Vascular Medicine最新文献

{"title":"Infective native visceral artery aneurysm (INVAA): A systematic review of etiology, treatment, and outcomes.","authors":"Mauricio Gonzalez-Urquijo, Gustavo Salgado-Garza, Ariana Marie Martin, Jos C van den Berg, Jose Francisco Vargas, Leopoldo Marine, Francisco Valdes, Mario Alejandro Fabiani","doi":"10.1177/1358863X251326537","DOIUrl":"10.1177/1358863X251326537","url":null,"abstract":"<p><p>The present review introduces the term 'infective native visceral artery aneurysm (INVAA)' and provides a systematic review of the literature on this topic. The terms 'mycotic' and 'infected' have been replaced by the term 'infective native' to more accurately describe aneurysms of this type. A systematic search of MEDLINE, Embase, Google Scholar, and Scopus databases was performed to identify articles reporting on INVAAs to April 2024. Inclusion criteria encompassed studies describing 'mycotic' or 'infected' primary visceral aneurysms, excluding patients with concurrent aneurysms in the aorta. The search yielded 356 articles, with 161 meeting the inclusion criteria, covering 175 patients. The median age was 48 years (IQR: 33-60 years), predominantly men (n = 127, 72.6%). INVAA was most frequently reported in the superior mesenteric artery (37.5%, <i>n</i> = 65), followed by the hepatic (22.9%, <i>n</i> = 40) and splenic arteries (14.3%, <i>n</i> = 25). Endocarditis was the predominant etiology in 67.4% (n = 118) of cases. Gram-positive pathogens were identified in 58.8% (n = 103) of cases. Treatment modalities included open surgery (49.7%, <i>n</i> = 87), endovascular interventions (37.7%, <i>n</i> = 66), and medical management (12.0%, <i>n</i> = 21). The overall proportion of patients who died was 13.7% (n = 24). In multivariable modeling, cerebral aneurysms (OR: 4.0, 95% CI 1.17, 12.8; <i>p</i> = 0.02), gastrointestinal bleed (OR: 5.79, 95% CI 1.86, 17.6; <i>p</i> < 0.01), and chronic kidney disease (OR: 16.0, 95% CI 2.3, 136; <i>p</i> < 0.01) were associated with increased odds of death. The optimal treatment for INVAA remains undefined, highlighting the need for standardization of reporting and prospective registries to enhance the understanding and management of this complex disease.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"510-521"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathological and clinical findings of calcified nodules in carotid artery stenosis: A study of 508 consecutive carotid endarterectomies.","authors":"Kiyofumi Yamada, Kinta Hatakeyama, Kisaki Amemiya, Masanori Kawasaki, Soichiro Abe, Hirotoshi Imamura, Hisae Mori, Manabu Shirakawa, Shinichi Yoshimura, Koji Iihara, Hiroharu Kataoka","doi":"10.1177/1358863X251324159","DOIUrl":"10.1177/1358863X251324159","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"485-487"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treated HIV infection is not associated with carotid vascular inflammation or plaque progression as assessed by dynamic contrast magnetic resonance imaging.","authors":"Saate Shakil, Daniel Chen, Daniel Isquith, Jamie Sapp, Isabella Pommier, Baocheng Chu, Yin Guo, Gador Canton, Niranjan Balu, Chun Yuan, Thomas Hatsukami, Charles Maynard, Xue-Qiao Zhao, Francis Kim","doi":"10.1177/1358863X251340633","DOIUrl":"10.1177/1358863X251340633","url":null,"abstract":"<p><strong>Background: </strong>Inflammation and immune dysregulation are thought to drive residual cardiovascular disease risk among persons living with human immunodeficiency virus (HIV) (PLWH) despite effective viral suppression with antiretroviral therapy (ART).</p><p><strong>Methods: </strong>We investigated differences in carotid inflammation and atherosclerosis in a longitudinal cohort of virally suppressed PLWH (<i>N</i> = 50; on stable ART with CD4 > 250 cells/mm³, viral load < 200 copies/mL for > 6 months) and HIV-uninfected controls (<i>N</i> = 51) matched for age, sex, hypertension, diabetes, smoking, hyperlipidemia, and family history of premature coronary artery disease (CAD). Participants were ≥ 40 years old at enrollment. Measures of carotid vascular inflammation (<i>K^trans</i>), neovascularization (<i>V_p</i>), and wall thickness were assessed at baseline, 1 year, and change over 1 year by dynamic contrast-enhanced magnetic resonance imaging (MRI).</p><p><strong>Results: </strong>Among 101 participants, 8% were women, 42% had hypertension, 52% had hyperlipidemia, 16% had diabetes, and 48% had a family history of CAD. Both PLWH and control participants demonstrated a reduction in systolic and diastolic blood pressures and total cholesterol over 1 year; however, the difference was not significant by HIV status. PLWH had a significant reduction in triglycerides compared with controls (-48.8 vs 12.8 mg/dL, <i>p</i> = 0.026). HIV was not associated with baseline, follow up, or change in markers of systemic inflammation assessed by plasma cytokines, nor vascular inflammation as assessed by <i>K^trans</i>, <i>V_p</i>, carotid wall thickness, or percent wall volume (a measure of plaque burden).