Vestnik otorinolaringologii最新文献

{"title":"[Implantation and transplantation materials in plastic closure of nasal septum perforation (literature review)].","authors":"E V Nosulya, N V Borovkova, A S Tovmasyan, I N Ponomarev, T A Aleksanyan, M Yu Polyaeva, A E Kishinevskiy, I G Kolbanova, V V Mosin, N V Shvedov","doi":"10.17116/otorino20259002155","DOIUrl":"https://doi.org/10.17116/otorino20259002155","url":null,"abstract":"<p><p>The annual increase in the number of operations for the curvature of the nasal septum is accompanied by a proportional increase in the number of complications, for example, the development of nasal septum perforation (NSP). The frequency of NSP detection varies from 0.5% to 8%. In 60% of cases, NSP is defined as iatrogenic and is the result of surgical treatment or injury to the nose. In 12-47% of cases, NSP is idiopathic and develops as a result of chronic subatrophic rhinitis, uncontrolled use of intranasal decongestants and topical glucocorticosteroids, and in rare cases it is a manifestation of systemic diseases. The tactics of surgical treatment of NSP is a highly debatable issue. Historically, the treatment of nasal septum defects has evolved from the lengthening of small \"whistling\" perforations to the development of autoloscutes of the mucous membrane to perform plastic closure of nasal septum perforation. Studies conducted over the past 20 years have shown that the use of displaced vascularized mucosal flaps is the most effective method of surgical treatment of NSP. The effectiveness of this approach over the past 10 years has ranged from 70% to 90%. However, plastic closure of perforation with mucosal flaps is a very complex and labor-intensive process, it is possible provided the surgeon is highly qualified and has extensive experience, and careful care is provided during a long rehabilitation period. Modern research on the treatment and rehabilitation of patients with NSP is aimed at improving the effectiveness of the surgical stage, simplifying the surgical procedure, and shortening the rehabilitation period through the use of transplant materials and cellular technologies. Based on this, the purpose of our work was to analyze domestic and foreign studies on the use of biotechnological approaches in the closure of nasal septum defects.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"55-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Etymology of the auditory ossicles names in the work \"Onomatologia anatomica\" by Josef Hyrtl].","authors":"S A Kutia, N G Nikolaeva, Yu Yu Abrosimov","doi":"10.17116/otorino20259002151","DOIUrl":"https://doi.org/10.17116/otorino20259002151","url":null,"abstract":"<p><p>The article represents translation of chapters of the scientific work \"Onomatologia anatomica\" (1880) by the Austrian physician and anatomist Josef Hyrtl, devoted to terminology used in the description of the auditory ossicles, namely \"Malleus\", \"Incus\", \"Stapes\".</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical case of unilateral tinnitus and pathology of the main vessels of the neck].","authors":"Kh T Abdulkerimov, K I Kartashova, R S Davydov, Z Kh Abdulkerimov, A V Egorushkina","doi":"10.17116/otorino20259002179","DOIUrl":"https://doi.org/10.17116/otorino20259002179","url":null,"abstract":"<p><p>Tinnitus (tinnitus) refers to the earliest and most common pathological symptoms of a number of diseases of the organ of hearing, as well as diseases and functional disorders of other organs and systems. The purpose of this publication is to draw the attention of practicing physicians (otorhinolaryngologists, internists, neurologists) to such a symptom as unilateral tinnitus, which in the presented clinical case was the result of dissection of the internal carotid artery. Additional diagnostic measures carried out in a timely manner, a multidisciplinary approach, and the use of modern radiation research methods made it possible to carry out early diagnosis of internal carotid artery dissection and prevent such severe complications as stroke, cerebrovascular accident, and arterio-arterial embolism.