Veterinary Surgery最新文献

{"title":"Accuracy of fluoroscopy-guided osteotomy placement in TPLO: Postoperative tibial plateau angle and preoperative planning evaluation.","authors":"Rita Y Wang, Trenton J Stephens, Samuel D Stewart","doi":"10.1111/vsu.14295","DOIUrl":"https://doi.org/10.1111/vsu.14295","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the accuracy of achieving a predetermined postoperative tibial plateau angle (TPA) using fluoroscopy-assisted osteotomy planning and positioning, and to assess the reproducibility of preoperative tibial plateau leveling osteotomy (TPLO) radiographic measurements intraoperatively.</p><p><strong>Study design: </strong>Prospective observational study.</p><p><strong>Animal population: </strong>A total of 25 client owned dogs undergoing TPLO.</p><p><strong>Methods: </strong>Dogs undergoing TPLO with 21 mm osteotomy blades were enrolled. Intraoperatively, fluoroscopy was used to identify the intercondylar eminence (intended center of rotation), which was marked with a 0.035-inch Kirschner wire. The osteotomy site was dynamically adjusted to maintain a 21 mm radius from the center of rotation before proceeding with the osteotomy. Preoperative radiographic measurements (D1 and D2) were compared to intraoperative fluoroscopic measurements (R1 and R2) to assess reproducibility. Postoperative TPA was measured on routine radiographs.</p><p><strong>Results: </strong>A total of 30 TPLOs were performed. The median postoperative TPA based on fluoroscopic guidance was 3° (range: 0-4°). The median absolute difference between R1 and 21 mm was 0.5 mm (range: 0.0-3.0 mm), while the difference between R2 and 21 mm was 2.5 mm (range: 0.0-4.0 mm). D1 measurements demonstrated greater intraoperative reproducibility than D2.</p><p><strong>Conclusion: </strong>Fluoroscopy-assisted osteotomy placement resulted in precise postoperative TPA alignment with minimal deviation. Preoperative radiographic measurements were reproducible intraoperatively, with D1 showing higher accuracy than D2.</p><p><strong>Clinical significance: </strong>Intraoperative fluoroscopy improves the accuracy of osteotomy placement, leading to more precise postoperative TPA and potentially reducing surgical variability.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ex vivo comparison of jejunal transection angles and the effect on lumen diameter following end-to-end jejunojejunal anastomoses.","authors":"Christopher M Baldwin, Alexandra Gillen","doi":"10.1111/vsu.14294","DOIUrl":"https://doi.org/10.1111/vsu.14294","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate three different jejunal transection angles for end-to-end jejunojejunostomies, comparing construction time, lumen size, and suture number.</p><p><strong>Study design: </strong>Ex vivo cadaver study.</p><p><strong>Sample population: </strong>Eight euthanized horses each had three mid-jejunal specimens harvested.</p><p><strong>Methods: </strong>Jejunal segments were assigned to one of three groups (A30, A45, and A60) and transected at 30, 45, or 60°, respectively. Following transection, a standardized handsewn single-layer interrupted modified Lembert anastomosis was performed, and construction time and number of sutures placed were recorded. Anastomotic index (AI) was calculated. Statistical analysis was performed using a one-way ANOVA. Statistical significance was set at p < .05.</p><p><strong>Results: </strong>Transected jejunal lengths increased as the transection angle decreased (p < .001). Anastomoses construction time was not different between groups (p = .301). The number of sutures required to complete the anastomosis was higher (p = .026) for A30 compared to A60 but was not different between A60 and A45 or A45 and A30 (p > .333). Mean AI were 93.37, 114.29, and 135.07 for groups A60, A45, and A30 and the AI increased as the transection angle decreased (p < .001).</p><p><strong>Conclusion: </strong>A 60° transection angle reduced lumen size at the anastomosis but a 45 and 30° transection angle resulted in an increased lumen size at the anastomosis. The 45° angle did not increase the number of sutures required. The 30° angle significantly increased the number of sutures required.</p><p><strong>Clinical significance: </strong>A 45° angle of transection does not result in increased surgical time or number of sutures placed. Further investigation is required to determine the ideal angle of transection.