Vestnik otorinolaringologii最新文献_第3页

[Hearing impairment in children with cystic fibrosis]. [囊性纤维化儿童的听力损害]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269101141

A I Kryukov, A Yu Ivoilov, N A Mileshina, N S Danilevskaya, M M Polunin, O I Simonova, K L Meshcheryakov, V N Sokolova, N Yu Kashirskaya, R A Zinchenko, V V Barilyak

{"title":"[Hearing impairment in children with cystic fibrosis].","authors":"A I Kryukov, A Yu Ivoilov, N A Mileshina, N S Danilevskaya, M M Polunin, O I Simonova, K L Meshcheryakov, V N Sokolova, N Yu Kashirskaya, R A Zinchenko, V V Barilyak","doi":"10.17116/otorino20269101141","DOIUrl":"10.17116/otorino20269101141","url":null,"abstract":"The process of hearing impairment in children suffering from cystic fibrosis remains one of the pressing problems for the scientific medical community today. The article examines the effect of systemic antibacterial therapy with aminoglycoside antibiotics on the auditory function of children with cystic fibrosis.Objective: To analyze the causes of hearing loss and the causes of hearing impairment in children with cystic fibrosis from antibacterial therapy with aminoglycoside antibiotics.Material and methods: Search for literature sources using the search engines PubMed, Web of Science and eLibrary.Results: A review of the literature shows that the acute problem of sensorineural hearing loss is associated with frequent use of aminoglycosides, and predictors of conductive hearing loss are inflammatory processes in the middle ear and eustachian tube. It has been demonstrated that not in all cases, antibacterial therapy with aminoglycoside antibiotics leads to hearing impairment, which demonstrates the urgent need to study the auditory function of children with cystic fibrosis and identify the characteristics of hearing impairment.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"41-49"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cholestaetoma of the frontal sinus in a child]. [儿童额窦胆瘘瘤]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino202691031107

U S Malyavina, Yu Yu Rusetsky, E N Latysheva, A N Bershina

引用次数: 0

[A clinical case of a neoplasm of chondrogenic origin in the area of the apex of the pyramid of the temporal bone in a child]. [儿童颞骨金字塔顶端区域软骨源性肿瘤的临床病例]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino202691021102

Kh M Diab, O A Pashinina, A M Shamkhalova

引用次数: 0

[Autoimmune hearing loss in giant cell arteritis: a clinical case]. 巨细胞动脉炎伴自身免疫性听力丧失1例

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269101186

I V Savenko, M Yu Boboshko, S V Bryzgalova

{"title":"[Autoimmune hearing loss in giant cell arteritis: a clinical case].","authors":"I V Savenko, M Yu Boboshko, S V Bryzgalova","doi":"10.17116/otorino20269101186","DOIUrl":"10.17116/otorino20269101186","url":null,"abstract":"Giant cell arteritis (GCA), also called as temporal arteritis, is a systemic vasculitis, primary affecting individuals over 50 years of age and mostly women. The disease can manifest with symptoms of systemic inflammatory response syndrome as well with symptoms of systemic vasculitis affecting mainly medium and large vessels, including branches of the carotid artery, first of all the ophthalmic and temporal. Pathogenetically, arterial damage in GCA is a combination of autoinflammatory and autoimmune processes, resulting in vascular wall remodeling with narrowing of the arterial lumen and subsequent ischemia in the affected organs and tissues. One of the uncommon symptoms of GCA, which in some cases may precede the onset of the disease, is cochleovestibular dysfunction, in particular sensorineural hearing loss, which might occur in 25-60% of GCA cases. The clinical case of untypical GCA was shown. The disease manifested after SARS-Cov-2 infection as the subacute rhinosinusitis and bilateral otitis media with effusion that finally resulted in profound mixed hearing loss. The clinical features of the disease looked like granulomatosis with polyangiitis, however, no increase in antinuclear and antineutrophil cytoplasmic antibody levels was detected. A specific clinical feature with unilateral vision loss after 12 months from the disease onset could help to verify it. Urgently corticosteroid therapy let us relieve both main symptoms and rhinosinusitis with bilateral otitis media with effusion that resulted in significant hearing improvement. It has been suggested that the combination of middle and inner ear lesions in this case could either be a consequence of the simultaneous development of GPA and GCA, or was the result of coincidence of a number of their pathogenesis links, specifically the activation of B cells, as well as excessive proliferation of monocytes/macrophages producing metalloproteinase-9.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"86-92"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Tinnitus compensation strategies based on the current neuroplasticity theories (systematic review)]. [基于当前神经可塑性理论的耳鸣补偿策略（系统综述）]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269102172

