Vox Sanguinis最新文献_第5页

Association of acute normovolemic hemodilution with hematologic inflammatory indices and early clinical outcomes after coronary artery bypass grafting. 冠状动脉搭桥术后急性等容血稀释与血液学炎症指标和早期临床结果的关系。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-09 DOI: 10.1111/vox.70371

Dilek Metin Yamac, Yadigar Yilmaz, Tuna Erturk, Hakan Emirkadi, Suheyla Abitagaoglu

{"title":"Association of acute normovolemic hemodilution with hematologic inflammatory indices and early clinical outcomes after coronary artery bypass grafting.","authors":"Dilek Metin Yamac, Yadigar Yilmaz, Tuna Erturk, Hakan Emirkadi, Suheyla Abitagaoglu","doi":"10.1111/vox.70371","DOIUrl":"https://doi.org/10.1111/vox.70371","url":null,"abstract":"Background and objectives: Acute normovolemic hemodilution (ANH) is an established patient blood management strategy in cardiac surgery, but its effects on postoperative inflammatory biomarkers remain unclear. In this study, we evaluate the association of ANH with inflammatory indices, lactate-to-albumin ratio, transfusion requirements, and early postoperative outcomes after coronary artery bypass grafting (CABG).Materials and methods: This retrospective, single-center study included 366 patients who underwent elective isolated CABG with cardiopulmonary bypass. Patients were assigned to an ANH group (n = 169) or a control group (n = 197). Primary outcomes were postoperative neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), neutrophil-to-monocyte-to-lymphocyte ratio (NMLR), and lactate-to-albumin ratio (LAR). Secondary outcomes included blood transfusion, intraoperative bleeding, mechanical ventilation, intensive care unit (ICU) stay and hospital stay, postoperative complications, and infections.Results: No significant differences were observed in NLR, PLR, or NMLR between the groups. LAR was significantly lower in the ANH group (0.31 ± 0.12 vs. 0.51 ± 0.93, p < 0.001). ANH was also associated with lower blood product utilization, reduced intraoperative bleeding, shorter duration of mechanical ventilation, shorter ICU stay and hospital stay, and lower rates of postoperative complications and infections (all p < 0.05).Conclusion: In patients undergoing CABG, ANH was associated with improved early postoperative outcomes and a lower LAR but not with significant changes in routine hematologic inflammatory indices. These findings suggest that the benefits of ANH may extend beyond blood conservation.","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to: Comment on 'Comparing specificity and seroconversion sensitivity among major blood screening assays for human immunodeficiency virus and viral hepatitis'. 对“比较人类免疫缺陷病毒和病毒性肝炎主要血液筛查方法的特异性和血清转换敏感性”的评论。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-08 DOI: 10.1111/vox.70323

Monica Chaves, Martina Schaetzl, Florina Pessl

引用次数: 0

Comment on "Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency". 评论“输血医学大数据与人工智能的应用：精准、安全、高效的机遇”

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-07 DOI: 10.1111/vox.70362

Jesse Qiao

引用次数: 0

International Forum on the Management of Donors Following Recurrent Quality Monitoring System Failures and Subsequent Discards: Responses. 质量监测系统经常失效和随后被抛弃后捐助者的管理国际论坛：回应。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-06 DOI: 10.1111/vox.70356

Champa Manchanayake, Jennie Haw, Shun Yin Kong, Cheuk Kwong Lee, Janaki Dissanayake, Trilitia Withanawasam, Ramir M Alcantara, Kalinga Perera, Maha A Badawi, Eman M Mansory, Salvador Oyonarte Gómez, Youssef Moatassim De la Torre, Daniele Prati, Elena Coluccio, Courtney K Hopkins, Ralph R Vassallo, Nicole Priddee, Fernanda Azevedo-Silva, Luiz de Melo Amorim Filho, M Suhail Asghar, Chiara Vendramin, Johnathan Mack, Evan Sharp, Aggrey Dhabangi, Ezra Musisi, Naoko Watanabe-Okochi, Yoshihiro Endo, Arwa Z Al-Riyami, Nancy Dunbar