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes and comparison of modified percutaneous cystolithotomy and traditional open cystotomy in 52 cats.","authors":"Alexis C Boone, Cassie N Lux, Katherine V Adair, Xiaocun Sun","doi":"10.1111/vsu.14288","DOIUrl":"https://doi.org/10.1111/vsu.14288","url":null,"abstract":"<p><strong>Objective: </strong>To compare short- and long-term clinical variables in cats undergoing a modified percutaneous cystolithotomy (PCCLm) or open cystotomy (OC) and to identify risk factors associated with complications and outcomes within the groups.</p><p><strong>Study design: </strong>Retrospective study.</p><p><strong>Animals: </strong>Fifty-two client-owned cats.</p><p><strong>Methods: </strong>Records were reviewed for cats that underwent PCCLm or OC between December 2010 and August 2023. Signalment, history, diagnostic findings, procedural and anesthetic details, hospitalization data, complications, urolith recurrence, and follow up were recorded. χ² or Fisher's exact tests and two-sample t-tests were used to evaluate effects of categorical and numerical clinical variables respectively on outcomes within PCCLm and OC groups and between PCCLm and OC groups.</p><p><strong>Results: </strong>A total of 54 procedures were performed, 19 PCCLm (36.5%) and 35 OC (65.5%). Hospitalization duration (p = .031) and incision length (p = .002) were greater in the OC group. Incisional infections were associated with hospitalization duration in the OC group (p = .048). Incomplete urolith removal was associated with increased surgical time (p = .039) when no additional procedures were performed in the OC group. For PCCLm, incomplete urolith removal was associated with lower urinary tract signs within 14 days postoperatively (p = .018), increased incision length (p = .029), anesthesia time (p = .017), and hospitalization duration (p = .027).</p><p><strong>Conclusion: </strong>Modified percutaneous cystolithotomy resulted in shorter incisions and hospitalization duration postoperatively in comparison with OC but no other clear advantages of PCCLm were identified.</p><p><strong>Clinical significance: </strong>The PCCLm procedure is an acceptable alternative to OC for urolith removal in cats.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a knotless barbed suture for canine total lung lobectomy: An ex vivo study.","authors":"Donghwi You, Hwi-Yool Kim","doi":"10.1111/vsu.14292","DOIUrl":"https://doi.org/10.1111/vsu.14292","url":null,"abstract":"<p><strong>Objective: </strong>To compare leakage pressure and ligation time of bronchial sealing using barbed sutures, stapling devices, or traditional sutures during total lung lobectomy in dogs.</p><p><strong>Study design: </strong>Experimental ex vivo study with randomized order of procedures.</p><p><strong>Sample population: </strong>A total of 30 lung lobes from five canine cadavers weighing 10-13 kg.</p><p><strong>Methods: </strong>The lobe samples were randomly allocated to the stapling device (ST), traditional suture ligation (TR), or barbed suture ligation (BA) group (n = 10 each). Bronchial ligation time was recorded for each procedure. Each bronchial stump was tested for air leakage for pressures up to 80 cmH₂O.</p><p><strong>Results: </strong>The median air leakage pressure was 45.0 cmH₂O (range: 30.0-80.0) for the ST, 47.5 cmH₂O (range: 36.0-80.0) for the TR, and 57.5 cmH₂O (range: 25.0-80.0) for the BA (p = .36). No group showed leakage at physiological airway pressures (< 20 cmH₂O). At pressures up to 80 cmH₂O, leakage was observed in nine of 10 bronchial stumps in the ST, eight of 10 in the TR, and six of 10 in the BA (p = .43). The mean bronchial ligation time was 2.4 ± 0.5 min for the ST, 14.1 ± 3.4 min for the TR and 10.7 ± 1.6 min for the BA (p < .01).</p><p><strong>Conclusion: </strong>Barbed sutures for bronchial closure provided comparable leakage pressure to stapling devices and traditional sutures and reduced suturing time compared to traditional sutures.</p><p><strong>Clinical significance: </strong>Barbed suture ligation might be a viable alternative for canine total lung lobectomy.