Vox SanguinisPub Date : 2026-09-16DOI: 10.1111/vox.70377
Takaaki Hato, Naoki Shimada
{"title":"Comment on: Risk of vasovagal reactions in sleep-deprived and fasting blood donors: Reply.","authors":"Takaaki Hato, Naoki Shimada","doi":"10.1111/vox.70377","DOIUrl":"https://doi.org/10.1111/vox.70377","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148983570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-15DOI: 10.1111/vox.70374
Cindy Tay, Laura K Dilly, Wen Lu, Kerry O'Brien, Hlaing Tint, Quentin Eichbaum
{"title":"Inter-institutional perspectives on usage of fibrinogen replacement therapies in North America.","authors":"Cindy Tay, Laura K Dilly, Wen Lu, Kerry O'Brien, Hlaing Tint, Quentin Eichbaum","doi":"10.1111/vox.70374","DOIUrl":"https://doi.org/10.1111/vox.70374","url":null,"abstract":"<p><strong>Background and objectives: </strong>Cryoprecipitated antihemophilic factor (cryoprecipitate), fibrinogen concentrate (FC), and pathogen-reduced cryoprecipitated fibrinogen complex (PR cryoprecipitate) are sources of fibrinogen replacement, and each has advantages and disadvantages in terms of cost, efficacy, safety, and logistics of administration. This study examines the respective utilization frequencies of these different products at institutions in North America and the factors influencing the decision on which one(s) to adopt.</p><p><strong>Materials and methods: </strong>A survey was distributed via email to contacts for Advancement of Blood and Biotherapies (AABB)-accredited blood banks/transfusion services. Survey questions covered topics including the availability and usage of FC, cryoprecipitate, and PR cryoprecipitate, as well as the perceived advantages of each product.</p><p><strong>Results: </strong>A total of 53 responses were received from surveyed institutions (estimated 25% response rate). Over half (31/53, 58.5%) of respondents exclusively used cryoprecipitate, 30.2% (16/53) used two sources of fibrinogen replacement, and 7.5% (4/53) used all three (cryoprecipitate, FC, and PR cryoprecipitate). More than half of the institutions restricted FC to specific indications, primarily for cost containment. The most commonly cited advantages of FC over cryoprecipitate were storage convenience and rapid reconstitution.</p><p><strong>Conclusion: </strong>Surveyed institutions in the United States and Canada primarily use cryoprecipitate for fibrinogen replacement, with variable usage of FC and limited usage of PR cryoprecipitate. The perception of FC being more expensive than cryoprecipitate predominated. Further studies comparing available fibrinogen replacement options would be valuable, particularly with consideration of product acquisition cost, wastage, impacts on utilization of other blood products, and patient outcomes.</p>","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-15DOI: 10.1111/vox.70376
Chi-Jen Huang, Lien-Chung Wei
{"title":"Comment on: Risk of vasovagal reactions in sleep-deprived and fasting blood donors.","authors":"Chi-Jen Huang, Lien-Chung Wei","doi":"10.1111/vox.70376","DOIUrl":"https://doi.org/10.1111/vox.70376","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-14DOI: 10.1111/vox.70372
Claude Tayou Tagny, Dora Mbanya
{"title":"Moving beyond the myth of \"cultural barriers\" in Sub-Saharan African blood donor recruitment.","authors":"Claude Tayou Tagny, Dora Mbanya","doi":"10.1111/vox.70372","DOIUrl":"https://doi.org/10.1111/vox.70372","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-14DOI: 10.1111/vox.70365
Sheharyar Raza, Ruchika Goel
{"title":"Response to comment on 'Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency'.","authors":"Sheharyar Raza, Ruchika Goel","doi":"10.1111/vox.70365","DOIUrl":"https://doi.org/10.1111/vox.70365","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-09DOI: 10.1111/vox.70367
Catherine A Hyland, Christoph Gassner, Jill R Storry
