Vestnik otorinolaringologii最新文献

{"title":"[The results of a 5-year clinical and epidemiological study of the National Program \"Chronic tonsillitis\"].","authors":"S A Artyushkin, Yu K Yanov, S V Ryazantsyev, N V Eremina, V K Artyushkina, S A Eremin","doi":"10.17116/otorino20248906128","DOIUrl":"https://doi.org/10.17116/otorino20248906128","url":null,"abstract":"<p><strong>Objective: </strong>To study the epidemiological characteristics of chronic tonsillitis (ChT), the need for patients to undergo conservative and surgical treatment, and a comparative assessment of the effectiveness of conservative treatment of patients with chronic tonsillitis using Tonsilotren as monotherapy and in complex treatment. The study involved 999 otorhinolaryngologists from the outpatient network of 20 major Russian cities. The data of 74125 patients diagnosed with ChT were analyzed. A significant predominance of the compensated form of ChT has been established, among the types of decompensation - relapses of acute tonsillitis. The peculiarities of changes in the structure of ChT forms during the period of Sars-CoV-2 coronavirus infection have been established. The expediency of widespread implementation of active measures to identify patients with compensated form of ChT, to perform anti-relapse conservative treatment of ChT using the drug Tonsilotren based on criteria of its effectiveness (IMOS) and tolerability (IMPSS) has been proved.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 6","pages":"28-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparative analysis of different types of tampons used after septoplasty, conchotomy of the inferior turbinates].","authors":"A I Kryukov, P L Chumakov, A S Tovmasyan, V V Yanovsky, A E Kishinevskii, N V Shvedov, V V Mosin, A V Artemyeva-Karelova","doi":"10.17116/otorino20248905116","DOIUrl":"10.17116/otorino20248905116","url":null,"abstract":"&lt;p&gt;&lt;p&gt;In otorhinolaryngology, the question of improving the tactics of early postoperative management in patients who have undergone surgery on the structures of the nasal cavity remains open. The timing of rehabilitation, the possible outcome of postoperative inflammation of the mucous membrane and the patient's ability to work depend on the choice of tactics. The nasal cavity differs from other anatomical areas in its rich blood supply, and therefore the problem of adequate hemostasis in the early stages after undergoing surgical treatment is still extremely relevant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To study the methods of postoperative hemostasis and the degree of traumatization of the nasal mucosa when using various types of tamponade in patients who underwent septoplasty and sparing lower conchotomy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Material and methods: &lt;/strong&gt;We operated on and examined 40 patients. The patients were divided into four groups: in patients of group 1 (&lt;i&gt;n&lt;/i&gt;=10), the operation was completed with nasal cavity tamponade with gauze swabs; in patients of group 2 (&lt;i&gt;n&lt;/i&gt;=10), nasal cavity tamponade was performed with Merocel tampons (Medtronic Xomed, Inc., USA); in patients of group 3 (&lt;i&gt;n&lt;/i&gt;=10) tamponade was performed with elastic finger tampons; for patients of group 4 (&lt;i&gt;n&lt;/i&gt;=10) tamponade was performed with filling hydrotampons. In the postoperative period, the severity of pain during nasal tamponade was assessed using a visual analogue scale (VAS), the volume of nasal blood loss during tampon removal, depending on the type of tamponade, the presence/absence of recurrent nosebleeds in the early postoperative period. To objectively assess the severity of the inflammatory reaction of the nasal mucosa against the background of tamponade, a cytological examination of smear prints from the surface of the tampon was performed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The severity of pain was insignificant in patients of all four groups. The average VAS score in patients of group 1 (gauze tampons) was 0.94±0.16 points; group 2 (Merocel tampons) - 0.92±0.14 points; group 3 (elastic tampons) - 0.72±0.09 points; group 4 (filling hydrotampons) - 0.96±0.13 points (&lt;i&gt;p&lt;/i&gt;&lt;0.05). The volume of blood loss after evacuation of gauze tampons and Merocel tampons was 114.3±35.1 ml and 140.1±22.2 ml, respectively, which exceeded the volume of blood loss when removing elastic tampons (30.4±13.1 ml) and hydrotampons (23.1±11.0 ml) by more than 80%; patients with intranasal elastic tampons and original hydrotampons with internal gluings had no recurrence of bleeding in the early postoperative period, unlike patients with tamponade with gauze turunds and Merocel; according to the results of cytological examination, more pronounced destructive changes in the ciliated epithelium were noted when using gauze turunds and Merocel tampons.