{"title":"One Case of Refractory Condyloma Acuminatum in Children with Persistent HPV51 Infection Treated By Chinese Medicine Paiteling","authors":"Meng Yang, Yaohui Huang, Qing-guo Zhu, Xing Lin, Yanbin Pan, Jianmin Li","doi":"10.23937/2469-5750/1510079","DOIUrl":"https://doi.org/10.23937/2469-5750/1510079","url":null,"abstract":"A 3-year-old female presented with neoplasms on the perianal for1 month. Physical examination:Multiple needle tips appearing around the anus to millet size. A few vegetations are seen at the vaginal opening. Human papilloma virus (HPV) typing: HPV51 positive. HIV, TPPA, and RPR tests were negative. Histopathology of skin lesions: hyperkeratosis of the epidermis with incomplete keratosis, hyperplasia and hypertrophy of the spinous layer, papilloma-like hyperplasia, vacuolated cells seen above the spinal layer; Diagnosis: Condyloma acuminatum. Treatment: 4 times of photodynamic therapy was ineffective, HPV-51 continued to be positive, and then switched to the Chinese medicine Paiteling three-stage therapy. No new warts were found after follow-up for 1 year, and the HPV-51 turned negative.","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130589777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Study of the Online Over-The-Counter Hair Loss Products","authors":"Alyoussef Abdullah","doi":"10.23937/2469-5750/1510077","DOIUrl":"https://doi.org/10.23937/2469-5750/1510077","url":null,"abstract":"Background: There are tremendous amount of the overthe-counter (OTC) hair loss products available online and widely purchase all over the world by many consumers. We conducted this study to evaluate some popular and widely used OTC hair loss products that are introduced by famous online retailer websites. Methods: We identified the top selling hair loss products using data introduced by some online retailers such as Amazon, Etsy, Bonanza and Overstock. All products data were obtained from the retailers’ websites and were compared for their type and active ingredients. Results: Most of hair loss products are natural products, vitamins, minerals, amino acids and proteins. The products found in the top sellers are different between the online retailers regarding their type, side, dosage forms and prices. Minoxidil, the only FDA approved OTC hair loss drug, is found only in the list of top seller of Amazon.com. Conclusions: Many of the OTC hair loss treatments were natural products with very few evidences about their efficacy. The OTC hair loss products nearly costs the same as the FDA approved drug, minoxidil.","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128044203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angel Medina Andrade Luis, Andrade Laura Guadalupe Medina, López Lizbeth Elisa Oropeza, Valencia Andrea Marianne Rodriguez, Romero Haizel Valencia, Piña Angel Adrian Moreno, Chaparro Araceli Esteban, Hernández Alberto Robles Méndez
{"title":"Hyperchromic and Erythematous Pityriasis: Case Report and Review of the Literature","authors":"Angel Medina Andrade Luis, Andrade Laura Guadalupe Medina, López Lizbeth Elisa Oropeza, Valencia Andrea Marianne Rodriguez, Romero Haizel Valencia, Piña Angel Adrian Moreno, Chaparro Araceli Esteban, Hernández Alberto Robles Méndez","doi":"10.23937/2469-5750/1510073","DOIUrl":"https://doi.org/10.23937/2469-5750/1510073","url":null,"abstract":"Pityriasis versicolor is a superficial fungal infection of the skin, characterized by pigmentary changes secondary to the colonization of the stratum corneum by a lipophilic dimorphic fungus known as Malassezia sp. Of this genus, 7 species known as the causative agent of pityriasis versicolor, the most frequently isolated species is M. Globosa. This skin disease occurs worldwide but predominates in the tropical, warm, and humid climate. Malassezia sp classified as dimorphic fungi since it behaves as yeast in crops but is capable of producing filaments in its parasitic form. It comes with numerous hyper, hypochromic or erythematous macules, covered with fine flake that converges to form plaques of different morphologies. The most frequent topography is the trunk, the shoulders, and chest in front and back. The diagnosis is clinical, but a mycological study with direct examination must be done. Clusters of rounded or oval yeast clusters are found also fragmented short and thick filaments. The treatment is divided between specific and nonspecific antifungal agents. Recurrences are frequent, up from 60% in the first year and 80% in the second year, so it should be emphasized general measures of treatment.","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114463679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Niema, N. Aicha, Gallouj Salim, Mernissi Fatima Zahra
