Benjamin D Reynolds, Cameron J Whittaker, Kelly A Caruso, William M Irving, Paul M McCarthy, Jeffrey S Smith
{"title":"Treating Evaporative Dry Eye Disease in Dogs Based Upon Tear Film Lipid-Layer Thickness: A Retrospective Cohort Study.","authors":"Benjamin D Reynolds, Cameron J Whittaker, Kelly A Caruso, William M Irving, Paul M McCarthy, Jeffrey S Smith","doi":"10.1111/vop.70079","DOIUrl":"https://doi.org/10.1111/vop.70079","url":null,"abstract":"<p><strong>Objective: </strong>To classify evaporative dry eye disease (EDED) in dogs and trial therapies based upon tear film lipid layer thickness.</p><p><strong>Animals: </strong>Twenty client-owned dogs diagnosed with EDED.</p><p><strong>Procedures: </strong>Patients were recruited for retrospective assessment if they were diagnosed with EDED in the absence of other diagnoses that may lead to tear film instability. Tear film interferometry was performed to diagnose a lipid-deficient EDED (LD-EDED; < 30 nm) or idiopathic EDED (I-EDED; > 30 nm). Dogs with LD-EDED were treated with combined topical paraffin and wool fat ointment and oral flaxseed oil. Dogs with I-EDED were treated with combined topical trehalose and hyaluronic acid drops and either topical compounded tacrolimus or cyclosporine. A TFBUT was performed a minimum of 4 weeks later, and these were compared pre- and posttreatment via paired student t-tests and linear regression analysis with Pearson's correlations.</p><p><strong>Results: </strong>Patients with LD-EDED had a significant and strong correlation between pretreatment lipid layer thickness and pretreatment TFBUT (p = 0.037). Total mean pre- and posttreatment TFBUT was 3.63 ± 2.48 and 10.79 ± 4.83 s (p < 0.001) seconds, respectively (p < 0.001). LD-EDED pre- and posttreatment TFBUT was 3.75 ± 3.05 s and 11.75 ± 3.98 s (p < 0.001), respectively (p < 0.001). Patients with I-EDED had a pre- and posttreatment TFBUT of 3.56 ± 2.63 s and 9.76 ± 4.32 s, respectively (p < 0.001).</p><p><strong>Conclusion: </strong>Dogs with EDED appear to have significantly longer TFBUT following directed therapy.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Transcorneal Iris Photocoagulation to Facilitate Sector Iridectomy of Pigmented Iridal Tumors: A Case Series of Five Eyes (Three Dogs and One Cat)-Clinical Findings, Surgical Technique, Complications, and Outcome.","authors":"A K Shukla, P Grest, N Holz, A Rampazzo, S A Pot","doi":"10.1111/vop.70076","DOIUrl":"https://doi.org/10.1111/vop.70076","url":null,"abstract":"<p><strong>Objective: </strong>To describe the use of transcorneal iris photocoagulation (TCIP) to improve intraocular visualization of intended incision lines, reduce hemorrhage, and facilitate excision of pigmented iridal tumors in four canine eyes and one feline eye.</p><p><strong>Materials and methods: </strong>A Rhodesian Ridgeback (treated bilaterally), a German Shepherd, a Labrador Retriever, and a Scottish Fold underwent sector iridectomy due to rapidly growing, pigmented, raised, iridal tumors affecting 1/4-1/3 of the iris circumference (3- to 4-clock hours). A diode laser was used to delineate the intended sector iridectomy incision lines, approximately 1-2 mm away from the grossly visible tumor margins, with the aim of improving visualization to achieve tumor-free margins and reduce tissue handling/trauma.</p><p><strong>Results: </strong>All iridal tumors were removed en bloc with tumor-free margins on histopathology. The most common histologic diagnosis was iris melanocytoma (3/5 eyes). The most common intra- and postoperative complications included hyphema and fibrin clot formation (5/5), posterior synechia formation of iris wound margins (5/5 eyes), and photophobia (3/5 eyes). Two eyes required intracameral tissue plasminogen activator (tPA) injections within 2 weeks of surgery. The follow-up period for all operated eyes ranged from 5 to 14 months. Vision was retained in all eyes, with no grossly apparent tumor regrowth within the follow-up times included for each case in the present series.</p><p><strong>Conclusions: </strong>The use of TCIP to delineate intended incision lines improved intraocular visualization of sector iridectomy surgical margins in this case series. While hyphema and fibrin clot formation still occurred, they were successfully managed.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noah M Plotsker, Ryan Taylor, Hannah R Coffin, April Beatty, Georgina Newbold, Kelly E Knickelbein
