中华劳动卫生职业病杂志最新文献

{"title":"[Determination of six psychotropic drug metabolites in human plasma by LC-MS/MS method].","authors":"Y X Cui, H L Li, Y Yu, J Ma, B Zhou, F Dong","doi":"10.3760/cma.j.cn121094-20240207-00053","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240207-00053","url":null,"abstract":"<p><p><b>Objective:</b> To establish a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of N-desalkylquetiapine, hydroxybupropion, N-desmethyl clozapine, N-desmethyl clomipramine, O-desmethyvenlafaxine and dehydro aripiprazole in human plasma. <b>Methods:</b> In June 2023, plasma samples were treated with methanol-acetonitrile (volume ratio of 1∶1) for protein precipitation and then detected by LC-MS/MS. It was separated by C18 column and eluted with 5 mmol/L ammonium acetate water and 5 mmol/L ammonium acetate methanol solution as mobile phase gradient. The metabolites of six psychotropic drugs were qualitatively and quantitatively by using electrospray positive ion multi-reactive ion monitoring scanning mode (MRM) . <b>Results:</b> The linear relationships of six psychotropic drug metabolites were good in the concentration range of 2-100 μg/L. The linear correlation coefficients were 0.9971-0.9999, the limits of quantification of the method were 0.10-6.00 μg/L, and the inter-and intra-day precision were 4.6%-9.8% and 1.5%-8.6%, with the recoveries of the spiked standards ranged from 90.0% to 106.1%. <b>Conclusion:</b> The LC-MS/MS method for the determination of metabolites of six psychotropic drugs in human plasma is simple, rapid and sensitive, and can be used for the qualitative and quantitative determination of metabolites in plasma samples of patients suspected of psychotropic drug poisoning.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"445-448"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Progress in diagnosis and treatment of occupational decompression sickness].","authors":"Y Y Jin, X Y Kuang","doi":"10.3760/cma.j.cn121094-20240229-00079","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240229-00079","url":null,"abstract":"<p><p>Occupational decompression sickness is one of the occupational diseases caused by high pressure work. The pathogenesis and pathological changes of decompression sickness are related to the formation of bubbles inside and outside blood vessels and in tissues. The diagnosis of occupational decompression sickness includes acute decompression sickness and decompression osteonecrosis. Corresponding treatment measures should be taken according to the symptoms, signs and severity of decompression disease. In this paper, the incidence, diagnosis and treatment of decompression sickness were reviewed to provide basis for early prevention of decompression sickness.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"477-480"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of health effects of occupational exposure to Dimethylformamide].","authors":"Q Q Gao, Z J Jiang, L Zhou, L Han, Y Zhao","doi":"10.3760/cma.j.cn121094-20240325-00118","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240325-00118","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To analyze the abnormal results of health surveillance for workers exposed to dimethylformamide (DMF), and to provide reference for the formulation of relevant policies and standards. &lt;b&gt;Methods:&lt;/b&gt; In April 2024, 11, 224 workers who participated in occupational health examinations in Jiangsu Province in 2023 were selected as the research subjects. Among them, 5, 615 people exposed to DMF were taken as the exposure group, and 5, 609 people not exposed to hepatotoxic chemicals were taken as the control group. By inquiring about related symptoms and combining with the occupational health examination of workers, the abnormal rates of blood pressure, blood routine, urine routine, electrocardiogram, liver function and B-ultrasonography of the survey subjects were statistically analyzed. &lt;b&gt;Results:&lt;/b&gt; Compared with the control group, the abnormal detection rates of indicators such as blood pressure, blood routine, urine routine, and electrocardiogram were higher, and the difference was statistically significant &lt;i&gt;P&lt;/i&gt;&lt;0.05). The abnormal rates of various liver function indicators in the DMF exposure group were all higher than those in the control group. Among them, the abnormal rates of alanine aminotransferase, total protein, total bilirubin, and liver B-ultrasound in the exposure group were all higher than those in the control group, and the differences were statistically significant (&lt;i&gt;χ&lt;/i&gt;(2)=34.88, 42.49, 43.07, 55.28, &lt;i&gt;P&lt;/i&gt;&lt;0.001). Compared with the control group, the detected values of alanine aminotransferase, total protein and total bilirubin in the DMF exposure group were higher, and the difference was statistically significant (&lt;i&gt;F&lt;/i&gt;=5.367, 29.543, 37.766, &lt;i&gt;P&lt;/i&gt;&lt;0.05). In the DMF exposure group, the abnormal rates of liver function, electrocardiogram and liver B-ultrasound in men were much higher than those in women, and the differences were statistically significant (&lt;i&gt;χ&lt;/i&gt;(2)=185.05, 10.06, 141.94, &lt;i&gt;P&lt;/i&gt;&lt;0.001, &lt;i&gt;P&lt;/i&gt;=0.002, &lt;i&gt;P&lt;/i&gt;&lt;0.001). Grouped