{"title":"Nail Disorders in Patients with Chronic Renal Failure","authors":"A. Niema, N. Aicha, Gallouj Salim, Mernissi Fatima Zahra","doi":"10.23937/2469-5750/1510065","DOIUrl":"https://doi.org/10.23937/2469-5750/1510065","url":null,"abstract":"Background: Ungual manifestations occurring in patients with end stage renal failure are polymorphic and diverse. The aim of our study was to assess the prevalence and characteristics of different ungual manifestations in patients end stage renal failure. Patients and methods: We led a transverse investigation of all patients with end stage renal failure followed in the department of nephrology of University Hospital Hassan II, during a period of three months from 01 August 2016 to 01 November 2016. Results: We examined 70 patients (34 men and 36 women). The renal failure duration ranged from 6 months to 13 years. A total of 56/70 (80%) patients had ungual abnormalities. These included absence of lunula, half and half nails, splinter hemorrhages, melanonychia, onycholysis, Beau’s lines, koilonychias and Muehrcke lines, onychomycosis, pincer-nail deformity, brittle nails and onychogryphosis, leukonychia, longitudinal ridging, subungual hyperkeratosis, paronychia, nail clubbing. Our results find no significant relationship between the ungual disorders and patient age or duration of renal failure. Conclusion: Our study found different nail changes in uraemic patients, these abnormalities varied from the most frequent (onycholysis) to rare conditions such as nail clubbing.","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115347807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case of Th2 Cytokines in a Japanese Girl Who Acquired Hookworm-Related Cutaneous Larva","authors":"Kondo Makoto, Yamanaka Keiichi","doi":"10.23937/2469-5750/1510064","DOIUrl":"https://doi.org/10.23937/2469-5750/1510064","url":null,"abstract":"Interleukin (IL)-18 cascade-mediated mechanism is deeply involved in host defense against parasitic infections both in vivo and in vitro. A patient who acquired hookworm-related cutaneous larva migrans (HrCLM) in Pattaya, Thailand, was investigated for the transition of serum Th2 cytokines. A 5-year-old healthy girl had walked barefoot on a beach in Pattaya, Thailand. After returning to Japan, linear red nodules appeared on her foot plantar and dorsum. Although the parasite remained undetected in a surgery, she was administered oral ivermectin twice at 1-week interval. Her eosinophil count, immunoglobulin (Ig) E level, and serum immune-related Th2 cytokine levels (IL-3, IL-4, IL-5, IL-13, IL-18, and IL-33) were sequentially measured. The IL-18 cascade was found to be largely involved in HrCLM. IL-18 and IL-13 exerted an anthelmintic action along with increased eosinophil counts.","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"431 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116230200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
González Maria del Carmen Pantín, Giménez Diego Malón, Vila Beatriz Losada, Pascual Beatriz Antón, Abad David Gutiérrez, Baños Nadia Sánchez, C. Sánchez
Lahrichi A, Hali F, Baline K, Marnissi F, Chiheb S
{"title":"Lupus Miliaris Disseminatus Faciei Treated By Isotretinoin and Platelet Rich Plasma","authors":"Lahrichi A, Hali F, Baline K, Marnissi F, Chiheb S","doi":"10.23937/2469-5750/1510072","DOIUrl":"https://doi.org/10.23937/2469-5750/1510072","url":null,"abstract":"","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129797949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Test, C. Ferreli, Ángela María, L. Atzori, L. Pilloni, F. Rongioletti
{"title":"Axillary Fox-Fordyce Disease Induced By Laser Hair Removal","authors":"E. Test, C. Ferreli, Ángela María, L. Atzori, L. Pilloni, F. Rongioletti","doi":"10.23937/2469-5750/1510071","DOIUrl":"https://doi.org/10.23937/2469-5750/1510071","url":null,"abstract":"Fox-Fordyce disease (FFD) is an uncommon chronic inflammatory skin disease of the apocrine sweat glands that could be considered as a rare adverse event of laser hair removal. It is postulated that laser therapy could induce damage to the follicular infundibulum, resulting in epidermal detachment and altered keratinocytes maturation which led to keratin plugging. Here, we present a case of a post-pubertal woman who developed axillary itchy lesions with clinical and histological features compatible with FFD, after a series of axillary laser hair removal treatments. The management of the condition is unsatisfying: We suggested our patient stopping epilation sessions and applying topical corticosteroids, with good response on symptoms but no significant effect on the lesions.","PeriodicalId":237664,"journal":{"name":"Journal of Dermatology Research and Therapy","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115963166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}