Mahmoud Ahmed Shawky, Amira Ahmed Shawky, Nada Zakaria Zakaria
{"title":"[Role of platelet-rich plasma in management of sensorineural hearing loss diseases].","authors":"Mahmoud Ahmed Shawky, Amira Ahmed Shawky, Nada Zakaria Zakaria","doi":"10.17116/otorino2026910114","DOIUrl":"10.17116/otorino2026910114","url":null,"abstract":"<p><p>Sensorineural deafness is a form of loss of hearing. It happens from damage to the cochlea. Platelet-rich plasma (PRP) is an autologous management derived from a case's blood and was observed to have pro-nerve regenerative characteristics. Intratympanic injection of PRP improves the cells of the hair of the inner ear, therefore enhancing the hearing.</p><p><strong>Objective: </strong>To show the effectiveness and safety of PRP in the management of sensorineural hearing loss (SNHL) diseases.</p><p><strong>Material and methods: </strong>150 patients who had sensorineural hearing loss because of different otological diseases, such as acoustic trauma, presbycusis, idiopathic sudden SNHL, in addition to Meniere's disease (MD). All cases received 4 times of intratympanic injections of PRP with one-week intervals between them.</p><p><strong>Results: </strong>In our research, 150 cases with SNHL diseases, as acoustic trauma, MD, presbycusis, and idiopathic sudden sensorineural hearing loss (ISSNHL) (68 (46.3%) males and 82 (54.6%) females) with age ranges from 18 to 78 years, received intratympanic injections of PRP. 50 patients with ISSNHL: 39 of them showed hearing improvement, with an average of 28 dB in pure tone audiometry (PTA) and 26% in speech discrimination. In acoustic trauma, 18 patients, 12 of them, showed hearing improvement, averaging 30 dB in PTA and 28% in speech discrimination. In presbycusis, 58 patients, 42 of them, showed an improvement in hearing of an average of 25 dB and 24% in speech discrimination. In Meniere's disease, 24 patients, 16 of them, showed an improvement in hearing of an average of 15 dB and 5% in speech discrimination.</p><p><strong>Conclusion: </strong>Platelet-rich plasma appears effective and safe for the management of sensorineural hearing loss with no systemic side effects as an oral steroid and at low cost.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A L Kozhanov, L G Kozhanov, V G Shatalov, A V Golovyakhina
{"title":"[Endolaryngeal microsurgical CO2 laser resection of the larynx and laryngopharynx for locally advanced schwannoma].","authors":"A L Kozhanov, L G Kozhanov, V G Shatalov, A V Golovyakhina","doi":"10.17116/otorino20269101193","DOIUrl":"10.17116/otorino20269101193","url":null,"abstract":"<p><p>A rare clinical case of locally advanced schwannoma of the larynx and laryngopharynx is described. Endolaryngeal resection with a CO<sub>2</sub> laser was performed, the tumor was removed, and organ function was restored.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"93-96"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I V Koroleva, A N Kornev, V A Lukyanenkova, G Sh Tufatulin, E S Shcheglova, E K Mefodovskaya, I A Grigoryeva
{"title":"[Features of the pronunciation in school-age children with minimal hearing impairment].","authors":"I V Koroleva, A N Kornev, V A Lukyanenkova, G Sh Tufatulin, E S Shcheglova, E K Mefodovskaya, I A Grigoryeva","doi":"10.17116/otorino20269101122","DOIUrl":"10.17116/otorino20269101122","url":null,"abstract":"<p><p>The peculiarities of the pronunciation of children aged 7-9 years with minimal hearing impairment (MHI) were studied. In 20 children with MHI and 20 children with normal hearing and speech development, pronunciation, the phonemic skills, articulatory praxis, as potential mechanisms of pronunciation disorders were assessed with a battery of tests. It was found that children with MHI are a heterogeneous group in terms of the state of pronunciation and the mechanisms that cause pronunciation disorders. 30% of children with MHI, mainly with unilateral hearing loss, did not have pronunciation disorders. In 70% of children with MHI the pronunciation disorders and manifestations of primary speech impairments, corresponding to the diagnosis F80.0 specific articulation disorder (articulatory dyspraxia) were detected. The majority of examined children with MHI showed difficulties in categorical differentiation of speech sounds, especially in the high-frequency range, and insufficient phonemic analysis. Obviously the pronunciation disorders in children with MHI are caused by both sensory (deficit of phonemic perception of high-frequency speech sounds) and motor (immaturity of articulatory praxis) mechanisms. These deficiencies, which are also risk factors for writing disorders in schoolchildren, should be taken into account when organizing speech therapy with children with MHI, as well as when deciding on the need for hearing aids for some children.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"22-28"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D I Kurbanova, A V Gurov, S G Romanenko, O G Pavlikhin, E V Lesogorova, E N Krasilnikova, V A Zemlyanov, O V Eliseev, E A Teplykh, E A Safyannikova
