Voprosy pitaniia最新文献

{"title":"[State of the hepatobiliary system on the data of ultrasonic examination in children and adolescents with overweight and obesity].","authors":"I E Shtina, Yu A Ivashova, N I Mamykina, O Yu Ustinova","doi":"10.33029/0042-8833-2023-92-2-60-70","DOIUrl":"10.33029/0042-8833-2023-92-2-60-70","url":null,"abstract":"<p><p>Currently, a stable increase in the incidence of overweight and obesity is noted, this fact leads to an elevation in comorbidity with them. The relevance of the study is due to the involvement of the hepatobiliary system in the development of metabolic dysfunction and the formation of non-alcoholic fatty liver disease in the future. <b>The aim</b> of the research was to study the effect of overweight and obesity in children and adolescents on the state of the hepatobiliary system on the basis of ultrasound examination. <b>Material and methods</b>. A single-center retrospective comparative study was conducted. The main group consisted of 112 children and adolescents with Z-score body mass index (BMI) above +1SD, the comparison group consisted of 264 persons with a BMI from -2 to +1SD aged 5-17 years. An analysis of the results of anthropometric, including the assessment of BMI, ultrasound and biochemical studies was carried out. <b>Results</b>. The Z-score of BMI corresponding to overweight was recorded in 54 (13.8%) examined persons, and obesity - in 58 (14.8%) patients. In children of the main group, an increase in the size of the liver was recorded 3.6 fold more often, diffuse changes in the liver were revealed 32.4 fold more often, an increase in the volume of the gallbladder - 2.1 fold, signs of excessive aerocolia - 3.3 fold more often (p<0.001). In children with overweight and obesity, the level of triglycerides (p=0.003), low-density lipoprotein cholesterol (p=0.035), glucose (p=0.012), C-reactive protein (p=0.011), malon dyalldehyde (p=0.012), the activity of alaninaminotransferase (p<0.001) and alkaline phosphatase (p=0.001) were statistically significant, with a significantly lower level of high-density lipoprotein cholesterol (p<0.001). Statistically significant logistic models of the probability of an increase in the linear dimensions of the liver, diffuse changes, an increase in the volume of the gallbladder, the presence of excessive aerocolia signs from the Z-score BMI value were obtained. The Nigelkirk determination coefficient was 0.34, 0.17, 0.11 and 0.10 c.u. respectively. <b>Conclusion</b>. The contribution of overweight and obesity to the increase in the linear dimensions of the liver and the volume of the gallbladder, the formation of diffuse changes and excessive aerocolia according to the ultrasound examination was 10-34%.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 2","pages":"60-70"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10058989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Contemporary approaches to the assessment of energy intake and energy expenditure in athletes].","authors":"E A Bushmanova, A Yu Lyudinina","doi":"10.33029/0042-8833-2023-92-5-16-27","DOIUrl":"10.33029/0042-8833-2023-92-5-16-27","url":null,"abstract":"<p><p>Assessment and interpreting of the energy expenditure (EE) in highly skilled athletes are important components of an effective training and performance prediction. Each component of EE (resting energy expenditure, thermic effect of food, and physical activity energy expenditure) is closely related to dietary patterns, the intensity and duration of physical activity, as well as a number of other factors that affect the functional state of athletes. Despite the importance of EE in the training process, coaches and athletes often do not take EE into account, which reduces the objectivity of assessing athletes' functional state. <b>The purpose</b> of this research was to summarize the recent information on the structure of EE and energy consumption in athletes. <b>Material and methods</b>. The search and analysis of publications was carried out using the PubMed, MEDLINE, Scopus, Web of Science, eLIBRARY databases, mainly for the last 10 years, using the search keywords: rest energy expenditure, thermic effect of food, physical activity energy expenditure, energy intake, total energy expenditure, athletes. <b>Results</b>. This overview includes information on the components of total energy expenditure, such as rest energy expenditure, thermic effect of food and physical activity energy expenditure, as well as generalized information on the factors affecting the variability of their values and methods for assessing one or another type of energy expenditure. International nutritional recommendations regarding the level of physical activity of athletes are systematized, as well as the advantages and disadvantages of methods for studying energy consumption and total energy expenditure are presented. <b>Conclusion</b>. Combined study of energy intake and energy expenditure will help athletes avoid the negative impact of energy deficiency on performance, and the correct construction of the training process with the maintenance of adequate energy consumption will have a positive impact on the performance and recovery processes after intensive physical exertion.