Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B最新文献

{"title":"[Total beta activity in teeth of cattle of various age groups].","authors":"W. Giese, K. Harry, W. Prinz","doi":"10.1111/J.1439-0450.1965.TB01431.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1965.TB01431.X","url":null,"abstract":"Zusammenfassung \u0000 \u0000Radioaktivitatsmessungen an Schneidezahnen von 380 Rindern aus dem norddeutschen Raum ergaben bei hoherem Zahnalter geringere Meswerte an β-Aktivitat pro g Calcium. Ein Vergleich von Mesergebnissen der in dem Zeitraum 1953–1963 herangebildeten Zahne mit den Durchschnittswerten fur Strontium90 pro l Milch in den entsprechenden Jahren zeigte eine statistisch zu sichernde Korrelation der beiden Radioaktivitatskurven. Daran wird die Abhangigkeit des Radioaktivitat-Gehaltes des Zahnes von der jeweils herrschenden Falloutsituation zur Zeit seiner Formierung verdeutlicht, wobei unbedenklich vorausgesetzt werden kann, das der groste Teil der radioaktiven β-Strahlung von Strontium90 im Zahn herruhrt. Ein Vergleich mit den in Menschenzahnen gefundenen Werten last erkennen, das in Rinderzahnen eine ungleich hohere β-Aktivitat pro g Calcium vorliegt als beim Menschen. \u0000 \u0000 \u0000 \u0000Summary \u0000 \u0000The total beta activity in the teeth of cattle of different ages \u0000 \u0000 \u0000 \u0000Measurements of radioactivity of the incisor teeth of 380 cattle in Northern Germany showed that older animals had lower beta activity per gramme of calcium. A comparison of the values for teeth produced between 1953 and 1963 with the mean values for strontium 90 per litre of milk in the corresponding years showed a statistically significant correlation in the radioactivity curves. This shows the dependence of the radioactivity of teeth on the fall-out situation at the time of their formation and makes it certain that most of the beta radiation comes from strontium 90 in the teeth. Comparison with human teeth shows that the beta activity per gramme of calcium is slightly higher in cattle. \u0000 \u0000 \u0000 \u0000Resume \u0000 \u0000La radio-activite β totale dans les dents de bovins appartenant a differents groupes d'âge \u0000 \u0000 \u0000 \u0000Des mesures de la radio-activite des incisives de 380 bovins provenant d'Allemagne du nord montrerent chez les animaux les plus âges des valeurs plus faibles de radio-activite β par gramme de Ca. Une comparaison des resultats entre les dents ayant cru entre 1953 et 1963 et les valeurs moyennes de strontium 90 par litre de lait dans les annees correspondantes montra une correlation statistiquement significative entre les deux courbes de radio-activite. Par consequent, la dependance de la teneur des dents en elements radio-actifs des retombees existant au moment de leur formation se trouve mise en evidence, et il peut etre admis sans hesiter que la plus grande partie de la radiation β provient du strontium 90 contenu dans les dents. Une comparaison avec les valeurs trouvees dans les dents humaines montre une radio-activite nettement plus grande dans les dents bovines que chez l'homme. \u0000 \u0000 \u0000 \u0000Resumen \u0000 \u0000La actividad β total en dientes de bovinos de diferentes grupos de edad \u0000 \u0000 \u0000 \u0000Mediciones de la radiactividad efectuadas en dientes incisivos de 380 bovidos de la region septentrional alemana evidenciaron en edades dentales mayores unos valores de mensuracion menores en actividad β por g de cal","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"33 1","pages":"587-91"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76951984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Is swine plague pathogenetically an allergic disease?].","authors":"W. Bisping","doi":"10.1111/J.1439-0450.1965.TB01391.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1965.TB01391.X","url":null,"abstract":"Zusammenfassung \u0000 \u0000Die Pathogenese der akuten und chronischen Schweinepest glaubt Korn aufgrund eigener Beobachtungen und experimenteller Untersuchungen als einen immunpathologischen Vorgang im Sinne der Allergielehre deuten zu konnen. Es werden Gegengrunde dargelegt, die aufzeigen sollen, das unsere derzeitigen wissenschaftlichen Erkenntnisse ebenso wie die Untersuchungsergebnisse von Korn fur eine derartige Betrachtungsweise keine uberzeugenden Anhaltspunkte liefern. Die Vermutung Korns uber die Mitwirkung der Allergie beim Zustandekommen der Schweinepest kann hochstens als Hypothese gewertet werden, die wissenschaftlich nichts beweist und daruber hinaus auch