Vestnik otorinolaringologii最新文献

{"title":"[Epidemiological features of laryngeal papillomatosis in adults in Moscow].","authors":"A I Kryukov, S G Romanenko, A B Oteyami, N H Amegan, O G Pavlikhin, O V Eliseev, D I Kurbanova, E V Lesogorova","doi":"10.17116/otorino2024890314","DOIUrl":"https://doi.org/10.17116/otorino2024890314","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the incidence of laryngeal papillomatosis (LP) and LP recurrence in adults and to determine the risk factors for the development of LP recurrence in adults in Moscow. To solve the tasks set, a survey of patients carried out, including the collection of complaints and anamnesis, a standard examination of the ENT organs, an assessment of the condition of the larynx, and a histological examination.</p><p><strong>Material and methods: </strong>We conducted a retrospective analysis of the case histories of 299 patients with LP observed and treated at the Sverzhevsky Research and Clinical Institute of Otorhinolaryngology in the period 2010-2020.</p><p><strong>Results: </strong>On average, over the entire study period, the prevalence of PG was 17.80%. It was found that out of 299 patients, 69.6% (<i>n</i>=208) had a relapse of LP. Papilloma of the larynx were more often localized in the glottis. 275 (92%) patients had a widespread form of LP. LP recurrences were significantly more common in women and in patients with an existing cicatricle process in the larynx. The relapse rate was higher in non-smokers (73.5% vs 47.8%; <i>p</i><0.001). Although the recurrence rate was higher in patients with non-voice occupations (70.6% vs. 52.9%), there was no statistically significant association between relapses and the vocal professions (<i>p</i>=0.125).</p><p><strong>Conclusion: </strong>As a result of the study, a number of risk factors for laryngeal papillomatosis recurrent have been identified, and their study should be continued.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 3","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A comparative study of the effectiveness of azoximer bromide and surgery on the quality of the life of patients with chronic rhinosinusitis without nasal polyps].","authors":"V M Svistushkin, G N Nikiforova, A S Dekhanov, A N Nikiforova","doi":"10.17116/otorino20248902146","DOIUrl":"10.17116/otorino20248902146","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to compare the effects of azoximer bromide and surgery on the quality of life of patients with chronic rhinosinusitis (CRS) without polyps. We also wanted to examine changes in the patient's emotional state and the nature of their complaints.</p><p><strong>Material and methods: </strong>The results of using the Visual Analogue Scale (VAS) and the Sino-Nasal Outcome Test-22 (SNOT-22) questionnaire in patients with CRS without severe or moderate-severe polyps, before treatment and 3 months after treatment, are presented. Patients, depending on their choice, were treated with functional endoscopic intervention or a course of 6 mg/ml azoximer bromide (1 ml per day, a course of at least 10 days).</p><p><strong>Results: </strong>The median [interquartile range] score for VAS in patients before azoximer bromide treatment was 6.7 [6.3; 7.05] points, after treatment 4.2 [3.50; 4.70] points. The median [interquartile range] of VAS scores in patients before surgical treatment was 6.4 [6.1; 6.9] points, and after 4.8 [4.50; 5.30] points. The median [interquartile range] of the SNOT-22 score before azoximer bromide treatment was 33 [32; 36] points, after treatment - 24 [22; 25] points. The median [interquartile range] of the SNOT-22 score before surgery was 34 [32; 36] points, after treatment - 19 [18; 21.25] points.</p><p><strong>Conclusion: </strong>Azoximer bromide treatment and surgery improve the quality of life of patients with CRS (according to the visual analog scale and all SNOT-22 domains) during a control survey after 3 months (<i>p</i><0.001). Surgical treatment has a stronger impact on the quality of life, which is more noticeable in the influence on the domains \"Rhinological symptoms\", \"Extranasal symptoms\", \"Ear/facial symptoms\" (<i>p</i><0.05). According to the domains \"Psychological dysfunction\", \"Sleep dysfunction\", surgical intervention had no advantages in affecting the quality of life, compared with taking azoximer bromide (<i>p</i><0.05).</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 2","pages":"46-51"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The use of autologous platelet-rich plasma in the treatment of chronic pharyngitis].","authors":"E V Mirzabekyan, E I Rusanova, K P Ivanov","doi":"10.17116/otorino20248902152","DOIUrl":"10.17116/otorino20248902152","url":null,"abstract":"<p><p>The results of a prospective open cohort study of the use of platelet-rich plasma (platelet-rich plasma - PRP) in patients with chronic pharyngitis during the exacerbation of the disease are presented.</p><p><strong>Objective: </strong>To evaluate the clinical efficacy of autologous PRP in the treatment of chronic pharyngitis.</p><p><strong>Material and methods: </strong>Autologous PRP was injected into the posterior pharyngeal wall as a course of endopharyngeal blockages as part of the complex therapy of chronic pharyngitis. Patients in the control group received standard therapy, without the use of autologous PRP. The effectiveness of the studied technique was evaluated by statistical analysis of the intensity of symptoms of the disease, determined by patients throughout the entire period of treatment in the patient's diary, as well as by analyzing data from mass spectrometry of microbial markers and bacteriological examination of the pharyngeal mucosa, collected at the beginning of the study and 14 days after completion of the course of therapy.