E Yu Tur, G Sh Tufatulin, V V Dvoryanchikov, S A Artyushkin

{"title":"[Tinnitus compensation strategies based on the current neuroplasticity theories (systematic review)].","authors":"E Yu Tur, G Sh Tufatulin, V V Dvoryanchikov, S A Artyushkin","doi":"10.17116/otorino20269102172","DOIUrl":"10.17116/otorino20269102172","url":null,"abstract":"Tinnitus is a serious medical and social problem of our time for many people, leading to significant psycho-emotional shock in some cases, disruption of social and professional adaptation. To date, there are several methods of treating tinnitus, the principle of which is based on pathogenetic concepts of brain neuroplasticity. The purpose of this work is to review existing tinnitus treatment methods from the point of view of modern neurophysiological concepts. Materials and methods: A keyword search and analysis of the works found in Russian and foreign databases (elibrary, CyberLeninka, PubMed, Scopus, Google Academic) over the past 5 years was carried out. A total of 387 keyword publications were found, and after eliminating duplicates and those that did not match the subject of the article, 21 papers were selected. Results. The use of non-medicinal tinnitus therapies such as sound therapy, transcranial magnetic stimulation, bimodal stimulation, and psychotherapeutic methods has shown statistically significant effectiveness in a number of systematic reviews and meta-analyses, both as part of monotherapy and as part of complex therapy aimed at retraining in tinnitus, which has shown the best results. The effectiveness of these methods has a neurophysiological explanation based on the neuroplasticity of the brain and the fact that changes occurring during the development of tinnitus can regress with certain measures. Thus, these options can be considered effective pathogenetic methods of treating tinnitus from the point of view of the principles of evidence-based medicine.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 2","pages":"72-77"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147875925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Medialization of the vocal fold in unilateral paresis and paralysis]. [单侧麻痹和麻痹的声带内侧化]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269104155

S A Karpishchenko, M A Ryabova, M Yu Ulupov, V A Stepanova

{"title":"[Medialization of the vocal fold in unilateral paresis and paralysis].","authors":"S A Karpishchenko, M A Ryabova, M Yu Ulupov, V A Stepanova","doi":"10.17116/otorino20269104155","DOIUrl":"https://doi.org/10.17116/otorino20269104155","url":null,"abstract":"Objective: To evaluate the safety and efficacy of injection laryngoplasty using calcium hydroxyapatite in patients with unilateral laryngeal paresis or paralysis.Material and methods: The study included a retrospective analysis of data from 27 patients (6 men, 21 women) who underwent this procedure between 2020 and 2025. In total, 39 procedures were performed in the study group under local or general anesthesia, 1-4 interventions per patient. The objective examination included computerized acoustic voice analysis with assessment of Jitter (%), Shimmer (%), and HNR (dB).Results: A statistically significant improvement in voice function was achieved: the median Jitter decreased from 2.4% to 1.0%, Shimmer from 12.7% to 5.2%, and HNR increased from 7.2 dB to 15.2 dB. Ultimately, permanent medialization was required in 3 patients due to unsatisfactory results; 1 patient developed a complication in the form of acute bacterial laryngitis with a pronounced systemic inflammatory reaction. In 8 cases, calcium hydroxyapatite injection was administered to patients in the early period (within 3 months) after the onset of vocal fold paresis. These patients had developed vocal fold paresis after thyroidectomy and required rapid voice restoration.Conclusion: Injection laryngoplasty using calcium hydroxyapatite significantly improves voice quality in patients with unilateral vocal fold mobility disorders.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 4","pages":"55-60"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Modern problems of diagnostics and treatment of laryngopharyngeal reflux disease]. 咽喉反流病的现代诊断与治疗问题

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269103177

N V Boiko, G V Shavkuta, A A Khanavirov

{"title":"[Modern problems of diagnostics and treatment of laryngopharyngeal reflux disease].","authors":"N V Boiko, G V Shavkuta, A A Khanavirov","doi":"10.17116/otorino20269103177","DOIUrl":"10.17116/otorino20269103177","url":null,"abstract":"The concept of extraesophageal symptoms secondary to GERD is complex and often controversial, leading to diagnostic and therapeutic challenges. Many researchers consider them to be a manifestation of an independent disease - laryngopharyngeal reflux disease (LPRD).The aim of the work is to provide a review of existing literature regarding the mechanisms, diagnostics and treatment of LPRD.Material and methods: A bibliographic research was conducted in the RSCI, PubMed, ScienceDirect databases.Results: Currently, there is no single diagnostic tool to determine unambiguously the relationship between typical symptoms of laryngopharyngeal reflux and gastroesophageal reflux disease (GERD). Determining the contribution of GERD to their development is based on the results of a comprehensive examination of the patient and his response to anti-reflux therapy. The peculiarities of the pathophysiological mechanisms of LPRD (a high percentage of non-acidic, mixed, as well as liquid and/or gas reflux, low resistance of the pharyngeal and upper respiratory tract mucosa to the damaging effect of refluxate) explain the need for treatment approaches that are different from those used for GERD. Lifestyle modification and anti-reflux diet give more predictable results in the treatment of LPRD than drug therapy.Prospects for increasing the effectiveness of drug treatment of diseases caused by regurgitation of gastric contents (LPRD, GERD) involve their phenotyping, as well as the development of interdisciplinary approach.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 3","pages":"77-84"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148377168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Improvement of objective diagnostic methods for acute rhinosinusitis]. 急性鼻窦炎客观诊断方法的改进