nur wenig Wahrscheinlichkeit fur sich hat. \u0000 \u0000 \u0000 \u0000Summary \u0000 \u0000Has swine fever an allergic pathogenesis? \u0000 \u0000 \u0000 \u0000In two papers published in 1964 Korn, on the basis of his own observations and experimental studies, considered that the pathogenesis of acute and cronic swine fever represents an immuno-pathological process of allergic nature. The author counters this view in the light of his own experience and also the results quoted by Korn and considers that the view put forward by Korn that allergy plays a part in bringing about swine fever is purely hypothetical, has no scientific backing and is most improbable. \u0000 \u0000 \u0000 \u0000Resume \u0000 \u0000La peste porcine est-elle, du point de vue de la pathogenie, une maladie allergique? \u0000 \u0000 \u0000 \u0000Sur la base d'observations personelles et de recherches experimentales, Korn croit pouvoir interpreter la pathogenie de la peste porcine aigue et chronique comme un processus de la pathologie de l'immunite comme un phenomene allergique. L'auteur presente ici des contre-arguments ayant pour but de montrer que nos connaissances scientifiques actuelles, tant d'ailleurs que les resultats des recherches de Korn ne sauraient soutenir d'une maniere convaincante une telle facon de voir. L'opinion de Korn concernant la contribution de phenomenes allergiques a la genese de la peste porcine peut tout au plus etre consideree comme une hypothese qui ne prouve rien scientifiquement et n'offre en outre que tres peu de vraisemblance. \u0000 \u0000 \u0000 \u0000Resumen \u0000 \u0000?Es la peste porcina patogenicamente una alergosis? \u0000 \u0000 \u0000 \u0000Korn cree poder interpretar la patogenia de la peste porcina aguda y cronica como un proceso inmunopatologico en el sentido de la alergologia, fundandose en observaciones propias y en estudios experimentales. Se aportan razones contrarias que deben esclarecer que nuestros conocimientos actuales y los resultados experimentales de Korn que justifiquen una forma semejante de reflexionar no ofrecen puntos de referencia convincentes. La conjetura de Korn sobre la cooperacion de la alergia en la institucion de la peste porcina puede valorarse a lo sumo como hipotesis, que desde el punto de vista cientifico nada demuestra y, por encima de esto, apenas tiene probabilidades a su favor.","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"40 1","pages":"268-77"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73811440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Studies on the pathogenesis of aleutian mink disease. V. Immunofluorescent microscopical findings in the kidney].","authors":"G. Trautwein, D. Seidler","doi":"10.1111/J.1439-0450.1972.TB00388.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1972.TB00388.X","url":null,"abstract":"","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"56 1","pages":"144-57"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77864015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Behavior of Trypanosoma evansi under the influence of diacetyl-N2-guanyl-N2(p-amidinophenyl)-dihydrazone-dihydrochloride].","authors":"J. Holz","doi":"10.1111/J.1439-0450.1965.TB01374.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1965.TB01374.X","url":null,"abstract":"Zusammenfassung \u0000 \u0000Trypanosoma evansi wurde 2½ Jahre unter Einflus von Diacethyl-N2-guanyl-N2-(p-amidinophenyl)-dihydrazon-dihydrochlorid gehalten. Die Parasiten wurden im Laufe der Zeit weniger virulent gegen die Wirte (Meerschweinchen), resistenter im Bezug auf das Therapeutikum; gleichzeitig wurden die Einzeller formmasig kurzer. \u0000 \u0000 \u0000 \u0000Summary \u0000 \u0000The behaviour of Trypanosoma evansi under the influence of Diacethyl-N2-guanyl-N2-(p. amidinophenyl)-dihydrazonedihydrochloride \u0000 \u0000 \u0000 \u0000T. evansi was kept for 2½ years under the influence of this drug. During this time the parasite became less virulent for the host (guinea pig) and more resistant to the therapeutic agent. Simultaneously the protozoa developed a shorter form. \u0000 \u0000 \u0000 \u0000Resume \u0000 \u0000Comportement du trypanosoma evansi sous l'influence du dihydrochlorure de diacothyl-N2-guanyl-N2-(p-amidinophenyl)-dihydrazone \u0000 \u0000 \u0000 \u0000Trypanosoma evansi a ete conserve pendant 2 ans et demi sous l'influence du dihydrochlorure de diacothyl-N2-guanyl-N2-(p-amidinophenyle)-dihydrazone. En cours de temps, les parasites ont perdu de leur virulence pour leurs hotes (cobayes) et sont