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 5","pages":"16-27"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Associations between dietary factors and periodontal status among 12-year-old children in Arkhangelsk region].","authors":"M A Gorbatova,&nbsp;P A Pochinkova,&nbsp;A M Grjibovski","doi":"10.33029/0042-8833-2023-92-1-63-73","DOIUrl":"https://doi.org/10.33029/0042-8833-2023-92-1-63-73","url":null,"abstract":"<p><p>Nutrition is an important determinant of human health particularly in childhood since dietary habits and metabolic patterns are formed during this period of life. Certain nutritional factors may increase the risk for periodontal diseases (PD). Considering the associations between periodontal health and cardiovascular diseases, studies on the associations between nutritional factors and periodontal diseases are of particular importance. <b>The aim</b> of the research was to study the patterns of consumption of certain foods associated with oral health according to the World Health Organization (WHO) and to assess the associations between these factors and PD among 12-year-old children in Arkhangelsk region of Russian Federation. <b>Material and methods</b>. In total, 1162 12-year-old children from 7 urban and 5 rural settings of Arkhangelsk region participated in a cross-sectional study. Dental status was assessed as recommended by the WHO (2013). To assess the periodontal status of a child, a communal periodontal index was used, which included 2 indicators: the presence of bleeding during probing and calculus. A WHOdeveloped questionnaire was used to study nutritional patterns related to oral health. Associations between socio-demographic factors and patterns of consumption of selected food items were assessed using Person's chi-squared tests. Associations between periodontal disease, bleeding, calculus, and nutritional factors were studied by multivariable logistic regression. Relationships between the number of affected sextans and frequency of consumption of selected foods was assessed using multivariable Poisson regression models. <b>Results</b>. More frequent consumption of sweet carbonated drinks was associated with male sex, rural living, and low educational levels of both parents. Higher levels of education for both mother and father were associated with more frequent consumption of fresh fruit (p=0.011 and p=0.002). The prevalence of dental calculus and the number of affected sextants with calculus were inversely related to the frequency of fresh fruit consumption (p=0.012 and p<0.001, respectively). The number of sextants with calculus and PD in general were inversely associated with the frequency of consumption of homemade jam and honey (p=0.036 and p=0.043, respectively). <b>Conclusion</b>. The frequency of consumption of the foods affecting oral health was significantly associated with socio-demographic factors in Arkhangelsk region. Daily consumption of fresh fruits was associated with lower prevalence of calculus. The lowest number of affected sextants with bleeding, calculus, and PD was revealed when homemade jams or honey was consumed at least once a week, but less than every day.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 1","pages":"63-73"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9136737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Features of the metabolism of polyunsaturated fatty acids in type 2 diabetes mellitus].","authors":"Kh Kh Sharafetdinov,&nbsp;R I Alekseeva,&nbsp;O A Plotnikova,&nbsp;V V Pilipenko,&nbsp;E Yu Sorokina","doi":"10.33029/0042-8833-2023-92-3-15-24","DOIUrl":"https://doi.org/10.33029/0042-8833-2023-92-3-15-24","url":null,"abstract":"<p><p>Type 2 diabetes mellitus (T2DM) is a widespread disease with a high risk of cardiovascular complications, disability and mortality. The progression of T2DM is closely related to lipid metabolism disorders, caused both by insufficient intake of polyunsaturated fatty acids (PUFAs), and by a violation of their endogenous