</p><p><strong>Conclusion: </strong>In contrast to other studies of treated and virally suppressed PLWH, HIV infection was not associated with carotid inflammation or plaque in our hypothesis-generating study.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"449-459"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Active malignancy does not affect limb salvage and reocclusion in patients with acute limb ischemia: A single-center experience.","authors":"Edoardo Pasqui, Samira Bucelli, Leonardo Pasquetti, Cecilia Molino, Greta Ferraro, Gianmarco de Donato","doi":"10.1177/1358863X251351907","DOIUrl":"https://doi.org/10.1177/1358863X251351907","url":null,"abstract":"<p><p><b>Background:</b> This study aimed to assess the impact of active malignancy on outcomes in patients undergoing revascularization for acute limb ischemia (ALI), focusing on mortality, limb salvage, and patency loss. <b>Methods:</b> We conducted a retrospective analysis of consecutive patients with ALI who underwent lower-limb revascularization over a 7-year period. Patients were stratified into two groups based on the presence of active malignancy at ALI diagnosis. Kaplan-Meier analysis was used to assess survival, limb salvage, and freedom from reocclusion. Cox proportional hazards models were applied to identify independent predictors of mortality, major amputation, and reocclusion. <b>Results:</b> A total of 296 patients were included, with a mean age of 76.2 ± 12.6 years; 62.8% were men. Most occlusions involved the femoropopliteal segment (57.8%). Thirty-eight patients (12.8%) had active malignancy. Baseline characteristics, interventions, and 30-day outcomes were similar between groups. Over a median follow up of 29.8 ± 24.6 months, 140 deaths (47.3%) were recorded. Patients with malignancy had significantly worse survival (<i>p</i> = 0.005), but similar rates of limb salvage and freedom from reocclusion. In multivariable analysis, active malignancy was independently associated with higher mortality (OR 3.321, 95% CI 1.310-8.418, <i>p</i> = 0.01), but not with limb salvage or patency loss. <b>Conclusion:</b> Active malignancy is associated with increased mid- and long-term mortality in patients with ALI, yet limb-related outcomes remain comparable to nononcological patients. Aggressive revascularization strategies should not be withheld solely due to malignancy when clinically appropriate.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251351907"},"PeriodicalIF":3.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term results of the RANGER II SFA randomized trial of the Ranger drug-coated balloon vs standard percutaneous transluminal angioplasty for femoropopliteal artery treatment.","authors":"Ravish Sachar, Yoshimitsu Soga, Louis Lopez, Amane Kozuki, Marianne Brodmann, Vijay S Ramanath, Masahiko Fujihara, Anna M Chavez, Mohammad M Ansari, Thomas Zeller","doi":"10.1177/1358863X251349782","DOIUrl":"https://doi.org/10.1177/1358863X251349782","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251349782"},"PeriodicalIF":3.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144675927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for progression to chronic limb-threatening ischemia after endovascular therapy in patients with claudication.","authors":"Keisuke Shoji, Michitaka Kitamura, Shiori Yoshida, Yukinori Kato, Naotoshi Wada, Tetsuya Nomura, Natsuya Keira, Tetsuya Tatsumi","doi":"10.1177/1358863X251349771","DOIUrl":"https://doi.org/10.1177/1358863X251349771","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to evaluate the incidence and risk factors for progression to chronic limb-threatening ischemia (CLTI) in patients with peripheral artery disease (PAD) and de novo claudication who underwent endovascular therapy (EVT), particularly femoropopliteal intervention.</p><p><strong>Methods: </strong>A total of 338 limbs from consecutive patients with de novo claudication who received their first EVT were evaluated. The primary endpoint was progression to CLTI, assessed using the Kaplan-Meier estimate and hazard ratios (HRs) calculated via Cox regression analysis.