Zeitschrift für Naturforschung C最新文献_第2页

Frontmatter 头版头条

Zeitschrift für Naturforschung C Pub Date : 2023-07-01 DOI: 10.1515/znc-2023-frontmatter7-8

引用次数: 0

Frontmatter 头版头条

Zeitschrift für Naturforschung C Pub Date : 2023-05-01 DOI: 10.1515/znc-2023-frontmatter5-6

引用次数: 0

The search for commercial sweet white lupin (Lupinus albus L.) adaptive to Ethiopian growing condition seems not successful: what should be done? 寻找适合埃塞俄比亚生长条件的商业甜白罗苹(Lupinus albus L.)似乎不成功:应该做些什么?

Zeitschrift für Naturforschung C Pub Date : 2023-05-01 DOI: 10.2139/ssrn.4196861

L. Yeheyis, Wondimeneh Mekonnen, M. Nelson, David Mcnaughton, Alemu Tarekegn, Zelalem Yadelew, H. Sanders

{"title":"The search for commercial sweet white lupin (Lupinus albus L.) adaptive to Ethiopian growing condition seems not successful: what should be done?","authors":"L. Yeheyis, Wondimeneh Mekonnen, M. Nelson, David Mcnaughton, Alemu Tarekegn, Zelalem Yadelew, H. Sanders","doi":"10.2139/ssrn.4196861","DOIUrl":"https://doi.org/10.2139/ssrn.4196861","url":null,"abstract":"Abstract The study was conducted to find new adaptive commercial sweet white lupin (Lupinus albus L.) varieties and evaluate the effect of inoculum on herbage and seed yields of white and blue lupin varieties in Ethiopia for two growing seasons in two locations. For the experiment a factorial arrangement (seven variety * two inoculation) in a randomized complete block design with three replication was used. Three sweet blue (Bora, Sanabor and Vitabor), three sweet white (Dieta, Energy and Feodora) and one bitter white local landrace lupin varieties were tested in the experiment. Analysis of variance was done using the general linear model procedure in SAS. The effects of location and inoculum were insignificant (P ≥ 0.0761) on yield and yield parameters. The effect of variety was observed (P ≤ 0.035) only on plant height, fresh biomass yield and thousand seed weight in both seasons except for fresh biomass yield in season two. However, its effect on other parameters was not shown (P ≥ 0.134) in both growing seasons or only shown in either season. The mean dry matter yield of all varieties was 2.45 ton per ha. However, sweet blue entries performed better than white entries. The mean seed yield of blue sweet lupin entries and white local check was 2.6 ton per ha. Sweet blue and white local landrace varieties were found tolerant while, commercial sweet white lupin varieties were susceptible for anthracnose and fusarium diseases that occurred immediately after flowering. As a result imported commercial sweet white varieties failed to give seed yield. Developing adaptive, disease resistant and high yielding sweet white lupin through crossing the local and commercial varieties and looking for species specific inoculum should be the future research agendas.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"16 1","pages":"317 - 325"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74110777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Frontmatter 头版头条

Zeitschrift für Naturforschung C Pub Date : 2023-03-01 DOI: 10.1515/znc-2023-frontmatter3-4

引用次数: 0

Comparative study of phenolic profile, antioxidant and antimicrobial activities of aqueous extract of white and green tea 白茶和绿茶水提物酚类成分、抗氧化和抗菌活性的比较研究

Zeitschrift für Naturforschung C Pub Date : 2022-05-23 DOI: 10.1515/znc-2021-0321