metabolism. Desaturase enzymes, FADS1/2, are involved in the regulation of PUFA metabolism. Violation of the functioning of FADS1/2 and their genes leads to a change in the biosynthesis of PUFAs and the fatty acid composition of cell membranes. <b>The purpose</b> of this research was to summarize the data of modern literature on the metabolism of PUFAs and the effect of FADS genetic variants on the fatty acid composition of cell membranes in T2DM. <b>Material and methods</b>. The search and analysis of publications was carried out using the PubMed, MEDLINE, Web of Science databases, mainly for the last 10 years, using the search keywords: polyunsaturated fatty acids, fatty acid desaturases, desaturase genes, type 2 diabetes mellitus. <b>Results</b>. In the pathogenesis of T2DM and its complications, many factors play a role, including impaired PUFA metabolism. A large evidence base has been accumulated on the effect of PUFAs on cardiometabolic risk factors in T2DM. The effect of desaturase activity on the fatty acid composition of cells was identified as the most important link in the metabolism of PUFAs. Focusing on the modulation of desaturase activity and studying the polymorphism of fatty acid desaturase genes may be a useful therapeutic option in the treatment of patients with T2DM and its complications. <b>Conclusion</b>. A promising direction of scientific research in the treatment and prevention of T2DM and its complications is the study of genetic mechanisms associated with the metabolism of PUFAs and their metabolites.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 3","pages":"15-24"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10171453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotic microorganisms Lactobacillus paracasei paracasei and Bifidobacterium animalis lactis do not affect the severity of metabolic disorders and the development of obesity in Wistar rats fed a high-calorie diet","authors":"I.V. Aksenov","doi":"10.33029/0042-8833-2023-92-5s-003","DOIUrl":"https://doi.org/10.33029/0042-8833-2023-92-5s-003","url":null,"abstract":"","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The influence of environmental factors on the prevalence of «thrifty genotypes» as predictors of metabolic disorders].","authors":"A I Kozlov, O I Parfenteva, E V Gasanov","doi":"10.33029/0042-8833-2023-92-6-18-27","DOIUrl":"10.33029/0042-8833-2023-92-6-18-27","url":null,"abstract":"<p><p>\"Thrifty genotypes\" are the risk factors for obesity and lipid and energy metabolism disorders. Hence, it is important to assess the contribution of environmental factors that influenced the thrifty genotypes' population distribution. <b>Aim</b> of the study - systematization and critical analysis of published data on population variability, relationship with climatic and environmental characteristics, association with traditional types of lifestyles, and nutrition for the «thrifty genotypes» of APOE, UCP1, UCP3, and FTO genes. <b>Material and methods</b>. The selection of publications from the last 20-25 years presented in the PubMed database (https://pubmed.ncbi.nlm.nih.gov) was carried out by the keywords of the generalizing rank (thrifty genotype, thrifty phenotype, drifty genotype), then narrowed down to the APOE, UCP, FTO. The final set includes publications that consider the association of genotypes with the ecological conditions of the population. <b>Results</b>. Our analysis of publications has confirmed the ethnic and geographical variability in the allele distribution of APOE, UCP1, UCP3, and FTO genes. However, the nature of this variability hasn't been studied sufficiently; the contribution of individual factors of the natural and anthropogenic environment remains unclear. The information on the geographical distribution of the APOE gene alleles is quite complete, while the data on the «thrifty genotypes» of UCP and FTO require further study. <b>Conclusion</b>. The frequency of the UCP1 and UCP3 alleles associated with effective non-contractile thermogenesis is increased in populations adapted to low temperatures. However, the population-geographical pattern of the UCP thrifty genotypes' variability as a determinant of increased fat deposition has been studied insufficiently. The carriage of FTO mutant variants increases the adaptability of groups with a traditional lifestyle and diet but is maladaptive in an urbanized environment. The influence of natural and ecological conditions on the formation of the FTO allele geographical distribution requires more attention. The results obtained allow us to propose the included groups' ranking according to the past environmental management and nutrition will facilitate the search for ecological factors that influenced the geographical distribution of genotypes (and, accordingly, populations with different levels of risk of metabolic disorders).