLT combined with A-IPF has the best efficacy in evaluating the bleeding risk of blood venomous snake bites in patients. <b>Conclusion:</b> The combination of PLT and A-IPF, TEG's R value, K value, MA value indicato","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"134-138"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240313-00094
Y Q Lin, Y Zhang, X Y Chen, W K Li, Y J Niu, X F Wang, N Liu, G Li
{"title":"[Nano-ITO induce pulmonary alveolar proteinosis through oxidative stress and activation of NF-κB/Nrf2 signaling pathway].","authors":"Y Q Lin, Y Zhang, X Y Chen, W K Li, Y J Niu, X F Wang, N Liu, G Li","doi":"10.3760/cma.j.cn121094-20240313-00094","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240313-00094","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the role of the nuclear factor-kappa B (NF-κB) /nuclear factor E2 related factor 2 (Nrf2) pathway in the occurrence of lung tissue in the pulmonary alveolar proteinosis (PAP) model of rats induced by indium tin oxide nanoprticles (Nano-ITO) . <b>Methods:</b> In October 2019, 120 SD rats were divided into 3, 7, 14, 28, 56, and 84 day Nano ITO exposure groups and corresponding time point control groups, with 10 rats in each group; the exposure group was treated with 6 mg/kg·bw Nano-ITO via non exposed tracheal injection, twice a week. Time-course studies were performed to examine the pulmonary toxicity induced by Nano-ITO. At the end of the experiment, cytokines levels and oxidative stress were analyzed in the bronchoalveolar lavaged fluid (BALF). Rat lung tissues were also harvested for staining with HE, PAS, Masson, and Oil Red O. Ultrastructure of lung tissue cells was observed by transmission electron microscope. The localization and expression of NF-κB p65, IκB-α, IKK-β, Nrf2, NQO1, HO-1 were observed by immunohistochemistry, Western blot and real-time fluorescent quantitative PCR. The comparison between the two groups was analyzed by independent sample T test, and the comparison between the multiple groups was analyzed by one-way ANOVA. <b>Results:</b> Nano-ITO intratracheal instillation caused pulmonary toxicity by inducing acute inflammation, granuloma (nodule) formation, and alveolar proteinosis. ELISA analysis showed that, compared with the corresponding time points control groups, the levels of superoxide dismutase (SOD), total antioxidant capacity (T-AOC), malondialdehyde (MDA), interleukin (IL) -1β, IL-6, tumor necrosis factor alpha (TNF-α), IL-10, total protein (TP), and lactate dehydrogenase (LDH) in BALF of rats exposed to Nano ITO were all increased (<i>P</i><0.05) ; The protein expression of Nrf2 and NF-κB p65 was upregulated in rat lung tissue, while the protein expression of KK-β was increased (<i>P</i><0.01). Nrf2 and its downstream proteins NQO1 and HO-1 were highly expressed in Nano-ITO-induced PAP rat. <b>Conclusion:</b> NF-κB/Nrf2 signal pathway is involved in the process of Nano-ITO induced pulmonary alveolar proteinosis in rats.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"81-90"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240122-00033
M L Bi, X Y Cui, X F Wang, X X Peng, J Li, H N Wang, X S Wang, X W Ding
{"title":"[The correlation between WMSDs and thyroid indicators in male large-scale mechanical maintenance workers].","authors":"M L Bi, X Y Cui, X F Wang, X X Peng, J Li, H N Wang, X S Wang, X W Ding","doi":"10.3760/cma.j.cn121094-20240122-00033","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240122-00033","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the status of work-related musculoskeletal disorders (WMSDs) in male large-scale mechanical maintenance workers, and to explore the relationship between WMSDs and thyroid indexes. <b>Methods:</b> From April to July 2022, male front-line maintenance workers in a large-scale mechanical maintenance enterprise who participated in occupational health examination were selected as the study subjects (<i>n</i>=2036). The occurrence of WMSDs was investigated by questionnaire. The levels of triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) in serum were detected. <i>χ</i>(2) test, <i>t</i>-test and Mann-Whitney U test were used to detect thyroid diseases and hormone levels of workers in WMSDs group and non-WMSDs group, and binary logistic regression model was used to analyze the relationship between thyroid disease, T3, T4, TSH and WMSDs. <b>Results:</b> The incidence of WMSDs among the male large-scale mechanical maintenance workers was 73.18% (1490/2036). The rate of thyroid disease in WMSDs group was higher than that in non-WMSDs group [8.26% (123/1490) vs. 4.95% (27/546), χ(2)=6.42, <i>P</i>=0.011], and the TSH value was lower than