World Journal of Pediatrics最新文献

{"title":"Guidelines for clean intermittent catheterization in children.","authors":"Zhao-Kai Zhou, Yi-Bo Wen, Qing-Wei Wang, Jian-Guo Wen, Stuart Bauer, Lillian C Hayes, Konstantinos Kamperis, Jens Christian Djurhuus, John Heesakkers, Tufan Tarcan, Giovanni Mosiello, Jane Clarke, Jennifer Sihoe","doi":"10.1007/s12519-025-01007-0","DOIUrl":"10.1007/s12519-025-01007-0","url":null,"abstract":"<p><strong>Background: </strong>Clean intermittent catheterization (CIC) is an effective method of bladder emptying in children with neurogenic and non-neurogenic disorders that cause difficulty in urination. However, there is a lack of expert consensus on the standardized application of CIC in pediatric populations. This guideline intends to outline recommendations for standardizing CIC in children.</p><p><strong>Methods: </strong>A comprehensive literature review was performed by searching key academic databases, specifically PubMed, Embase, the Cochrane Library, and Web of Science. Eligible literature-including peer-reviewed clinical trials, cohort studies, case series, and expert consensus statements-was systematically identified, screened, and critically appraised. This guideline was developed according to the \"WHO Handbook for Guideline Development (2nd edition)\".</p><p><strong>Results: </strong>For children with symptoms of increased post-void residual (PVR) that may threaten the upper urinary tract, CIC is recommended regardless of the cause. Safe bladder capacity (SBC) and maximum bladder capacity measurement could guide optimal CIC frequency. When infants or young children require CIC, their caregivers should receive specialized training. The CIC procedure includes thorough hand and genital area cleansing, followed by careful catheter insertion to avoid contamination of surrounding tissues. Depending on the individual's ability to void, CIC will be either partial or complete. Partial CIC is recommended for individuals who are able to void partially. When implementing CIC, a collaborative model involving the patient, caregivers, and a multidisciplinary pediatric team specializing in lower urinary tract management should be adopted, and regular follow-up and efficacy assessments are required. Urodynamic study to determine the PVR and SBC in conjunction with a voiding/catheterization diary provides an objective basis for adjusting the frequency of catheterization and for determining whether to continue catheterization.</p><p><strong>Conclusion: </strong>This guideline established a standardized protocol for children who require CIC to facilitate bladder emptying.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"404-423"},"PeriodicalIF":7.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of growth hormone therapy in adolescent short stature during late puberty: a prospective cohort study.","authors":"Ke Yuan, Yong-Hua Chen, Yan-Lan Fang, Xiao-Ming Ying, Jin-Ping Chen, Wei-Dong Su, Shun-Feng Mao, Jian-Ping Zhang, Qun-Hua Shen, Jian-Fang Zhu, Chun-Lin Wang","doi":"10.1007/s12519-026-01030-9","DOIUrl":"10.1007/s12519-026-01030-9","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"477-482"},"PeriodicalIF":7.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13221340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147639962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forgotten muscle: diaphragm and sudden infant death syndrome.","authors":"Pontus M Siren","doi":"10.1007/s12519-026-01026-5","DOIUrl":"10.1007/s12519-026-01026-5","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"389-397"},"PeriodicalIF":7.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13221364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-symptomatic treatment of spinal muscular atrophy: a strategic shift from concept to clinical practice.","authors":"Shan-Shan Mao","doi":"10.1007/s12519-026-01039-0","DOIUrl":"10.1007/s12519-026-01039-0","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"483-487"},"PeriodicalIF":7.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13221344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147875900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovations in pediatric imaging: a scoping review of the past decade with case illustrations.","authors":"Meinrad J Beer, Matthias C Schaal, Henning Neubauer","doi":"10.1007/s12519-026-01037-2","DOIUrl":"10.1007/s12519-026-01037-2","url":null,"abstract":"<p><strong>Background: </strong>Imaging plays a fundamental and increasing role in the diagnostic work-up of pediatric patients. Non-invasive imaging methods include ultrasonography, X-ray, computed tomography (CT), and magnetic resonance imaging (MRI). The importance of pediatric imaging is reflected in a large, and growing, body of scientific literature.</p><p><strong>Methods: </strong>A scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. MEDLINE (PubMed) was systematically searched in February 2025 for English-language original studies published between 2015 and 2025 in peer-reviewed journals. Additionally, illustrative cases from our institutional cohort were included to complement the review findings.</p><p><strong>Results: </strong>The presented scoping review demonstrates significant technical innovations in all explored imaging modalities. In ultrasonography, trauma imaging and contrast-enhanced ultrasound beyond voiding ultrasound are major areas of progress. X-ray and CT imaging in children benefit from improved radiation protection. Photon-counting CT has been introduced into routine clinical practice. Low-field, real-time, and CT-like MRI reduces the need for sedation and makes MRI faster, safer, and more accurate while opening new application possibilities. Finally, improvements in hybrid imaging [positron emission tomography (PET)/CT and PET/MRI], new contrast agents, and the implementation of advanced artificial intelligence techniques are pushing boundaries in diagnostic imaging.