[非酒精性脂肪肝患者的营养结构与对健康最重要的营养模式的比较]。

Q2 Medicine
Voprosy pitaniia Pub Date : 2024-01-01 Epub Date: 2024-08-05 DOI:10.33029/0042-8833-2024-93-5-125-141
A A Goncharov, V I Pilipenko, V A Isakov
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引用次数: 0

摘要

非酒精性脂肪肝(NAFLD)患者的营养模式受损被认为是该病的原因之一,某些营养类型对非酒精性脂肪肝的发病率有明显的保护作用。本研究旨在将俄罗斯非酒精性脂肪肝患者的营养特征与保肝饮食模式(地中海饮食、素食、DASH 饮食)进行详细比较。材料和方法。研究材料采用了联邦营养、生物技术和食品安全研究中心在 2021 年至 2023 年期间对 613 名患者进行的检查数据。肝脏脂肪变性和纤维化阶段的评估采用振动控制瞬态弹性成像技术进行。患者被分为两组:非酒精性脂肪肝组(n=367)和对照组(n=205),这两组按性别、年龄和体重指数成对(n=77)。营养评估采用半定量方法,分析过去一个月的食物消耗量。将研究组的食物摄入量与与降低非酒精性脂肪肝风险相关的饮食模式的摄入量进行比较。结果。对非酒精性脂肪肝患者和对照组患者饮食中各组食物摄入量的分析表明,他们的摄入量与健康饮食金字塔和非酒精性脂肪肝保护性膳食模式推荐的摄入量不同,牛奶和乳制品(Me=0.8-1.1 vs 1.8-4.2 杯/天)、豆类(Me=0.16-1.19 vs 1.5-7.5 杯/天)、植物油[非酒精性脂肪肝患者的摄入量为 7.0 克/天,对照组患者的摄入量为 5.0 克/天(P=0.04) vs 24.0-40.0 克/天]、鱼和海鲜(Me=6.2-6.6 vs 6.3-17.6 盎司/周)、蔬菜(Me=1.9-2.0 vs 2.5-4.0 杯/天)、坚果和种子(Me=3.5 vs 4.5-11.1盎司/天)、过量食用 "肉、禽、蛋 "类产品(Me=3.0-4.1 vs 0.4-3.6盎司/天),水果和谷物的食用量也符合这些建议(以白面包和烘焙食品为代价)。结论:非酒精性脂肪肝患者需要改变饮食习惯。非酒精性脂肪肝患者需要改变习惯性营养结构,包括引入能够补充饮食中缺失营养素的特殊膳食食品,这些营养素对非酒精性脂肪肝有保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Comparison of the nutritional structure of patients with non-alcoholic fatty liver disease with the most significant nutrition patterns for health].

Impaired nutritional patterns in patients with non-alcoholic fatty liver disease (NAFLD) are considered to be one of the causes of the disease, with certain types of nutrition having a pronounced protective effect on the incidence of NAFLD. The aim of the study was to compare in detail the nutritional characteristics of Russian patients with NAFLD compared with hepatoprotective dietary patterns (Mediterranean, vegetarian diet, DASH diet). Material and methods. As the research material, data from the examination of 613 patients of the Federal Research Centre of Nutrition, Biotechnology and Food Safety, obtained in the period from 2021 to 2023, were used. The assessment of the stage of liver steatosis and fibrosis was carried out using vibration-controlled transient elastography. The patients were divided into 2 groups: the NAFLD group (n=367) and the control group (n=205), and pairs (n=77) of these groups were formed by gender, age and BMI. Nutrition was assessed using a semi-quantitative method of analyzing food consumption over the previous 1 month. Consumption of food groups by the studied groups was compared with intake in dietary patterns associated with reduced risk of NAFLD. Results. Analysis of the consumption of food groups in the diets of patients with NAFLD along with patients from the control group showed that their intake differed from the recommended levels of consumption according to the healthy eating pyramid and protective dietary patterns for NAFLD with lower consumption of milk and dairy products (Me=0.8-1.1 vs 1.8-4.2 cups/day), legumes (Me=0.16-1.19 vs 1.5-7.5 cups/day), vegetable oils [Me=7.0 g/day in patients with NAFLD and Me=5.0 g/day in patients from the control group (p=0.04) vs 24.0-40.0 g/day], fish and seafood (Me=6.2-6.6 vs 6.3-17.6 ounces/week), vegetables (Me=1.9-2.0 vs 2.5-4.0 cups/day), nuts and seeds (Me=3.5 vs 4.5-11.1 ounces/day), excessive consumption of products from the «meat, poultry, eggs» group (Me=3.0-4.1 vs 0.4-3.6 ounces/day), and corresponded to these recommendations in terms of the consumption of fruit and cereals (at the expense of white brea d and bakery products). Conclusion. Patients with NAFLD need to change the structure of habitual nutrition, including through the introduction of foods for special dietary uses capable of replenishing the missing nutrients in their diet, which have a protective effect against NAFLD.

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Voprosy pitaniia
Voprosy pitaniia Medicine-Medicine (all)
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