</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 6","pages":"18-27"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mycotoxins in spices consumed in Russia].","authors":"Z A Chalyy, M G Kiseleva, I B Sedova, V A Tutelyan","doi":"10.33029/0042-8833-2023-92-2-26-34","DOIUrl":"10.33029/0042-8833-2023-92-2-26-34","url":null,"abstract":"<p><p>Spices and herbs have been used since ancient times as flavor and aroma enhancers, colorants, preservatives and traditional medicines. As many other plant products, they can be exposed to contaminants, ones of which are mycotoxins, secondary metabolites of fungi. Such contamination can occur during harvesting, processing and storage, distribution, retailing and consumer use. Although they are used and consumed in small quantities, but added to a wide variety of products, especially ready-to-eat products. So the assessment of their contamination with mycotoxins is very important. <b>The aim</b> of the study was to investigate the contamination of spices and herbs with mycotoxins of fungi of the genera Aspergillus, Penicillium, Fusarium and Alternaria, as well as to assess the mycotoxins intake per person when consuming these food groups. <b>Material and methods</b>. Concentration of mycotoxins in 155 samples of spices and herbs was determined by ultra high-performance liquid chromatography coupled to tandem mass-spectrometric detection (UHPLC-MS/MS). The list of mycotoxins included deoxynivalenol, aflatoxins, ochratoxin A, zearalenone, T-2 toxin, fumonisins, sterigmatocistin, HT-2 toxin, diacetoxyscirpenol, enniatins, beauvericin, neosolaniol, citreoviridin, mycophenolic acid, citrinin, tentoxin, altenuene, alternariol and its monomethyl ether. <b>Results</b>. Among the regulated in plant products mycotoxins in the studied samples there were found aflatoxins (B1 - in 19% of samples, from 0.4 to 48.2 μg/kg, B2 - 8%, from < limit of quantitation (LOQ) to 3.2 μg/kg, G1 - 2%, 0.75-21 μg/kg, G2 - 5%, 0.5- 12.5 μg/kg), ochratoxin A (15% samples, 0.8-14 μg/kg), fumonisin B1 (8%, 16.1-722.6 μg/kg), and fumonisin B2 (14%, < LOQ - 79.6 μg/kg). T-2 toxin and deoxynivalenol were found in 10% of samples (< LOQ - 6.5 μg/kg and < LOQ - 65.5 μg/kg respectively), zearalenone - in 4 samples (1.7-106.2 μg/kg), HT-2 toxin - in 8 samples (5.4-19.8 μg/kg). Among little-studied (emergent) mycotoxins in the spices and herbs samples there were found tentoxin (in 36% of samples, in an amount from 0.7 to 10.9 μg/kg), altenuene (in 8%, 14.5-161.5 μg/kg). 10% of the samples were contaminated with alternariol and its methyl ether (from less than LOQ to 12.8 and < LOQ to 55.7 μg/kg, respectively), 4% - with sterigmatocystin (0.4-7.8 μg/kg), 5% - mycophenolic acid (13.1-297 μg/kg), 2% of the samples were contaminated with citrinin and enniatin B (< LOQ - 27.7 and 0.1-1 μg/kg), in 9 samples (6%) beauvericin was detected (< LOQ - 1.7 μg/kg). Over 60% of samples were contaminated with more than one mycotoxin. The content of aflatoxin B1 exceeded the maximum permissible level set in the EU (5 μg/kg) in nine samples. <b>Conclusion</b>. To the best of our knowledge, the present study is the first in the Russian Federation to report results indicating to the contamination of spices and herbs with mycotoxins. High occurrence of aflatoxins, tentoxin, ochratoxin A and fumonisin B2 h","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 2","pages":"26-34"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9684237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Bioactive compounds anthocyanins as a factor in the nutritional recovery of the body's adaptive potential after intense physical activity in the experiment: assessment of immunological and hematological indicators of adaptation].","authors":"E N Trushina,&nbsp;O K Mustafina,&nbsp;I V Aksenov,&nbsp;A G Krasutsky,&nbsp;D B Nikityuk,&nbsp;V A Tutelyan","doi":"10.33029/0042-8833-2023-92-1-6-15","DOIUrl":"https://doi.org/10.33029/0042-8833-2023-92-1-6-15","url":null,"abstract":"<p><p>Restoring the adaptive potential of an athlete is of paramount importance not only for the implementation of his training and competitive activities, but also for maintaining health. One of the leading place in complex recovery programs in sports is given to full-fledged optimal nutrition, which provides for meeting the body's requirements not only in energy, macro- and micronutrients, but