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct arthroscopic approach to the distal pouch of the palmar/plantar recess of the metacarpophalangeal/metatarsophalangeal joint in horses.","authors":"Mathieu Foucaud, Liesbeth Haegeman, Dimitri Kadic, Tatiana Vinardell, Tom Mariën, Jeroen Declercq","doi":"10.1111/vsu.14290","DOIUrl":"https://doi.org/10.1111/vsu.14290","url":null,"abstract":"<p><strong>Objective: </strong>To describe a direct arthroscopic approach of the distal pouch of the palmar/plantar recess of the fetlock to facilitate fragment removal, highlighting its advantages over previously described arthroscopic methods for the fetlock. Additionally, to evaluate and present a retrospective case series.</p><p><strong>Study design: </strong>Ex vivo and retrospective clinical study.</p><p><strong>Sample population: </strong>A total of 25 fetlocks in 23 horses.</p><p><strong>Methods: </strong>A direct approach to the distal pouch of the palmar/plantar recess of the fetlock was developed on five cadaveric limbs. Arthroscopic anatomy and landmarks were examined. The approach was clinically used for fragment removal for 25 joints in 23 horses. An orthopedic examination was performed on all horses prior to surgery. Joints were evaluated for signs of joint disease related to the presence of fragments.</p><p><strong>Results: </strong>Consistent arthroscopic evaluation of the distal pouch of the palmar/plantar recess of the fetlock was achieved. All fragments were free floating and successfully removed. Signs of inflammation were present in all joints, with varying degrees of cartilage damage observed in 18 out of the 25 operated fetlocks.</p><p><strong>Conclusion: </strong>This approach is safe and enables the removal of fragments when present. Horses will benefit from fragment removal within the distal pouch of the palmar/plantar recess of the fetlock.</p><p><strong>Clinical significance: </strong>A new, direct arthroscopic approach to the distal pouch of the palmar/plantar recess of the fetlock is described. The approach facilitates fragment removal and provides new insights into joint health.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Femoral cortical thickness index in a population of dogs undergoing total hip replacement.","authors":"Charlotte B Pfund, Kirk L Wendelburg","doi":"10.1111/vsu.14275","DOIUrl":"https://doi.org/10.1111/vsu.14275","url":null,"abstract":"<p><strong>Objective: </strong>To establish a femoral cortical thickness index (CTI) for dogs undergoing total hip replacement (THR), determine the reproducibility of the established CTI measurements, and assess the efficacy of CTI as a preoperative variable in the femoral fracture/fissure occurrence in dogs undergoing THR.</p><p><strong>Study design: </strong>Retrospective study.</p><p><strong>Animals: </strong>A total of 224 dogs with THR.</p><p><strong>Methods: </strong>Medical records for dogs undergoing THR were reviewed retrospectively, analyzing only the first side in dogs with bilateral THR. Three measuring points were defined on preoperative mediolateral radiographs: immediately distal to the lesser trochanter, one-quarter-, and midway down the femur. The CTI was calculated from the mean cortical and femoral diaphyseal diameters at the established locations. A total of 10 dogs with varying CTI scores were selected for interobserver comparisons and pre-/ postoperative analyses. The relationship between CTI and perioperative fissure/fracture risk was then evaluated.</p><p><strong>Results: </strong>Interobserver and pre-/ postoperative measurement comparisons showed near-perfect correlation. Analysis of 224 dogs revealed a significant association between lower CTI and incidence of perioperative fractures (p < .0001). The mean CTI for all dogs was 0.285, while it was statistically lower at 0.246 for dogs that sustained fissures/fractures. No other statistically significant risk factors were identified.</p><p><strong>Conclusion: </strong>This study quantitatively assessed femoral cortical thickness in dogs undergoing THR. The findings confirmed that lower CTI is a repeatable and accurate predisposing factor for perioperative fissure/fracture risk in canine THR.</p><p><strong>Clinical significance: </strong>Factoring CTI into the clinical decision making may minimize fracture risk, especially in dogs with other possible risk factors such as abnormal BCS.