引用次数: 0

International Forum on the Management of Donors Following Recurrent Quality Monitoring System Failures and Subsequent Discards: Summary. 质量监测系统经常性失效和随后被抛弃后捐助者管理国际论坛：摘要。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-06 DOI: 10.1111/vox.70357

Champa Manchanayake, Jennie Haw, Shun Yin Kong, Cheuk Kwong Lee, Janaki Dissanayake, Trilitia Withanawasam, Ramir M Alcantara, Kalinga Perera, Maha A Badawi, Eman M Mansory, Salvador Oyonarte Gómez, Youssef Moatassim De la Torre, Daniele Prati, Elena Coluccio, Courtney K Hopkins, Ralph R Vassallo, Nicole Priddee, Fernanda Azevedo-Silva, Luiz de Melo Amorim Filho, M Suhail Asghar, Chiara Vendramin, Johnathan Mack, Evan Sharp, Aggrey Dhabangi, Ezra Musisi, Naoko Watanabe-Okochi, Yoshihiro Endo, Arwa Z Al-Riyami, Nancy Dunbar

引用次数: 0

Optimization of platelet concentrate inventory management using a simple standardized decision-support model: A retrospective study from a Regional Blood Center. 使用简单的标准化决策支持模型优化血小板浓缩物库存管理：来自区域血液中心的回顾性研究。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-06 DOI: 10.1111/vox.70366

Anna Lizoń, Monika Marszałek, Wirginia Krzyściak

{"title":"Optimization of platelet concentrate inventory management using a simple standardized decision-support model: A retrospective study from a Regional Blood Center.","authors":"Anna Lizoń, Monika Marszałek, Wirginia Krzyściak","doi":"10.1111/vox.70366","DOIUrl":"https://doi.org/10.1111/vox.70366","url":null,"abstract":"Background and objectives: Platelet concentrates (PCs) are difficult to manage because of their short shelf-life and variable clinical demand. The aim of this study was to evaluate the impact of a modified platelet inventory management strategy at a Regional Blood Donation and Treatment Center on product utilization and expiration-related losses.Materials and methods: This retrospective observational study analyzed platelet inventory management from 2015 to 2025, focusing on changes introduced in 2024. The strategy included an Excel-based decision-support tool incorporating current inventory, predefined target stock levels, ABO distribution, and the use of group AB platelets as universal products. Apheresis platelet collection was also reorganized to improve supply flexibility.Results: Between 2015 and 2025, the number of transfused PCs increased from 8306 to 13,971 units/year (p < 0.001), while the outdate rate decreased from 1.86% to 0.04% (p = 0.0009). After 2023, apheresis platelets accounted for over 40% of issued products, and the mean use of group AB platelets increased from approximately 7% to over 12%. The mean age of transfused platelets increased from 2.38 ± 1.19 days in 2015-2023 to 2.62 ± 1.33 days in 2024-2025.Conclusion: Implementation of an integrated platelet inventory management strategy improved inventory utilization, substantially reduced expiration-related losses, and maintained supply despite increasing clinical demand. Simple decision-support tools combined with organizational changes may provide a practical approach to platelet inventory optimization in regional blood centers.","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating Australia's plasma pathway and rethinking transgender donor sexual activity restrictions: Zero donor detections of transfusion-transmissible infections in 6 months following changes to source plasma donation eligibility for sexual activity and HIV pre-exposure prophylaxis. 评估澳大利亚的血浆途径和重新思考跨性别献血者的性行为限制：在性行为和HIV暴露前预防的血浆捐赠来源改变后的6个月内，零献血者检测到输血传播感染。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-02 DOI: 10.1111/vox.70360

Charles Gilbert Viska, Anthea Cheng, Claire Styles, Bryant Koh, Skye McGregor, Veronica Hoad

