中华劳动卫生职业病杂志最新文献

{"title":"[Determination of two derivatives of cyanide in biomaterials by headspacegas gas chromatography mass spectrometry].","authors":"C C Guan, C Z Ni","doi":"10.3760/cma.j.cn121094-20240513-00214","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240513-00214","url":null,"abstract":"<p><p><b>Objective:</b> To establish a method for determination of two derivatives of cyanide in biomaterials by headspace gas chromatography mass spectrometry. <b>Methods:</b> In February 2024, blood and urine samples were placed in headspace sampling vials. Phosphoric acid, or phosphoric acid and chloramine T solution, was added respectively to derivatize cyanide into hydrogen cyanide or cyanogen chloride. After equilibrating at 80°C for 15 minutes, headspace sampling was performed. The samples were separated by a GS-GasPro chromatographic column and determined by gas chromatography-mass spectrometry in selected ion monitoring (SIM) mode. Qualitative analysis was conducted using both retention time and the ratio of characteristic ions, and quantitative analysis was carried out by the external standard method. <b>Results:</b> The correlation coefficients (r) for the two derivatives was 0.9992 and 0.9984, respectively. The detection limits was 0.10 μg/ml and 0.05 μg/ml, respectively. The recoveries ranged from 73.7% to 98.4%, with precision (RSD) ranging from 3.3% to 14.2%. <b>Conclusion:</b> The method offers the advantages of simple operation, precise quantification, high qualitative reliability, and high sensitivity, making it suitable for cyanide detection in biological materials.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"622-624"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of thyroid examination results among interventional radiation workers in Tianjin from 2020 to 2022].","authors":"Y N Du, P Hao, Y L Yu, J W Yu, L N Fan, X Y Yang","doi":"10.3760/cma.j.cn121094-20240522-00231","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240522-00231","url":null,"abstract":"<p><p><b>Objective:</b> To investigate and analyze the thyroid examination results and influencing factors of interventional radiation workers in Tianjin. <b>Methods:</b> In February 2023, A convenient sampling method was used to select the staff engaged in interventional radiation work in an occupational health inspection institution in Tianjin from 2020 to 2022 as the study object. After excluding the incomplete data, 1080 people were included, and 363 medical staff with non-radiological work during the same period were included as the control group. To analyze the individual doses and occupational health examination data of interventional radiation workers, and to analyze the possible influencing factors of thyroid abnormalities. <b>Results:</b> The cumulative dose <i>M</i> (<i>Q</i>(1), <i>Q</i>(3)) of interventional radiation workers was 1.039 (0.528, 1.905) mSv. The levels of FT(3) and FT(4) in the intervention group were higher than those in the control group, while TSH levels were lower than those in the control group (<i>Z</i>=4.84、6.03、-5.82, <i>P</i><0.05). The levels of FT(3) and FT(4) in female interventional radiation workers were lower than those in males, while the levels of TSH were higher than those in males (<i>Z</i>= -17.54、-6.65、3.61, <i>P</i><0.05). There were statistically significant differences in FT(3) levels among different ages, differen tradiation exposure years, different initial age of exposure to radiation, and different cumulative doses (<i>H</i>=47.22、11.33、16.70, <i>Z</i>=-2.48, <i>P</i><0.05). There were statistically significant differences in thyroid ultrasound abnormalities among different genders, different ages, different initial age of exposure to radiation, and different cumulative doses (<i>χ</i>(2)=28.02、61.12、17.87、11.30, <i>P</i><0.05). The results of logistic regression analysis showed that the influencing factors of FT(3) distributed in the low-level group were female (<i>OR</i>=10.53, 95%<i>CI</i>: 7.66-14.47, <i>P</i><0.05), and age 40-49, ≥50 years old (<i>OR</i>=2.40, 95%<i>CI</i>: 1.12-5.14 <i>OR</i>=3.79, 95%<i>CI</i>: 1.59-9.03, <i>P</i><0.05). The influencing factors of thyroid ultrasound abnormalities were female (<i>OR</i>=1.92, 95%<i>CI</i>: 1.48-2.50, <i>P</i><0.05) and age ≥50 years old (<i>OR</i>=3.93, 95%<i>CI</i>: 1.91-8.09, <i>P</i><0.05) . <b>Conclusion:</b> Long term low dose ionizing radiation has a certain effect on FT(3), FT(4) and TSH levels of interventional radiation workers. Gender and increased age are possible influencing factors of the decreased FT(3) levels and thyroid ultrasound abnormalities.