Veterinary Surgery最新文献

{"title":"Outcome following lag screw fixation of non-C3 carpal slab fractures in horses.","authors":"Jacqueline M Chevalier, Kara A Brown, Abigail Smith, Dean W Richardson, Kyla F Ortved","doi":"10.1111/vsu.70165","DOIUrl":"https://doi.org/10.1111/vsu.70165","url":null,"abstract":"<p><strong>Objective: </strong>To describe clinical features and short- and long-term outcomes of horses treated with lag screw fixation of slab fractures of the radial carpal (Cr), intermediate carpal (Ci), ulnar carpal (Cu), second (C2) or fourth (C4) carpal bones.</p><p><strong>Study design: </strong>Retrospective case study.</p><p><strong>Animals: </strong>Horses (n = 19) treated with lag screw fixation for slab fractures of Cr, Ci, Cu, C2 or C4.</p><p><strong>Methods: </strong>Medical records of patients with carpal slab fractures were reviewed, and those undergoing internal fixation of slab fractures involving Cr, Ci, Cu, C2, or C4 carpal bones from January 2008 to January 2026 were included. Long-term outcomes were obtained by a standardized questionnaire. Descriptive data are presented.</p><p><strong>Results: </strong>Predominant breeds included Thoroughbreds (7/19) and Warmbloods (7/19). A total of 10 of 19 fractures were caused by traumatic falls, including six during recovery from general anesthesia. Five of 19 surgeries were performed with arthroscopic guidance, and 14/19 surgeries were performed with computed tomography (CT) guidance. Survival beyond 1 year was 88%, with 53% returning to previous athletic function and 71% owner satisfaction.</p><p><strong>Conclusion: </strong>Prognosis for return to the previous level of work was good and comparable to that previously reported for internal fixation of C3 slab fractures.</p><p><strong>Clinical significance: </strong>Lag screw fixation provides good outcomes in survival, return to work, and owner satisfaction for slab fractures of Cr, Ci, Cu, C2, or C4.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149228820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel 3D-printed patient-specific limb-sparing radial endoprosthesis for treatment of primary osteosarcoma in a Great Dane.","authors":"Francesca Tavola, Jakub Kaczmarek, Bill Oxley, Karin Troedson","doi":"10.1111/vsu.70163","DOIUrl":"https://doi.org/10.1111/vsu.70163","url":null,"abstract":"<p><strong>Objective: </strong>To describe a novel titanium three-dimensional-printed patient-specific radial endoprosthesis (3D-PSE) for the successful treatment of a primary osteosarcoma in a 7-year-old female Great Dane.</p><p><strong>Study design: </strong>Case report.</p><p><strong>Methods: </strong>The dog presented with a 10-day history of swelling of the right distal radius. Computed tomography (CT) revealed an osteolytic lesion involving the distal metaphysis and diaphysis of the radius which was highly suspicious for an osteosarcoma (OSA). Thoracic CT showed no metastases. CT data was used to create a virtual 3D-model of the affected limb within computer-aided design software which was used for virtual osteotomy planning and the design of the 3D-PSE. During surgery 3D-printed patient-specific guides were used to execute osteotomies. The 3D-PSE comprised plate sections for attachment to the proximal radius and metacarpals 3, 4 and 5, and an integrated cage for bone graft to replace the radial defect. Histopathology demonstrated OSA, and postoperative adjuvant chemotherapy comprised five IV infusions of carboplatin every 3 weeks. The Liverpool Osteoarthritis in Dogs (LOAD) questionnaires were completed by the owner preoperatively and for each follow-up until the 6-month re-evaluation.</p><p><strong>Results: </strong>No complications occurred intra-/post- or perioperatively. LOAD scores preoperatively, and at 6, 12 and 24 weeks postoperatively were 19, 13, 11 and 10. Ten months after surgery thoracic radiographs revealed multiple pulmonary metastases, but the dog remained asymptomatic for a further 6 weeks when progressive dyspnea and lethargy prompted euthanasia. Lameness was absent at that time.