中华劳动卫生职业病杂志最新文献

{"title":"[Research progress of volatile organic compound exposure and diabetes mellitus including its complications].","authors":"Q M Liang, W H Chen, X K Zhang","doi":"10.3760/cma.j.cn121094-20240205-00048","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240205-00048","url":null,"abstract":"<p><p>Volatile organic compounds (VOCs) are a type of organic compounds that exist in the form of vapor in the air at room temperature, and are common pollutants in industrial production and living environments. The health hazards caused by exposure to VOCs are gradually gaining recognition and social attention. At present, the research on the harm of VOCs to human health mainly involves the respiratory system, cardiovascular system and nervous system. However, in recent years, people have realized that VOCs can induce glucose metabolism disorder through insulin resistance, oxidative stress and oxidative damage, inflammatory reaction and liver damage, leading to increased blood sugar and increased potential risk of diabetes, and even increased the risk of complications of diabetes. This review summarizes the epidemiology and related mechanisms of VOCs, diabetes and its complications, providing a reference for effective prevention and control of VOC induced diabetes.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"552-557"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study on subacute toxicity of p-chloro-m-xylenol in rats].","authors":"S F Li, Q H Zhou, M Zhao, Y H Liu, D M Zhou, Z Y Qian","doi":"10.3760/cma.j.cn121094-20240410-00157","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240410-00157","url":null,"abstract":"<p><p><b>Objective:</b> To study the subacute oral toxic effect of p-chloro-m-xylphenol on rats and provide a basis for its safety evaluation. <b>Methods:</b> SPF-grade Wistar rats were randomly divided into 4 groups according to body weight stratification randomization, with 20 rats in each group, half male and half female. The set concentrations of the p-chloro-m-xylphenol dose groups were 11.25, 22.50, and 45.00 mg/kg·BW respectively, with an intragastric volume of 10 ml/kg·BW. The blank control group was given the same amount of distilled water. The rats were treated with intragastric administration for 30 days. After intraperitoneal injection of 50 mg/kg·BW pentobarbital sodium for anesthesia, bloodletting and death, the organs were separated and weighed. Blood was collected from the abdominal aorta to determine the hematological and serum biochemical indicators of the whole blood of rats. Multiple groups comparison was performed by one-way analysis of variance, and pairwise comparison between groups was performed by the least significant difference test or Dunnett-t3 test. <b>Results:</b> The kidney weight in the 45.00 mg/kg·BW dose group of female rats [ (1.59±0.11) g] was lower than that in the blank control group [ (1.71±0.12) g], and the difference was statistically significant (<i>P</i><0.05) . The percentage of monocytes in the 11.25 mg/kg·BW dose group of male rats [ (4.81±0.74) %] was lower than that in the blank control group [ (5.86±0.58) %], the red blood cell count [ (6.93±0.26) ×10(12)/L] and hemoglobin [ (134.30±4.95) g/L] in the 22.50 mg/kg·BW dose group of female rats were both lower than those in the blank control group[ (7.48±0.26) ×10(12)/L, (146.20±4.42) g/L], the percentage of eosinophils in the 11.25 mg/kg·BW dose group of female rats [ (2.46±0.86) %] was higher than that in the blank control group [ (1.66±0.41) %], and the differences were statistically significant (<i>P</i><0.05) . <b>Conclusion:</b> P-chloro-m-xylphenol may have toxic effects on the blood system of rats, and the kidneys may be the potential target organs for its toxicity.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"529-532"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The method of determination for trichloroaniline in the air of workplace by liquid chromatography with solvent elution].","authors":"B B Chen, S Y Zheng, S R Yang, X L Fang, R F Li","doi":"10.3760/cma.j.cn121094-20240313-00095","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240313-00095","url":null,"abstract":"<p><p><b>Objective:</b> To establish a solvent elution-liquid chromatography method for the determination of trichloroaniline concentration in the air of the workplace. <b>Methods:</b> From December 2023 to January 2024, 2, 4, 5-trichloroaniline, 2, 4, 6-trichloroaniline, and 3, 4, 5-trichloroaniline in the air were collected using glass fiber filter membranes. After elution with acetonitrile and filtration with a 0.22 μm mixed cellulose filter membrane, isometric elution with acetonitrile and water (volume ratio 55∶45) was performed using a C8 column (250 mm×4.6 mm×5 μm) , and detection was carried out using a photo-diode array (PDA) detector. The detection limit, precision and other indicators of the method were analyzed. <b>Results:</b> The separation and determination of trichloroaniline isomers were completed within 9 minutes by the solvent elution-liquid chromatography method. The linear range was 0.1-30 μg/ml, the detection limit of the method was 0.005 μg/ml, the recoveries were 88%-98%, and the relative standard deviation was 0.3%-3.2%. <b>Conclusion:</b> The solvent elution-liquid chromatography method for the determination of trichloroaniline is simple and efficient. Both the recovery and precision meet the standard requirements for the determination of toxic substances in the workplace, and it is suitable for the detection of trichloroaniline in the workplace.