</p><p><strong>Conclusion: </strong>The use of a course of endopharyngeal blockades with autologous platelet-rich plasma as part of the complex therapy of chronic pharyngitis, according to our estimates, provides a significant effect in the form of higher rates of reduction in the severity of symptoms of the disease, a significant reduction in the number of microorganisms deviating from the reference values (by 2 times or more), a decrease in the duration of the disease compared with the control group.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 2","pages":"52-58"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A clinical case of successful treatment of an air cyst of the larynx].","authors":"L A Lazareva, Ts Z Baiduev, T M Nazarenko","doi":"10.17116/otorino202489021101","DOIUrl":"10.17116/otorino202489021101","url":null,"abstract":"<p><p>Laryngeal air cyst (laryngocele) is a rare disease that is an abnormal cystic expansion of the deep structures of the laryngeal ventricle. They can be accompanied by serious complaints, such as shortness of breath, difficulty breathing during exercise, as well as at rest with large cysts. Computed tomography is the most effective method for determining the type, localization and degree of laryngocele. Although surgical treatment is considered the method of choice in cases of laryngeal air cyst, the approach significantly depends on the size of the lesion.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 2","pages":"101-104"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of prolonged remission after discontinuation of biological therapy in a patient with severe uncontrolled chronic rhinosinusitis with nasal polyps].","authors":"M A Budkovaya, S V Ryazantsev, S A Rebrova","doi":"10.17116/otorino20248906199","DOIUrl":"https://doi.org/10.17116/otorino20248906199","url":null,"abstract":"<p><p>Currently, targeted biological therapy is an innovative and highly effective approach in the treatment of severe chronic rhinosinusitis with nasal polyps (CRSwNP) associated with T2 inflammation that is uncontrolled by standard treatment methods. The article presents the first experience of long-term observation of a patient who, one year after the start of targeted biological therapy with dupilumab, independently stopped the treatment due to complete relief of symptoms of CRSwNP, despite recommendations to continue therapy to maintain control. At the same time, one year after the refusal of biological therapy, the patient showed persistent clinical remission in relation to the symptoms of CRSwNP, confirmed by the results of videoendoscopic examination of the nasal cavity and computed tomography of the sinuses. The described clinical observation emphasizes the need to develop a personalized approach to prescribing immunobiological therapy in patients with CRSwNP and a more detailed study of the criteria for a super-response to this treatment.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 6","pages":"99-106"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ultrasonography for peritonsillar abscess diagnosis: benefits and drawbacks].","authors":"M V Subbotina, T D Prikhodko, A O Barakin, O M Butyrin, Yu D Puzrenkova, O S Bakhaeva","doi":"10.17116/otorino20248904181","DOIUrl":"10.17116/otorino20248904181","url":null,"abstract":"<p><p>In 2 clinical cases the neck soft tissues ultrasound in the young and old patients allowed to solve the main diagnostic tasks: to determine the presence of peritonsillar abscess cavities, their sizes and localization; to exclude the fit of large vessels near to abscesses and the presence of abnormal vessels; to conduct differential diagnosis of abscesses from a tumor and allergic angioedema. Ultrasound with external access did not require any special preparation, was easily tolerated by the patient, was informative, but it was difficult to determine the puncture place. Intraoral ultrasound was more difficult to conduct, because the transducer should be small in size to enter the patient's mouth. If the patient had a pronounced trismus, intraoral ultrasound couldn't be done. On the one hand in a case of children use the standard transducer cannot fit in the mouth as well and may be damaged by teeth. But on the other hand, the abscess puncture site can be more easily determined by intraoral examination. Compared to multi-slice computed tomography with contrast, the ultrasound method is cheaper, more accessible, faster, more informative and there is no radiation exposure associated with this method.</p><p><strong>Conclusion: </strong>Ultrasound of the peritonsillar region by external and intraoral methods is informative for detecting peritonsillar abscess, especially in difficult diagnostic cases.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 4","pages":"81-85"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of subglottic cysts in monochorionic monoamniotic twins].","authors":"D I Andrienko,&nbsp;S A Bulynko,&nbsp;K A Evgrafova,&nbsp;Yu L Soldatskiy,&nbsp;M A Amirbekov,&nbsp;Ya A Patrik","doi":"10.17116/otorino20228803190","DOIUrl":"https://doi.org/10.17116/otorino20228803190","url":null,"abstract":"<p><p>The first observation in the world literature of the development of subglottic cysts in the larynx in monochorionic monoamniotic twins is presented. The girls were born prematurely at 34 weeks of gestation, from the first day of life for 7 and 8 days, respectively, were transferred to mechanical ventilation. At the fourth month of life, symptoms of laryngeal stenosis appeared and began to gradually progress, conservative therapy had no effect. The diagnosis of subglottic cysts was established on the basis of fibrolaryngoscopy; after endolaryngeal surgery, breathing returned to normal. This case demonstrates the importance of timely endoscopic examination of the respiratory tract in children with stridor.