Gamal A. Gabr, H. Hassan, V. Seshadri, N. Hassan

{"title":"Comparative study of phenolic profile, antioxidant and antimicrobial activities of aqueous extract of white and green tea","authors":"Gamal A. Gabr, H. Hassan, V. Seshadri, N. Hassan","doi":"10.1515/znc-2021-0321","DOIUrl":"https://doi.org/10.1515/znc-2021-0321","url":null,"abstract":"Abstract The sole difference between white tea (WT) and green tea (GT) is the former that made only from the buds and young leaves of the Camelia sinensis plant, whilst the latter is made from matured tea leaves. The phytochemical profiles, phenolic compounds, antioxidant, and antimicrobial activity of two varieties of Camellia sinensis teas, white and green, were compared in this study. Total antioxidant capacity, reducing power, DPPH radical scavenging, and Fe+2 chelating activities were used to determine antioxidant activities in water extract of GT and WT. The largest level of phenolic content was discovered in WGTE compared with the lowest amount was found in WWTE (290.67 mg/100 g tea and 185.96 mg/100 g tea, respectively). Phenoilc acids (gallic, benzoic, chlorogenic, ellagic, and ρ-coumaric acids) and flavonoids (rutin and kampherol) were found in the two extracts. The findings of DPPH radical scavenging assays were 84.06 and 82.37% inhibition. In vitro antimicrobial activity was indicated that (WWTE and WGTE) had a high level of activity against Staphylococcus aureus, and gave negative activity against Salmonella typhimurium, and Aspergillus Niger. The WT and GT extracts are a great source of natural antioxidants with biological effects on human health.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"13 1","pages":"483 - 492"},"PeriodicalIF":0.0,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81847732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis, characterization, molecular docking, dynamics simulations, and in silico absorption, distribution, metabolism, and excretion (ADME) studies of new thiazolylhydrazone derivatives as butyrylcholinesterase inhibitors 新型丁酰胆碱酯酶抑制剂噻唑酰腙衍生物的合成、表征、分子对接、动力学模拟及硅吸收、分布、代谢和排泄(ADME)研究

Zeitschrift für Naturforschung C Pub Date : 2022-05-23 DOI: 10.1515/znc-2021-0316

A. Işık, U. A. Çevik, I. Celik, Tuğba Erçetin, A. Koçak, Y. Özkay, Z. Kaplancıklı

{"title":"Synthesis, characterization, molecular docking, dynamics simulations, and in silico absorption, distribution, metabolism, and excretion (ADME) studies of new thiazolylhydrazone derivatives as butyrylcholinesterase inhibitors","authors":"A. Işık, U. A. Çevik, I. Celik, Tuğba Erçetin, A. Koçak, Y. Özkay, Z. Kaplancıklı","doi":"10.1515/znc-2021-0316","DOIUrl":"https://doi.org/10.1515/znc-2021-0316","url":null,"abstract":"Abstract In this study, two novel series of thiazolylhydrazone derivatives containing 4-ethylpiperazine (3a–3f) and 4-methoxyphenylpiperazine (3g–3l) side chains were synthesized and their structures were characterized by spectral (1H NMR, 13C NMR, and MS spectra) analyses. In vitro inhibitory activities of synthesized compounds against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were determined by Ellman method. According to the results, all compounds showed a weak inhibitory effect on AChE, while promising results were obtained on BChE. Among the synthesized compounds, the activities of the derivatives carrying 4-ethylpiperazine (3a–3f) structure were found to be more effective than the compounds carrying 4-methoxyphenyl piperazine (3g–3l) derivatives. Especially, compound 3f bearing the nitro substituent was found to be the most promising compound on BChE in the series. The absorption, distribution, metabolism, and excretion (ADME) parameters of the synthesized compounds were predicted by using the SwissADME server. The potential binding mode and stability of compound 3f with BChE were investigated by the molecular docking and dynamics simulations. The results showed that 3f was strongly bound up with BChE with the optimal conformation; in addition, their binding free energy reached −167.936 ± 13.109 kJ/mol.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"20 1","pages":"447 - 457"},"PeriodicalIF":0.0,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81525747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Frontmatter

Zeitschrift für Naturforschung C Pub Date : 2022-05-01 DOI: 10.1515/znc-2022-frontmatter5-6

引用次数: 0

Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds 吡啶基和三唑基噻唑类支架的合成、抗菌活性及模拟研究

Zeitschrift für Naturforschung C Pub Date : 2022-04-27 DOI: 10.1515/znc-2022-0002