devenus plus resistants au therapeutique; simultanement les protozoaires devenaient de forme plus courte. \u0000 \u0000 \u0000 \u0000Resumen \u0000 \u0000Comportamiento del Trypanosoma evansi bajo influjo del diclorhidrato de la diacotil-N2-guanil-N2-(p-amidinofenil)-dihidrazona \u0000 \u0000 \u0000 \u0000El Trypanosoma evansi se mantuvo durante 2 anos y medio bajo influjo del diclorhidrato de la diacotil-N2-guanil-N2-(p-amidinofenil)-dihidrazona. En el curso del tiempo, los parasitos se tornaron menos virulentos frente a los anfitriones (cobayas) y mas resistentes frente al farmaco; al mismo tiempo adoptaron estos parasitos unicelulares una forma mas corta.","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"264 6 1","pages":"67-73"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77016190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The immune peroxidase method for demonstration of viral and chlamydia antigens. 3. Demonstration of TGE-virus antigen in porcine thyroid gland cell cultures].","authors":"W. Becker, P. Teufel, W. Mields","doi":"10.1111/J.1439-0450.1974.TB00467.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1974.TB00467.X","url":null,"abstract":"","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"1 1","pages":"59-65"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82202520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Studies on antibiotic food additives on the resistance development of coliforme intestinal flora in pigs. 1. Feeding experiments with terramycin and chloramphenicol].","authors":"K. Beyer, E. Bulling, G. Godglück, R. Stephan","doi":"10.1111/J.1439-0450.1971.TB01611.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1971.TB01611.X","url":null,"abstract":"","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"11 1","pages":"385-95"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75609855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Length of daylight and oxytetracycline plasma level in laying hens following therapeutic administration of oxytetracycline in food].","authors":"K. Hinz, K. Lai, H. Lüders","doi":"10.1111/J.1439-0450.1972.TB00383.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1972.TB00383.X","url":null,"abstract":"Summary \u0000 \u0000Length of daylight and oxytetracycline plasma level in laying hens given therapeutic doses of oxytetracycline in the food \u0000 \u0000 \u0000 \u0000Using the gel diffusion test, the plasma level of oxytetracycline was measured at intervals in laying hens given oxytetracycline in the food and receiving 9 and 17 hours of artificial lighting. When 700 ppm of OTC was given in the food it was only possible to reach and maintain a minimal plasma therapeutic level of 0.5 mcg./OTC/ml. over a period of several days by adding potentiating substances (terephthalic acid) to the food and reducing its calcium content. \u0000 \u0000 \u0000 \u0000The largest amounts of OTC per unit of time were ingested by the laying hens before the end of a period of artificial illumination, independently of the length of the illuminated day. The maximal OTC plasma levels also occurred just before or after the end of a period of illumination. \u0000 \u0000 \u0000 \u0000The ingestion of medicaments is limited by periods of illumination. One should take account of the effects of this illumination on the blood tissue levels when applying drugs therapeutically in the food and water. \u0000 \u0000 \u0000 \u0000Resume \u0000 \u0000Duree d'illumination et taux de l'oxytetracycline dans le plasma sanguin chez des pondeuses, apres administration d'oxytetracycline en doses therapeutiques dans l'aliment \u0000 \u0000 \u0000 \u0000On determine a differents moments, a l'aide du test de diffusion en gelose, le taux d'oxytetracycline dans le plasma sanguin chez des pondeuses ayant ingere librement de l'aliment contenant de l'oxytetracycline, pendant 9 et 17 heures d'illumination artificielle. Lorsque l'on administre 700 ppm de OTC par l'aliment, on n'aitteint et on ne maintient la valeur minimum de 0,5 mcg OTC/ml, consideree comme therapeutiquement active, chez les animaux d'experience, qu'en plusieurs jours et apres adjonction de substances potentialisantes (acide terephtalique) a l'aliment et reduction du calcium alimentaire. \u0000 \u0000 \u0000 \u0000Les pondeuses ingerent toujours les quantites de OTC les plus elevees par unite de temps avant la fin d'une periode d'illumination artificielle, independante de la lumiere du jour. On observe egalement les valeurs maximums de OTC dans le