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An in silico comparison of a novel CORA-based cranial closing wedge ostectomy methodology with three other techniques.","authors":"William H R Petchell, Anna R Bostock, Alexander J German, Andrew W Tomlinson","doi":"10.1111/vsu.14277","DOIUrl":"https://doi.org/10.1111/vsu.14277","url":null,"abstract":"<p><strong>Objective: </strong>To describe a CORA-based cranial closing wedge ostectomy methodology (CCWO_CORA) and to determine whether the CCWO_CORA achieves a more accurate and precise postoperative tibial plateau angle (TPA_POST) than three previously described methods.</p><p><strong>Study design: </strong>In silico study.</p><p><strong>Sample population: </strong>Thirteen client-owned dogs.</p><p><strong>Methods: </strong>Computed tomography (CT) scans of six Labrador retriever, six German shepherd, six Rottweiler, and six small-breed dog (<10 kg) tibiae, originally acquired for unrelated purposes, were used for in silico planning and execution of the CCWO_CORA and previously described procedures. The TPA_POST, tibial long axis shift, change in tibial length and wedge angle were recorded and a linear mixed-effects model was used to compare differences amongst techniques.</p><p><strong>Results: </strong>The median TPA_POST for the CCWO_CORA method was 5.00° (range: 5.00-5.00°) across a variety of tibial morphologies, whereas all other methods showed greater variability. Differences in TPA_POST were evident amongst methods (p < .001) and breeds (p < .001).</p><p><strong>Conclusions: </strong>In silico, CCWO_CORA methodology always achieved the target TPA_POST due to its intrinsic geometric principles. As such, CCWO_CORA surgeries achieved a more accurate TPA_POST than previously described CCWO techniques.</p><p><strong>Clinical significance: </strong>The CCWO_CORA provides clinicians with a cranial closing-wedge ostectomy methodology with entirely predictable TPA_POST.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-infrared fluorescence-guided minimally invasive surgery for iliosacral lymph node removal in 18 dogs (2023-2025).","authors":"Serena Monti, Fausto Brandao, Dario Drudi, Constantin V Ifteme, Bart Van Goethem, Paolo Sommaruga, Federico Massari","doi":"10.1111/vsu.14289","DOIUrl":"https://doi.org/10.1111/vsu.14289","url":null,"abstract":"<p><strong>Objective: </strong>To describe laparoscopic extirpation of iliosacral lymph nodes (ISLNs) in tumor-bearing dogs using near-infrared fluorescence (NIRF) guidance with indocyanine green (ICG), detailing the surgical technique and complications.</p><p><strong>Study design: </strong>Retrospective case series.</p><p><strong>Animal population: </strong>A total of 18 client-owned dogs.</p><p><strong>Methods: </strong>Medical records of dogs that underwent laparoscopic ISLN excision with NIRF-ICG guidance between July 2023 and January 2025 were reviewed. Collected data included tumor location and histotype, sentinel lymph node (SLN) identified on preoperative computed tomography (CT) lymphangiography, and number, size, and metastatic status of the excised ISLNs. Complications were classified as intra- or postoperative and graded using a modified Clavien-Dindo system.</p><p><strong>Results: </strong>A total of 25 ISLNs were laparoscopically excised: 18 medial iliac, three internal iliac, and four sacral. All patients were positioned in lateral recumbency, and resected ISLNs were ipsilateral to the primary tumor and laparoscopic ports. Median laparoscopic dissection time was 12 min. Histopathology confirmed metastasis in 12/25 ISLN. Median size of the excised ISLN was 5 × 6 mm. Two dogs (11.1%) required conversion to open surgery: one due to LN capsular disruption and dye spread, and one due to a lack of ICG uptake. No postoperative complications were documented.</p><p><strong>Conclusion: </strong>Laparoscopic ISLN removal under NIRF-ICG using a standardized lateral recumbency approach is feasible and enables access to unilateral ISLN. Intraoperative fluorescence facilitates precise localization of target nodes, especially those of normal size or mildly enlarged, minimizing dissection-related damage.</p><p><strong>Clinical relevance: </strong>This technique supports accurate staging of various neoplasms in dogs. Further studies are warranted to refine indications and patient selection.