{"title":"Equine Sarcoid Arising From the Medial Caruncle With Invasion of the Third Eyelid in a Quarter Horse Gelding.","authors":"Noah M Plotsker, Ryan Taylor, Hannah R Coffin, April Beatty, Georgina Newbold, Kelly E Knickelbein","doi":"10.1111/vop.70074","DOIUrl":"https://doi.org/10.1111/vop.70074","url":null,"abstract":"<p><strong>Objective: </strong>To describe the clinical and histologic features of a sarcoid arising from the medial caruncle with spread to the third eyelid of a horse.</p><p><strong>Animal studied: </strong>A 20-year-old Quarter Horse gelding.</p><p><strong>Procedures: </strong>An incisional biopsy of the medial caruncle mass was initially performed, with histopathology suggesting a sarcoid or other spindle cell neoplasm. The mass grew rapidly following the biopsy, expanding to affect the third eyelid and adjacent superior palpebral conjunctiva. A complete third eyelid and medial caruncle excision with resection of affected palpebral conjunctiva and adjunctive cryotherapy was subsequently performed.</p><p><strong>Results: </strong>Histopathology revealed the mass to be consistent with an equine sarcoid as evidenced by a densely cellular population of neoplastic spindle cells arranged into interlacing bundles with collagenous stroma and with hyperplastic overlying epithelium extending into the neoplasm as thin rete ridges. Over 90% of neoplastic cells showed strong hybridization signaling for bovine papillomavirus types 1 and 2, supporting an underlying viral cause consistent with the diagnosis of a sarcoid.</p><p><strong>Conclusions: </strong>This paper describes the first reported case of an equine sarcoid arising from the medial caruncle with spread to the third eyelid, treated with third eyelid and medial caruncle excision and adjunctive cryotherapy. Veterinarians evaluating horses with masses affecting the medial caruncle and third eyelid should consider sarcoids as a differential diagnosis. Rapid growth of cutaneous sarcoids following incisional biopsy is common, and the same may be true for sarcoids that arise from the medial caruncle or third eyelid.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Luisa Perez Orrico, Mikel Sabater Gonzalez, Jessica Villar Ibañez, Javier Planas Escudero, Kinley Smith, Rodrigo Pinheiro de Lacerda, Samuela Mazzucchelli
{"title":"Intraocular Pressure Reference Values Comparing Two Rebound Tonometers (TonoVet and TonoVet Plus) in Male Camels (Camelus dromedarius).","authors":"Maria Luisa Perez Orrico, Mikel Sabater Gonzalez, Jessica Villar Ibañez, Javier Planas Escudero, Kinley Smith, Rodrigo Pinheiro de Lacerda, Samuela Mazzucchelli","doi":"10.1111/vop.13327","DOIUrl":"10.1111/vop.13327","url":null,"abstract":"<p><strong>Objective: </strong>To determine the intraocular pressure (IOP) reference values in healthy male camels using two rebound tonometers: TonoVet (TV) and TonoVet Plus (TV+), and to compare measurements between both devices and in different body positions.</p><p><strong>Animals' studied: </strong>Thirty-four healthy, captive, adult (8-24 years and a median age of 14), male camels belonging to a zoological collection in Fuerteventura, Spain.</p><p><strong>Methods: </strong>All camels underwent general physical examination, slit lamp biomicroscopy, and tonometry, under minimal physical restraint (headstall and chute). Three consecutive readings were acquired with TV and/or TV+ in the right and/or left eyes in standing and/or sitting positions, whenever possible. Comparisons between groups were made when paired data for the test variable was available for the same eye (for tonometer and body position) or for the same animal (for left and right eyes) using paired t-tests.</p><p><strong>Results: </strong>The mean IOP (± standard error and range) in standing position was 18.51 mmHg (0.52, 10.33-24.33 mmHg) for TV and 19.53 mmHg (0.50, 12.33-26.33 mmHg) for TV+. In sitting position, the IOP was 14.70 mmHg (0.49, 11.33-18.33 mmHg) for TV and 16.28 mmHg (0.47, 13-19.66 mmHg) for TV+. Measurements for both TV and TV+ were significantly higher (p = 0.003 and p = 0.011, respectively) in standing position. Recordings with TV+ were significantly higher than with TV, in any body position (p < 0.001 and p = 0.006, respectively). There were no statistically significant differences between right and left eyes, except for TV+ in standing position, with the IOP in the left eye being significantly higher (20.58 mmHg versus 18.51 mmHg, p = 0.004).