plasma sanguin dans le laps de temps avant ou apres la fin d'une periode d'illumination. \u0000 \u0000 \u0000 \u0000L'ingestion des medicaments est limitee par les periodes d'illumination. Il faudrait tenir davantage compte des effets de cette limitation sur le taux sanguin et tissulaire, dans l'application therapeutique de medicaments par l'aliment et l'eau d'abreuvage. \u0000 \u0000 \u0000 \u0000Resumen \u0000 \u0000Longitud de la luz dial y el nivel de oxitetraciclina en el plasma sanguineo de gallinas ponedoras despues de la administracion de oxitetraciclina en dosis terapeuticas con el pienso \u0000 \u0000 \u0000 \u0000En momentos diferentes se valoraron en la prueba de placas horadadas de agar los niveles del plasma sanguineo de gallinas ponedoras, las cuales se iluminaban nueve y 17 horas con luz artificial, pudiendo ingerir oxitetraciclina libremente con el pienso. Al administrar 700 p","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"38 1","pages":"99-110"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76466304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Studies on intra- and interspecies relationships of bacterial hemolysins. 1. Identification of marked and masking toxin relationships of Cl. perfringens. Efficiency of the serum-unmasking test for the diagnosis of the classical C-subtype].","authors":"D. Marica, W. Klemm, C. Vasiu","doi":"10.1111/J.1439-0450.1975.TB00580.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1975.TB00580.X","url":null,"abstract":"","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"188 1","pages":"196-204"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73184800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental transplacental transmission of hog cholera virus in pigs. V. Immunopathological findings in newborn pigs.","authors":"W. Hermanns, G. Trautwein, H. Meyer, B. Liess","doi":"10.1111/J.1439-0450.1981.TB01789.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1981.TB01789.X","url":null,"abstract":"Summary \u0000 \u0000Intranasal exposure of gilts to hog cholera virus strain “GLENTORF” on the 65th and 67th day of gestation resulted within 43–47 days in 30 or more per cent fetal mortality. The vast majority of fetuses born alive by hysterotomy shortly before term were shown to be viremic while the sera did not show any neutralizing activity. Exposure of gilts on the 85th day of gestation under otherwise similar conditions led to infection of the fetuses as demonstrated by the detection of viral antigen in a few fetuses but not to virus isolation und to the development of neutralizing antibody detectable again in only a few fetuses. The intervals between exposure of the gilts and hysterotomy was 25–26 days only and therefore much shorter than in the former group of experimental animals. Mortality amongst the fetuses was not observed in gilts exposed between the 94th and 101th day of gestation. Demonstration of neutralizing antibody in 2 out of 44 sera and detection of viral antigen in the spleen of 4 out of 45 fetuses without infectious virus being found indicates transplacental transmission of HC virus within a period of 13 to 18 days after exposure of the gilts. \u0000 \u0000 \u0000 \u0000According to these results the 65th to 67th day of gestation appeared to be the latest date for the establishment of persistent viremia which would last beyond term. The 85th day seems to be too late for the virus to reach the fetuses in a state of immunotolerance although considerable individual differences might exist within the same litter. \u0000 \u0000 \u0000 \u0000Zusammenfassung \u0000 \u0000Experimentelle transplazentare Ubertragung des Virus der Europaischen Schweinepest in Schweine I. Virologische und serologische Untersuchungen \u0000 \u0000 \u0000 \u0000Die intranasale Exposition von tragenden Sauen am 65. bis 67. Tag der Trachtigkeit gegenuber dem Schweinepestvirus Stamm “GLENTORF” fuhrte innerhalb von 43 bis 47 Tagen zu einer fetalen Mortalitat von 30 und mehr Prozent. Es konnte nachgewiesen werden, das die lebend per Hysterektomie kurz vor dem Termin geborenen Feten weit in der Mehrzahl eine Viramie, ihre Seren keine virusneutralisierende Aktivitat aufwiesen. Auf die Exposition der tragenden Sauen am 85. Trachtigkeitstag unter sonst ahnlichen Bedingungen folgte eine Infektion der Feten, die durch den Nachweis von Virusantigen bei einigen Feten, nicht aber mittels Virusisolierung nachweisbar war, und die Bildung neutralisierender Antikorper nachweisbar ebenfalls nur bei wenigen Feten. Hier