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;In the first 24 hours after surgery, regardless of the type of tampons used, there was consisten","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 5","pages":"16-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Balloon dilation as an alternative to tracheotomy for acquired subglottic stenosis in children of the first year of life].","authors":"Yu L Soldatskiy, D N Nikitina, M M Polunin, S R Edgem, N L Krugovskaya, A S Subbotina","doi":"10.17116/otorino20248901110","DOIUrl":"https://doi.org/10.17116/otorino20248901110","url":null,"abstract":"<p><strong>Objective: </strong>To study the efficacy and safety of balloon dilation as the first choice method in the treatment of children of the first year of life with acquired subglottic stenosis.</p><p><strong>Material and methods: </strong>A retrospective analysis of the treatment of 25 patients aged 27 days to 11 months of life (average age 5.3±3.76 months) with subglottic stenosis caused by prolonged intubation, in whom balloon dilation was the first method of treatment. Grade III Cotton-Myer stenosis was preoperatively detected in 22 children, the remaining 3 had grade II stenosis.</p><p><strong>Results: </strong>The success rate of balloon dilation was 100%; tracheotomy was not required in any case, the absence of stenosis during a follow-up examination in the catamnesis was recorded in 14 (56%) children, the remaining 11 (44%) had grade 0-I stenosis and did not cause respiratory disorders. In 1 child (1.5 years old), a subglottic cyst was removed after balloon dilation. One dilation was required in 18 (72%) children, two - in 5 (20%), three and four - respectively for 1 patient. If additional intervention was necessary, the operation was repeated 10 days - 3 months after the previous one. There were no postoperative complications.</p><p><strong>Conclusion: </strong>Balloon dilation is a highly effective and safe alternative to traditional surgical interventions for acquired subglottic stenosis in children of the first year of life and can be recommended as a method of first choice.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 1","pages":"10-15"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Characteristics of lipid peroxidation processes and factors of the antioxidant defense system in chronic rhinitis].","authors":"O V Smirnova, N S Goncharova","doi":"10.17116/otorino20248901116","DOIUrl":"https://doi.org/10.17116/otorino20248901116","url":null,"abstract":"<p><p>The problem of chronic rhinitis (CR) remains unresolved in the world, while it has a negative impact on the quality of life of patients. Chronic forms of rhinitis suffer from 10-20% of the population, and its symptoms in epidemiological studies are noted in 40% of respondents. One of the leading mechanisms of disease occurrence is oxidative stress.</p><p><strong>Objective: </strong>To study the state of the processes of lipid peroxidation and antioxidant protection in various types of chronic rhinitis.</p><p><strong>Material and methods: </strong>The study included 50 patients with CR, of which 21 were with chronic allergic rhinitis (CALR), 20 with chronic vasomotor rhinitis (CVR), 9 with chronic atrophic rhinitis (CAR). The control group was represented by 50 practically healthy volunteers with no otorhinolaryngological complaints. The indicators of the LPO-AOD system in erythrocytes were evaluated by spectrophotometric methods. Statistical data processing was carried out using the Statistica 7.0 software package (StatSoft, USA).</p><p><strong>Results: </strong>In all patients with CR in the blood erythrocytes, an increase in the level of malondialdehyde (MDA), a decrease in the activity of superoxide dismutase (SOD), catalase (CAT) relative to the control group was found. With CAR, the most pronounced changes are determined, with CVR - minimal. In patients with CR, lipid peroxidation is activated, MDA increases by 1.29 times, by 1.37 times with CAR, and by 1.31 times with CALR relative to normal values. The activity of the antioxidant system decreases, which reflects the classical variant of inhibition of antioxidant enzymes: SOD is reduced by 1.08 times in CAR, by 1.07 times in CALR, and 1.04 times in CVR, CAT in CAR is reduced by 1.02 times; CALR by 1.02 times, with CVR by 1.01 times. The coefficient of oxidative stress with CVR is 1.36, with CAR is 1.5, with CALR is 1.42.</p><p><strong>Conclusion: </strong>In CR, the predominance of pro-oxidant processes over antioxidant ones is revealed, a slight oxidative stress is detected, probably due to the presence of hypoxia and intoxication syndrome. An in-depth study of lipid peroxidation processes and factors of the antioxidant defense system, depending on the CR phenotype, can be used to correct therapy and prevent exacerbations, as well as markers of progression and prognosis of chronic rhinitis.