</p><p><strong>Conclusion: </strong>The described novel 3D-PSE provided an effective function-preserving solution as part of a multimodal treatment of a giant breed dog with OSA of the distal radius.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transdiaphragmatic video-assisted lobectomy of caudal and accessory lung lobes: A canine cadaveric feasibility study.","authors":"Samuel Rico-Holgado, Sofia Garcia-Pertierra, Alvaro Martinez-Trapero, Maria Pera-Serrano, Jose L Fontalba-Navas, Ignacio Calvo","doi":"10.1111/vsu.70159","DOIUrl":"https://doi.org/10.1111/vsu.70159","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the feasibility and technical outcomes of a video-assisted transdiaphragmatic (VATD) approach to perform total lung lobectomy of the caudal and accessory pulmonary lobes in canine cadavers.</p><p><strong>Study design: </strong>Cadaveric study.</p><p><strong>Animals: </strong>A total of 12 canine cadavers.</p><p><strong>Methods: </strong>Cadavers were randomly assigned to left caudal, right caudal or accessory lung lobectomy (n = 4/group). A cranial midline celiotomy and transdiaphragmatic approach were performed with rigid videoendoscopic assistance under standardized procedural conditions. Lobectomies were completed using an endoscopic linear stapler. Recorded variables included achievement of complete pulmonary lobectomy, surgical times, incision length, and intraoperative technical events. Staple-line integrity was assessed using an air leak test. Descriptive statistics and logistic regression were used to evaluate results and associations with cadaver weight and body condition score (BCS).</p><p><strong>Results: </strong>Total lobectomy was achieved in 11/12 cadavers (91.7%), including all caudal lobes (100%) and three accessory lobes (75%). Mean total surgical time was 65.6 ± 26.8 min and incision length represented approximately one-third of abdominal midline length. Air leaks were identified in two accessory lung lobe lobectomies. No other intraoperative technical events were recorded. Two staple cartridges were required in 4/12 procedures (33.3%). Procedural success was not associated with cadaver weight or BCS.</p><p><strong>Conclusion: </strong>A VATD approach was feasible in canine cadavers and allowed total resection of caudal lung lobes, with slightly lower success for the accessory lung lobe.</p><p><strong>Clinical relevance: </strong>A VATD approach provided effective hilar exposure and acceptable procedural times in this cadaveric model. Further investigation in clinical patients is required to determine safety and clinical applicability and perioperative outcomes in dogs accurately.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical articular process joint versus ventral cervical stabilization in horses: A biomechanical study.","authors":"Machiel P Ysebaert, Ryan Foslien, Donovan M David, Andres F Bonilla, Ben C Gadomski, Jeremiah T Easley, Brad B Nelson","doi":"10.1111/vsu.70166","DOIUrl":"https://doi.org/10.1111/vsu.70166","url":null,"abstract":"<p><strong>Objective: </strong>To determine the biomechanical properties and modes of failure of a single level equine cervical spine immobilized with unilateral or bilateral articular process joint (APJ) stabilization, ventral cervical stabilization (VCS) and non-stabilized controls.</p><p><strong>Study design: </strong>Ex vivo experimental study.</p><p><strong>Sample population: </strong>A total of 24 equine cadaver cervical spines.</p><p><strong>Methods: </strong>Cervical spinal units (C4-C5) were randomly assigned to four groups (n = 6/group): unilateral APJ stabilization, bilateral APJ stabilization, VCS using pedicle screws and rod constructs, or non-stabilized. Non-destructive testing assessed kinematic range of motion (ROM), neutral zone, and stiffness in flexion-extension, axial rotation, and lateral bending. Specimens underwent four-point bending to failure (0.1 mm/s). Radiographs and visual inspection characterized failure mode. Groups were compared using one-way ANOVA or Kruskal-Wallis tests. Significance was p < .05.