World Journal of Pediatrics最新文献

{"title":"Systemic corticosteroid use and neurodevelopmental outcomes in preterm infants: a cohort study.","authors":"Adithya Shastry, Danish Ahmad, Alice Richardson, Barbara Bajuk, Traci-Anne Goyen, Pranav R Jani, Mohamed E Abdel-Latif","doi":"10.1007/s12519-025-00932-4","DOIUrl":"10.1007/s12519-025-00932-4","url":null,"abstract":"<p><strong>Background: </strong>The risk-benefit balance and safety of postnatal corticosteroid use for chronic lung disease (PNCSCLD) in preterm infants is a controversial matter. Our objective was to determine the trends in the use of PNCSCLD over eleven years and to analyze the neurodevelopmental consequences of PNCSCLD in preterm infants at 18-42 months of corrected age.</p><p><strong>Methods: </strong>The data for this retrospective population-based cohort study were obtained from ten tertiary neonatal intensive care units across New South Wales and the Australian Capital Territory, Australia. Preterm infants < 29⁺⁰ weeks' gestation born between January 1, 2007, and December 31, 2017, who were alive at discharge, without any major congenital anomalies were included and analyzed based on their PNCSCLD status.</p><p><strong>Results: </strong>Over eleven years, 611 (14.3%) out of 4258 infants received PNCSCLD. Among the 3386 eligible infants, 2636 (77.8%) underwent neurodevelopmental follow-up and were included in the final analysis. The rate of PNCSCLD use increased from 12.4% in 2007 to 19.6% in 2017. Similarly, the rate of moderate to severe functional disability (MSFD) increased from 8.8% in 2007 to 16.1% in 2017. Propensity-adjusted analysis revealed a greater odds ratio (OR) for MSFD in the PNCSCLD group than in the control group [average treatment effect: OR = 1.252, 95% confidence interval (CI) = 1.185-1.322, P ≤ 0.001; average treatment effect on the treated group: OR = 1.104, 95% CI = 1.031-1.184, P = 0.005].</p><p><strong>Conclusions: </strong>PNCSCLD use was associated with a greater incidence of MSFD. Clinicians should exercise caution when using PNCSCLD.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"575-586"},"PeriodicalIF":4.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative pain in children: an opioid-sparing perspective.","authors":"Ramón Eizaga Rebollar, Eduardo Manuel Lamadrid Castrillón, Carlos Chover Navarro, María Victoria García Palacios","doi":"10.1007/s12519-025-00925-3","DOIUrl":"10.1007/s12519-025-00925-3","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"542-549"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional relationship between child happiness and sleep quality and the predictive role of prenatal psychosocial support: results from U.S. and China cohort studies.","authors":"Ying Dai, Naixue Cui, Xiaopeng Ji, Adrian Raine, Therese S Richmond, Jianghong Liu","doi":"10.1007/s12519-025-00903-9","DOIUrl":"https://doi.org/10.1007/s12519-025-00903-9","url":null,"abstract":"<p><strong>Background: </strong>The relationship between daily affective states and subjective sleep measures is known to be reciprocal in both adults and children. However, its consistency across infancy to early adolescence and varying sociocultural contexts remain unclear. We investigated the bidirectional relationship between happiness and sleep quality in children from the U.S. and China and examined the predictive role of maternal prenatal psychosocial support.</p><p><strong>Methods: </strong>A total of 1300 children aged 11-12 years in the U.S. Healthy Brain and Behavior Study (HBBS) and China Jintan Child Cohort (CJCC) studies were included in the analyses. Happiness and sleep quality from infancy to early adolescence were retrospectively reported by mothers. Prenatal psychosocial factors were recalled by mothers through a structured interview. Random-intercept cross-lagged panel modeling was conducted to analyze the data.</p><p><strong>Results: </strong>Happiness and sleep quality trajectories differed significantly between U.S. adolescents in the HBBS and Chinese adolescents in the CJCC (P < 0.001). In both cohorts, cross-lagged effects showed consistent associations between happiness and subsequent sleep quality across the five time points (coefficients: 0.086-0.154, P < 0.01). The relationship between sleep quality and subsequent happiness was significant from 1-3 to 11 years. The bidirectional relationship was stronger in the Chinese cohort. Maternal prenatal psychosocial support positively predicted children's happiness (β = 0.072, P < 0.001) and sleep quality (β = 0.056, P < 0.001) trajectories.</p><p><strong>Conclusions: </strong>A bidirectional relationship exists between children's happiness and sleep quality, with potential cultural variations. Maternal prenatal psychosocial support plays a key role in fostering children's long-term emotional well-being and sleep quality.