</p><p><strong>Conclusions: </strong>To the authors' knowledge, this is the first report estimating the IOP reference values in male camels comparing two different rebound tonometers. Measurements for both TV and TV+ were significantly higher in the standing position. Recordings with TV+ were significantly higher than with TV (in any body position). Further studies with female individuals and different age groups are warranted.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"855-861"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia Busse, Anne Raab, Lothar Kreienbrock, Holger Andreas Volk
{"title":"Insights from an online survey: Veterinary surgeons' antibiotic practices in ophthalmic surgery in Germany.","authors":"Claudia Busse, Anne Raab, Lothar Kreienbrock, Holger Andreas Volk","doi":"10.1111/vop.13300","DOIUrl":"10.1111/vop.13300","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate antibiotic usage practices in ophthalmic surgeries in Germany.</p><p><strong>Materials and methods: </strong>An online questionnaire was sent to veterinary surgeons (general veterinarians and veterinarians with additional qualification in ophthalmology) inquiring about their antibiotic preferences, administration methods, and factors affecting antibiotic usage in ophthalmic surgical procedures.</p><p><strong>Results: </strong>A total of 417 questionnaires were analyzed. Postoperative antibiotics (systemic/topical in percent when used) were used all or most of the time by 69% of veterinarians following enucleation (99/6), by 62% after eyelid surgery (54/69), by 68% after third eyelid (TEL) surgery (19/92) and by 80% after keratectomy (6/99). The most commonly used systemic antibiotic was amoxicillin with clavulanic acid and the most commonly used topical antibiotic was chloramphenicol. WHO \"watch-group\" antibiotics were infrequently administered systemically but frequently utilized topically; including in 13% of eyelid surgery, 15% of TEL surgery, and 35% of keratectomies. Factors influencing antibiotic use included fear of complications (67%), personal experience (63%), diagnostic uncertainty (21%), and owner expectations (9%). Participants following institutional guidelines used fewer antibiotics in enucleations (p = .002) and were less likely to choose fluoroquinolones post-eyelid surgery (p = .044).</p><p><strong>Conclusion: </strong>The potential for reducing antibiotic use following ophthalmic soft tissue surgery is significant. Addressing barriers such as concerns about postoperative complications and the reliance on individual clinical experience, the implementation of standardized guidelines could facilitate a shift toward more judicious antibiotic practices.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"820-829"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes.","authors":"Sophie Hofmann-Wellenhof, Barbara Nell","doi":"10.1111/vop.13301","DOIUrl":"10.1111/vop.13301","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to inform about the clinical image, diagnostic possibilities, and treatment options for cats and dogs diagnosed with ocular encephalitozoonosis.</p><p><strong>Materials and methods: </strong>Medical records of 7 dogs and 75 cats with ocular encephalitozoonosis presented at the Clinical Unit of Ophthalmology of the University of Veterinary Medicine Vienna between 08/2006 and 02/2022 have been compiled. Diagnosis was based on the presence of cataracts and positive antibody titer against Encephalitozoon cuniculi. Patient history, details on the characteristics of the cataracts, level of antibody titers, and the treatment regimen were summarized, as are the results of histological stainings of surgical samples to determine the presence of Encephalitozoon cuniculi, as well as PCR analyses to identify its sub-strains.