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"539-542"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Meta-analysis of incidence and influencing factors of low back pain among automobile manufacturing workers in China].","authors":"N Liu, W D Ma, Q Ning","doi":"10.3760/cma.j.cn121094-20240403-00138","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240403-00138","url":null,"abstract":"<p><p><b>Objective:</b> To systematically evaluate the incidence of low back pain (LBP) and analyze its main influencing factors among automobile manufacturing workers in China. <b>Methods:</b> In March 2024, literatures related to LBP of workers in the automotive manufacturing industry were retrieved from China National Knowledge Infrastructure (CNKI) , VIP China Science and Technology Journal Database, Wanfang Database, PubMed, and Web of Science Database. The search time range was from the establishment of the database to March 2024, and the literature was screened according to the inclusion and exclusion criteria. After evaluating the quality of the article using the quality evaluation criteria recommended by the Agency for Healthcare Research and Quality in the United States, Stata 17.0 software was used for analysis. Random effects models or fixed effects models were selected based on the degree of heterogeneity to calculate the combined effect size, and subgroup analysis and analysis of influencing factors of LBP were conducted. <b>Results:</b> A total of 16 articles were included, with a total sample size of 22245 people. The literature quality score ranged from 6 to 8 points. The results of the Meta-analysis showed that the incidence of LBP among automobile manufacturing workers in China was 32% (95%<i>CI</i>: 22%, 42%) . The results of subgroup analysis showed that the incidence of LBP among automotive manufacturing workers aged ≥30 years was 39% (95%<i>CI</i>: 22%, 57%) , which was higher than that among automotive manufacturing workers aged <30 years (24%, 95%<i>CI</i>: 17%, 32%) . The incidence of LBP among automotive manufacturing workers with a length of service of ≥5 years was 40% (95%<i>CI</i>: 23%, 56%) , which was higher than that among automotive manufacturing workers with a length of service of <5 years (24%, 95%<i>CI</i>: 16%, 33%) . The incidence of LBP reported from 2011 to 2017 (39%, 95%<i>CI</i>: 18%, 60%) was higher than that from 2018 to 2023 (28%, 95%<i>CI</i>: 20%, 36%) . Working in an uncomfortable posture (<i>OR</i>=3.72, 95%<i>CI</i>: 2.05, 6.77) , standing for a long time while working (<i>OR</i>=1.97, 95%<i>CI</i>: 1.61, 2.42) , carrying heavy objects (<i>OR</i>=1.93, 95%<i>CI</i>: 1.63, 2.30) , bending over while working (<i>OR</i>=1.86, 95%<i>CI</i>: 1.60, 2.17) and frequent overtime work (<i>OR</i>=2.38, 95%<i>CI</i>: 1.44, 3.92) were both risk factors for LBP among workers in the automotive manufacturing industry (<i>P</i><0.05) , while sufficient rest time (<i>OR</i>=0.55, 95%<i>CI</i>: 0.48, 0.63) was a protective factor (<i>P</i><0.05) . <b>Conclusion:</b> The incidence of LBP among workers in China's automotive manufacturing industry is relatively high. Working in an uncomfortable posture, standing for a long time, carrying heavy objects, bending over for work, frequent overtime work and sufficient rest time are the influencing factors of LBP among workers in the automotive manufacturing industry. Preven","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"523-528"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress on DNA methylation as a diagnostic biomarker for malignant mesothelioma].","authors":"L Cui, X L Zheng, M Zhang","doi":"10.3760/cma.j.cn121094-20240417-00170","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240417-00170","url":null,"abstract":"<p><p>Malignant mesothelioma is a rare tumor that is highly correlated with asbestos exposure. Due to the insidious early symptoms, mesothelioma is usually diagnosed in the advanced stages of the disease. Therefore, there is an urgent need for some early detection biomarkers to assist in the diagnosis of mesothelioma. The detection of DNA methylation can be one of the new research directions. This article provides a comprehensive discussion on the research progress of DNA methylation in malignant mesothelioma, including genes that can serve as diagnostic markers for malignant mesothelioma and the current problems in clinical application. It also provides new insights for future research directions using DNA methylation as a diagnostic marker for mesothelioma.