by length of service, the abnormal detection rate of liver function was similar in each length of service segment, and the difference was not statistically significant (&lt;i&gt;χ&lt;/i&gt;(2)=0.34, &lt;i&gt;P&lt;/i&gt;&gt;0.05). The abnormal detection rate of electrocardiogram increased with the increase of length of service, among which it was the highest in the 10-20 years of service, and the difference was statistically significant (&lt;i&gt;χ&lt;/i&gt;(2)=7.26, &lt;i&gt;P&lt;/i&gt;=0.026). The abnormal rate detected by liver B-ultrasound significantly increased with the increase of working years, and was the highest in the section of ≥20 years of working years. The difference was statistically significant (&lt;i&gt;χ&lt;/i&gt;(2)=44.15, &lt;i&gt;P&lt;/i&gt;&lt;0.001) . &lt;b&gt;Conclusion:&lt;/b&gt; Occupational exposure to DMF can affect the health of workers, especially increasing the detection rate of abnormal liver function and liver B-ultrasound. It is very important to strengthen the occupational health monitoring of personne","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"422-425"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study on occupational stress status and its effect on depressive symptoms and anxiety symptoms of workers from 14 electronic manufacturing enterprises in Qingdao].","authors":"F J Wang, F L Ji, Z Z Fu, M Y Gao, X W Dong, A Q Shi","doi":"10.3760/cma.j.cn121094-20240723-00339","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240723-00339","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the current status of occupational stress among electronic manufacturing workers in Qingdao and analyze its effect on depressive symptoms and anxiety symptoms. <b>Methods:</b> From July to September 2022, a cluster random sampling method was employed to select frontline workers from 14 electronic manufacturing enterprises in Qingdao as the study subjects. A total of 1134 questionnaires were distributed, with 1000 valid questionnaires collected, yielding an effective response rate of 88.18%. The Core Occupational Stress Scale (COSS), the Patient Health Questionnaire-9 (PHQ-9), and the Generalized Anxiety Disorder-7 (GAD-7) were adopted to assess occupational stress, depressive symptoms, and anxiety symptoms, respectively. Binary logistic regression was employed to analyze influencing factors of occupational stress and its effects on depressive and anxiety symptoms. <b>Results:</b> The detection rates of occupational stress, depressive symptoms, and anxiety symptoms were 15.1% (15/1000), 7.9% (79/1000), and 13.8% (138/1000), respectively. The influencing factor analysis of occupational stress revealed that female gender (<i>OR</i>=0.621, 95%<i>CI</i>: 0.434-0.890) and weekly working hours of 45-48 hours (<i>OR</i>=0.537, 95%<i>CI</i>: 0.309-0.935) were protective factors (<i>P</i><0.05), while weekly working hours ≥55 hours (<i>OR</i>=2.176, 95%<i>CI</i>: 1.290-3.670) and shift work (<i>OR</i>=2.038, 95%<i>CI</i>: 1.412-2.940) were risk factors (<i>P</i><0.05). Spearman correlation analysis showed that the COSS score was positively related with the PHQ-9 score and the GAD-7 score (<i>r</i>(s)=0.438, 0.289, <i>P</i><0.01). Workers judged with occupational stress had 3.596 times (95%<i>CI</i>: 2.181-5.931, <i>P</i><0.001) and 3.121 times (95%<i>CI</i>: 2.046-4.761, <i>P</i><0.001) higher risks of detecting depressive and anxiety symptoms compared to those without occupational stress. <b>Conclusion:</b> Electronic manufacturing workers in Qingdao experience a certain level of occupational stress, which may increase the risk of developing depressive and anxiety symptoms. Enterprises should implement appropriate interventions to promote workers' mental health.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"435-439"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of harmful status of 1, 2-Dichloroethane in the workplace of enterprises in a district of Chongqing].","authors":"C W Ran, Y Q Zhang, Q Liao, M J Liu, Y T Wen, Y Lei","doi":"10.3760/cma.j.cn121094-20240131-00044","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240131-00044","url":null,"abstract":"<p><p><b>Objective:</b> To Analysis of the current status of occupational hazard factors of 1, 2-dichloroethane (1, 2-DCE) in workplaces of enterprises in a certain district of Chongqing City, to provide a basis for its prevention and control. <b>Methods:</b> In January 2024, the monitoring data from the 2023 key occupational disease survey in the district were collected and organized. Qualitative analysis was conducted on the organic solvents used by enterprises in their production processes, and the detection results of 1, 2-DCE were statistically analyzed. <b>Results:</b> A total of 88 organic solvent samples were collected, with a qualitative detection rate of 21.6% (19/88) for 1, 2-DCE. A total of 30 enterprises using organic solvents were surveyed and tested, with an enterprise detection rate of 36.7% (11/30) for 1, 2-DCE. The workplace exceedance rate for 1, 2-DCE was 37.0% (34/92), and the post exceedance rate was 15.4% (4/26) . <b>Conclusion:</b> The degree of occupational exposure hazard related to 1, 2-DCE remains severe. It is necessary to strengthen the management of organic solvents used by enterprises and implement effective measures to prevent acute and chronic poisoning caused by 1, 2-DCE.