</p><p><strong>Results: </strong>Our analysis of the clinical data shows that focal cortical anterior cataracts often associated with anterior uveitis and lesions in the fundus are the most prevalent manifestation of ocular encephalitozoonosis in cats and dogs.</p><p><strong>Conclusion: </strong>Serological testing and PCR analysis of lens material are the most important diagnostic tools. Timely phacoemulsification with adjuvant anti-inflammatory and antiparasitic medication is the most promising therapy for Encephalitozoon cuniculi-induced cataracts.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"830-846"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ocular Abnormalities in 127 Cats Presented for Companion Animal Eye Registry (CAER) Examination in the United States and Canada.","authors":"Emma C Collins, Kathryn A Diehl","doi":"10.1111/vop.70067","DOIUrl":"10.1111/vop.70067","url":null,"abstract":"<p><strong>Study objective: </strong>To investigate the prevalence and clinical appearance of ocular abnormalities in a US and Canadian population of cats registered with the Companion Animal Eye Registry (CAER) between 2013 and 2023.</p><p><strong>Methods: </strong>All complete (131) feline CAER exam forms from 2013 to 2023 in the OFA database, were reviewed. Available pedigrees of cats included in this study were also investigated. The central tendencies and dispersion data were reported.</p><p><strong>Results: </strong>The population consisted of 113 Bengal, six British Shorthair, two each Maine Coon, and Norwegian Forest, and one each Domestic Shorthair, Ragamuffin, Siberian, and Sphynx cats. Four cats had serial CAER examinations performed. Twenty-two (20%) Bengal cats had normal ophthalmic exams, and 91 (80%) had abnormalities noted. Eighty-one (72%) of the Bengal cats had cataract(s) noted, of which the characteristics varied widely.</p><p><strong>Discussion: </strong>Suggestive of a possible hereditary basis, there was a high prevalence of young Bengal cats presented for CAER examinations between 2013 and 20233 that had functionally incidental cataracts that were expected to be essentially nonprogressive. Most of the noted feline cataracts were bilateral, symmetric, punctate or incipient, and nuclear or posterior. Very minimal pedigree information received supported a possible hereditary basis of cataracts among the British Shorthair cats, but was insufficient to confirm this or apply to the entire study population.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"862-865"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majbritt M E Larsen, Anna Eriksson, Joseph A Impellizeri
{"title":"Electrochemotherapy with bleomycin for bilateral ocular squamous cell carcinoma in a horse.","authors":"Majbritt M E Larsen, Anna Eriksson, Joseph A Impellizeri","doi":"10.1111/vop.13310","DOIUrl":"10.1111/vop.13310","url":null,"abstract":"<p><strong>Objective: </strong>To describe the procedure and outcome of electrochemotherapy (ECT) with bleomycin as a first-line treatment for bilateral ocular surface squamous neoplasia (OSSN) in the eye of a horse.</p><p><strong>Animal studied: </strong>A client-owned 5-year-old Haflinger gelding with limbal-conjunctival squamous cell carcinoma.</p><p><strong>Procedures: </strong>During general and local anesthesia, injection of bleomycin in the ocular tumor was followed by electroporation, applied with a 15 mm needle electrode, needles held parallel to the ocular surface.</p><p><strong>Results: </strong>Treatment with ECT resulted in therapeutic electric pulses and complete tumor response with no recurrence during follow-up. Tumor toxicity as a result of treatment was mild, with no adverse effect to normal tissue.</p><p><strong>Conclusions: </strong>In this case of bilateral ocular tumors, staged ECT with bleomycin was shown to be a safe and effective treatment with complete tumor remission and no recurrence during the observation period. The result suggests ECT as a possible treatment in ocular tumors, with further research recommended.