that in non-WMSDs group[1.66 (1.23, 2.26) μIU/ml vs. 1.75 (1.30, 2.42) μIU/ml, <i>Z</i>=-2.40, <i>P</i>=0.019]. There were no significant differences in the levels of T3, T4 and abnormal levels of 3 hormones between the two groups (<i>P</i>>0.05). After accounting for individual and occupational factors, workers with thyroid disease had an increased risk of WMSDs (<i>OR</i>=1.656, 95%<i>CI</i>: 1.072-2.559, <i>P</i>=0.023), while workers with increased TSH had a decreased risk of WMSDs (<i>OR</i>=0.897, 95% <i>CI</i>: 0.823-0.977, <i>P</i>=0.013) . <b>Conclusion:</b> The incidence of WMSDs in male workers of large-scale mechanical maintenance is high, and its incidence may be related to thyroid index. Thyroid disease may be a risk factor for WMSDs, and increased TSH may be a protective factor for WMSDs.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"129-134"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240119-00028
Y R Zhao, Y M Zheng, L Guan
{"title":"[Advance on risk factors of occupational carpal tunnel syndrome].","authors":"Y R Zhao, Y M Zheng, L Guan","doi":"10.3760/cma.j.cn121094-20240119-00028","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240119-00028","url":null,"abstract":"<p><p>Carpal tunnel syndrome is the most common peripheral nerve compression syndrome and a well-studied form of nerve entrapment syndrome as well. According to the etiology, the risk factors can be divided into individual risk factors and occupational risk factors. Individual risk factors include older age, gender (female), pregnancy, family history, hypothyroidism, diabetes, autoimmune diseases, advanced age, obesity, and wrist trauma, they are also associated with abnormal in the shapes and structures of the wist canal bones and tissues in individuals carpal tunnel bones and tissues. Occupational risk factors include the working posture of hands and wrists, work intensity, and tools, etc., that have attracted more and more attention from occupational disease prevention and control experts and management departments. In addition, the latest research also indicates that social psychosocial factors may also be an important factor in the occurrence and development of carpal tunnel syndrome. Therefore, it is necessary to actively carry out the prevention of occupational carpal tunnel syndrome, reduce the risk of the disease among workers and detect clinical symptoms as early as possible and intervene in time.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"156-160"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-02-20DOI: 10.3760/cma.j.cn121094-20240109-00007
S L Yang, C X Liu, Y Ni, Y Liu, J M Zhang, Q Zeng
{"title":"[Analysis of the difference in CT radiation dose between children's specialized hospitals and general hospitals].","authors":"S L Yang, C X Liu, Y Ni, Y Liu, J M Zhang, Q Zeng","doi":"10.3760/cma.j.cn121094-20240109-00007","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240109-00007","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the differences in pediatric CT radiation dose and scanning parameter Settings between children's specialized hospitals and general hospitals, and to provide reference for the optimization strategy of pediatric CT radiation dose. <b>Methods:</b> From July to August 2022, a stratified sampling method was used to select 7 comprehensive hospitals and 2 children's hospitals in Tianjin, and on-site survey was conducted to collect the dose data of children's head, chest, and abdomen and pelvic CT examinations in these hospitals. The Wilcoxon rank sum test was used to analyze the differences in CTDI(vol) and DLP of the same age group and examination site among different types of hospitals, and the stepwise regression analysis method was used to analyze the effects of age, examination site, and scanning parameters on radiation dose CTDI(vol) and DLP. <b>Results:</b> The CTDI(vol) and DLP of head (1-<5, 5-<10, 10-<15 years old group), chest (5-<10, 10-<15 years old group) and abdomen (1-<5, 5-<10, 10-<15 years old group) in children's specialized hospitals were lower than those in general hospitals (head, 1-<5, 5-<10, 10-<15 years old group, CTDI(vol): <i>Z</i>=-9.32, -6.17, -9.86, <i>P</i><0.001, DLP, <i>Z</i>=-4.41, -4.14, -5.76, <i>P</i><0.001; chest, 5-<10, 10-<15 years old group, CTDI(vol): <i>Z</i>=-3.84, -5.35, <i>P</i><0.001, DLP, <i>Z</i>=-3.59, -4.63, <i>P</i><0.001; abdomen, 1-<5、5-<10 and 10-<15 years old group, CTDI(vol): <i>Z</i>=-7.88, -7.78, -8.53, <i>P</i><0.001, DLP, <i>Z</i>=-7.24, -5.92, -3.44, <i>P</i><0.001). The CT radiation dose in children was positively correlated with age, tube voltage, tube current time product and scan length, and negatively correlated with pitch and hospital type (general hospital and children's hospital) . <b>Conclusion:</b> There are some differences in the CT radiation dose and scanning parameters between children's hospitals and general hospitals. The results indicate that there is still much room for improvement in the optimization of radiation dose in pediatric CT examination.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 2","pages":"117-122"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-01-20DOI: 10.3760/cma.j.cn121094-20240306-00086