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"547-551"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of occupational ultraviolet cataract caused by magnetic particle testing].","authors":"J Hu, M Chen, Y J Xie, M R Zhang, F Zhang, J R Dou","doi":"10.3760/cma.j.cn121094-20240402-00136","DOIUrl":"10.3760/cma.j.cn121094-20240402-00136","url":null,"abstract":"<p><p>Magnetic particle testing, as an efficient non-destructive testing method, has been widely applied in the field of defect detection for precision components. This study reports a case of occupational ultraviolet cataract caused by prolonged exposure of a magnetic particle testing worker to ultraviolet radiation exceeding standard intensity levels. Insufficient awareness of the potential ocular damage caused by long-wave ultraviolet radiation, inadequate provision of protective goggles, and non-compliant occupational hygiene monitoring and health examinations were identified as the primary contributing factors to this case.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"533-536"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Characteristics of 972 poisoning inpatients].","authors":"L Yan, Y Y Wang, Y Peng, W He, J L Tang","doi":"10.3760/cma.j.cn121094-20240407-00150","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240407-00150","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the clinical characteristics of poisoning inpatients in the first affiliated hospital of chongqing medical and pharmaceutied hospital, and to provide basis for improving the level of prevention, control, diagnosis and treatment of regional poisoning. <b>Methods:</b> In January 2024, using the HIS medical record system of The First Affiliated Hospital of Chongqing Medical and Pharmeceutical College, we collected the clinical data of poisoning inpatients admitted to our hospital from 2018 to 2023. The data of sex, age, time of poisoning, poison species, poisoning cause, poisoning route, season, treatment and prognosis were analyzed. <b>Results:</b> A total of 972 patients were enrolled, among whom 71.71% (697/972) were young and middle-aged adults, with a higher incidence in summer. Chemical poisoning accounted for 53.61% (521/972) , followed by pesticide poisoning and mixed poisoning in the second and third places. The overall detection rate of toxins was 58.23% (566/972) . The number of domestic poisonings increased year by year, while occupational poisonings decreased year by year, with statistically significant differences (<i>P</i><0.05) . The overall cure and improvement rate was 97.22% (945/972) , and the cure and improvement rate of pesticide poisoning was the lowest at 90.23% (120/133) . Factors such as age >60 years, intentional exposure to toxins, pesticide exposure, gastric lavage, blood purification, and length of hospital stay affected the prognosis of patients (<i>P</i><0.05) . <b>Conclusion:</b> Health education should be actively promoted, toxin control should be strengthened, scientific and reasonable prevention and control measures as well as treatment methods should be adopted to reduce the incidence and mortality of poisoning.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"504-507"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Status analysis of standard methods for detecting pesticide in the air of workplace in China].","authors":"D D Cao, L Zhong, Y Ye, X Y Hu","doi":"10.3760/cma.j.cn121094-20240702-00293","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240702-00293","url":null,"abstract":"<p><p>This article analyzes the current standard methods for detecting occupational hazards of pesticides in the air of workplaces in China, including sampling, pre-treatment, laboratory analysis, as well as the matching status between the minimum quantitative concentration of methods and occupational exposure limits. Among the 46 pesticide occupational hazard factors with occupational exposure limits, only 25 are supported by current valid standard detection methods. The minimum quantitation concentrations given in only 7 standard detection methods are lower than 10% of the occupational exposure limits, which meet the requirements for classified control.This study discusses the problems existing in the current standard methods for detecting pesticide and provides reference for further improving the standard methods.