{"title":"[Features of the laryngeal mucosa microbiota in patients with chronic hyperplastic laryngitis (literature review)].","authors":"D I Kurbanova, A V Gurov, S G Romanenko, O G Pavlikhin, E V Lesogorova, E N Krasilnikova, V A Zemlyanov, O V Eliseev, E A Teplykh, E A Safyannikova","doi":"10.17116/otorino20269101164","DOIUrl":"10.17116/otorino20269101164","url":null,"abstract":"<p><p>The literature review analyzed the data concerning studies of the microbiome of the laryngeal mucosa in patients with chronic hyperplastic laryngitis. It remains a matter of discussion whether the inflammatory process in the larynx is primary with subsequent dysbiosis and excessive growth of pathogenic microorganisms, or whether changes in the structure of the normal microbial landscape become an inducer of the disease. The article reflects the results of basic research on the role of bacterial, fungal, and viral pathogens detected on the mucous membrane of the larynx in patients with chronic hyperplastic laryngitis, conducted by Russian and foreign scientists using various technological approaches.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"64-69"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Sh Tufatulin, S I Khairulina, M V Kreisman, N R Kaloeva, V V Bakhshinyan, I V Koroleva, V V Dvoryanchikov, S A Artyushkin, G A Tavartkiladze
{"title":"[Elevated ABR thresholds in the presence of otoacoustic emissions: case series].","authors":"G Sh Tufatulin, S I Khairulina, M V Kreisman, N R Kaloeva, V V Bakhshinyan, I V Koroleva, V V Dvoryanchikov, S A Artyushkin, G A Tavartkiladze","doi":"10.17116/otorino20269101176","DOIUrl":"10.17116/otorino20269101176","url":null,"abstract":"<p><p>The article presents three clinical cases of an unusual audiological profile in children, not previously described in the literature. The cases are of interest due to the atypical symptomatology featuring preserved otoacoustic emissions (OAEs) concurrent with elevated thresholds of auditory brainstem responses (ABRs). Notably, wave V exhibited normal morphology and latency; in some instances, the ABR thresholds correlated with the behavioral thresholds. This clinical presentation cannot be classified as either conventional peripheral sensorineural hearing loss or an auditory neuropathy spectrum disorder. It is hypothesized that the morphological substrate of this condition is a lesion at the level of the inner hair cell or the synapse. The underlying pathogenesis is suggested to involve mild impairments in neural synchronization, which are sufficient to allow for the recording of ABRs with thresholds that, in some cases, correlate with behavioral responses.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"76-85"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Autoimmune hearing loss in giant cell arteritis: a clinical case].","authors":"I V Savenko, M Yu Boboshko, S V Bryzgalova","doi":"10.17116/otorino20269101186","DOIUrl":"10.17116/otorino20269101186","url":null,"abstract":"<p><p>Giant cell arteritis (GCA), also called as temporal arteritis, is a systemic vasculitis, primary affecting individuals over 50 years of age and mostly women. The disease can manifest with symptoms of systemic inflammatory response syndrome as well with symptoms of systemic vasculitis affecting mainly medium and large vessels, including branches of the carotid artery, first of all the ophthalmic and temporal. Pathogenetically, arterial damage in GCA is a combination of autoinflammatory and autoimmune processes, resulting in vascular wall remodeling with narrowing of the arterial lumen and subsequent ischemia in the affected organs and tissues. One of the uncommon symptoms of GCA, which in some cases may precede the onset of the disease, is cochleovestibular dysfunction, in particular sensorineural hearing loss, which might occur in 25-60% of GCA cases. The clinical case of untypical GCA was shown. The disease manifested after SARS-Cov-2 infection as the subacute rhinosinusitis and bilateral otitis media with effusion that finally resulted in profound mixed hearing loss. The clinical features of the disease looked like granulomatosis with polyangiitis, however, no increase in antinuclear and antineutrophil cytoplasmic antibody levels was detected. A specific clinical feature with unilateral vision loss after 12 months from the disease onset could help to verify it. Urgently corticosteroid therapy let us relieve both main symptoms and rhinosinusitis with bilateral otitis media with effusion that resulted in significant hearing improvement. It has been suggested that the combination of middle and inner ear lesions in this case could either be a consequence of the simultaneous development of GPA and GCA, or was the result of coincidence of a number of their pathogenesis links, specifically the activation of B cells, as well as excessive proliferation of monocytes/macrophages producing metalloproteinase-9.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"86-92"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A I Kryukov, A Yu Ivoilov, N A Mileshina, N S Danilevskaya, M M Polunin, O I Simonova, K L Meshcheryakov, V N Sokolova, N Yu Kashirskaya, R A Zinchenko, V V Barilyak