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"610-614"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of earplugs protective and intervention effect of 220 noise exposed workers].","authors":"Y N Wang, W T Lin, C H Liao, L Lu, S B Su","doi":"10.3760/cma.j.cn121094-20240403-00139","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240403-00139","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the use of earplugs among noise-exposed workers (Homo sapiens) in Bao'an District, Shenzhen, measure the personal attenuation rating (PAR) of earplugs when wearing earplugs, (Homo sapiens), analyze factors influencing the protective effect of earplugs, and evaluate the role of targeted wearing interventions in improving protective efficacy. <b>Methods:</b> From December 2022 to January 2023, 220 workers in noise-exposed positions from 3 enterprises in Bao'an District, Shenzhen were selected as subjects using the convenience sampling method. The Personal Attenuation Rating (PAR) values of workers wearing earplugs were measured using a fit testing system. Combined with the results of a questionnaire survey, the individual differences in workers' baseline PAR were described. A multivariate logistic regression model was used to analyze the influencing factors for earplugs to achieve the protective effect. One-on-one wearing interventions were implemented for workers who failed to achieve the protective effect, and repeated PAR tests were conducted. The changes in PAR of 120 workers before and after the intervention were compared. <b>Results:</b> The median baseline PAR for 220 workers was 7 (0, 14) dB, and the intervention rate was 54.55% (120/220). There were differences in the baseline PAR of workers with different length of service, earplugs wearing time and experience, daily noise exposure time and intensity, training and the comfort of earplug use (<i>P</i><0.05). The results of multivariate regression analysis showed that workers The comfort with earplugs wearing (<i>OR</i>=2.81, 95%<i>CI</i>: 1.49~5.33, <i>P</i><0.01) and training (<i>OR</i>=6.60, 95%<i>CI</i>: 1.70~25.63, <i>P</i><0.05) were the influencing factors of achieving the protective requirement. The median PAR was increased to 13 (11, 16) dB after intervention. <b>Conclusion:</b> The baseline protective effect of earplugs worn by workers is significantly influenced by comfort and enterprise training. One-on-one interventions can effectively improve the protective efficacy of those who fail to meet the requirements.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"590-594"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Determination of strychnine in human serum by liquid chromatography tandem mass spectrometry].","authors":"X H Chen, C Qin, J Zhou","doi":"10.3760/cma.j.cn121094-20240411-00160","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240411-00160","url":null,"abstract":"<p><p><b>Objective:</b> To establish a method for the determination of strychnine in human serum by liquid chromatography tandem mass spectrometry. <b>Methods:</b> In April 2024, the serum samples were extracted using alkaline ethyl acetate. Separation was achieved using a Waters HSS T3 column (100 mm×2.1 mm, 1.8 μm) with a linear gradient elution program of water/acetonitrile (containing 5 mmol/L ammonium formate and 0.1% formic acid) as the mobile phase. The analyte was detected by using electrospray ionization (ESI) in the positive multiple reaction monitoring (MRM) mode and quantified using an internal standard method. <b>Results:</b> A good linearity was obtained in the concentration range of 0.01~20.0 μg/L for target compound with the correlation coefficients≥0.999. The limitof detection (LOD) and the limit of quantitation (LOQ) were 0.003 μg/L and 0.01 μg/L, respectively. The average spiked recovery was 101.3%, the intra-day precision was 2.8%-5.4%, and the inter-day precision was 3.9%-6.3%, respectively. <b>Conclusion:</b> Liquid chromatogrphy tandem mass spectrometry method exhibits high sensitivity, strong specificity, and good accuracy, and can be used for the determination of strychnine in Homo sapiens serum.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"615-618"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Fast determination of maduramicin ammonium in serum by high performance liquid chromatography-tandem mass spectrometry].","authors":"B Zhou, B W Cheng, J Ma, F Dong, R C Liu, H L Li","doi":"10.3760/cma.j.cn121094-20240518-00224","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240518-00224","url":null,"abstract":"<p><p><b>Objective:</b> To establish a high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for the fast determination of maduramicin ammonium (MAD) in rat serum. <b>Methods:</b> In February 2024, rat serum samples were selected and directly injected after extraction and purification with methanol: acetonitrile (1: 1), separated on a C18 chromatographic column, and gradient-eluted using 0.1% formic acid aqueous solution -0.1% formic acid methanol solution as the mobile phase. Under optimized instrument conditions, electrospray positive ion multiple reaction monitoring (MRM) mode was employed for quantification using the external standard method, followed by methodological validation of the established approach. <b>Results:</b> The linearity of MAD in serum was good in the concentration range of 0.5-100 μg/L, and the correlation coefficient was 0.9997. The mean recoveries of MAD from spiked samples were 86.0%-109.6%, with the relative standard deviations were less than 10%. The limit of detection was 0.23 μg/L, The limit of detection was 0.75 μg/L. <b>Conclusion:</b> This method is high sensitive and reliable, which is suitable for the determination of MAD in in mouse serum.