{"title":"The ISBT Blood Group Database: A digital resource for classifying blood groups in the genomic era.","authors":"Catherine A Hyland, Christoph Gassner, Jill R Storry","doi":"10.1111/vox.70367","DOIUrl":"https://doi.org/10.1111/vox.70367","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of acute normovolemic hemodilution with hematologic inflammatory indices and early clinical outcomes after coronary artery bypass grafting.","authors":"Dilek Metin Yamac, Yadigar Yilmaz, Tuna Erturk, Hakan Emirkadi, Suheyla Abitagaoglu","doi":"10.1111/vox.70371","DOIUrl":"https://doi.org/10.1111/vox.70371","url":null,"abstract":"<p><strong>Background and objectives: </strong>Acute normovolemic hemodilution (ANH) is an established patient blood management strategy in cardiac surgery, but its effects on postoperative inflammatory biomarkers remain unclear. In this study, we evaluate the association of ANH with inflammatory indices, lactate-to-albumin ratio, transfusion requirements, and early postoperative outcomes after coronary artery bypass grafting (CABG).</p><p><strong>Materials and methods: </strong>This retrospective, single-center study included 366 patients who underwent elective isolated CABG with cardiopulmonary bypass. Patients were assigned to an ANH group (n = 169) or a control group (n = 197). Primary outcomes were postoperative neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), neutrophil-to-monocyte-to-lymphocyte ratio (NMLR), and lactate-to-albumin ratio (LAR). Secondary outcomes included blood transfusion, intraoperative bleeding, mechanical ventilation, intensive care unit (ICU) stay and hospital stay, postoperative complications, and infections.</p><p><strong>Results: </strong>No significant differences were observed in NLR, PLR, or NMLR between the groups. LAR was significantly lower in the ANH group (0.31 ± 0.12 vs. 0.51 ± 0.93, p < 0.001). ANH was also associated with lower blood product utilization, reduced intraoperative bleeding, shorter duration of mechanical ventilation, shorter ICU stay and hospital stay, and lower rates of postoperative complications and infections (all p < 0.05).</p><p><strong>Conclusion: </strong>In patients undergoing CABG, ANH was associated with improved early postoperative outcomes and a lower LAR but not with significant changes in routine hematologic inflammatory indices. These findings suggest that the benefits of ANH may extend beyond blood conservation.</p>","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-08DOI: 10.1111/vox.70323
Monica Chaves, Martina Schaetzl, Florina Pessl
{"title":"Response to: Comment on 'Comparing specificity and seroconversion sensitivity among major blood screening assays for human immunodeficiency virus and viral hepatitis'.","authors":"Monica Chaves, Martina Schaetzl, Florina Pessl","doi":"10.1111/vox.70323","DOIUrl":"https://doi.org/10.1111/vox.70323","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-07DOI: 10.1111/vox.70362
Jesse Qiao
{"title":"Comment on \"Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency\".","authors":"Jesse Qiao","doi":"10.1111/vox.70362","DOIUrl":"https://doi.org/10.1111/vox.70362","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vox SanguinisPub Date : 2026-09-06DOI: 10.1111/vox.70356
Champa Manchanayake, Jennie Haw, Shun Yin Kong, Cheuk Kwong Lee, Janaki Dissanayake, Trilitia Withanawasam, Ramir M Alcantara, Kalinga Perera, Maha A Badawi, Eman M Mansory, Salvador Oyonarte Gómez, Youssef Moatassim De la Torre, Daniele Prati, Elena Coluccio, Courtney K Hopkins, Ralph R Vassallo, Nicole Priddee, Fernanda Azevedo-Silva, Luiz de Melo Amorim Filho, M Suhail Asghar, Chiara Vendramin, Johnathan Mack, Evan Sharp, Aggrey Dhabangi, Ezra Musisi, Naoko Watanabe-Okochi, Yoshihiro Endo, Arwa Z Al-Riyami, Nancy Dunbar
{"title":"International Forum on the Management of Donors Following Recurrent Quality Monitoring System Failures and Subsequent Discards: Responses.","authors":"Champa Manchanayake, Jennie Haw, Shun Yin Kong, Cheuk Kwong Lee, Janaki Dissanayake, Trilitia Withanawasam, Ramir M Alcantara, Kalinga Perera, Maha A Badawi, Eman M Mansory, Salvador Oyonarte Gómez, Youssef Moatassim De la Torre, Daniele Prati, Elena Coluccio, Courtney K Hopkins, Ralph R Vassallo, Nicole Priddee, Fernanda Azevedo-Silva, Luiz de Melo Amorim Filho, M Suhail Asghar, Chiara Vendramin, Johnathan Mack, Evan Sharp, Aggrey Dhabangi, Ezra Musisi, Naoko Watanabe-Okochi, Yoshihiro Endo, Arwa Z Al-Riyami, Nancy Dunbar","doi":"10.1111/vox.70356","DOIUrl":"https://doi.org/10.1111/vox.70356","url":null,"abstract":"","PeriodicalId":23631,"journal":{"name":"Vox Sanguinis","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}