{"title":"[Hearing impairment in children with cystic fibrosis].","authors":"A I Kryukov, A Yu Ivoilov, N A Mileshina, N S Danilevskaya, M M Polunin, O I Simonova, K L Meshcheryakov, V N Sokolova, N Yu Kashirskaya, R A Zinchenko, V V Barilyak","doi":"10.17116/otorino20269101141","DOIUrl":"10.17116/otorino20269101141","url":null,"abstract":"<p><p>The process of hearing impairment in children suffering from cystic fibrosis remains one of the pressing problems for the scientific medical community today. The article examines the effect of systemic antibacterial therapy with aminoglycoside antibiotics on the auditory function of children with cystic fibrosis.</p><p><strong>Objective: </strong>To analyze the causes of hearing loss and the causes of hearing impairment in children with cystic fibrosis from antibacterial therapy with aminoglycoside antibiotics.</p><p><strong>Material and methods: </strong>Search for literature sources using the search engines PubMed, Web of Science and eLibrary.</p><p><strong>Results: </strong>A review of the literature shows that the acute problem of sensorineural hearing loss is associated with frequent use of aminoglycosides, and predictors of conductive hearing loss are inflammatory processes in the middle ear and eustachian tube. It has been demonstrated that not in all cases, antibacterial therapy with aminoglycoside antibiotics leads to hearing impairment, which demonstrates the urgent need to study the auditory function of children with cystic fibrosis and identify the characteristics of hearing impairment.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"41-49"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I V Rakhmanova, M M Polunin, A V Kuznetsova, A I Petukhova, V V Bykonya
{"title":"[Features of the correlation between the auditory analyzer and speech development in premature infants and young children at the present stage according to the data of literature].","authors":"I V Rakhmanova, M M Polunin, A V Kuznetsova, A I Petukhova, V V Bykonya","doi":"10.17116/otorino20269101150","DOIUrl":"10.17116/otorino20269101150","url":null,"abstract":"<p><p>The literature review presents an analysis of data on the state of the auditory analyzer and the level of speech development in premature infants and toddlers.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"50-54"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V I Popadyuk, D S Pshennikov, I V Kastyro, A V Timoshenko
{"title":"[Study of the dependence of the width of the piriform aperture on the size and shape of the external nose].","authors":"V I Popadyuk, D S Pshennikov, I V Kastyro, A V Timoshenko","doi":"10.17116/otorino20269101129","DOIUrl":"10.17116/otorino20269101129","url":null,"abstract":"<p><p>Currently, the parameters of the external nose and the width of the piriform aperture are known. However, there is no data on their relationship with each other.</p><p><strong>Objective: </strong>To identify the relationship between the size and shape of the external nose and the width of the piriform aperture.</p><p><strong>Materials and methods: </strong>In the course of the work on the basis of the Ryazan Regional Clinical Hospital named after N.A. Semashko, 106 people (45 men and 61 women from 18 to 65 years old) were examined for the period from 2022 to 2024, whose piriform aperture width was compared with the parameters of the external nose using correlation analysis methods. The relationship was determined using the Pearson and Spearman correlation coefficients.</p><p><strong>Results: </strong>The presence of a hump in all study groups has a statistically significant negative correlation with the width of the piriform aperture. The value of the nasal index in all study groups directly correlates with the width of the piriform aperture. The width of the external nose and the pyriform aperture are interrelated when measuring smaller noses, and the projection and length of the nose do not affect the size of the piriform aperture.</p><p><strong>Conclusions: </strong>Despite the fact that the studied correlation coefficients have a small value, which corresponds to a moderate or weak correlation strength, the obtained results can help to identify the narrowness of the pyriform aperture according to the shape and specified parameters of the external nose, which must be taken into account when planning operations on the piriform aperture.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T A Fominykh, S A Kutia, V S Ulanov, A V Myazina, D V Petrovsky
{"title":"[A brief history of mastoidectomy. Contribution of Jean-Louis Petit (1674-1750)].","authors":"T A Fominykh, S A Kutia, V S Ulanov, A V Myazina, D V Petrovsky","doi":"10.17116/otorino20269101197","DOIUrl":"10.17116/otorino20269101197","url":null,"abstract":"<p><p>The article is dedicated to the 350<sup>th</sup> anniversary of the birth and 275<sup>th</sup> anniversary of the death of the great French surgeon Jean-Louis Petit (1674-1750), who made an invaluable contribution to various branches of theoretical and practical medicine, including otolaryngology. Petit was the first who purposefully perform trepanation of the mastoid process in mastoiditis to drain mastoid cells filled with pus. It was described in his work \"Traité des maladies chirurgicales\", published posthumously in 1774. Subsequently, Hermann Schwartze (1837-1910) took into account J.-L. Petit's experience and improved the technique of mastoidectomy.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"91 1","pages":"97-100"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}