</p><p><strong>Results: </strong>Non-destructive testing showed unilateral and bilateral APJ constructs were stiffer in flexion-extension, axial rotation and lateral bending than non-stabilized (p < .05). In destructive testing, bilateral APJ stabilization was 2.5× stiffer than VCS, with similar failure moments. Construct stiffness was higher with bilateral APJ stabilization (27.89 ± 5.11 Nm/°) versus non-stabilized (6.92 ± 3.90 Nm/°, p = .0037), unilateral APJ (14.06 ± 2.94 Nm/°, p < .0001) and VCS (11.28 ± 3.01 Nm/°, p < .0001) groups. Failure typically occurred as cranial articular process fracture in both bilateral and unilateral APJ constructs.</p><p><strong>Conclusion: </strong>Bilateral APJ stabilization demonstrated greater stiffness than VCS with comparable failure moments.</p><p><strong>Clinical significance: </strong>Bilateral APJ stabilization, with its higher stiffness than VCS, may be an alternative strategy to achieve spinal fusion in horses while avoiding a ventral surgical approach. Future investigations and development of this technique in vivo are warranted before implementation in clinical cases.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of intra-articular injectate volume on joint surface coverage and leakage following canine elbow arthroscopy: A cadaveric study.","authors":"Erin Smith, Sarah Stark, Shelby Boynton, Wanda Gordon-Evans","doi":"10.1111/vsu.70141","DOIUrl":"10.1111/vsu.70141","url":null,"abstract":"<p><strong>Objective: </strong>To determine whether reduced intra-articular (IA) injection volumes provide complete synovial surface coverage while minimizing leakage following canine elbow arthroscopy.</p><p><strong>Study design: </strong>Randomized cadaveric study.</p><p><strong>Animals: </strong>Forty elbow joints from 20 canine cadavers weighing >15 kg.</p><p><strong>Methods: </strong>Standard medial elbow arthroscopy was performed with portals placed under arthroscopic guidance. The egress portal was created along the caudal margin of the medial epicondylar ridge, directed toward the anconeal process. A third, craniomedial instrument portal was created approximately 1 cm cranial to the camera portal. Following arthroscopy, India ink-volume-matched to whole, half, or quarter of a 0.5 mg/kg ropivacaine dose (0.75% concentration)-was injected via the egress portal. Each joint underwent 10 passive flexion-extension cycles before dissection. A masked investigator (ES) qualitatively assessed synovial surface coverage (100%, 75%-99%, 50%-74%, 25%-49%, 0%-24%) and leakage severity (mild, moderate, severe). Portal placement attempts, cadaver age, and bodyweight were recorded.</p><p><strong>Results: </strong>Mean cadaver age was 9.3 years (range: 1-16 years), and mean weight was 29.9 kg (range: 17.9-43.6 kg). Complete (100%) synovial surface coverage was observed in all 40 elbows, including those receiving quarter-dose injections. Leakage occurred in every dose group, with a similar distribution of mild, moderate, and severe categories. Portal placement was successful on the first attempt in 32 elbows (80%) and the second attempt in eight elbows (20%).</p><p><strong>Conclusion: </strong>Reduced IA injection volumes achieved complete synovial surface coverage but did not reduce leakage severity.</p><p><strong>Clinical significance: </strong>Reduced intra-articular injection volumes were sufficient to achieve complete synovial surface coverage in this model, suggesting potential flexibility in clinical dosing strategies. Nonetheless, extravasation occurred at all tested volumes, reinforcing that some leakage should be expected in practice.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":"1237-1245"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148685950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of one-lung ventilation on sentinel lymph node mapping in dog lungs.","authors":"Sarah J Marvel, Nontalie Kaschark, Pedro Boscan, Eric Monnet","doi":"10.1111/vsu.70145","DOIUrl":"10.1111/vsu.70145","url":null,"abstract":"<p><strong>Objective: </strong>To determine the sentinel lymph node (SLN) for the caudal lung lobe using indocyanine green (ICG) and near infra-red fluorescence (NIRF) in normal dogs. The secondary objective was to determine the effect of one lung ventilation (OLV) on time to SLN detection.