also in minor bioactive compounds. The use of anthocyanin-containing products is a promising strategy for the normalization of metabolic and immune disorders that develop as a result of intense physical and neuro-emotional stress not only in athletes, but also in other groups of people exposed to these factors, including military personnel undergoing training in conditions close to combat. This determines the relevance of this study. <b>The aim</b> of the research was to study the effect of an anthocyanin-enriched diet on hematological profile and cellular immunity in rats after intense physical activity. <b>Material and methods</b>. The experiment was carried out for 4 weeks on 4 groups of male Wistar rats with an initial body weight of ~300 g. The motor activity of the animals of the 1st (control) and 2nd groups was limited by the standard keeping animals in the vivarium, while physically active rats of the 3rd and 4th groups received additional physical activity - training on a treadmill. Before the end of the experiment, the animals of 3rd and 4th groups were given debilitating physical activity on a treadmill (until the rats refused to continue the exercise). Rats of all 4 groups received a standard semi-synthetic diet, water ad libitum. Animals in 2nd and 4th groups were additionally fed blueberry and blackcurrant extract (30% anthocyanins) as part of the diet at a daily dose of 15 mg anthocyanins/kg body weight. Hematological parameters were determined on a Coulter ACT TM 5 diff OV hematological analyzer. Expression of CD45R, CD3, CD4, CD8a, CD161 receptors on rat peripheral blood lymphocytes was determined by direct immunofluorescent staining of whole blood cells using a panel of monoclonal antibodies conjugated with fluorescent dyes: APC, FITC, PE. The measurements were carried out on an FC-500 flow cytometer. <b>Results</b>. Intense physical activity in rats of the 3rd group did not lead to a significant change in erythrocyte parameters compared with the control group. Enrichment of the diet with blueberry and black currant extract (the 2nd and the 4th groups) provided a significant (p<0.05) increase in blood content of hemoglobin (Hb) (150.7±0.9 and 154.4±2.0 vs 145.4±0.9 g/l in control), hematocrit (44.95±0.21 and 46.18±0.64 vs 43.78±0.32%) and the average content of Hb in erythrocytes (18.00±0.20 and 18.03±0.24 vs 17.35±0.24 pg). The absolute content of leukocytes and other cellular elements of the leukocyte formula, as well as leukocyte indices in rats of the experimental groups didn't significantly differ from those of the control rats, whi","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 1","pages":"6-15"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9136736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Nutrition and adipose tissue distribution in low cardiovascular risk individuals, depending on the central obesity].","authors":"S O Eliashevich,&nbsp;M V Khudyakov,&nbsp;O V Senko,&nbsp;A V Kuznetsova,&nbsp;O T Kim,&nbsp;D D Nunes Araukho,&nbsp;O M Drapkina","doi":"10.33029/0042-8833-2023-92-1-74-84","DOIUrl":"https://doi.org/10.33029/0042-8833-2023-92-1-74-84","url":null,"abstract":"<p><p>The low cardiovascular risk group according to SCORE in relation to the clinical and laboratory characteristics of patients is very heterogeneous, which leads to the presence of a residual risk of cardiovascular events. This category may include individuals with a family history of cardiovascular disease at a young age, with abdominal obesity (AO), endothelial dysfunction, and high levels of triglyceride-rich lipoproteins. In this regard, an active search is underway for new metabolic markers within the low cardiovascular risk group. <b>The purpose</b> of the study was to compare the nutrition, the adipose tissue distribution in low cardiovascular risk individuals, depending on the AO. <b>Material and methods</b>. The study included 86 healthy low risk (SCORE<1%) patients (mean age 42.6±2 years), who were divided into 2 groups: with AO [waist circumference (WC) >=94 cm in men and >=80 cm in women] - 44 patients (32% of men) and without AO - 42 patients (38% of men). The body composition was carried out using the bioimpedance analyzer. The distribution of ectopic fat deposits in the liver, pancreas and epicardial region was studied using ultrasound methods. A frequency questionnaire (Diet Risk Score) was used to assess nutrition. <b>Results</b>. In low risk patients with AO, signs of unhealthy diet are statistically significantly more common (in 52 in the main group vs 2% in the control group, p<0.01), ectopic deposition of adipose tissue