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"469-471"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Investigation and analysis of occupational disease risk assessment index system in the automotive repair industry].","authors":"D X Li, K C Chen, M Zhang, S Ren","doi":"10.3760/cma.j.cn121094-20240515-00216","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240515-00216","url":null,"abstract":"<p><p><b>Objective:</b> To construct a risk assessment index system for occupational disease hazards in the automotive repair industry using the Delphi method, providing a scientific basis and systematic evaluation framework for occupational hazard management in this sector. <b>Methods:</b> In January 2024, an expert survey method was employed to identify occupational hazard risk indicators through in-depth expert discussions. A multidimensional and hierarchical assessment system was designed based on the two core elements of \"comprehensive prevention-on-site hazards.\" <b>Results:</b> The consultation results from 20 authoritative experts demonstrated that the expert authority coefficient (0.84), coordination coefficient (0.73), and reliability coefficient (0.83) all reached robust levels. The importance scores of the indicators (ranging from 3.47 to 5.59 points) exhibited clear discriminative validity. Ultimately, an assessment system comprising 2 first-level indicators, 5 second-level indicators, and 14 third-level indicators was established. <b>Conclusion:</b> The index system developed in this study demonstrates high scientific rigor and practical applicability. It provides a systematic evaluation tool for the hierarchical management and targeted prevention of occupational disease hazards in the automotive repair industry, offering both theoretical support and practical guidance for occupational hazard risk control in this field.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"426-429"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research on efficient ventilation protection measures for organic solvent in composite materials impregnation room].","authors":"X Y Nan, C Liu, R R Meng, Y F Xing, W X Du, Y J Wu","doi":"10.3760/cma.j.cn121094-20240407-00149","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240407-00149","url":null,"abstract":"<p><p><b>Objective:</b> To explore highly efficient ventilation protection technology for large-space workplaces adapted to the production process in composite material impregnation. <b>Methods:</b> A composite material impregnation room was selected as the research subject from August to December 2023. Occupational health investigation, on-site detection, and physical simulation of air distribution were used to analyze the distribution of the xylene concentrations in the impregnation room. In addition, the causes for excessive concentrations were analyzed, and the combination ventilation design of enclosed negative pressure cabinets and jet directional supply of fresh air was proposed. The concentration of xylene, the capture velocity and the differential pressure of ventilation facilities before and after the transformation were tested on the spot. The rationality of the airflow organization was determined through smoke testing, and the ventilation protection effects before and after the transformation were analyzed. <b>Results:</b> The time-weighted average allowable concentration (<i>C</i>(TWA)) of xylene was reduced from 41.73 mg/m(3) to 7.78 mg/m(3), and the <i>C</i>(TWA) of xylene were reduced by 81.4%. The values of capture velocity at all areas were higer than 0.5 m/s, and the values of velocity unevenness in all regions were lower than or equal to 0.25. The differential pressure between the enclosed cabinet and the impregnation room corridor was -2 to -1 Pa. The overall velocity distribution at all areas was relatively uniform, the airflow organization was reasonable, and negative pressure was formed inside the enclosed cabinet. <b>Conclusion:</b> The combination ventilation design of xylene, the capture velocity and the differential pressure of ventilation facilities effectively reducing the xylene concentration in the workplace, and provide a reference for ventilation protection of xylene workplace.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"417-421"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of a remote occupational health management model combining cluster management and individualized guidance in the treatment of pneumoconiosis].","authors":"L L Wang, X F Bai, Y P He, K J Jia","doi":"10.3760/cma.j.cn121094-20240227-00073","DOIUrl":"10.3760/cma.j.cn121094-20240227-00073","url":null,"abstract":"<p><p><b>Objective:</b> To explore the effects of the \"group+individual\" combined internet occupational health management model on the physiological indicators, pulmonary imaging changes and self-management ability of people with pneumoconiosis. <b>Methods:</b> In November 2022, patients diagnosed with pneumoconiosis in Baotou city from January 2012 to January 2022 were selected. Eighty cases exhibiting a decline in forcect expiratory volume in one second (FEV(1)) and pulmonary