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"88 3","pages":"90-93"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9878262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Combined method of treatment of synechiae of the nasal cavity].","authors":"A I Kryukov,&nbsp;T A Aleksanyan,&nbsp;A S Tovmasyan,&nbsp;I G Kolbanova,&nbsp;A E Kishinevskii,&nbsp;A A Arzumanyan,&nbsp;S R Ramazanov","doi":"10.17116/otorino20228803127","DOIUrl":"https://doi.org/10.17116/otorino20228803127","url":null,"abstract":"<p><p>Diseases of the nasal cavity and paranasal sinuses lead to the development of clinical symptoms, among which difficulty in nasal breathing is among the most common complaints of patients in the practice of otorhinolaryngologists. To prevent the development of synechiae of the nasal cavity in surgery, the following principles are defined: 1) to reduce tissue injury, which is achieved by using modern equipment (endoscopic, laser, radio frequency, etc.); 2) to create a barrier between nearby areas of the nasal mucosa by introducing various intranasal splints; 3) to improve the process of tissue regeneration with the help of medicines (regenerants, reparants, etc.). Currently, there is no single approach to the surgical treatment of synechiae of the nasal cavity. The high frequency of postoperative relapses indicates the need to develop effective methods for the prevention of synechiae of the nasal cavity. The choice of surgical tactics is usually carried out taking into account the localization and extent of synechiae of the nasal cavity. All known methods of surgical treatment, depending on the instruments used for excision of synechiae of the nasal cavity, can be conditionally divided into cold and hot. The Sverzhevsky Research Clinical Institute of Otorhinolaryngology has developed a method of complex treatment and prevention of synechiae of the nasal cavity using laser technologies, silicone splints and a hydrogel material based on sodium alginate with derinate.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"88 3","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9878266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Anatomical factors of temporal bone residual cholesteatoma: our experience].","authors":"V M Svistushkin,&nbsp;I T Mukhamedov,&nbsp;E G Varosyan,&nbsp;K V Eremeeva,&nbsp;Zh T Mokoyan","doi":"10.17116/otorino20228802180","DOIUrl":"https://doi.org/10.17116/otorino20228802180","url":null,"abstract":"<p><p>The article describes clinical cases of invasive cholesteatoma of the temporal bone pyramid, leading to a massive destruction of the surrounding structures. Paying attention to the importance of knowing the microsurgical anatomy of critical structures of temporal bone (the anterior bony plate (cog), the tensor tympani fold and the tendon, the tympanic orifice of the eustachian tube, the pretympanic recess, tympanic sinuses) bearing a significance and helping to improve the removal of the invasive cholesteatoma.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"88 2","pages":"80-85"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9828666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Morphological changes in the epithelium of the auditory tube with prolonged respiratory support in children of the first year of life].","authors":"I V Rakhmanova,&nbsp;E L Tumanova,&nbsp;A G Matroskin,&nbsp;N S Korchagina,&nbsp;R V Kotov,&nbsp;Yu S Ishanova","doi":"10.17116/otorino20228801117","DOIUrl":"https://doi.org/10.17116/otorino20228801117","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the condition of the epithelium of the cartilaginous part of the auditory tube in premature and full-term infants with prolonged respiratory support using noninvasive assisted ventilation (continuous positive airway pressure - CPAP) and artificial lung ventilation (ventilator).</p><p><strong>Material and methods: </strong>All the obtained material is distributed relative to the gestation period into the main and control groups. The main group (25 children) is represented by premature and full-term live-born children who were on respiratory support for a period of several hours to 2 months, the average gestation period of which was 30 weeks and 40 weeks, respectively. The control group (8 children) is represented by stillborn newborns with an average gestation period of 28 weeks. The study was conducted posthumously.</p><p><strong>Results: </strong>Prolonged use of respiratory support in premature and full-term children, regardless of the type (CPAP or ventilator), leads to a violation of the row of cilia of the ciliated epithelium, various inflammatory processes, as well as to the expansion of the ducts of the mucous glands of the epithelium of the auditory tube, which affects its drainage system.</p><p><strong>Conclusion: </strong>Prolonged respiratory support causes destructive changes in the epithelium of the auditory tube, which make it difficult to evacuate the mucous discharge from the tympanic cavity. This negatively affects the ventilation function of the auditory tube and in the future may lead to the development of chronic exudative otitis media.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"88 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10852659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}