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269104188

A Yu Ovchinnikov, M A Edzhe, T Yu Sokaeva

{"title":"[Improvement of objective diagnostic methods for acute rhinosinusitis].","authors":"A Yu Ovchinnikov, M A Edzhe, T Yu Sokaeva","doi":"10.17116/otorino20269104188","DOIUrl":"https://doi.org/10.17116/otorino20269104188","url":null,"abstract":"Objective: To evaluate the diagnostic significance of nasal fractional exhaled nitric oxide (nFeNO) in patients with acute rhinosinusitis (ARS) and determine its relationship with clinical and instrumental parameters.Material and methods: The study included 44 patients with moderate acute rhinosinusitis and 33 healthy volunteers. The nFeNO level was measured using a portable electrochemical gas analyzer (NOBreath). Endoscopic assessment was performed using the modified Lund-Kennedy scale (m-LK), radiological assessment using the Lund-Mackay scale (LM), and symptom severity assessment using the SNOT-22 questionnaire. Measurements were performed at baseline, on days 7-10, and on days 30-35 of treatment.Results: Baseline nFeNO levels in ARS patients were significantly lower than in the control group (p<0.05). In unilateral lesions, decreased nFeNO levels were observed both on the affected and contralateral sides. During treatment, nFeNO levels increased and reached values comparable to the control group by days 30-35 (p>0.05). A stable negative correlation of moderate to high strength was found between nFeNO levels and the severity of clinical and radiological changes assessed by the m-LK and LM scales. The correlation with SNOT-22 scores was weak.Conclusion: NFeNO is a non-invasive biomarker of inflammation in ARS reflecting the severity of the pathological process and may be used for objective assessment of disease progression and treatment efficacy.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 4","pages":"88-91"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Semi-occluded vocal tract exercises improvement in patients after laryngeal and hypopharyngeal cancer treatment]. [喉下咽癌治疗后半封闭声道运动的改善]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269104150

N A Daikhes, V V Vinogradov, S S Reshulskiy, M L Isaeva, A S Korobkin, E B Fedorova, O M Larina, R R Khabiev, K V Mishchenko, S M Kochieva, A I Gafurova

{"title":"[Semi-occluded vocal tract exercises improvement in patients after laryngeal and hypopharyngeal cancer treatment].","authors":"N A Daikhes, V V Vinogradov, S S Reshulskiy, M L Isaeva, A S Korobkin, E B Fedorova, O M Larina, R R Khabiev, K V Mishchenko, S M Kochieva, A I Gafurova","doi":"10.17116/otorino20269104150","DOIUrl":"https://doi.org/10.17116/otorino20269104150","url":null,"abstract":"Introduction: The internal and external head and neck lymphedema is one of the consequences of surgical and radiation treatment of laryngopharyngeal cancer. The current task is to develop lymphatic drainage techniques that are effective for internal lymphedema.Objective: To evaluate semi-occluded vocal tract exercises effectiveness for internal lymphedema rehabilitaion in patients with laryngopharyngeal cancer.Material and methods: 64 patients with laryngopharyngeal cancer received radiation therapy in a single regime or as part of the combined treatment after surgery were included. All of them had internal lymphedema symptoms. Patients were stratified into 2 equal groups: group 1 was treated with conservative treatment. In group 2 semi-occluded vocal tract exercises were added to inhalation therapy.Results: In group 2 there was a reliable decrease of mucus and moth in the larynx (p=0.0039) and reduction of saliva delay in the larynx and piriform sinuses (p=0.0008), as well as reliably better dynamics of the indicators as a subjective assessment of symptoms associated with swallowing and voice disorders by the patient, as well as voice quality by a ENT specialist using GRBAS.Conclusion: The application of exercises with semi-occlusion of the vocal tract in combination with local anti-inflammatory, mucolytic therapy demonstrates effectiveness in the comprehensive treatment of internal lymph-discharge ENT organs.","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 4","pages":"50-54"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The high bulb of the internal jugular vein in otosurgery: a literature review]. [耳外科颈内静脉高球：文献综述]。

Vestnik otorinolaringologii Pub Date : 2026-01-01 DOI: 10.17116/otorino20269104199

N A Daikhes, A S Yunusov, I D Mukhmadov, H M Diab, V A Saidulaev, V P Shpotin

引用次数: 0