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"543-546"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Resource distribution and current status of diagnosis and treatment of clinical nuclear medicine in Gansu Province in 2023].","authors":"L M Niu, Y Wang, Y Li, G Liu","doi":"10.3760/cma.j.cn121094-20240329-00130","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240329-00130","url":null,"abstract":"<p><p><b>Objective:</b> To analysis the current utilization of nuclear medicine diagnosis and treatment equipments in Gansu province, evaluate the fairness of its distribution and provide a theoretical basis for government decision-making and the allocation of nuclear medicine diagnosis and treatment resources. <b>Methods:</b> In May 2023, Basic data were collected through questionnaires from the \"Occupational Radiation Disease Monitoring\" and \"Radiation Protection Monitoring in Medical and Health Institutions\" projects undertaken by Gansu Provincial Center for Disease Control and Prevention.The Gini coefficient and Theil index were calculated using STATA SE software to evaluate the equity of clinical nuclear medicine diagnosis and treatment resource allocation. Simultaneously, personal dose monitoring was conducted for nuclear medicine personnel. The fairness of clinical nuclear medicine diagnosis and treatment resource allocation was evaluated using the Gini coefficient and Theil index. <b>Results:</b> As of December 31, 2023, a total of 12 medical institutions in Gansu Province engaged in nuclear medicine diagnosis and treatment, employing 137 nuclear medicine radiation workers. Throughout the province, there were a total of 3 PET/CT scanners, 13 SPECT scanners and 3 medical cyclotrons available. In addition, 33712 nuclear medicine diagnostic procedures and 9365 various types of nuclear medicine treatments were administered over the year, resulting in a diagnostic frequency of 1.35 procedures per thousand population and a treatment frequency of 0.37 procedures per thousand population. The Gini coefficients for nuclear medicine personnel, equipment and diagnostic and treatment applications calculated per capita were 0.50, 0.53 and 0.61, respectively. The corresponding Theil indices were 0.0672, 0.0669 and 0.1277. In 2023, the average annual effective dose from external exposure for nuclear medicine workers was 0.37 mSv per person, while the average annual effective dose from internal exposure to thyroid (131)I for nuclear medicine workers was 1.41 mSv. <b>Conclusion:</b> The distribution of nuclear medicine health resources and applications in Gansu Province is uneven. Greater emphasis should be placed on strengthening the adjustment of nuclear medicine resource allocation between regions, continuously promoting coordinated development within regions, and improving dose monitoring for nuclear medicine personnel.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"517-522"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Machine learning analysis of the influence of workload factors and social psychological factors on WMSDs].","authors":"S Q Chen, C Tang, Y Yao, B F Lu, Y Mei, Z L Chen","doi":"10.3760/cma.j.cn121094-20240305-00083","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240305-00083","url":null,"abstract":"<p><p><b>Objective:</b> To explore the effects of workload factors and social psychological factors on work-related musculoskeletal disorders (WMSDs) , construct a preventive decision-assisted ensemble learning model, and propose screening methods with clinical significance. <b>Methods:</b> In October 2022, 1071 workers from optoelectronic enterprises were selected as the research subjects by cluster sampling method. The general situation of workers, workload factors, social psychological factors and the occurrence of WMSDs were collected by using questionnaires. logistic regression, Extreme Gradient Boosting (XGBoost) , ensemble learning and classification chain model were adopted to explore the key factors influencing WMSDs, and the area under curve (AUC) was used to evaluate the model performance. <b>Results:</b> The incidence of WMSDs among workers in optoelectronic enterprises in the past year was 47.7% (511/1071) , among which the incidence of multi-site WMSDs was 54.4% (278/511) . logistic regression analysis showed that prolonged sitting, personnel shortage and forward neck tilt were risk factors for the occurrence of WMSDs in workers (<i>P</i><0.05) . XGBoost identified the key social psychological factors influencing WMSDs as low mood, mental tension, perceived happiness level, psychological calmness and tranquility. The integrated classification chain model based on the ordered label order had certain efficacy (AUC>0.7) when analyzing WMSDs at the neck, waist, shoulder, back, elbow and hip positions. <b>Conclusion:</b> Workload factors are the main risk factors for the occurrence of WMSDs among workers in optoelectronic enterprises, and social psychological factors also have potential influences. The construction of a classification chain model can accurately identify the occurrence of WMSDs in multiple parts. The alternating prevention strategy of workload factors and social psychological factors has important public health significance.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 7","pages":"498-503"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}