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"619-622"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of occupational allergic contact dermatitis caused by sinomenine hydrochloride].","authors":"M X Lu, Q Fu, L F Tan, L J Ling","doi":"10.3760/cma.j.cn121094-20240329-00129","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240329-00129","url":null,"abstract":"<p><p>Sinomenine hydrochloride is an alkaloid preparation commonly used in clinical practice in traditional Chinese medicine, and allergic reactions induced by occupational exposure to it are relatively rare in clinical settings. This article analyzes a case of allergic contact dermatitis in a medical worker after occupational exposure to sinomenine hydrochloride. The patient developed generalized skin rashes with the fingertips as the initial site three months after exposure to sinomenine hydrochloride. The treatment effect was poor without cessation of exposure, while symptoms significantly improved after cessation. The condition persisted, exhibiting a contact-reaction pattern of recurrence upon re-exposure. The serum total IgE level met the criteria for extremely severe allergy. No similar symptoms were observed among colleagues in the same position. After differential diagnosis, the possibility of dermatomyositis was ruled out, and the patient was diagnosed with occupational allergic contact dermatitis.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"629-631"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exploration of ribosomal DNA copy number as an early biomarker for exposure to chemical carcinogens].","authors":"C Ding, H D Xu, J L Lou","doi":"10.3760/cma.j.cn121094-20240417-00169","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240417-00169","url":null,"abstract":"<p><p>As the relationship between exposure to chemical carcinogens and human health risks becomes increasingly clear, identifying effective biomarkers to reveal early exposure and prevent the occurrence and development of tumors has become particularly critical. Ribosomal DNA (rDNA), a cluster of genes encoding ribosomal RNA, has emerged as a focal point in chemical carcinogen exposure research in recent years, due to its high copy number within cells and sensitivity to environmental stimuli. The dynamic changes in rDNA copy numbers, especially the significant alterations observed following exposure to environmental carcinogens, have rendered it a promising potential biomarker. This paper aims to systematically review the theoretical underpinnings and research progress of rDNA copy numbers as a biomarker for exposure to chemical carcinogens, and further discuss the challenges and prospects in future research and applications.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"635-640"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Visual analysis for published literature in the Chinese Journal of Industrial Hygiene and Occupational Diseases from 1983 to 2023].","authors":"X Wu, T Liu, X Wang","doi":"10.3760/cma.j.cn121094-20240508-00203","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240508-00203","url":null,"abstract":"<p><p><b>Objective:</b> To conduct a visual analysis of the papers published in the Chinese Journal of Industrial Hygiene and Occupational Diseases since its inception, and to understand the current situation and development trends in the field of occupational health and occupational diseases. <b>Methods:</b> A total of 9894 papers published in the Chinese Journal of Industrial Hygiene and Occupational Diseases from January 1, 1983 to December 31, 2023 were retrieved from China National Knowledge Infrastructure (CNKI) in February 2024. Non-academic literature was screened and excluded. Excel 2010 and SPSS 24.0 were used to analyze the annual publication situation. Visualization software CiteSpace V6.2.R7 was used to conduct co-occurrence analysis, cluster analysis and emergence analysis for keywords and to make knowledge graph. <b>Results:</b> A total of 9381 literatures were included. From 1983 to 2023, the annual publication volume in Chinese Journal of Industrial Hygiene and Occupational Diseases showed an M-shaped fluctuation, with the largest number of literatures published in 2010 (351 literatures). The co-occurrence analysis of keywords showed that the occurrence frequency of keywords such as poisoning, pneumoconiosis, occupational exposure and silicosis was high. By cluster analysis, the literature keywords were summarized into 10 clusters of pneumoconiosis, noise, stress, microwave, paraquat, poisoning, chromatography, polymorphism, silicosis, and yellow phosphorus. The emergence analysis showed that occupational stress, influencing factors, occupational health, occupational diseases and pneumoconiosis were the top 5 keywords of emergence intensity, while noise and hearing loss were the keywords of greater emergence intensity after 2020. <b>Conclusion:</b> The contents of the studies on pneumoconiosis and poisoning published in the Chinese Journal of Industrial Hygiene and Occupational Diseases are relatively stable, while occupational stress and noise have become research hot spots in recent years. It is suggested to strengthen the cross and integration of multi-disciplines in order to promote the development of occupational health and occupational disease fields.