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"886-892"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Keratoconjunctivitis sicca in intact Aksaray Malakli breed dogs: Evaluation of 50 cases.","authors":"Nihan Avci, Fehmiye Gumus, Basak Boztok Ozgermen, Dogukan Ozen","doi":"10.1111/vop.13298","DOIUrl":"10.1111/vop.13298","url":null,"abstract":"<p><strong>Objectives: </strong>Keratoconjunctivitis sicca (KCS) is characterized by decreased aqueous tear film components, leading to ocular surface damage. Diagnosis involves clinical examination, Schirmer Tear Test (STT1), and Tear Film Break-Up Time (TFBUT) measurement. This retrospective study aimed to assess dry eye syndrome in intact, purebred, Aksaray Malakli breed dogs, and investigate potential associations with hereditary ocular diseases due to inbreeding for phenotype preservation.</p><p><strong>Animals: </strong>Fifty healthy, purebred, intact Aksaray Malakli dogs of varying ages and sexes, all exhibiting conjunctival hyperemia and mucoid ocular discharge. Dogs with chronic diseases, systemic medication, or ongoing ophthalmic treatment were excluded.</p><p><strong>Procedures: </strong>Demographic data, ophthalmic examination results, and ocular anomalies were recorded. STT1 and TFBUT assessments were performed to measure tear production and film stability. STT1 values were scored from 1 (normal) to 4 (severe dry eye), and TFBUT ≥20 s was considered normal. Statistical analyses were used to evaluate correlations and differences.</p><p><strong>Results: </strong>The correlation between age and STT1 values (r = -.182, p = .206) was not statistically significant. Mean STT1 was higher in females than males, though not significantly (p = .849). Dogs without third eyelid gland prolapse had significantly higher STT1 and TFBUT measurements compared to those with prolapse (p = .027). No significant sex difference was found in the frequency of third eyelid prolapse (p = .289). A significant positive correlation was observed between STT1 and TFBUT (r = .924; p < .001).</p><p><strong>Conclusions: </strong>Aksaray Malakli dogs, particularly those with third eyelid gland prolapse, are predisposed to mild to moderate KCS. These findings suggest the need for further clinical and genetic investigations to better understand and manage dry eye syndrome in this breed.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"802-811"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phillip N Buckman, Bailey A Brinker, Lydia E Kapeller, András M Komáromy
{"title":"Validation of the EYEMATE-SC Suprachoroidal Pressure Transducer for Telemetric Measurement of Intraocular Pressure in Normal Ex Vivo Canine and Equine Globes-Preliminary Results.","authors":"Phillip N Buckman, Bailey A Brinker, Lydia E Kapeller, András M Komáromy","doi":"10.1111/vop.70071","DOIUrl":"10.1111/vop.70071","url":null,"abstract":"<p><strong>Objective: </strong>To determine the accuracy of the EYEMATE-SC suprachoroidal tracer for telemetric tonometry in canine and equine globes.</p><p><strong>Procedures: </strong>The EYEMATE-SC sensor (7.8 mm × 3.8 mm × 1 mm) was implanted in the suprachoroidal space of four freshly enucleated normal canine and two normal equine eyes. The anterior chambers were cannulated and connected to a reservoir of Plasma-Lyte A and a manometer. Starting at a manometric IOP of 5 mmHg, the pressure was progressively increased to 80 mmHg by raising the reservoir. At each setpoint (5, 10, 15, 20, 25, 30, 35, 40, 50, 60, 70, and 80 mmHg), triplicate telemetric measurements were taken with the EYEMATE-SC using a portable reading device for telemetric pressure transmission via a radiofrequency band. These measurements were compared to manometric pressure by linear regression analysis.</p><p><strong>Results: </strong>A strong positive linear regression was observed between EYEMATE-SC and manometry IOPs in both canine and equine eyes (canine: R<sup>2</sup> = 0.99; equine: R<sup>2</sup> = 0.99). The EYEMATE-SC was unable to measure pressures > 70 mmHg in either species.</p><p><strong>Conclusions: </strong>Measuring canine and equine IOPs from the suprachoroidal space using the EYEMATE-SC provided accurate results over an extensive range of pressures in ex vivo globes. This telemetric sensor could assist with long-term, frequent tonometry by pet owners and clinicians following in vivo testing. Although the sensor could not detect pressures above 70 mmHg, this flaw was not considered clinically relevant.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"866-870"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}