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Malignization of sinonasal inverted papilloma: literature review and clinical case].","authors":"K E Klimenko, Yu Yu Rusetsky, V S Zakharov","doi":"10.17116/otorino20259002183","DOIUrl":"https://doi.org/10.17116/otorino20259002183","url":null,"abstract":"<p><p>Inverted papilloma (SIP) is a relatively rare benign epithelial tumor of the nasal cavity which characterized by an aggressive course with local destruction of surrounding structures, a tendency to recurrence and associated with malignancy. Etiology remains little understood. SIPs is most commonly associated with human papillomavirus (HPV) and mutations in the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) genes, which are upregulated in recurrent SIPs.These factors are responsible for theinverted papilloma transformation into squamous cell carcinoma (SCC). Prognosis of sinonasal SCC is poor, in most cases likely owing to its advanced stage at presentation. Treatment includes complete SIP removal by endoscopic approach with histological examination. Follow-up of these patients is critical to diagnosing relapse, which can be either early or late. It is important to diagnose recurrence to enable early treatment, especially in case of associated carcinoma or malignancy. In case of SCC, additional radiotherapy and/or neoadjuvant chemotherapy is needed, because it shows promising results in improving outcomes. In this article, we present a clinical case of managing a patient with malignancy of inverted papilloma, which led to extensive destruction.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Immunotherapy in the treatment of chronic polypous rhinosinusitis with comorbid bronchial asthma].","authors":"E V Bezrukova, S A Artyushkin, E A Varyushina, A S Simbirtsev","doi":"10.17116/otorino20259001129","DOIUrl":"10.17116/otorino20259001129","url":null,"abstract":"<p><p>The leading factors in the pathogenesis of chronic polyposis rhinosinusitis (CRSwNP) are dysfunction of the epithelial barrier of the nasal and sinus mucosa and dysregulation of the immune system, both at the systemic and local levels. A Th2-mediated immune response plays a central role in the development of disease in patients with CRSwNP CRPS, and CRSwNP is often associated with bronchial asthma (BA). At the present time, for the conservative treatment of patients with CRSwNP+BA, preference is given to drug therapy aimed at the correction of mucosal immunity. The use of interferon α2β (IFN α2β) and the dipeptide γ-D-glutamyl-L-tryptophan may reduce the severity of the long-term local inflammatory process. However, the clinical efficacy of these drugs in the context of chronic polyposis has not been studied. The aim of this study was to compare the efficacy of topical application of recombinant IFN α2β, recombinant IFN α2β in combination with γ-D-glutamyl-L-tryptophan and IL-4Rα receptor inhibitor in the treatment of patients with CRSwNP+BA. The patients were divided into three groups. In the first group (31 people), 1 million units of interferon alpha2b were injected into the polyposis tissue for five days. In the second group (31 people), interferon alpha2b at a dose of 1 million units and gamma-D-glutamyl-L-tryptophan at a dose of 0.1 mg were injected into the polypous tissue for five days. To assess the dynamics of clinical symptoms in the reference group (31 people), a drug with a known mechanism of action and efficacy - a genetically engineered IL-4Rα receptor inhibitor - was used. This drug was used 300 mg once every 2 weeks subcutaneously for 1 year. The obtained results showed that recombinant IFN α2β in combination with γ-D-glutamyl-L-tryptophan are pathogenetically appropriate preparations for conservative treatment of patients with the following initial indicators: severity of the polyposis process - 2.2+0.2 points, swelling - 2.8+0.4 points, and amount of discharge - 2.9+0.3 points. A single 5-day course of the above-mentioned preparations had a positive therapeutic effect, which was accompanied by a pronounced reduction in the clinical symptoms of the disease: the volume of polyposis tissue, nasal breathing difficulties and swelling of the nasal mucosa after one month and was maintained for one year. At the same time, the results of our study indicate the necessity of a longer period of application of recombinant IFN α2β in combination with γ-D-glutamyl-L-tryptophan in patients with CRSwNP+BA. The data obtained were comparable to the corresponding indicators when using the IL-4Ra inhibitor. In our opinion, the mechanism of action of the preparations is associated with a decrease in the activity of inflammatory and proliferative processes in the nasal and sinus mucosa.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Plastic perforation of the nasal septum with a flap on the branches of the superior labial artery].","authors":"Yu Yu Rusetsky, V A Stepanova, J T Mokoyan, V M Svistushkin, A N Yelumeeva, A N Shcheglov","doi":"10.17116/otorino20259002126","DOIUrl":"https://doi.org/10.17116/otorino20259002126","url":null,"abstract":"<p><p>An innovative method of endonasal closure of postoperative perforations of the nasal septum is presented, which is based on the use of a mucoperiosteal flap formed on the branches of the superior labial artery. Since 2023, the described technique has been used in 15 patients (average age 43 years). The duration of postoperative follow-up varies from 4 to 9 months. The