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and validity of the revised Chinese version of the Children's Sleep Habits Questionnaire (CSHQ-CH-R).","authors":"Yu-Jiao Deng, Tong Lin, Wen Li, Yan-Rui Jiang, Jing Zhang, Hui-Shan Wang, Hong Wang, Judith Owens, Guang-Hai Wang, Fan Jiang","doi":"10.1007/s12519-025-00915-5","DOIUrl":"https://doi.org/10.1007/s12519-025-00915-5","url":null,"abstract":"<p><strong>Background: </strong>The Chinese version of the Children's Sleep Habits Questionnaire (CSHQ-CH) has been widely used in clinical practice and research since it was developed in 2007. This study aimed to examine the psychometric properties of the revised version (CSHQ-CH-R) and establish cut-off values for screening for sleep disturbances in Chinese preschool-aged and school-aged children.</p><p><strong>Methods: </strong>A community sample of 3850 preschool and school-aged children aged 3-12 years were obtained from 6 kindergartens and 2 primary schools in Shanghai, Beijing and Chengdu, China, from December 2019 to February 2020. A clinical sample of 119 children aged 3-12 years who were diagnosed with sleep disorders were recruited from a tertiary pediatric hospital in Shanghai from September 2019 to November 2021. Caregivers completed the original 33 items of the CSHQ-CH plus an additional 15 items through an online platform. Item analysis was conducted to develop the CSHQ-CH-R, which included discriminative validity, redundancy and ambiguity. Internal consistency, interobserver reliability, test-retest reliability, concurrent validity (correlations with actigraphy) and discriminative validity were then analyzed. The cut-off values for both the full scale and subscale scores were generated by receiver operating characteristics.</p><p><strong>Results: </strong>The final version of the CSHQ-CH-R included 30 items and 8 subscales. Three subscales (bedtime resistance, sleep duration and daytime sleepiness) were revised, and the other five subscales were unchanged from those of the CSHQ-CH. The internal consistency for the full scale was 0.83 for the community sample, and 0.73 for the clinical sample. The internal consistency ranged from 0.47 (sleep duration) to 0.72 (bedtime resistance) for the community sample, and 0.38 (sleep duration) to 0.83 (sleep-disordered breathing) for the clinical sample. The interobserver reliability for the full scale was 0.55, and ranged from 0.38 (parasomnias) to 0.74 (bedtime resistance) for the subscales. The test-retest reliability was 0.70 for the full scale, and ranged from 0.54 (sleep duration) to 0.78 (bedtime resistance) for the subscales. Concurrent validities against actigraphy were 0.62 and 0.33 for \"time in bed\" and \"night sleep duration\", respectively. The clinical sample scored higher than the community sample did for the full scale and subscales (P < 0.01). A cut-off total score of 44 was determined, with an area under the curve of 0.76, a sensitivity of 0.64, and a specificity of 0.76. To facilitate cross-cultural comparisons, psychometric properties and cut-off values for the CSHQ-CH with the original 33 items were also provided.</p><p><strong>Conclusion: </strong>The CSHQ-CH-R exhibits satisfactory to good psychometric properties, indicating its suitability for identifying sleep problems among Chinese preschool- and school-aged children.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinopathy of prematurity in the era of precision neonatology: from risk stratification to targeted therapies.","authors":"Luca Filippi, Silvia Gulden, Maurizio Cammalleri, Gabriella Araimo, Giacomo Cavallaro, Eduardo Villamor","doi":"10.1007/s12519-025-00919-1","DOIUrl":"10.1007/s12519-025-00919-1","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"430-435"},"PeriodicalIF":6.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac magnetic resonance and genetics in pediatric heart failure patients with nonischemia: prognostic implications.","authors":"Xue-Lian Gao, Yan Chen, Kai-Rui Bo, Wen-Hong Ding, Chen-Cheng Dai, Yan-Yan Xiao, Lei Xu, Jian-Xiu Lian, Ling Han, Hui Wang","doi":"10.1007/s12519-025-00920-8","DOIUrl":"10.1007/s12519-025-00920-8","url":null,"abstract":"<p><strong>Background: </strong>The associations among genetic variants, cardiac magnetic resonance (CMR) features, and prognostic factors of pediatric heart failure (HF) remain unknown. This study aimed to explore the relationship between genetic differences in pediatric HF and CMR findings and their impact on prognosis of HF in children.