{"title":"[儿童营养中的维生素 K1 和 K2]。","authors":"V M Kodentsova, D V Risnik","doi":"10.33029/0042-8833-2024-93-5-6-13","DOIUrl":null,"url":null,"abstract":"<p><p>Vitamin K comes in several forms in foods. Phylloquinone (vitamin K1) is found in plant foods. Menaquinones (vitamin K2) are a class of vitamin K compounds found in animal products and fermented foods. <b>The purpose</b> of the research was to characterize the role of vitamins K1 and K2 in the nutrition of children and to assess vitamin K status in children. <b>Material and methods</b>. The literature review in recent years was carried out using the RSCI, Pubmed databases, as well as Google Scholar system using the keywords: «vitamin K», «vitamin K1», «vitamin K2», «menaquinone» and «phylloquinone» in combination with «children», or «breast milk». <b>Results</b>. Vitamins K1 and K2 are interchangeable in relation to the formation of blood coagulation factors, but the effectiveness of vitamin K2 is much higher in the posttranslational modification of extrahepatic proteins that provide antioxidant, epigenetic effects. Current vitamin K intake recommendations only apply to phylloquinone. Breastfed children are at risk for vitamin K deficiency, because breast milk content of vitamin K, mainly in the form of phylloquinone, is low. In adapted milk formulas for infant feeding, the content of vitamin K1 is significantly higher than in breast milk. To provide infants with vitamin K2, it is extremely important to promptly introduce complementary foods into the diet that are sources of menaquinones. Specifically formulated for the nutritional needs of young children products that contain naturally formed during milk fermentation vitamin K2, deserve special attention. <b>Conclusion</b>. Considering the important role of vitamin K in the prevention of the skeletal system and cardiovascular diseases, it is necessary to increase its consumption by including fermented foods naturally containing menaquinones (MK-7) in the diet.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"93 5","pages":"6-13"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Vitamins K<sub>1</sub> and K<sub>2</sub> in children's nutrition].\",\"authors\":\"V M Kodentsova, D V Risnik\",\"doi\":\"10.33029/0042-8833-2024-93-5-6-13\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Vitamin K comes in several forms in foods. Phylloquinone (vitamin K1) is found in plant foods. Menaquinones (vitamin K2) are a class of vitamin K compounds found in animal products and fermented foods. <b>The purpose</b> of the research was to characterize the role of vitamins K1 and K2 in the nutrition of children and to assess vitamin K status in children. <b>Material and methods</b>. The literature review in recent years was carried out using the RSCI, Pubmed databases, as well as Google Scholar system using the keywords: «vitamin K», «vitamin K1», «vitamin K2», «menaquinone» and «phylloquinone» in combination with «children», or «breast milk». <b>Results</b>. Vitamins K1 and K2 are interchangeable in relation to the formation of blood coagulation factors, but the effectiveness of vitamin K2 is much higher in the posttranslational modification of extrahepatic proteins that provide antioxidant, epigenetic effects. Current vitamin K intake recommendations only apply to phylloquinone. Breastfed children are at risk for vitamin K deficiency, because breast milk content of vitamin K, mainly in the form of phylloquinone, is low. In adapted milk formulas for infant feeding, the content of vitamin K1 is significantly higher than in breast milk. To provide infants with vitamin K2, it is extremely important to promptly introduce complementary foods into the diet that are sources of menaquinones. Specifically formulated for the nutritional needs of young children products that contain naturally formed during milk fermentation vitamin K2, deserve special attention. <b>Conclusion</b>. Considering the important role of vitamin K in the prevention of the skeletal system and cardiovascular diseases, it is necessary to increase its consumption by including fermented foods naturally containing menaquinones (MK-7) in the diet.</p>\",\"PeriodicalId\":23652,\"journal\":{\"name\":\"Voprosy pitaniia\",\"volume\":\"93 5\",\"pages\":\"6-13\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Voprosy pitaniia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33029/0042-8833-2024-93-5-6-13\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/16 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Voprosy pitaniia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33029/0042-8833-2024-93-5-6-13","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/16 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
食物中的维生素 K 有多种形式。植物醌(维生素 K1)存在于植物性食物中。甲萘醌(维生素 K2)是一类存在于动物产品和发酵食品中的维生素 K 化合物。研究的目的是确定维生素 K1 和 K2 在儿童营养中的作用,并评估儿童的维生素 K 状态。材料和方法。使用 RSCI、Pubmed 数据库以及谷歌学术系统对近年来的文献进行了回顾,关键词为"维生素 K"、"维生素 K1"、"维生素 K2"、"menaquinone "和 "phyloquinone",并结合 "儿童 "或 "母乳"。结果。维生素 K1 和 K2 在凝血因子的形成方面可以相互替代,但维生素 K2 在肝外蛋白质翻译后修饰方面的功效要高得多,可提供抗氧化和表观遗传效应。目前的维生素 K 摄入量建议仅适用于幽门螺杆菌。母乳喂养的儿童面临维生素 K 缺乏的风险,因为母乳中的维生素 K 含量较低,主要是以植物喹啉酮的形式存在。在婴儿配方奶粉中,维生素 K1 的含量明显高于母乳。为了给婴儿提供维生素 K2,在饮食中及时添加含有甲萘醌的辅食极为重要。为满足幼儿的营养需求而专门配制的、含有在牛奶发酵过程中自然形成的维生素 K2 的产品值得特别关注。结论考虑到维生素 K 在预防骨骼系统和心血管疾病方面的重要作用,有必要通过在饮食中添加天然含有月桂醌(MK-7)的发酵食品来增加维生素 K 的摄入量。
Vitamin K comes in several forms in foods. Phylloquinone (vitamin K1) is found in plant foods. Menaquinones (vitamin K2) are a class of vitamin K compounds found in animal products and fermented foods. The purpose of the research was to characterize the role of vitamins K1 and K2 in the nutrition of children and to assess vitamin K status in children. Material and methods. The literature review in recent years was carried out using the RSCI, Pubmed databases, as well as Google Scholar system using the keywords: «vitamin K», «vitamin K1», «vitamin K2», «menaquinone» and «phylloquinone» in combination with «children», or «breast milk». Results. Vitamins K1 and K2 are interchangeable in relation to the formation of blood coagulation factors, but the effectiveness of vitamin K2 is much higher in the posttranslational modification of extrahepatic proteins that provide antioxidant, epigenetic effects. Current vitamin K intake recommendations only apply to phylloquinone. Breastfed children are at risk for vitamin K deficiency, because breast milk content of vitamin K, mainly in the form of phylloquinone, is low. In adapted milk formulas for infant feeding, the content of vitamin K1 is significantly higher than in breast milk. To provide infants with vitamin K2, it is extremely important to promptly introduce complementary foods into the diet that are sources of menaquinones. Specifically formulated for the nutritional needs of young children products that contain naturally formed during milk fermentation vitamin K2, deserve special attention. Conclusion. Considering the important role of vitamin K in the prevention of the skeletal system and cardiovascular diseases, it is necessary to increase its consumption by including fermented foods naturally containing menaquinones (MK-7) in the diet.