assessment of the quality of life of patients before and after surgery was carried out using the SNOT-22 questionnaire. The average duration of the operation was 60 minutes. In 14 (93.3%) of the 15 patients, complete anatomical closure of the perforation was achieved. Complete healing of the donor area was noted 1 month after the operation. There were no postoperative complications (bleeding, infections). The average score for SNOT-22 decreased from 42.3±1.65 to 12.02±2.30 points 3-6 months after surgery (<i>p</i><0.05), indicating a significant improvement in the quality of life of patients. The high efficiency of the proposed method is demonstrated. The technical accessibility and prospects for wide application in surgical practice are noted. Further studies in large groups of patients are needed to definitively determine the place of this method in surgery for closing nasal septum perforations.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"26-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Nasolabial cyst: a systematic review of the literature].","authors":"I B Angotoeva, D S Pshennikov, L V Lyaskanova","doi":"10.17116/otorino20259002163","DOIUrl":"https://doi.org/10.17116/otorino20259002163","url":null,"abstract":"<p><p>We have conducted a systematic review of foreign and domestic literature covering data on nasolabial cysts. Nasolabial cyst is a benign non-ontogenic, often unilateral and left-sided, formation located in the nasolabial fold and vestibule of the nasal cavity, occurring mainly in women aged 30-50 years. Nasolabial cysts often remain undiagnosed, so the frequency of their detection is very low. Their origin is still a matter of debate; for more accurate data, it is necessary to conduct a thorough histological examination of each cyst using immunohistochemical analysis. Ultrasound can be used for the screening method of diagnosis of nasolabial cysts. Computed tomography of the nose and paranasal sinuses has a number of diagnostic advantages. The choice of surgical treatment depends on the size, location, infection of the nasolabial cyst, the surgeon's experience and the possibilities of conducting anesthesia.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Etiopathogenesis and therapeutic tactics of hemorrhages in the vocal fold in persons of voice-speech professions].","authors":"A I Kryukov, S G Romanenko, O G Pavlikhin, D I Kurbanova, E V Lesogorova, E N Krasilnikova, O V Eliseev","doi":"10.17116/otorino20259002114","DOIUrl":"https://doi.org/10.17116/otorino20259002114","url":null,"abstract":"<p><strong>Objective: </strong>To increase the effectiveness of treatment of patients with vocal fold hemorrhage based on the analysis of the disease etiology.</p><p><strong>Material and methods: </strong>In order to improve the treatment efficiency of vocal fold hemorrhage in people with voice and speech professions, 112 patients (35 men and 77 women) with vocal fold hemorrhage were examined and treated. Age from 24 to 58 years. Research methods: questionnaires, microlaryngoscopy, videolaryngostroboscopy, acoustic voice analysis (Kay Pentax system).</p><p><strong>Results: </strong>All patients complained of hoarseness. A change in voice that appeared during vocal exertion using a harsh sound attack was noted by 47 (42%) patients, while screaming - 13 (11%), during coughing on the background of acute respiratory viral infection and exacerbation of chronic destructive lung disease - 27 (24%), after fibrolaryngobronchoscopy - 3 (2%), after esophagogastroduodenoscopy - 1, after external neck injury in everyday life - 2 (1%), during the usual volume and intensity of vocal load - 19 (17%). Microlaryngoscopy revealed hemorrhage in the vocal fold in all patients, with 85 (76%) patients experiencing hemorrhage for the first time, 17 (15%) - repeatedly, for 10 (9%) - for the third time or more. A unilateral process was noted in 81 (72%) patients, a bilateral process in 31 (28%). Comprehensive treatment is prescribed to all patients based on an individual approach. The subjective voice score on the visual analog scale averaged 6.4±1.7 points, 1 month after the start of treatment - 9.4±0.4 points. The recovery time was also determined individually, depending on the patient's profession and the requirements for voice quality.</p><p><strong>Conclusions: </strong>1. Vocal fold hemorrhage is caused by a disruption of the vascular wall integrity due to a sharp increase in subglottic pressure. 2. Predisposing factors for the development of vocal fold hemorrhage are dystrophic changes in the mucous membrane of the vocal folds and concomitant pathology that contribute to increased vascular permeability. 3. No correlation was found between the volume of vocal fold hemorrhage, its prevalence, and the time of its reduction and restoration of voice function. 