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 1","pages":"16-20"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical case of tuberculous otitis media in early childhood].","authors":"A Yu Ivoylov, M M Polunin, N A Mileshina, S S Osipenkov, A N Radtsig","doi":"10.17116/otorino20248901132","DOIUrl":"https://doi.org/10.17116/otorino20248901132","url":null,"abstract":"<p><p>Nowadays, the incidence of tuberculosis remains high all over the world, despite the vaccination, medical support, social policy. The main reasons for this are the high level of migration, the prevalence of bad habits, the prevalence of immunodeficiency conditions, the formation of resistance to antimicrobial drugs, the tendency to refuse vaccination. At the same time, great difficulties arise in the diagnosis of extrapulmonary forms of infection. The purpose of this publication is to remind about the peculiarities of the course and diagnosis of tuberculous otitis media. According to the literature, the main characteristic features of tuberculous of the middle ear are prolonged suppuration without pronounced pain syndrome, inefficiency of standard antibacterial therapy, the anamnestic data about contacts or violation of the vaccination schedule, multiple perforations and a pronounced granulation process during otoscopy, a pronounced destructive process in the temporal bone during X-ray examination. The article presents a clinical case of the development of tuberculous otitis media in a young child with delayed diagnostics and the development of mastoiditis with required emergency surgical treatment. Verification of the etiology of the disease and the specific treatment carried out made it possible to achieve complete relief of ear symptoms, restoration of the tympanic membrane and ventilation of the middle ear.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 1","pages":"32-36"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Compression elastography as a new method of ultrasound imaging in the differential diagnosis of chronic tonsillitis].","authors":"N A Daikhes, A I Kryukov, I A Kim, E V Nosulya, E A Zubareva, D V Trukhin, I V Rychkova, T V Sukhostavtseva, A S Tovmasyan","doi":"10.17116/otorino20248904120","DOIUrl":"https://doi.org/10.17116/otorino20248904120","url":null,"abstract":"<p><p>Chronic tonsillitis remains as an urgent problem in modern otorhinolaryngological practice, which requires improving the diagnostic methods of this pathology.</p><p><strong>Objective: </strong>To increase the diagnostic information content of objective methods for differential diagnosis of different forms of chronic tonsillitis.</p><p><strong>Material and methods: </strong>The study involved 97 patients who were divided into two groups: the 1st group (39 patients) - with a simple form; the 2nd group (58 patients) - with a toxic-allergic form of chronic tonsillitis. To assess the structure of the palatine tonsils, patients underwent ultrasound in the compression elastography mode.</p><p><strong>Results: </strong>According to results, patient with simple form of chronic tonsillitis in 64.1±7.68% cases had rigid structure of palatine tonsils, while toxic-allergic form is characterized by an elastic structure of the tonsils (58.62±6.47%).</p><p><strong>Conclusion: </strong>The ultrasound compression elastography helps to value efficiently the pathology of the palatine tonsils and conduct a differential diagnosis of clinical forms of chronic tonsillitis.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 4","pages":"20-25"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Peak nasal inspiratory flow in the assessment of nasal airway obstruction].","authors":"S V Krasilnikova, A S Kolesnik, K V Gorbunova, T I Eliseeva, A V Shakhov","doi":"10.17116/otorino20248904147","DOIUrl":"https://doi.org/10.17116/otorino20248904147","url":null,"abstract":"<p><strong>Relevance: </strong>Nasal congestion is one of the most common complaints in otolaryngology practice and can significantly impact the quality of life for patients. Objective and subjective assessments provide different information, but objective assessment of nasal obstruction is crucial for accurate diagnosis and appropriate treatment. This review demonstrates that peak nasal inspiratory flow (PNIF) is a reproducible and reliable measure of objective nasal patency. It is inexpensive, easy to use, suitable for serial measurements, and can be applied to patients of different age groups. PNIF is recommended for use in every outpatient clinic that treats patients with nasal congestion.</p><p><strong>Objective: </strong>To summarize the data on the application of PNIF in diagnosing conditions of the nasal airways.</p><p><strong>Material and methods: </strong>Publications (articles and relevant abstracts) available in the PubMed and eLibrary databases were analyzed.</p><p><strong>Conclusion: </strong>PNIF offers an objective and non-invasive assessment of nasal airflow, aiding in diagnosis, therapy monitoring, and preoperative planning. Further research, standardization, and establishment of normative data will enhance the informative value of peak nasal inspiratory flow in assessing nasal obstruction.