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Axial pattern flaps based on the dorsal and ventral perineal arteries: A cadaveric study in dogs and a case report.","authors":"Whitney Sia, Jennifer Wan, Daniel A Degner","doi":"10.1111/vsu.14283","DOIUrl":"https://doi.org/10.1111/vsu.14283","url":null,"abstract":"<p><strong>Objective: </strong>To describe the angiosomes of the dorsal and ventral perineal arteries in dogs and identify landmarks for axial pattern flaps based on these vessels. To describe the differences between male and female dogs regarding their respective angiosomes. To present a case report demonstrating the successful use of the dorsal perineal artery skin flap to reconstruct a perianal wound.</p><p><strong>Study design: </strong>Anatomic study.</p><p><strong>Animals: </strong>Eight canine cadavers: four males and four females. One clinical canine case.</p><p><strong>Methods: </strong>Nonselective barium sulfate angiography was performed via injection of the descending aorta. Skin excised from the perineum and thighs was evaluated via gross inspection and radiography to identify angiosomes. A single clinical case utilizing the dorsal perineal artery axial pattern flap was used to reconstruct a wound in a live dog.</p><p><strong>Results: </strong>A primary cutaneous branch of the ventral perineal artery was identified consistently in all cadavers with positive contrast radiography. The ventral perineal artery cutaneous angiosome was subjectively more robust than the dorsal perineal angiosome. A cutaneous branch of the dorsal perineal artery was observed radiographically in all specimens. The primary cutaneous angiosomes of both arteries extended at least two-thirds of the length of the caudal thigh. In the clinical case, a perineal wound was repaired successfully with a dorsal perineal artery flap.</p><p><strong>Conclusion: </strong>The ventral and dorsal perineal arteries possessed robust cutaneous angiosomes with apparently abundant vasculature and broad coverage on the caudal thigh, which were consistent in male and female cadavers.</p><p><strong>Clinical significance: </strong>The dorsal and ventral perineal arteries provide a rich blood supply to the skin of the caudal thigh. Axial pattern skin flaps created within these angiosomes may survive consistently.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saline-based modified del Nido cardioplegia versus multidose St. Thomas cardioplegia in canine mitral valve repair: A randomized controlled trial.","authors":"Kentaro Kurogochi, Arane Takahashi, Yasuyuki Nii, Ayaka Chen, Masako Nishiyama, Shimon Furusato, Hiroshi Sugiya, Masami Uechi","doi":"10.1111/vsu.14278","DOIUrl":"https://doi.org/10.1111/vsu.14278","url":null,"abstract":"<p><strong>Objective: </strong>To compare the utility of a saline-based modified del Nido (mDN) cardioplegia solution with a conventional institutional technique (multidose St. Thomas blood cardioplegia) for mitral valve repair (MVR) in dogs.</p><p><strong>Study design: </strong>Prospective, randomized, open-label trial.</p><p><strong>Animals: </strong>Forty client-owned dogs with myxomatous mitral valve disease (stage B2 and C) eligible for MVR were divided into control and modified mDN groups.</p><p><strong>Methods: </strong>Cardioplegia was induced in the control group using 50% blood containing St. Thomas solution every 10 min. In the mDN group, a cardioplegia solution containing 20% blood was administered once or when required. As the primary outcome, serum cardiac troponin I levels were compared 12 h postoperatively between the groups. The other clinical findings were evaluated as secondary outcomes.</p><p><strong>Results: </strong>Troponin levels 12 h after surgery were a median of 27.8 ng/mL (interquartile range, 15.1-43.2) in the control group and 19.4 ng/mL (15.2-33.6) in the mDN group (p = .478). The sinus rhythm recovery time following aortic cross-clamp removal was 362 s (103-995) in the control group and 60 s (44-605) in the mDN group (p = .027). The total amount of crystalloid cardioplegia solution required was 12.6 mL/kg (11.3-15.0) in the control group and 23.6 mL/kg (18.0-35.1) in the mDN group (p < .001).</p><p><strong>Conclusion: </strong>Cardiac troponin I levels did not show differences between the groups. The saline-based mDN cardioplegia facilitated earlier sinus rhythm recovery.</p><p><strong>Clinical significance: </strong>Saline-based mDN cardioplegia may be a viable alternative for canine MVR.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}