</p><p><strong>Study design: </strong>Prospective, randomized experimental study.</p><p><strong>Animals: </strong>Purpose-bred Beagles (n = 21).</p><p><strong>Methods: </strong>Dogs were randomized to undergo OLV or normal ventilation (NV) and to undergo right or left caudal lung injections with ICG through lateral intercostal thoracoscopy. The draining lymph nodes (DLNs) were visualized at 10 min intervals.</p><p><strong>Results: </strong>A fluorescent lymph node (FLN) was detected in 19/21 dogs (90%) and was the right or left tracheobronchial lymph node (LN) in 79% of dogs. Six dogs had multiple FLNs detected simultaneously. In 4/19 dogs (21%) the first FLN(s) was the central tracheobronchial LN, sternal LN, cranial mediastinal LN or a combination of these LNs. The median time to fluorescence in the first FLN was 30 min (range: 10-50 min) for the OLV group and 10 min (range: 10-20 min) for the NV group (p = .0012).</p><p><strong>Conclusion: </strong>The SLN or DLN for the caudal lung in normal dogs was variable, but often included the tracheobronchial LN. One lung ventilation slowed the detection of ICG in the lymphatics.</p><p><strong>Clinical significance: </strong>Biopsy of tracheobronchial LNs for caudal lung tumors without SLN mapping may provide inaccurate staging information in some dogs. During NIRF-guided SLN mapping, delaying OLV induction may improve SLN identification.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":"1286-1293"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed tomography versus magnetic resonance imaging for the perioperative management of acute thoracolumbar intervertebral disc extrusion in non-ambulatory chondrodystrophic dogs.","authors":"Daniel Low, Andrea Markovic","doi":"10.1111/vsu.70135","DOIUrl":"10.1111/vsu.70135","url":null,"abstract":"<p><strong>Objective: </strong>To determine whether perioperative management guided by conditional computed tomography-myelography (C-CTM) is non-inferior to magnetic resonance imaging (MRI) regarding functional outcome for acute thoracolumbar intervertebral disc extrusion (IVDE) in non-ambulatory chondrodystrophic dogs.</p><p><strong>Study design: </strong>Quasi-randomized natural experiment utilizing unscheduled MRI downtime as an exogenous instrument.</p><p><strong>Sample population: </strong>A total of 560 client-owned dogs (MRI, 518 dogs; C-CTM, 42 dogs).</p><p><strong>Methods: </strong>A retrospective cohort study was conducted. The primary outcome was recovery of ambulation, analyzed with intention-to-treat (ITT) and per-protocol (PP) principles with a prespecified non-inferiority margin of -12%. Secondary outcomes included safety events (postoperative neurologic deterioration, progressive myelomalacia, major complications) and time-adjusted treatment costs.</p><p><strong>Results: </strong>C-CTM was non-inferior to MRI for recovery of ambulation in both ITT (risk difference + 6.5%, 95% CI: -2.7%-15.7%, one-sided p < .001) and PP analyses (risk difference + 2.5%, 95% CI: -7.3%-12.2%, one-sided p < .001). There was no difference in rates of postoperative neurologic deterioration, progressive myelomalacia, or major complications. Total treatment costs and imaging costs were significantly lower for C-CTM (p < .01). There was no difference in non-imaging costs between groups.</p><p><strong>Conclusion: </strong>In non-ambulatory chondrodystrophic dogs with acute thoracolumbar IVDE, C-CTM is non-inferior to MRI for recovery of ambulation with a similar safety profile, at significantly lower cost.</p><p><strong>Clinical significance: </strong>In dogs with a high pretest probability of acute thoracolumbar IVDE, routine use of MRI may not be justified given the comparable clinical outcomes and lower treatment costs achieved with C-CTM.