</p><p><strong>Methods: </strong>This retrospective study included children with a first-time diagnosis of HF. All patients underwent echocardiogram, CMR and genetic testing. The cohort was divided into three subgroups according to late gadolinium enhancement (LGE) on CMR: the no LGE subgroup, the subendocardial LGE subgroup, and the nonsubendocardial subgroup. The endpoint was defined as a lack of improvement in HF on echocardiography after more than six months of follow-up.</p><p><strong>Results: </strong>Ninety-five children with HF were included, of whom 64 underwent genetic testing and 89 had echocardiograms at follow-up. There were 20 patients in the no LGE group, 31 in the subendocardial group, and 44 in the nonsubendocardial group. The most common genotype was MYH7 (27.0%). RBM20 and LMNA both presented a dilated phenotype, whereas GTPBP3 uniformly presented a hypertrophic phenotype. TNNI3 showed no LGE on CMR (P = 0.003) and maintained a restrictive phenotype. The subendocardial group was more likely to have septal LGE (93.5%, P < 0.001). Multivariable regression analysis indicated that a family history of cardiomyopathy, hydropericardium, and right ventricular ejection fraction (RVEF) were independent predictors of the endpoint event (P = 0.035, P = 0.005 and P = 0.032, respectively). Notably, nonsubendocardial LGE was associated with a worse prognosis than no LGE was (P = 0.030).</p><p><strong>Conclusions: </strong>In pediatric non-ischemic HF patients, subendocardial LGE can be observed. A family history of cardiomyopathy, hydropericardium, and RVEF were predictors of HF with no improvement. The prognosis of HF is associated with the presence of LGE, particularly nonsubendocardial LGE, and less so with the genetic phenotype.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"489-501"},"PeriodicalIF":4.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative therapies for childhood-onset systemic lupus erythematosus.","authors":"Dimitri Poddighe, Anh Thi Van Nguyen, Lan Tuyet Phung, Chi Quynh Le, Michelle Lynn Hermiston","doi":"10.1007/s12519-025-00913-7","DOIUrl":"10.1007/s12519-025-00913-7","url":null,"abstract":"","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"423-429"},"PeriodicalIF":6.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antenatal depressive and anxiety symptoms in early pregnancy and offspring allergic diseases during toddlerhood.","authors":"Jia-Ying Wu, Yi-Shu Wang, Yan-Hui Hao, Chen-Chi Duan, Yan Xu, Fang-Yue Zhou, Wen Yu, Li Xia, Ting Wu, Xuan-Ping Wang, Si-Wei Zhang, Si-Yue Chen, Xian Xia, Yan-Ting Wu, He-Feng Huang","doi":"10.1007/s12519-025-00911-9","DOIUrl":"10.1007/s12519-025-00911-9","url":null,"abstract":"<p><strong>Background: </strong>While maternal psychological stress during mid-to-late pregnancy has been linked to offspring allergies, the impact of early pregnancy distress remains unclear. This study investigates the association between maternal depressive and anxiety symptoms in early pregnancy and allergic diseases in offspring.</p><p><strong>Methods: </strong>Based on a birth cohort of 5263 children, antenatal depressive and anxiety symptoms in early pregnancy were assessed via the Patient Health Questionnaire and Generalized Anxiety Disorder Questionnaire, respectively. Allergic outcomes, including asthma, atopic dermatitis (AD), and allergic rhinitis (AR), were evaluated via structured questionnaires. Relative risks (RRs) with 95% confidence intervals (CIs) were estimated via generalized linear models, whereas restricted cubic splines were used to explore linear and non-linear associations between maternal distress and allergic outcomes.</p><p><strong>Results: </strong>Maternal depressive symptoms in early pregnancy were associated with an increased risk of AD [adjusted RR (95% CI) = 1.15 (1.03-1.29)] and AR [1.52 (1.29-1.79)]. Maternal anxiety symptoms in early pregnancy were associated with increased risks of AD [1.11 (1.02-1.21), mild anxiety] and AR [1.33 (1.04-1.68), moderate to severe anxiety]. Dose‒response analyses revealed graded relationships between distress severity and allergic outcomes. In the joint analysis, comorbid depression and anxiety in early pregnancy were associated with an increased risk of AD [1.15 (1.05-1.26)] and AR [1.42 (1.23-1.63)]. Subgroup analysis revealed a greater risk of asthma for boys born to mothers with mild anxiety [1.95 (1.20-3.15)] but not for girls.</p><p><strong>Conclusion: </strong>Maternal distress in early pregnancy is associated with an increased risk of allergic diseases in offspring during toddlerhood.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"478-488"},"PeriodicalIF":4.