Vestnik otorinolaringologii最新文献

{"title":"[Etymology of the auditory ossicles names in the work \"Onomatologia anatomica\" by Josef Hyrtl].","authors":"S A Kutia, N G Nikolaeva, Yu Yu Abrosimov","doi":"10.17116/otorino20259002151","DOIUrl":"https://doi.org/10.17116/otorino20259002151","url":null,"abstract":"<p><p>The article represents translation of chapters of the scientific work \"Onomatologia anatomica\" (1880) by the Austrian physician and anatomist Josef Hyrtl, devoted to terminology used in the description of the auditory ossicles, namely \"Malleus\", \"Incus\", \"Stapes\".</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical case of unilateral tinnitus and pathology of the main vessels of the neck].","authors":"Kh T Abdulkerimov, K I Kartashova, R S Davydov, Z Kh Abdulkerimov, A V Egorushkina","doi":"10.17116/otorino20259002179","DOIUrl":"https://doi.org/10.17116/otorino20259002179","url":null,"abstract":"<p><p>Tinnitus (tinnitus) refers to the earliest and most common pathological symptoms of a number of diseases of the organ of hearing, as well as diseases and functional disorders of other organs and systems. The purpose of this publication is to draw the attention of practicing physicians (otorhinolaryngologists, internists, neurologists) to such a symptom as unilateral tinnitus, which in the presented clinical case was the result of dissection of the internal carotid artery. Additional diagnostic measures carried out in a timely manner, a multidisciplinary approach, and the use of modern radiation research methods made it possible to carry out early diagnosis of internal carotid artery dissection and prevent such severe complications as stroke, cerebrovascular accident, and arterio-arterial embolism.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Malignization of sinonasal inverted papilloma: literature review and clinical case].","authors":"K E Klimenko, Yu Yu Rusetsky, V S Zakharov","doi":"10.17116/otorino20259002183","DOIUrl":"https://doi.org/10.17116/otorino20259002183","url":null,"abstract":"<p><p>Inverted papilloma (SIP) is a relatively rare benign epithelial tumor of the nasal cavity which characterized by an aggressive course with local destruction of surrounding structures, a tendency to recurrence and associated with malignancy. Etiology remains little understood. SIPs is most commonly associated with human papillomavirus (HPV) and mutations in the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) genes, which are upregulated in recurrent SIPs.These factors are responsible for theinverted papilloma transformation into squamous cell carcinoma (SCC). Prognosis of sinonasal SCC is poor, in most cases likely owing to its advanced stage at presentation. Treatment includes complete SIP removal by endoscopic approach with histological examination. Follow-up of these patients is critical to diagnosing relapse, which can be either early or late. It is important to diagnose recurrence to enable early treatment, especially in case of associated carcinoma or malignancy. In case of SCC, additional radiotherapy and/or neoadjuvant chemotherapy is needed, because it shows promising results in improving outcomes. In this article, we present a clinical case of managing a patient with malignancy of inverted papilloma, which led to extensive destruction.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Immunotherapy in the treatment of chronic polypous rhinosinusitis with comorbid bronchial asthma].","authors":"E V Bezrukova, S A Artyushkin, E A Varyushina, A S Simbirtsev","doi":"10.17116/otorino20259001129","DOIUrl":"10.17116/otorino20259001129","url":null,"abstract":"<p><p>The leading factors in the pathogenesis of chronic polyposis rhinosinusitis (CRSwNP) are dysfunction of the epithelial barrier of the nasal and sinus mucosa and dysregulation of the immune system, both at the systemic and local levels. A Th2-mediated immune response plays a central role in the development of disease in patients with CRSwNP CRPS, and CRSwNP is often associated with bronchial asthma (BA). At the present time, for the conservative treatment of patients with CRSwNP+BA, preference is given to drug therapy aimed at the correction of mucosal immunity. The use of interferon α2β (IFN α2β) and the dipeptide γ-D-glutamyl-L-tryptophan may reduce the severity of the long-term local inflammatory process. However, the clinical efficacy of these drugs in the context of chronic polyposis has not been studied. The aim of this study was to compare the efficacy of topical application of recombinant IFN α2β, recombinant IFN α2β in combination with γ-D-glutamyl-L-tryptophan and IL-4Rα receptor inhibitor in the treatment of patients with CRSwNP+BA. The patients were divided into three groups. In the first group (31 people), 1 million units of interferon alpha2b were injected into the polyposis tissue for five days. In the second group (31 people), interferon alpha2b at a dose of 1 million units and gamma-D-glutamyl-L-tryptophan at a dose of 0.1 mg were injected into the polypous tissue for five days. To assess the dynamics of clinical symptoms in the reference group (31 people), a drug with a known mechanism of action and efficacy - a genetically engineered IL-4Rα receptor inhibitor - was used. This drug was used 300 mg once every 2 weeks subcutaneously for 1 year. The obtained results showed that recombinant IFN α2β in combination with γ-D-glutamyl-L-tryptophan are