</p><p><strong>Conclusion: </strong>A decade of on-going technical innovation has provided interesting new tools for safer, faster, and more patient-centered clinical imaging studies in children and adolescents.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"424-434"},"PeriodicalIF":7.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13221362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147989415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extreme weather and pediatric respiratory health: insights from GINA 2025.","authors":"Peng Han, Kun-Ling Shen","doi":"10.1007/s12519-026-01033-6","DOIUrl":"10.1007/s12519-026-01033-6","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"398-403"},"PeriodicalIF":7.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human milk oligosaccharide supplementation for metabolic health and obesity: potential mechanisms, current evidence, and research priorities.","authors":"Kathryn Young, José G B Derraik, Benjamin B Albert, Mark H Vickers, Wayne S Cutfield","doi":"10.1007/s12519-026-01025-6","DOIUrl":"https://doi.org/10.1007/s12519-026-01025-6","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Jarvik 2015 ventricular assist device in a child with dilated cardiomyopathy and end-stage heart failure.","authors":"Ru Lin, Xiang-Ming Fan, Jing-Hua Ruan, Li-Yang Yin, Chun-Hong Xie, Song-Ling Fu, Shan-Shan Shi, Yun-Xiang Qiu, Jia-Jie Fan, Zi-Ying Jin, Jing-Jing Ye, Li-Jun Yang, Wen-Ting Zhao, Hang-Yan Zhao, Jun Zhou, Bu-Sheng Tian, Yu Chang, Kai-Yun Gu, Wei Wang, Shao-Qing Ni, Hai-Feng Chen, Adachi Iki, Xiang-Ming Fang, Qiang Shu","doi":"10.1007/s12519-026-01024-7","DOIUrl":"10.1007/s12519-026-01024-7","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"377-381"},"PeriodicalIF":7.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of pulmonary thromboembolism in children: an evidence-based expert consensus.","authors":"Li-Nan Zeng, Ying-Xue Zou, Hai-Lin Zhang, Li-Na Chen, De-Hui Chen, Xin-Xin Chen, Xing Chen, Zhi-Min Chen, Xiao-Yan Dong, Liang Huang, Yi Ji, Yong-Mei Jiang, Zhi-Ping Li, En-Mei Liu, Shu-Hua Luo, Xiao-Feng Ni, Guang-Min Nong, Yun Peng, Su-Yun Qian, Tian-You Wang, Xin-Yu Yuan, Hao Zhang, Hong Zhang, Xiao-Bo Zhang, De-Yu Zhao, Shun-Ying Zhao, Xiu-Fang Zhao, Kai-Yu Zhou, Quan Lu, Ling-Li Zhang, Han-Min Liu","doi":"10.1007/s12519-025-00987-3","DOIUrl":"10.1007/s12519-025-00987-3","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary thromboembolism is rare in children, but can be life-threatening. Timely diagnosis and treatment of pulmonary thromboembolism are crucial for reducing mortality associated with pulmonary thromboembolism in children. While guidelines for pulmonary thromboembolism in adults are available, guidelines for standardized diagnosis and management of pulmonary thromboembolism in children are not. This expert consensus aims to provide recommendations for the management of pulmonary thromboembolism in children based on the current best available evidence.</p><p><strong>Data sources: </strong>Following the World Health Organization Handbook for Guideline Development, the expert panel consisted of 30 members from different clinical areas. The panel identified clinical questions through systematic reviews and expert discussions, systematically reviewed evidence on pulmonary thromboembolism in children, and evaluated the quality of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Using the GRADE Evidence to Decision Framework, the panel made recommendations, considering the effects of interventions, resource use, values and preferences, equity, acceptability, and feasibility.</p><p><strong>Results: </strong>The epidemiology, classification, and pathophysiology characteristics are summarized. The expert panel developed 33 recommendations addressing 20 questions related to diagnosis steps, treatment approaches such as anticoagulant therapy, thrombolysis therapy, catheter-based interventional therapy, surgical embolectomy, multidisciplinary team, and treatment of patients with comorbidities, prognosis, education, as well as follow-up. Among these, 18 are weak recommendations based on very low quality evidence, and 15 are good practice statements.</p><p><strong>Conclusions: </strong>The expert panel provided recommendations for pulmonary thromboembolism in children based on available evidence, which was generally low in quality and volume. The panel urges further research on early identification and diagnosis strategies, preventive and therapeutic regimens, and long-term management for pulmonary thromboembolism.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"330-348"},"PeriodicalIF":7.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13076377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146258899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transition from childhood to adulthood care in celiac disease: an essential step.","authors":"Luís Sousa Barros, Sara Oliveira, Miguel Costa","doi":"10.1007/s12519-026-01018-5","DOIUrl":"10.1007/s12519-026-01018-5","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"277-280"},"PeriodicalIF":7.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146126514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}