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"580-585"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study on the method of estimating upper limb reachable workspace based on shoulder joint dynamic positioning].","authors":"C Zhang, Z J Zhou, H Q Xu, L H Ran, H M Hu, X Zhang, J P Shi","doi":"10.3760/cma.j.cn121094-20240814-00381","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240814-00381","url":null,"abstract":"<p><p><b>Objective:</b> To propose a functional method for locating the shoulder joint center of rotation aimed at rapid estimation of the upper limb reachable domain envelope, thereby informing ergonomic design and task optimization. <b>Methods:</b> In March 2024, shoulder kinematics during gait were recorded from ten adults using a three-dimensional motion-capture system. Assuming the existence of a point near the glenohumeral joint that maintains a fixed spatial relationship to the humerus and the acromion, we estimated both static and dynamic centers of rotation. Localization accuracy was quantified by the standard deviation of distance residuals to upper-arm markers. Upper-limb joint angles and anthropometric parameters were modeled via regression; combined with maximal joint ranges of motion, these were used to infer the reachable domain envelope. <b>Results:</b> The static center of rotation was located approximately twenty-two millimeters medial to the acromial landmark in the coronal plane and thirty-seven millimeters inferior to it. The standard deviation of the residuals for the distances from the dynamic shoulder joint center of rotation to upper-arm markers averaged 1.02 mm, which was 47.42% lower than that of the static center of rotation and 66.56% lower than that of the acromion. Moreover, the trajectory of this dynamic center showed a strong correlation with upper-limb joint angles (<i>R</i>(2)>0.7) . <b>Conclusion:</b> The proposed method enables rapid and accurate estimation of the upper limb reachable domain envelope to support ergonomic design and may help reduce the risk of work-related musculoskeletal disorders.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"561-566"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effect of mouse nerve growth factor combined with neostigmine on nerve repair after envenoming bites by Bungarus multicinctus].","authors":"J L Peng, X L Xiao, C J Song","doi":"10.3760/cma.j.cn121094-20240530-00244","DOIUrl":"10.3760/cma.j.cn121094-20240530-00244","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To evaluate the efficacy and clinical application value of mouse nerve growth factor combined with neostigmine in the treatment of nerve injury in patients bitten by Bungarus multicinctus by a prospective single-blind controlled clinical study. &lt;b&gt;Methods:&lt;/b&gt; In June 2020, a prospective, single-blindness, randomized grouping method was used to select patients with bungarus multicinctus saurogobio dabryi subsp. dabryi bite injuries admitted to the Emergency Department of Ganzhou People's Hospital in Jiangxi Province as the study subjects. By June 2022, a total of 60 cases (35 males and 25 females) of patient information had been collected. The patients were divided into two groups &lt;4 h and ≥4 h after being bitten by bungarus multicinctus. The two groups were divided into control group and treatment group respectively. The treatment group was given an intramuscular injection of neostigmine 1mg q8 h and mouse nerve growth factor 18 μg/d based on conventional treatment. The control group was only given conventional treatment. Myasthenia Gravis Composite Scale (MGC) scores were performed for all patients at admission, 4 hours, 8 hours, and 24 hours. Muscle strength was continuously assessed and the recovery time of muscle strength was recorded. Quantitative data comparisons between groups at admission were analyzed using one-way ANOVA, while qualitative data comparisons were conducted using χ2 tests. Variables showing intergroup differences in baseline measurements (Parazacco spilurus subsp. spilurus) were treated as covariates, with treatment outcomes post-admission compared via analysis of covariance (ANCOVA). Pairwise comparisons of quantitative data between groups employed the Bonferroni method. Baseline quantitative data correlation analysis utilized Pearson correlation, followed by partial correlation analysis after controlling for grouping variables. &lt;b&gt;Results:&lt;/b&gt; The MGS scores of the treatment group in both the ≥4 h and &lt;4 h patient groups were lower than those of the control group at the same time points (&lt;i&gt;P&lt;/i&gt;&lt;0.05). After adjusting for the influence of MGS scores at admission, the muscle strength recovery time in the ≥4 h treatment group was significantly shorter compared to the control group, with a statistically significant difference (&lt;i&gt;P&lt;/i&gt;&lt;0.001). MGS scores at 4 h, 8 h, and 24 h after admission were positively correlated with muscle strength recovery time (&lt;i&gt;r&lt;/i&gt;=0.540, 0.720, 0.640, respectively, &lt;i&gt;P&lt;/i&gt;&lt;0.001). Muscle strength recovery time was positively correlated with disease duration (&lt;i&gt;r&lt;/i&gt;=0.910, &lt;i&gt;P&lt;/i&gt;&lt;0.001). Disease duration was positively correlated with MGS scores at admission (&lt;i&gt;r&lt;/i&gt;=0.908, &lt;i&gt;P&lt;/i&gt;&lt;0.001) and with muscle strength recovery time (&lt;i&gt;r&lt;/i&gt;=0.757, &lt;i&gt;P&lt;/i&gt;&lt;0.001). After controlling for grouping, the correlation coefficient increased, showing a strong correlation (&lt;i&gt;r&lt;/i&gt;=0.892, &lt;i&gt;P&lt;/i&gt;&lt;0.001) . &lt;b&gt;Conclusion:&lt;/b&gt; The combination of mouse nerve growth factor and ne","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 8","pages":"567-572"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}