pathogenetically appropriate preparations for conservative treatment of patients with the following initial indicators: severity of the polyposis process - 2.2+0.2 points, swelling - 2.8+0.4 points, and amount of discharge - 2.9+0.3 points. A single 5-day course of the above-mentioned preparations had a positive therapeutic effect, which was accompanied by a pronounced reduction in the clinical symptoms of the disease: the volume of polyposis tissue, nasal breathing difficulties and swelling of the nasal mucosa after one month and was maintained for one year. At the same time, the results of our study indicate the necessity of a longer period of application of recombinant IFN α2β in combination with γ-D-glutamyl-L-tryptophan in patients with CRSwNP+BA. The data obtained were comparable to the corresponding indicators when using the IL-4Ra inhibitor. In our opinion, the mechanism of action of the preparations is associated with a decrease in the activity of inflammatory and proliferative processes in the nasal and sinus mucosa.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Implantation and transplantation materials in plastic closure of nasal septum perforation (literature review)].","authors":"E V Nosulya, N V Borovkova, A S Tovmasyan, I N Ponomarev, T A Aleksanyan, M Yu Polyaeva, A E Kishinevskiy, I G Kolbanova, V V Mosin, N V Shvedov","doi":"10.17116/otorino20259002155","DOIUrl":"10.17116/otorino20259002155","url":null,"abstract":"<p><p>The annual increase in the number of operations for the curvature of the nasal septum is accompanied by a proportional increase in the number of complications, for example, the development of nasal septum perforation (NSP). The frequency of NSP detection varies from 0.5% to 8%. In 60% of cases, NSP is defined as iatrogenic and is the result of surgical treatment or injury to the nose. In 12-47% of cases, NSP is idiopathic and develops as a result of chronic subatrophic rhinitis, uncontrolled use of intranasal decongestants and topical glucocorticosteroids, and in rare cases it is a manifestation of systemic diseases. The tactics of surgical treatment of NSP is a highly debatable issue. Historically, the treatment of nasal septum defects has evolved from the lengthening of small \"whistling\" perforations to the development of autoloscutes of the mucous membrane to perform plastic closure of nasal septum perforation. Studies conducted over the past 20 years have shown that the use of displaced vascularized mucosal flaps is the most effective method of surgical treatment of NSP. The effectiveness of this approach over the past 10 years has ranged from 70% to 90%. However, plastic closure of perforation with mucosal flaps is a very complex and labor-intensive process, it is possible provided the surgeon is highly qualified and has extensive experience, and careful care is provided during a long rehabilitation period. Modern research on the treatment and rehabilitation of patients with NSP is aimed at improving the effectiveness of the surgical stage, simplifying the surgical procedure, and shortening the rehabilitation period through the use of transplant materials and cellular technologies. Based on this, the purpose of our work was to analyze domestic and foreign studies on the use of biotechnological approaches in the closure of nasal septum defects.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"55-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diagnosis of labyrinth hydrops in patients on different stages of Meniere's disease].","authors":"N L Kunelskaya, E A Manaenkova, Yu V Levina, E V Baybakova, E V Larionova","doi":"10.17116/otorino20259003124","DOIUrl":"https://doi.org/10.17116/otorino20259003124","url":null,"abstract":"<p><strong>Objective: </strong>To calculate the sensitivity (Se) and specificity (Sp) indicators of clinical and instrumental diagnostic methods of labyrinth hydrops (LH) in patients with definite Meniere's disease (MD, according to the EAONO classification, 2015).</p><p><strong>Materials: </strong>We examined 67 patients with definite MD: stage 1 - 24, stage 2 - 23, stage 3 - 20 patients, as well as 30 subjects with sensorineural hearing loss (control group) with tone hearing thresholds similar to those in patients with MD.</p><p><strong>Study methods: </strong>Clinical, otorhinolaryngological, otoneurological (using audiometric and vestibulometric tests) examinations, extratympanic electrocochleography, glycerol dehydration test. Statistical analysis of obtained results was performed with Statistica software package (version 10.0.1011).</p><p><strong>Results: </strong>It has been established that Se and Sp indicators of clinical and instrumental tests in patients with definite MD and confirmed LH depend on the disease stage according to neurovisualization data. Electrocochleography, audiometric curve type (ascending) and dehydration test are the most sensitive and specific for detection of LH at the first stage of MD (96%); electrocochleography, ultrasound audiometry, caloric and video impulse tests (their dissociation) - at the second stage of MD (96%); audiometric curve type (horizontal), caloric and video impulse tests and vHIT (their dissociation), registration of cervical vestibular evoked myogenic potentials (their asymmetry) - at the third stage of MD (95%).</p><p><strong>Conclusions: </strong>The obtained results allow to optimize the diagnostic algorithm at suspicion on LH, as well as to reduce economic costs by eliminating test with low sensitivity and weak informativity.