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":"1198-1211"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation exposure to equine surgeons during simulated digital radiography and fluoroscopy-guided fracture fixation of the distal limb.","authors":"Julia L Gaida, Susanne M Stieger-Vanegas, Christoph J Lischer, Katja F Duesterdieck-Zellmer, Michael J Huber, J Lacy Kamm","doi":"10.1111/vsu.70126","DOIUrl":"10.1111/vsu.70126","url":null,"abstract":"<p><strong>Objective: </strong>Despite known occupational radiation risks, data on exposure during digital radiography (DR) or fluoroscopy-guided equine fracture repair are lacking. This study quantified radiation doses to a model surgeon's hand, lenses, thyroid, and gonads, and assessed protective effects of radiation-reducing surgical gloves and attenuating ointment.</p><p><strong>Study design: </strong>Comparative, controlled, simulation-based study.</p><p><strong>Animal/sample population: </strong>Anthropomorphic model.</p><p><strong>Methods: </strong>Distal limb fracture fixation was simulated using a model with dosimeters at the region of the lenses, thyroid, gonads, drill-holding hand, and under a lead apron (fetal dose). Radiation was measured over 10 DR or 10 single-image fluoroscopy exposures, then repeated using radiation-reducing surgical gloves or ointment.</p><p><strong>Results: </strong>All radiation doses were below occupational limits. Dosimeters placed at the level of the gonads (outside the gown) received the highest mean dose (DR: 6.87 ± 0.40 μSv; fluoroscopy: 0.98 ± 0.28 μSv), followed by thyroid (outside the gown) (DR: 2.60 ± 0.52 μSv; fluoroscopy: 0.48 ± 0.08 μSv), hand (DR: 2.02 ± 0.54 μSv; fluoroscopy: 0.32 ± 0.06 μSv) and lenses (DR: 1.25 ± 0.28 μSv; fluoroscopy: 0.23 ± 0.07 μSv). The lowest exposure was measured underneath the gown (fetal dose) (DR: 0.01 ± 0.01 μSv; fluoroscopy: 0.01 ± 0.01 μSv). DR exposure exceeded fluoroscopy at all sites (p < .001). Radiation-reducing surgical gloves significantly lowered hand dose (p < .001), whereas ointment had no effect (p = .54). Off-beam hand exposure from 10 images was approximately one-millionth of the annual dose limit.</p><p><strong>Conclusion: </strong>Image-guided equine distal limb fracture fixation results in minimal hand radiation exposure, relative to other regions of the body, with DR producing higher doses than single-image fluoroscopy. Radiation-reducing surgical gloves significantly lower hand exposure during DR procedures.</p><p><strong>Clinical significance: </strong>Radiation-reducing surgical gloves offer additional protection and are recommended during image-guided surgery. Whenever feasible, pulsed fluoroscopy should be preferred over DR.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":"1212-1222"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148333196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical closure of labial and alveolar cleft defects with a modified Millard technique: A prospective study of ten dogs.","authors":"Pierre Maitre, Mathieu Jourdain, Pauline Brignon, Justine Loin, Pierre Corre, Olivier Gauthier","doi":"10.1111/vsu.70120","DOIUrl":"10.1111/vsu.70120","url":null,"abstract":"<p><strong>Objective: </strong>To provide a step-by-step description of canine lip/alveolar cleft repair, describe intra- and postoperative complications, and report mid-term clinical, functional and cosmetic outcomes.</p><p><strong>Study design: </strong>Prospective study.</p><p><strong>Animals: </strong>A total of 10 client-owned puppies with unilateral or bilateral lip/alveolar clefts.</p><p><strong>Methods: </strong>Detailed clinical and historical data were recorded. The lip/alveolar clefts were repaired using a surgical technique adapted from human medicine including: (1) alveolar cleft and labial vestibulum repair, (2) cheilorhinoplasty and (3) palatal cleft repair when indicated. Intra- and postoperative complications, as well as clinical, functional and cosmetic outcomes, were recorded at 7 and 14 days and at a minimum of 3 months postoperatively. Cosmetic outcomes were evaluated using postoperative CT measurements.