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the contributions of risk factors to under-five mortality in low- and lower-middle-income countries (1997-2022): an analysis of Demographic and Health Survey data.","authors":"Bereket Kefale, Jonine Jancey, Amanuel T Gebremedhin, Gavin Pereira, Gizachew A Tessema","doi":"10.1007/s12519-025-00912-8","DOIUrl":"10.1007/s12519-025-00912-8","url":null,"abstract":"<p><strong>Background: </strong>Under-five mortality (U5M) is a critical public health challenge in low- and lower-middle-income countries (LLMICs), where over 90% of global deaths occur. Despite progress, the changing contributions of risk factors to U5M in LLMICs remain unexplored.</p><p><strong>Methods: </strong>We analysed Demographic and Health Survey (DHS) data from 24 LLMICs across two periods: 1997-2005 and 2016-2022. We included 139,890 live births in 1997-2005 and 319,034 in 2016-2022. A mixed-effects robust Poisson regression model with a log link function was employed to identify risk factors of U5M in each period. Population-attributable fractions (PAFs) were calculated and compared to investigate changes in the contributions of risk factors over time.</p><p><strong>Results: </strong>U5M attributable to never having been breastfed increased by 15.5 percentage points (95% CI 8.6, 22.9), early maternal age at birth (< 20 years) by 5.4 percentage points (95% CI 3.1, 5.7), and plural births by 1.2 percentage points (95% CI 0.4, 1.8). U5M reductions attributable to maternal secondary education were increased by 5.5 percentage points (95% CI 0.4, 11.0) and tertiary education increased by 2.6 percentage points (95% CI 1.6, 4.2). However, U5M reductions associated with 1-3 antenatal care (ANC) visits decreased by 7.2 percentage points (95% CI 2.4, 11.7).</p><p><strong>Conclusions: </strong>The main contributors of U5M in LLMICs were never breastfeeding, short birth intervals (<33 months), ANC uptake, higher maternal education (secondary and tertiary), advanced maternal age at birth (≥35 years),  early maternal age at birth (<20 years), very small infants at birth, male sex, plurality, and single motherhood. The contributions of risk factors to U5M have changed over time. Interventions need to prioritise promoting breastfeeding, enhancing maternal education and increasing ANC uptake, and addressing other significant contributors to U5M.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"502-514"},"PeriodicalIF":4.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12167716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the respiratory chain enzyme activity in peripheral blood monocytes for the noninvasive diagnostics of mitochondrial disease.","authors":"Jing-Jing Liu, Si-Min Wang, Zi-Han Zhang, Xue-Qian Wang, Xiao-Hui Zhang, Hong-Ying Wang, Ting Chen","doi":"10.1007/s12519-025-00918-2","DOIUrl":"10.1007/s12519-025-00918-2","url":null,"abstract":"<p><strong>Background: </strong>Mitochondrial diseases are among the most common metabolic disorders caused by mitochondrial dysfunction. Analyzing mitochondrial respiratory chain enzyme activity is essential for diagnosis. However, clinical laboratories often rely on mitochondria isolated from muscle biopsies or cultured skin fibroblasts, which may be unacceptable for some pediatric patients. This highlights the need for improved blood-based diagnostic methods.</p><p><strong>Methods: </strong>This paper describes spectrophotometric assays to evaluate mitochondrial respiratory chain enzyme activity in peripheral blood monocytes. Sample preparation methods and assays for respiratory complexes I-IV and the mitochondrial matrix enzyme citrate synthase are detailed. The assays were validated via samples from a panel of 28 healthy children and validated in patients with combined and isolated mitochondrial oxidative phosphorylation system (OXPHOS) deficiency.</p><p><strong>Results: </strong>The citrate synthase-normalized activities were 0.23 ± 0.08 for complex I, 0.22 ± 0.081 for complex II, 0.16 ± 0.07 for complex III, and 0.22 ± 0.07 for complex IV. All patients with mitochondrial disease exhibited the expected reductions in respiratory complex activity.</p><p><strong>Conclusions: </strong>We established a method to analyze the respiratory complex activities via blood samples. The normal enzymatic activity ranges were established from healthy Chinese pediatric populations. We also validated the assay via samples from patients with mitochondrial disease. By establishing the first pediatric-specific reference ranges for mitochondrial respiratory chain complex activities in a Chinese population and validating this minimally invasive blood-based assay in patients with mitochondrial disease, our study enabled earlier detection, precise monitoring, and personalized management of mitochondrial disorders while avoiding the need for invasive tissue biopsies.</p>","PeriodicalId":23883,"journal":{"name":"World Journal of Pediatrics","volume":" ","pages":"515-524"},"PeriodicalIF":4.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}