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 3","pages":"24-29"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Chorda tympani in the practice of an otosurgeon. Literature review].","authors":"N A Daikhes, A S Yunusov, V A Saidulaev, V P Shpotin, I D Mukhmadov","doi":"10.17116/otorino20259004172","DOIUrl":"10.17116/otorino20259004172","url":null,"abstract":"<p><p>The chorda tympani is one of the most traumatic anatomical structures during surgical interventions on the middle ear. The problem of intraoperative damage to the chorda tympani remains underestimated by otosurgeons due to its insufficient coverage in the medical literature. A search and analysis of modern scientific publications from publicly available information resources was conducted, including review articles, original research, monographs, observations of clinical cases, and textbooks from domestic and foreign authors. The anatomical and topographic features that contribute to the injury of the chorda tympani as well as clinical manifestations and diagnostic criteria for its damage are described. A correlation between the method of surgical intervention on the middle ear and the nerve trauma is reported. A thorough study of the structural features of the chorda tympani before surgery, as well as improvement of its reconstruction methods, will improve the quality of surgical treatment and the quality of life of patients.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 4","pages":"72-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Infiltrative-ulcerative lesion of the larynx in Behcet's disease].","authors":"S G Romanenko, O G Pavlikhin, D I Kurbanova, E V Lesogorova, O V Eliseev, E N Krasilnikova, E A Safyannikova, A V Efremenkova","doi":"10.17116/otorino202590041112","DOIUrl":"10.17116/otorino202590041112","url":null,"abstract":"<p><p>The article describes a clinical case of differential diagnostic search for the cause of infiltrative ulcerative laryngitis in a young patient. Infectious, systemic, and neoplastic causes are excluded. Behcet's disease was diagnosed 11 years after the first clinical signs appeared. In this case, the difficulty of diagnosis is due to the absence of typical signs of the disease.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 4","pages":"112-114"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Plastic perforation of the nasal septum with a flap on the branches of the superior labial artery].","authors":"Yu Yu Rusetsky, V A Stepanova, J T Mokoyan, V M Svistushkin, A N Yelumeeva, A N Shcheglov","doi":"10.17116/otorino20259002126","DOIUrl":"https://doi.org/10.17116/otorino20259002126","url":null,"abstract":"<p><p>An innovative method of endonasal closure of postoperative perforations of the nasal septum is presented, which is based on the use of a mucoperiosteal flap formed on the branches of the superior labial artery. Since 2023, the described technique has been used in 15 patients (average age 43 years). The duration of postoperative follow-up varies from 4 to 9 months. The assessment of the quality of life of patients before and after surgery was carried out using the SNOT-22 questionnaire. The average duration of the operation was 60 minutes. In 14 (93.3%) of the 15 patients, complete anatomical closure of the perforation was achieved. Complete healing of the donor area was noted 1 month after the operation. There were no postoperative complications (bleeding, infections). The average score for SNOT-22 decreased from 42.3±1.65 to 12.02±2.30 points 3-6 months after surgery (<i>p</i><0.05), indicating a significant improvement in the quality of life of patients. The high efficiency of the proposed method is demonstrated. The technical accessibility and prospects for wide application in surgical practice are noted. Further studies in large groups of patients are needed to definitively determine the place of this method in surgery for closing nasal septum perforations.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"26-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Doctors-participants of the Great Patriotic War. Talyshinskiy A.M.o - senior doctor of Air Defence Artillery Division, Captain of the Medical Service. To 100th birthday anniversary of Grand PhD in Medical sciences, Professor Talyshinskiy A.M.o.]","authors":"L N Starkova, N A Pikhtileva, T I Karaseva","doi":"10.17116/otorino2025900315","DOIUrl":"https://doi.org/10.17116/otorino2025900315","url":null,"abstract":"<p><p>The founder of the Ryazan scientific and practical school of otorhinolaryngology, Talyshinsky Abas Mehdi-ogly was a prominent Russian otorhinolaryngologist, doctor of medical sciences, professor, holder of the Order \"For Merit to the Fatherland\" II degree, participant of the Great Patriotic War, head of the Department of Otorhinolaryngology at the Ryazan Medical Institute named after Academician I.P. Pavlov in 1964-1989. During this period, the full scope of ENT surgeries and oncologic care was introduced in Ryazan otorhinolaryngology. Professor Talyshinsky was the first in Russia to use the technique of general anesthesia in outpatient otorhinolaryngologic surgeries. He is also a pioneer in the development of methods for surgical treatment of snoring.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 3","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}