Naime Funda Tay, B. Berk, M. Duran, I. Kayağil, L. Yurttaş, Sevde Nur Biltekin Kaleli, M. Yamaç, A. Karaduman, Ş. Demirayak

{"title":"Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds","authors":"Naime Funda Tay, B. Berk, M. Duran, I. Kayağil, L. Yurttaş, Sevde Nur Biltekin Kaleli, M. Yamaç, A. Karaduman, Ş. Demirayak","doi":"10.1515/znc-2022-0002","DOIUrl":"https://doi.org/10.1515/znc-2022-0002","url":null,"abstract":"Abstract In this study, novel 4-(5-((2/3/4-substituted benzyl)thio)-4-(4-substituted phenyl)-4H-1,2,4-triazol-3-yl)-2-(pyridin-3/4-yl)thiazoles were synthesized following a multi-step synthetic procedure. All the compounds were screened with a panel of gram positive/negative bacteria, yeasts, and molds for antimicrobial activity using the disc diffusion method. Then, the minimum inhibitor concentration (MIC) and the minimum bactericidal concentration (MBC) values of active compounds were determined against Micrococcus luteus, Bacillus cereus, Listeria monocytogenes, and Staphylococcus aureus using the broth microdilution technique. These compounds were also screened for their inhibitory activities against S. aureus DNA gyrase by supercoiling assay. Furthermore, the crystal structure of S. aureus DNA gyrase B ATPase was subjected to a docking experiment to identify the possible interactions between the most active ligand and the active site. Lastly, the in silico technique was performed to analyze and predict the drug-likeness, molecular and ADME properties of the synthesized molecules.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"36 1","pages":"429 - 446"},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74806599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Utilizing response surface methodology to evaluate the process parameters of indigenous cucumber fermentation 利用响应面法评价乡土黄瓜发酵工艺参数

Zeitschrift für Naturforschung C Pub Date : 2022-04-25 DOI: 10.1515/znc-2022-0009

H. Gül, M. Güngörmüşler

{"title":"Utilizing response surface methodology to evaluate the process parameters of indigenous cucumber fermentation","authors":"H. Gül, M. Güngörmüşler","doi":"10.1515/znc-2022-0009","DOIUrl":"https://doi.org/10.1515/znc-2022-0009","url":null,"abstract":"Abstract Commercial pickled cucumbers are produced in variety of salt concentrations including brines up to 15% sodium chloride due to the preventive nature of the salt towards microbial growth. Although it is deemed necessary for manufacturers to utilize high amounts of salts to prolong shelf life, the high content creates a burden for the growth of beneficial microorganisms including probiotics. In this study, the production of naturally fermented cucumbers and their microbial viability were tested with the help of an experimental design tool, Box-Behnken Design (BBD), to evaluate the optimal conditions for the production process and to maintain the highest viability of potential beneficial microorganisms during storage. Accordingly, the operational conditions including salt concentration (2, 5, or 8%), fermentation temperature (20, 25, or 30 °C), and brine filling (pretreatment) temperature (80, 85, or 90 °C) were optimized with a significant fit to a quadratic model (p < 0.05). The trends for sugar consumption and total acid production were monitored to demonstrate the correlation between the above-mentioned operational parameters for the fermentation process of pickled cucumbers with indigenous microorganisms. Overall, 5% salt content, 70 °C filling temperature and 25 °C fermentation medium was determined to maintain over 6 log cfu/mL viability. The results represent a valuable contribution to the pickle industry including a know-how of process parameters.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"58 1","pages":"417 - 427"},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85967217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-silico elucidation reveals potential phytochemicals against angiotensin-converting enzyme 2 (ACE-2) receptor to fight coronavirus disease 2019 (COVID-19) 芯片解析揭示了对抗血管紧张素转换酶2 (ACE-2)受体的潜在植物化学物质，以对抗2019冠状病毒病(COVID-19)

Zeitschrift für Naturforschung C Pub Date : 2022-04-25 DOI: 10.1515/znc-2021-0325

Hina Khalid, Sana Khalid, M. Sufyan, U. Ashfaq

引用次数: 1