Y P Wang, L W Chen, G J Zhao, B Wu, M F Li, Z Q Lu
{"title":"[Analysis of 8 cases of acute chlorfenapyr poisoning].","authors":"Y P Wang, L W Chen, G J Zhao, B Wu, M F Li, Z Q Lu","doi":"10.3760/cma.j.cn121094-20240306-00086","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240306-00086","url":null,"abstract":"<p><p>Chinorhodopyr is a widely used pesticide in agriculture, and the mortality rate of acute chinorhodopyr poisoning patients is high, with no effective treatment currently available. This paper summarized the clinical data of 8 patients with acute chlorfenapyr poisoning recently admitted to the First Affiliated Hospital of Wenzhou Medical University, including clinical manifestations, auxiliary examination and treatment process, so as to provide references for disease diagnosis and treatment, and improve clinicians' understanding of acute chlorfenapyr poisoning.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 1","pages":"72-74"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-01-20DOI: 10.3760/cma.j.cn121094-20240111-00010
Y Gong, Y K Wu, Y H Meng, X F Chen
{"title":"[Ultrasonic-assisted alkaline dilution-inductively coupled plasma mass spectrometry for the determination of total bromine in whole blood].","authors":"Y Gong, Y K Wu, Y H Meng, X F Chen","doi":"10.3760/cma.j.cn121094-20240111-00010","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240111-00010","url":null,"abstract":"<p><p><b>Objective:</b> To establish an inductively coupled plasma mass spectrometry (ICP-MS) method for the rapid determination of total bromine in whole blood, and to provide technical support for the monitoring of bromine exposure in occupational populations. <b>Methods:</b> In September 2023, 0.25 ml of whole blood sample was added with 0.25% tetramethylammonium hydroxide solution to a volume of 5.0 ml, ultrasonicated and homogenized, and then quantified by ICP-MS with rhodium solution as the online internal standard solution. <b>Results:</b> The linear relationship of bromine in blood was good within the range of 0~10.00 mg/L, with a correlation coefficient (<i>r</i>) >0.999. The limit of detection of the method was 0.07 mg/L, and the quantification limit was 0.22 mg/L. The recoveries of the total bromine in whole blood were in the range of 95.5%-102.9%, and the relative standard deviations (RSDs) were in the range of 3.1%-4.7% (<i>n</i>=7) . <b>Conclusion:</b> An ICP-MS method was established for the rapid determination of total bromine in whole blood, which is accurate, simple, rapid, highly automated, and can be used for the determination of total bromine in whole blood of occupationally exposed people.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 1","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华劳动卫生职业病杂志Pub Date : 2025-01-20DOI: 10.3760/cma.j.cn121094-20240322-00111
T J Zhang, J Y Zhang
{"title":"[One case of successful treatment for acute poisoning of the pesticideAcetamiprid and pyridaben].","authors":"T J Zhang, J Y Zhang","doi":"10.3760/cma.j.cn121094-20240322-00111","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240322-00111","url":null,"abstract":"<p><p>Acetamiprid and pyridaben is a compound pesticide, Due to its characteristics of high efficiency, and environmental safety, it has been widely used in agriculture in recent years.This article reports a case of poisoning from a mixture of pymetrozine and propargite pesticides. The patient experienced severe symptoms of poisoning such as vomiting, shortness of breath, abdominal discomfort, generalized cyanosis, bradycardia, and shock after self-administering the pesticide. After admission to the hospital, the patient was treated with atropine to increase heart rate, endotracheal intubation to assist breathing, and norepinephrine to maintain blood pressure. In addition, the patient received gastric lavage, catharsis, hemoperfusion, and continuous blood purification therapy to eliminate the toxins. The patient was successfully treated and discharged after recovery.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 1","pages":"75-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}