betrug der Zeitraum zwischen Exposition der Sauen und Hysterektomie nur 25 bis 26 Tage und war damit wesentlich kurzer als bei der vorgenannten Versuchstiergruppe. Bei tragenden Sauen am 94. bis 101. Tag der Trachtigkeit wurden nach Exposition keine fetalen Todesfalle festgestellt. Der Nachweis von neutralisierenden Antikorpern bei 2 von 44 fetalen Seren und von Virusantigen in der Milz bei 4 von 45 Feten, ohne das eine Virusisolierung gelang, zeigt auf, das das Schweinepestvirus in einer Zeitspanne von 13–18 Tagen nach der Exposition ","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"73 1","pages":"669-83"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86273196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Studies on so-called radiotoxins].","authors":"A. Schmid, K. Zipf, K. Gutschow","doi":"10.1111/J.1439-0450.1965.TB01427.X","DOIUrl":"https://doi.org/10.1111/J.1439-0450.1965.TB01427.X","url":null,"abstract":"Zusammenfassung \u0000 \u0000Rattenserum von Spendertieren, welche Ganzkorperdosen von 150, 500, 1000 und 5000 rad einer kupfergefilterten 60 kV-Rontgenstrahlung erhalten hatten, wurde an unbehandelte Ratten sc verabreicht. In den folgenden 8 Stunden zeigte die Gesamtleukozytenzahl im stromenden Blut der Empfangertiere folgendes Verhalten: \u0000 \u0000 \u0000 \u0000Spenderserum nach 150 und 500 rad verursachte eine starkere, Serum nach 1000 und 5000 rad eine schwachere Depression als Normalserum; \u0000 \u0000 \u0000 \u0000Spenderserum nach 150 und 500, nicht aber nach 1000 und 5000 rad loste “Pulsationen” ahnlich jenen nach Ganzkorperapplikation kleiner Strahlendosen (s. vorhergehende Arbeit) aus. \u0000 \u0000 \u0000 \u0000Die “paradoxe Reaktion” der Gesamtleukozytenzahl nach den hoheren Empfangerdosen wird diskutiert. \u0000 \u0000 \u0000 \u0000Summary \u0000 \u0000Studies on so-called radiotoxins \u0000 \u0000 \u0000 \u0000Untreated rats were given doses of serum from donor rats given wholebody doses of 150, 500, 1,000 and 5,000 rads of copper-filtered 60 kV X-rays. In the following eight hours the leucocyte picture showed: \u0000 \u0000 \u0000 \u00001. Donor serum after 150 to 500 rads caused a more marked depression and serum after 1,000 and 5,000 rads a less marked depression than normal serum. \u0000 \u0000 \u0000 \u00002. Serum from animals given 150 and 500 rads, but not from those given 1,000 and 5,000 rads produced pulsations similar to those produced by wholebody irradiation with small doses (see preceding paper). \u0000 \u0000 \u0000 \u0000The paradoxical reaction of the leucocyte count after large doses is discussed. \u0000 \u0000 \u0000 \u0000Resume \u0000 \u0000Recherches sur les «radiotoxines« \u0000 \u0000 \u0000 \u0000Du serum d'animaux donneurs ayant subit des doses de 150, 500, 1000 et 5000 rads en irradiation corporelle totale par un appareil a rayons × avec filtration au cuivre de 60 kV fut administre par voie sous-cutanee a des rats non traites. Dans les 8 heures suivantes, le nombre total des leucocytes presentait dans le sang peripherique des animaux recepteurs des variations rapportees ci-dessous. \u0000 \u0000 \u0000 \u0000Le serum de donneurs ayant subi une radiation de 150 et 500 rads provoquait une depression plus grande que le serum normal, tandis que le serum des rats irradies par 1000 et 5000 rads entrainait une depression plus faible. \u0000 \u0000 \u0000 \u0000Le serum des donneurs apres irradiation par 150 et 500 rads (mais pas 1000 et 5000 rads) provoquait des pulsations analogues a celle qui suit l'irradiation corporelle totale par des petites doses de radiation (voir travail precedent). Les auteurs discutent les causes possibles de la reaction paradoxale du nombre total des leucocytes apres l'application d'une dose elevee de rayons. \u0000 \u0000 \u0000 \u0000Resumen \u0000 \u0000Estudios sobre las llamadas radiotoxinas \u0000 \u0000 \u0000 \u0000El suero de ratas donantes, que habian recibido dosis corporales de 150, 500, 1000 y 5000 rad de una radiacion roentgenologica de 60 kV filtrada por cobre, se administro por via sc a ratas no pretratadas. Durante las 8 horas subsiguientes, la cifra leucocitica total en sangre circulante de los animales receptores ofrecio el comportamiento siguiente: \u0000 \u0000 \u0000 \u0000el suero donante oca","PeriodicalId":23829,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","volume":"10 1","pages":"567-70"},"PeriodicalIF":0.0,"publicationDate":"2010-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84300537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}