4. The duration of treatment is determined individually and depends on the dynamics of the videolaryngostroboscopic picture and the indicators of acoustic voice analysis and the patient's requirements for voice quality. 5. In case of recurrent hemorrhages, examination of the patient is indicated to exclude coagulopathy; in the presence of concomitant pathology accompanied by microangiopathy (diabetes mellitus, chronic glomerulonephritis, dyshormonal disorders in women, etc.), consultation with specialists is necessary to assess the activity of the concomitant disease, the degree of its impact on the microcirculatory bed and, according to indications, correction of its therapy.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Rehabilitation of preterm school-aged children with speech and hearing problems: a solution requiring a reasoned approach].","authors":"I V Savenko, E S Garbaruk, M Yu Boboshko","doi":"10.17116/otorino20259002141","DOIUrl":"https://doi.org/10.17116/otorino20259002141","url":null,"abstract":"<p><p>Common problems accompanying the development of preterm children include difficulties in speech perception and language use, which can lead to cognitive, communicative, social, and academic difficulties in school age. On the other hand, preterm children are at high risk for developing auditory impairments, which can affect not only the peripheral but also the central auditory system. Any level of auditory lesion, either isolated or in combination, can contribute to the development of central auditory processing disorders (APD). The article discusses the etiopathogenetic link between speech and hearing difficulties and dyslexia with APD. Based on the contemporary concept of the problem, an interdisciplinary approach to the diagnostic process is presented, which allows for identifying the nature and degree of speech and hearing disorders, and subsequently verifying the specific auditory deficit. The results of the diagnostic search enable the optimal (re)habilitation intervention, with a focus on auditory training. Depending on the identified disorders, either a peripheral «bottom-up» approach with correction of acoustic input and/or impaired central auditory functions is used, or a cognitive «top-down» approach aimed at improving higher mental processes, or a combination of both. When choosing the scope of (re)habilitation measures, the age and capabilities of the preterm child are taken into account.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 2","pages":"41-50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[On the issue of classification of vomer deformities in children].","authors":"A S Yunusov, E N Kotova","doi":"10.17116/otorino20259001135","DOIUrl":"10.17116/otorino20259001135","url":null,"abstract":"<p><p>Numerous publications on the classification of the nasal septum deformity (deviation) are mainly related to the anterior septal parts and the development of this pathology in the adult population. None of the available classifications contain the detail of the vomer deformities, required to select an algorithm for subsequent doctor's actions, as well as considering the clinical and anatomical features of this zone in children with congenital choanal atresia (CCA) or in its isolated deformity.</p><p><strong>Objective: </strong>To develop the classification of the vomer's deformities variants based on an analysis of CT of the paranasal sinuses (PNSs) in children with CCA and isolated deformity of the vomer, determining the choice of tactical and technical surgical treatment options.</p><p><strong>Material and methods: </strong>The classification is based on analysis of computed tomography of the PNSs of 334 children with CCA and isolated vomer deformity.</p><p><strong>Results: </strong>The vomer displacement towards the injured side was observed in the unilateral form of choanal atresia, thus arcuate, angular and lateral vomer displacement was revealed in the coronal plane. The following variants of the vomer deformity have been identified in the assessment of axial plane: S-shaped displacement towards the atresia when unilateral or towards one of sides, angular displacement by the type of crista, uniform displacement towards atresia, hyperplasia of the vomer's posterior edge, splitting of the vomer. The proposed classification systematizes numerous variants of the vomer's deformities, defined in the axial and coronal planes.</p><p><strong>Conclusion: </strong>The classification is the basis of the algorithm for selecting technical options and methods of surgical treatment of patients with CCA, choanal stenosis and isolated vomer deformity.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 1","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}