imaging changes (primarily ground-glass opacity variations) were chosen as study subjects. These patients were randomly divided into a control group and an experimental group using the sealed envelope method, with 40 patients in each group. The control group received conventional outpatient follow-up and occupational health surveillance management, while the experimental group underwent a remote occupational health management model combining \"group+individual\" approaches over 12 months, with interventions administered once every 3 months. Comparative analysis was conducted on pre-and pos-management indicators between the two groups, including pulmonary function, pulmonary imaging changes, and self-management ability scores. <b>Results:</b> After occupational health management, the experimental group showed superior improvement in observed indicators (including pulmonary function and pulmonary imaging indicators) compared to the control group (<i>P</i><0.05). The self-management ability scores of the experimental group after occupational health management were also better than those of the control group (all <i>P</i><0.05) . <b>Conclusion:</b> The remote occupational health management model combining group management and individualized guidance, when applied to patients with pneumoconiosis, is beneficial for improving their physiological indicators, pulmonary imaging indicators, and enhancing self-management abilities.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"440-444"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in biomarkers for delayed encephalopathy after acute carbon monoxide poisoning].","authors":"G L He, P Shen, M H Zhou","doi":"10.3760/cma.j.cn121094-20240411-00162","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240411-00162","url":null,"abstract":"<p><p>Acute carbon monoxide poisoning (ACMP) is a common harmful gas poisoning. Underwent systematic treatment and a 2-3 week pseudo-healing period, some ACMP patients may still develop delayed encephalopathy after acute carbon monoxide poisoning (DEACMP). DEACMP is the most severe complication that could happen to ACMP patients and comes with an exceeding high disability rate. Early identification and adequate intervention measures of DEACMP are particularly crucial for preventing its occurrence in clinical practice. At present, multiple studies have found that after ACMP occurred, a series of biomarkers showed predictive value for detecting the occurrence and development of DEACMP. This paper reviews these biomarkers and their predictive effects on DEACMP, aiming to provide theoretical guidance for the prevention and intervention of DEACMP.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"472-477"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of characteristics of carpal tunnel syndrome outpatients with complaints of \"numbness and pain in the hands\"].","authors":"Y M Zheng, S Q Li, D X Li, R J Ling, L Guan","doi":"10.3760/cma.j.cn121094-20240116-00020","DOIUrl":"https://doi.org/10.3760/cma.j.cn121094-20240116-00020","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the situation of outpatient patients diagnosed with carpal tunnel syndrome (CTS) due to typical hand symptoms and evaluate the diagnostic factors of CTS patients. <b>Methods:</b> Through an electronic medical record information system, a retrospective analysis was conducted on the data of outpatient patients diagnosed with CTS with \"numbness and pain in the hands\" as the complaints from January 1, 2018 to December 31, 2022 in eight medical institutions including Peking University Third Hospital, Third People's Hospital of Guizhou Province, Zhejiang Provincial People's Hospital Bijie Hospital, then the demographic characteristics and diagnostic factors such as symptoms, signs, and auxiliary examinations were analyzed. Chi-square test was used to compare the differences in CTS diagnosis rates between different genders and age groups. <b>Results:</b> There were a total of 43105 outpatients with complaints of \"numbness and pain in the hands\" over the past 5 years, of whom 754 were diagnosed with CTS, with a diagnostic rate of 1.7%. The there were 166 males and 588 females diagnosed with CTS, and the diagnostic rate of female patients was significantly higher than that of male patients (<i>χ</i>(2)=158.13, <i>P</i><0.001). Among the CTS patients, the proportion of patients aged 45 to 60 was the highest (43.8%, 330/754), and there was a statistically significant difference in CTS diagnosis rates among patients of different age groups (<i>χ</i>(2)=36.99, <i>P</i><0.001). All CTS patients had varying degrees of hand symptoms, and some had definite abnormalities in auxiliary examinations such as physical examination, wrist ultrasound, MRI or neuroelectrophysiology. <b>Conclusion:</b> The diagnosis rate of CTS among outpatients presenting with complaints of \"numbness and pain in the hands\" is relatively low, and there are gender and age distribution differences. In addition to typical clinical symptoms, the diagnosis of CTS also requires objective evidence from physical examination and further auxiliary examinations.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"43 6","pages":"449-452"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}