{"title":"Evaluating Australia's plasma pathway and rethinking transgender donor sexual activity restrictions: Zero donor detections of transfusion-transmissible infections in 6 months following changes to source plasma donation eligibility for sexual activity and HIV pre-exposure prophylaxis.","authors":"Charles Gilbert Viska, Anthea Cheng, Claire Styles, Bryant Koh, Skye McGregor, Veronica Hoad","doi":"10.1111/vox.70360","DOIUrl":"https://doi.org/10.1111/vox.70360","url":null,"abstract":"Background and objectives: Sexual activity-based blood donation restrictions aim to reduce incident transfusion-transmissible infections (TTIs) but are not required for source plasma because of additional pathogen reduction. On 13 July 2025, Australian Red Cross Lifeblood introduced a plasma pathway (PP) allowing previously ineligible individuals to donate source plasma irrespective of recent sexual activity or human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) use. This study describes donor demographics and donation prevalence of tested TTIs from the program's first 6 months. Separately, associated PP changes facilitated a contemporary TTI prevalence estimate among transgender donors during this period.Materials and methods: Descriptive demographics and TTI results were extracted from identified cohort donors from 13 July 2025 to 13 January 2026. TTI prevalence (per 10,000 plasma donations) was estimated by detected TTIs divided by the total number of donations.Results: The PP supported 6673 donations from 7832 attendances by 3465 donors over 6 months. Zero (upper 95% confidence limit 6.94 per 10,000 donations) cases of HIV, hepatitis B virus or hepatitis C virus were detected. New donors constituted 40% of PP donors. Donations were predominantly from men reporting sex with men without (48%) or with PrEP use (30%). No TTIs (0, upper 95% confidence limit 25.76 per 10,000 donations) were detected from transgender donors during this period.Conclusion: TTI prevalence was lower than predicted. The PP demonstrates an inclusive way to limit restrictions on sexual activity and PrEP use without changing the safety profile. Other blood services should consider its introduction.","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148881306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motivational regulation for blood donation among Iranian blood donors: A nationwide mixed-effects study based on self-determination theory. 伊朗献血者献血动机调节：基于自我决定理论的全国性混合效应研究。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-02 DOI: 10.1111/vox.70364

Fahimeh Ranjbar Kermani, Sedigheh Amini Kafi-Abad

{"title":"Motivational regulation for blood donation among Iranian blood donors: A nationwide mixed-effects study based on self-determination theory.","authors":"Fahimeh Ranjbar Kermani, Sedigheh Amini Kafi-Abad","doi":"10.1111/vox.70364","DOIUrl":"https://doi.org/10.1111/vox.70364","url":null,"abstract":"Background and objectives: To investigate the hierarchical structure of blood donation motivation based on self-determination theory (SDT), specifically examining the associations between six regulatory styles-spanning the spectrum from amotivation to intrinsic motivation-and overall donor motivation.Materials and methods: A nationwide cross-sectional study across 31 Iranian provinces enrolled 7187 potential donors (92.4% response rate). Motivation was assessed using the 24-item Self-Regulation of Blood Donation Scale. Multivariable linear mixed-effects models, adjusted for demographic and behavioral confounders, were used for statistical analysis. Bonferroni-corrected pairwise comparisons elucidated the hierarchy, and multiple imputation addressed missing data.Results: Adjusted mean scores differed significantly across all six regulatory styles (all pairwise p < 0.001). Scores increased progressively across the SDT continuum, from amotivation (adjusted mean = 1.58) to intrinsic motivation (adjusted mean = 4.43). Intrinsic motivation had the highest adjusted score, followed by integrated, identified, introjected, and external regulation. The difference between intrinsic motivation and amotivation was 2.865 points (95% confidence interval [CI]: 2.826-2.904). Adjustment for demographic and donation-related characteristics produced minimal changes in the estimated differences. Sensitivity analyses using multiple imputation yielded comparable results.Conclusion: Iranian blood donors demonstrated a clear motivational hierarchy consistent with the SDT continuum, with the highest scores observed for intrinsic and other autonomous forms of motivation. These findings support the utility of SDT for characterizing blood donation motivation in Iran and suggest that donor retention strategies may benefit from approaches that support autonomy and the internalization of personally and socially meaningful reasons for donation.","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148881273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood donor safety and selection criteria for individuals self-identifying as trans or non-binary. 自我认同为跨性别或非二元的个体的献血者安全和选择标准。

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-01 Epub Date: 2026-06-04 DOI: 10.1111/vox.70301