</p><p><strong>Results: </strong>CLTI developed in 21 of 196 femoropopliteal interventions and four of 142 aortoiliac interventions. The median time from initial femoropopliteal intervention to CLTI onset was 2.4 years. Limbs treated with femoropopliteal intervention progressed to CLTI more often than those treated with aortoiliac intervention (estimated 10-year incidence: 15.3% vs 8.6%). Univariate analysis identified chronic kidney disease with or without hemodialysis (HR: 6.43; 95% CI: 2.02-24.1, HR: 3.13; 95% CI: 1.02-11.6), chronic heart failure (HR: 2.71; 95% CI: 1.14-6.55), severe calcification (HR: 2.98; 95% CI: 1.06-7.39), P2-3 segment intervention (HR: 4.72; 95% CI: 1.52-12.4), and poor infrapopliteal runoff (HR: 15.1; 95% CI: 5.06-64.7) as risk factors. Multivariate analysis showed poor infrapopliteal runoff as an independent predictor (HR: 11.2; 95% CI: 3.56-49.3).</p><p><strong>Conclusion: </strong>Progression to CLTI following femoropopliteal intervention in patients with claudication is influenced by comorbidities, vessel calcification, involvement of the P2-3 segment, and especially poor infrapopliteal runoff, regardless of EVT strategy.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251349771"},"PeriodicalIF":3.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical factors for predicting subsequent wound occurrence in the contralateral limb in patients with chronic foot wounds.","authors":"Shinsuke Kikuchi, Mitsuyoshi Takahara, Noriaki Maeshige, Yuma Sonoda, Hisae Hayashi, Nobuhide Kawabe, Keisuke Miyake, Chugo Rinoie, Nobuyoshi Azuma","doi":"10.1177/1358863X251351903","DOIUrl":"https://doi.org/10.1177/1358863X251351903","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251351903"},"PeriodicalIF":3.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CTA-based evaluation of carotid body size reveals associations with cardiovascular and metabolic conditions.","authors":"Ana Domínguez-Mayoral, María Prieto-León, David Núñez-Jurado, José Parada, Francisco Moniche, Irene Escudero-Martínez, Elena Zapata-Arriaza, Alejandro González-García, Dolors Giralt, Lucía Lebrato, Juan Antonio Cabezas-Rodríguez, Pilar Algaba, María Ángeles Sánchez-Armengol, José López-Barneo, Pilar Piñero, Soledad Pérez-Sánchez, Joan Montaner","doi":"10.1177/1358863X251349756","DOIUrl":"https://doi.org/10.1177/1358863X251349756","url":null,"abstract":"<p><strong>Background: </strong>The carotid body (CB) detects blood oxygen changes and may play a role in metabolic diseases. Several studies have suggested a link between CB size and cardiovascular conditions. This study aimed to evaluate CB size using computed tomography angiography (CTA) and investigate its associations with cardiovascular and metabolic conditions.</p><p><strong>Methods: </strong>A retrospective analysis of 279 patients undergoing CTA of the cervical vasculature was conducted. The CB was identified as an enhancing structure at the carotid bifurcation, and its area was measured on axial images. Clinical data, including comorbidities and vascular risk factors, were collected. Statistical analyses included univariate and stepwise multiple linear regression to identify significant predictors of CB size.</p><p><strong>Results: </strong>The CB was identified in 163 patients (49.1% right, 50.9% left). The mean CB area was 3.183 mm² for the right side and 2.901 mm² for the left. Obstructive sleep apnea (OSA) and internal carotid artery (ICA) stenosis ⩾ 70% were significant predictors of increased CB size. In the final regression model, OSA was associated with a 1.049 mm² increase in CB area (<i>p</i> = 0.027), whereas ICA stenosis ⩾ 70% and renin-angiotensin system inhibitor treatment were associated with increases of 0.528 mm² (<i>p</i> = 0.036) and 0.494 mm² (<i>p</i> = 0.037), respectively. CB hypertrophy was also associated with hypertension, obesity, and smoking in univariate analyses.</p><p><strong>Conclusions: </strong>This study highlights significant associations between CB hypertrophy and conditions such as OSA and ICA stenosis, suggesting that CB enlargement reflects the interplay between hypoxia, vascular pathology, and metabolic dysregulation. CTA may assess CB size as a cardiovascular biomarker.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251349756"},"PeriodicalIF":3.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Images in Vascular Medicine: Stenosis of the distal aorta unmasked by hemodynamic measures.","authors":"Martin Andrassy, Eric Secemsky, Grigorios Korosoglou","doi":"10.1177/1358863X251351553","DOIUrl":"10.1177/1358863X251351553","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251351553"},"PeriodicalIF":3.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Images in Vascular Medicine: Entrapment of dorsalis pedis artery upon plantar flexion of the foot.","authors":"Fei Wang, Libing Wei, Ran Liu, Lianrui Guo, Zhu Tong","doi":"10.1177/1358863X251349461","DOIUrl":"https://doi.org/10.1177/1358863X251349461","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251349461"},"PeriodicalIF":3.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}