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 4","pages":"47-53"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Sinonasal hemangiomas: principles of diagnosis and treatment. Literature review].","authors":"A S Tovmasyan, K E Klimenko, E I Zelikovich, A G Kurilenkova, E V Filina, A E Kishinevskii, S R Ramazanov","doi":"10.17116/otorino20248904154","DOIUrl":"https://doi.org/10.17116/otorino20248904154","url":null,"abstract":"<p><p>Hemangiomas of the nasal cavity are extremely rare in the practice of an otorhinolaryngologist and can be presented in various histopathological variants. Scientific data on hemangiomas of the sinonasal region are analyzed and systematized. The article describes the principles of diagnosis and choice of the method of surgical treatment of hemangiomas. An analysis of the literature data shows that with hemangiomas of the nasal cavity, a comprehensive examination of the patient is required, including collection of complaints and anamnesis, endoscopy of the nasal cavity and computed tomography of the paranasal sinuses, and with significant hemangiomas spreading to neighboring anatomical areas, magnetic resonance imaging with intravenous contrast.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 4","pages":"54-59"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cochleovestibular manifestations in coronavirus infection].","authors":"N L Kunelskaya, Ya Yu Nikitkina, Z O Zaoeva, E V Baibakova, E S Yanyushkina, M A Chugunova, Yu V Levina, E A Manaenkova, S D Revazishvili","doi":"10.17116/otorino20248903118","DOIUrl":"https://doi.org/10.17116/otorino20248903118","url":null,"abstract":"<p><p>One of the main causes of the of the inner ear pathology is a viral infection including SARS-CoV-2 virus. On the other hand the psycho-emotional state of patients also affects patients with hearing loss, tinnitus and dizziness, and an increase in depression and anxiety was revealed during the period of self-isolation. Goal of our study was to analyze cochleovestibular pathology in patients with COVID-19. The study involved 84 patients and the leading complaint was hearing loss - in 70 patients, tinnitus - in 54 patients, dizziness - in 50 patients. In addition, an increased anxiety background was found in patients, as well as signs of depression. Thus, the 2020 pandemic period was a high risk period for patients with inner ear pathology, which may be associated not only with the actual pathological effect of the virus on the auditory and vestibular system, but also with changes in the psycho-emotional status of patients.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 3","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Modern pharmacotherapy of acute bacterial sinusitis: results of an open randomized clinical trial of the therapeutic equivalence of Cefixime EXPRESS and Suprax Solutab].","authors":"A I Kryukov, A V Gurov, G B Shadrin, G N Izotova, M A Yushkina, A V Muzhichkova, P K Zotova","doi":"10.17116/otorino20248903148","DOIUrl":"10.17116/otorino20248903148","url":null,"abstract":"<p><strong>Background: </strong>Acute bacterial sinusitis is one of the most common causes of prescribing systemic antibacterial drugs in otorhinolaryngology. With bacterial etiology of the disease, beta-lactam antibiotics are prescribed, in particular cefixim. Cefixim in the form of dispersible tablets has high clinical and bacteriological efficiency, as well as good tolerability in patients with acute sinusitis.</p><p><strong>Objective: </strong>To study the therapeutic equivalence of two drugs of cefixim (reproduced drug Cefixim Express and reference drug Suprax Solutab) in patients with acute bacterial sinusitis.</p><p><strong>Material and methods: </strong>60 adult patients with a diagnosis of acute bacterial sinusitis took part in a randomized open comparative clinical study. Patients of group 1 (<i>n</i>=30) received the drug Cefixim Express in the form of dispersible tablets 400 mg once a day. Group 2 (<i>n</i>=30) received Suprax Solutab in the form of dispersible tablets 400 mg once a day. The duration of treatment course was 7 days. All patients conducted general clinical and otorhinolaryngological examinations, assessment of symptoms of acute sinusitis, assessment of the general clinical impression of the therapy, tolerance of treatment, analysis of the frequency of unwanted phenomena before treatment, 3 days after the beginning of therapy and after the course completion (7 days).</p><p><strong>Results: </strong>Recovery occurred in 63.3% of patients in group 1 according to the inspection on the 7^th day of treatment and in 66.67% of patients in group 2. The rate of clinical symptoms regression by the end of therapy was comparable in the comparison groups. Hyperemia of the nasal mucosa, purulent nasal discharge and difficulty in nasal breathing (<i>p</i><0.01) regressed by the 7^th day in patients of both treatment groups. The incidence of adverse reactions on the 7^th day of treatment in group 1 was 10%, in group 2 - 6.7% (<i>p</i>>0.05).</p><p><strong>Conclusion: </strong>The drug Cefixim Express has high therapeutic effectiveness in the treatment of acute bacterial sinusitis, comparable to Suprax Solutab. Cefixime EXPRESS has demonstrated a good tolerability and a favorable safety profile.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 3","pages":"48-56"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}