Jean-François Leblanc, Catherine Thibeault, Christian Renaud, Antoine Lewin

{"title":"Blood donor safety and selection criteria for individuals self-identifying as trans or non-binary.","authors":"Jean-François Leblanc, Catherine Thibeault, Christian Renaud, Antoine Lewin","doi":"10.1111/vox.70301","DOIUrl":"10.1111/vox.70301","url":null,"abstract":"Social movements in favour of greater diversity, equity and inclusion have led societies to re-examine the concepts of sex assigned at birth and gender identity. These have also impacted healthcare systems and blood operators. Gender identities extending beyond the concept of cisgender binary individuals might have an impact on the safety of blood components for recipients, and on the safety of the donation process itself. Furthermore, the procedures put in place by blood operators to welcome donors from sexual and gender diversity might have a major impact on donors' psychological well-being and retention. This review provides an overview of the processes used by blood operators to mitigate potential health risks for both donors and recipients associated with trans and non-binary donors. It also examines how blood operators address sexual and gender diversity in the donor registration process. Regarding the theoretical risks of human immunodeficiency virus (HIV) transmission and of transfusion-related acute lung injury arising from trans donors, the available evidence suggests that the hypothetical increases would be negligible. Recent studies show that adapting the donor history questionnaire for sexual and gender diversity is still an ongoing process. Improvements are needed, especially in communication with stakeholders, staff training and reducing health risks for donors. The broadening of sexual and gender identities provides an opportunity for blood operators to act as agents of positive social change towards greater safety, diversity, equity and inclusion in our societies.","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":"1275-1289"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13563482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148164791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolving HIV-1 epidemiology, drug resistance and socio-demographics among blood donors in Dalian, Northeastern China, 2011-2024. 2011-2024年中国东北大连市献血者HIV-1流行病学演变、耐药性和社会人口统计学

IF 1.6 4区医学

Vox Sanguinis Pub Date : 2026-09-01 Epub Date: 2026-06-11 DOI: 10.1111/vox.70309

Xuelian Deng, Xiaohan Guo, Xiaochun Liu, Liang Zang, Yaxin Fan, Xiaohua Liang, Daniel Candotti

{"title":"Evolving HIV-1 epidemiology, drug resistance and socio-demographics among blood donors in Dalian, Northeastern China, 2011-2024.","authors":"Xuelian Deng, Xiaohan Guo, Xiaochun Liu, Liang Zang, Yaxin Fan, Xiaohua Liang, Daniel Candotti","doi":"10.1111/vox.70309","DOIUrl":"10.1111/vox.70309","url":null,"abstract":"Background and objectives: Human immunodeficiency virus type 1 (HIV-1) prevalence among Chinese blood donors has risen over recent decades, showing marked regional variation. Yet molecular epidemiology data among Chinese donors remain limited.Materials and methods: From 2011 to 2024, blood donations in Dalian, Liaoning Province, were screened using HIV antibody and antigen tests combined with multiplex nucleic acid testing. HIV-1 infection rates, molecular characteristics, genetic diversity, drug resistance and donor socio-demographics were analysed. Partial HIV-1 pol sequences were evaluated for drug resistance mutations (DRMs) using the Stanford HIV Drug Resistance Database algorithm.Results: The HIV-1 infection rate peaked at 55.3 per 100,000 donations in 2013 and stabilized at 12-21 per 100,000 in recent years. Most infected donors were young, male, single and first-time donors. Sexual transmission predominated, particularly among men who have sex with men (MSM) (49.8%), of whom 33.8% were repeat donors. Genetic analysis revealed substantial subtype diversity, dominated by CRF01_AE and CRF07_BC, with unique recombinant forms and occasional non-Asian subtypes. Molecular clustering suggested possible test-seeking behaviour. Notably, 6.8% of HIV-positive samples harboured DRMs, mainly against non-nucleoside reverse transcriptase inhibitors, indicating sporadic transmission of resistant strains.Conclusion: These findings underscore the need for strengthened pre-donation education and sustained HIV molecular surveillance to protect blood safety and inform public health strategies.","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":"1366-1375"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13563475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148219864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0