Nail Disorders in Patients with Chronic Renal Failure

Background: Ungual manifestations occurring in patients with end stage renal failure are polymorphic and diverse. The aim of our study was to assess the prevalence and characteristics of different ungual manifestations in patients end stage renal failure. Patients and methods: We led a transverse investigation of all patients with end stage renal failure followed in the department of nephrology of University Hospital Hassan II, during a period of three months from 01 August 2016 to 01 November 2016. Results: We examined 70 patients (34 men and 36 women). The renal failure duration ranged from 6 months to 13 years. A total of 56/70 (80%) patients had ungual abnormalities. These included absence of lunula, half and half nails, splinter hemorrhages, melanonychia, onycholysis, Beau’s lines, koilonychias and Muehrcke lines, onychomycosis, pincer-nail deformity, brittle nails and onychogryphosis, leukonychia, longitudinal ridging, subungual hyperkeratosis, paronychia, nail clubbing. Our results find no significant relationship between the ungual disorders and patient age or duration of renal failure. Conclusion: Our study found different nail changes in uraemic patients, these abnormalities varied from the most frequent (onycholysis) to rare conditions such as nail clubbing.