in the liver (53 vs 9%, p<0.001), pancreas (56% in the main group, absent in the control group, p<0.001), epicardia l region (the epicardial fat thickness median is 4.24 mm in the main group vs 2.15 mm in the control group) compared with a control group. <b>Conclusion</b>. The low cardiovascular risk group is very heterogeneous. One of the markers of heterogeneity is central obesity - a marker of unhealthy diet, subclinical ectopic fat deposition and hypertriglyceridemia. Patients with AO of the low cardiovascular risk group require a more thorough examination with the obligatory determination of waist circumference, ultrasound assessment of the liver and pancreas parenchyma, and determination of the epicardial fat thickness. Using a short nutrition questionnaire allows you to quickly identify signs of unhealthy diet and discuss them with the patient.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 1","pages":"74-84"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9136741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Alternative protein sources: bacteria <i>Methylococcus capsulatus</i> concentrate, characteristic of composition and biological value].","authors":"E O Sadykova,&nbsp;M D Trebukh,&nbsp;N S Nikitin,&nbsp;S I Shestakova,&nbsp;A A Shumakova,&nbsp;M A Makarenko,&nbsp;N V Tyshko","doi":"10.33029/0042-8833-2023-92-3-36-44","DOIUrl":"https://doi.org/10.33029/0042-8833-2023-92-3-36-44","url":null,"abstract":"<p><p>A promising growth vector of food protein production in the context of the Russian Federation's food sovereignty security is the use of microbial synthesis. Taking into consideration the proven promising use of biotechnological processes in the production of alternative protein sources, modern scientific research is focused, among other issues, on improving the technology of obtaining food microbial protein using a variety of substrates and strains-producers, as well as evaluating the consumer properties, food, biological value and safety of such products. <b>The purpose</b> of the research was to study and comparatively evaluate protein concentrate (PC) from bacteria Methylococcus capsulatus and basic food of animal and plant origin within the development of the technology of optimal in nutritional and biological value PC production. <b>Material and methods</b>. Analysis of the nutritional and biological value of PC obtained from denucleinized and purified from cell walls biomass of methanoxidizing bacteria Methylococcus capsulatus (strain GSB-15) was carried out on 46 indicators, including estimation of protein content and amino acid composition, fat content and fatty acid composition, ash and moisture. Biological studies based on measuring of net protein ratio / net protein utilization were performed on 28 growing (between 25-50 days of life) male Wistar rats. Rats in the control group (n=14) received a semi-synthetic casein diet with a protein content of ~12% in calories, the test group (n=14) received a diet including an equivalent amount of PC protein. Body weight, feed intake, and fecal and urine nitrogen losses were measured during the experiment. The biological value and digestibility of protein were judged by coefficients of protein efficiency ratio, net protein ratio, true protein digestibility, true protein biological value, true net protein utilization. <b>Results</b>. The nutritional value study of PC showed high protein content - 69.0%, the share of fat, moisture and ash, accounted for 0.17, 9.5 and 14.4%, respectively. The carbohydrate content was 7.0% (of which mono- and disaccharides were <0.1%). The results of a comparative assessment of Methylococcus capsulatus protein amino acid profile and basic food of animal and plant origin showed a balanced content of the most amino acids, the level of which is comparable with the protein of chicken egg, which is traditionally a standard of quality of complete protein. At the same time, the content of the essential amino acid tryptophan in PC was an order of magnitude lower than in chicken egg protein; the content of this amino acid in PC is comparable with incomplete plant proteins (sunflower, flax, rapeseed). The results of the biological value evaluation of the Methylococcus capsulatus protein in the experiment on rats indicate a relatively low biological value of the microbial synthesis protein, that is caused, most likely, by tryptophan deficiency. Rats of the test group had a","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"92 3","pages":"36-44"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10171456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}