</p><p><strong>Results: </strong>A total of 10 puppies (4 males, 6 females) were included. Of these, six presented with unilateral lip/alveolar clefts (2 right-sided and 4 left-sided) and four presented with bilateral clefts. A total of 14 lip/alveolar clefts were repaired. Four dogs had a complete secondary palate cleft. No intraoperative surgical complications were reported. Three cases of minor dehiscence of the cheilorhinoplasty suture line were observed, all healed by second intention within 14 days postoperatively. One case of oronasal communication on the hard palate was successfully treated with minor revision surgery. Successful clinical and functional outcomes were reported for all dogs at the 3-month postoperative evaluation. Overall cosmetic outcomes were rated as good to excellent.</p><p><strong>Conclusion: </strong>The described step-by-step surgical technique resulted in good to excellent clinical, functional, and cosmetic outcomes.</p><p><strong>Impact: </strong>This technique offers a new surgical treatment with a low complication rate.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":"1261-1274"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148621514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinically relevant intra-articular corticosteroid doses impair equine osteoclast function in vitro.","authors":"Gwladys Malek, Louis Kamus, Hélène Richard, Guy Beauchamp, Sheila Laverty","doi":"10.1111/vsu.70132","DOIUrl":"10.1111/vsu.70132","url":null,"abstract":"<p><strong>Objective: </strong>To assess the effects of clinically relevant doses of commonly employed intra-articular corticosteroids-specifically, triamcinolone acetonide (TCA), methylprednisolone acetate (MPA), and combination of betamethasone acetate and betamethasone sodium phosphate (BM)-on equine osteoclasts.</p><p><strong>Study design: </strong>In vitro controlled laboratory study.</p><p><strong>Sample population: </strong>Three donor mares (13-19 years).</p><p><strong>Methods: </strong>Following differentiation from bone marrow aspirates, osteoclasts were cultured alone (pure osteoclast cultures; n = 18 wells per group) or on equine bone slices (osteoclast-bone cultures; n = 6 wells per group) and treated with TCA (36 μg/mL), MPA (48 μg/mL), or BM (4 μg/mL). Untreated wells were controls. Outcome parameters included number of osteoclasts, bone resorption area and media biomarker concentrations, specifically tartrate-resistant acid phosphatase isoform-5b (TRACP-5b) and C-terminal telopeptide of type I collagen (CTX-I), measured using enzyme-linked immunosorbent assay (ELISA).</p><p><strong>Results: </strong>In pure osteoclast cultures (n = 16 wells in control and BM groups; n = 17 wells in TCA and MPA groups), mature osteoclast numbers were lower following corticosteroid addition compared with controls (MPA, p < .001; TCA, p = .009; BM, p = .002), and lower in the MPA group than the TCA group (p = .015). There was no difference in TRACP-5b between groups. In osteoclast-bone cultures (n = 5 in control group; n = 6 wells in TCA, MPA and BM groups), CTX-I decreased with MPA treatment compared with controls (p = .001), TCA (p = .006), and BM (p = .007) groups. TRACP-5b decreased with TCA compared with controls (p = .001). No differences in bone resorption area were measured.</p><p><strong>Conclusion: </strong>Clinically relevant doses of commonly employed intra-articular corticosteroids-TCA, MPA, and BM-impacted equine osteoclast activity in vitro.</p><p><strong>Clinical significance: </strong>Understanding that intra-articular corticosteroids may influence osteoclast activity, potentially affecting subchondral bone remodeling and repair, is important for guiding judicious use in equine joint management.</p>","PeriodicalId":23667,"journal":{"name":"Veterinary Surgery","volume":" ","pages":"1223-1236"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148607916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}