Michael Apolinario, Christine Firth, Lana Matti, Marlene Girardo, Corbin Rayfield, Olubadewa Fatunde, David Liedl, Paul Wennberg, Fadi Elias Shamoun
{"title":"Warfarin and DOAC impact on cardiovascular and limb outcomes in patients with peripheral arterial disease.","authors":"Michael Apolinario, Christine Firth, Lana Matti, Marlene Girardo, Corbin Rayfield, Olubadewa Fatunde, David Liedl, Paul Wennberg, Fadi Elias Shamoun","doi":"10.1024/0301-1526/a001193","DOIUrl":"10.1024/0301-1526/a001193","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Peripheral arterial disease (PAD) increases cardiovascular (CV) morbidity and mortality, but remains underdiagnosed and undertreated. Several trials support low-dose direct oral anticoagulant (DOAC) use in PAD treatment, although this has yet to be widely adopted in clinical practice. <i>Patients and methods:</i> We conducted a retrospective study of patients who underwent ankle-brachial index testing (ABI) from 1996 - 2020 at Mayo Clinic. We included patients with PAD defined by abnormal ABI (<1.0 or >/=1.4). Primary outcomes evaluated were myocardial infarcts (MI), ischemic strokes (IS), critical limb ischemia (CLI)/amputation, bleeding events and all-cause mortality. DOAC and warfarin use were each compared to no anticoagulant use for the outcomes using univariate analysis and multivariate analysis. <i>Results:</i> 22,162 patients had abnormal ABI readings; 1,266 were on warfarin and 269 were on DOAC for any indication. Both the DOAC and warfarin groups showed significant a decrease in all-cause mortality. The DOAC group showed superior mortality outcomes with HR 0.50 [95% CI 0.40-0.63], p-value <0.001 compared to warfarin with HR 0.88 [95% CI 0.81-0.96], p-value <0.004. There appeared to be a similar trend for MI and CLI/amputation however this was not statistically significant. IS was similar with only warfarin being statistically significant. The DOAC group had improved bleeding outcomes compared to the warfarin group, HR 0.53 (95% CI 0.24-0.85), p-value 0.007. Notably, the addition of ASA for both AC groups resulted in significant HR >1. <i>Conclusions:</i> Our study shows that anticoagulation use, particularly DOACs, is associated with decreased all-cause mortality in patients with PAD. There appears to be a favorable trend for DOACs in MI, IS and CLI/amputation. Lastly, DOACs were found to have superior outcomes with bleeding events.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"273-279"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giacomo Buso, Jeanne Hersant, Sanjiv Keller, Igli Kalaja, Paola Bigolin, Enrica Porceddu, Francesca Ghirardini, Marko Novaković, Darren Galea Meilak, Andrej Džupina, Thomas Gary, Alessandra Bura-Rivière, Christian Heiss, Stefano Lanzi, Juraj Madaric, Vinko Boc, Muriel Sprynger, Tristan Mirault, Marianne Brodmann, Oliver Schlager, Lucia Mazzolai
{"title":"Cutting-edge European guidelines for managing lower extremity peripheral arterial disease - Featuring selected insights on PAD management.","authors":"Giacomo Buso, Jeanne Hersant, Sanjiv Keller, Igli Kalaja, Paola Bigolin, Enrica Porceddu, Francesca Ghirardini, Marko Novaković, Darren Galea Meilak, Andrej Džupina, Thomas Gary, Alessandra Bura-Rivière, Christian Heiss, Stefano Lanzi, Juraj Madaric, Vinko Boc, Muriel Sprynger, Tristan Mirault, Marianne Brodmann, Oliver Schlager, Lucia Mazzolai","doi":"10.1024/0301-1526/a001186","DOIUrl":"10.1024/0301-1526/a001186","url":null,"abstract":"<p><p><b></b> The new guidelines for the management of peripheral arterial and aortic diseases (PAAD) from the European Society of Cardiology and endorsed by the European Society of Vascular Medicine (ESVM), emphasize on a comprehensive and multidisciplinary approach focusing on prevention, diagnosis, treatment, and follow-up of patients with a wide range of PAAD, including lower extremity peripheral arterial disease (PAD). The aim of this summary, focusing on PAD and coordinated by the Young Academy of ESVM, is to provide young angiologists with the fundamental principles of these guidelines and to assist them in navigating their everyday clinical practice. PAD diagnosis relies on objective evaluation of flow/oxygen reduction at rest, with arterial ultrasound as the first imaging modality to confirm the presence of arterial lesions. The main goals of PAD management are not only to improve functioning and prevent the occurrence of adverse events at the lower limb level, but also to reduce the overall atherosclerotic burden and achieve the general well-being of patients. To this end, traditional and nontraditional cardiovascular risk factors need to be properly addressed through lifestyle changes and tailored drug therapies. For patients with exertional limb symptoms, supervised exercise training is recommended. Interventional treatment is indicated for limb salvage in patients with chronic limb threatening ischemia and may also be discussed in a multidisciplinary setting in less severe patients with persisting symptoms and reduced quality of life after a minimum period of optimal medical treatment including exercise therapy. For trainees or young specialists in Angiology/Vascular Medicine, these guidelines provide essential elements to improve patient management, encourage interdisciplinary collaboration, and ensure an integrated approach to vascular diseases.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"225-234"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early outcomes of the Third-generation of ClosureFast radiofrequency ablation for great saphenous vein reflux.","authors":"Domenico Baccellieri, Vincenzo Ardita, Nicola Galati, Claudia Anselmi, Benedetta Mangili, Roberto Chiesa","doi":"10.1024/0301-1526/a001195","DOIUrl":"10.1024/0301-1526/a001195","url":null,"abstract":"<p><p><b></b> <i>Background:</i> This study aimed to assess the safety of the third-generation ClosureFast catheter for radiofrequency ablation (RFA) in the treatment of great saphenous vein (GSV) reflux in patients presenting to a dedicated vein center. <i>Materials and methods:</i> All consecutive patients with incompetent GSV who underwent RFA between December 2023 and May 2024 were retrospectively analyzed. The primary study endpoints were technical success and postoperative complication rate at 30 days. Secondary study endpoints were freedom from GSV recanalization and recurrent varicose vein (RVV) rate over the follow-up. The improvement in symptoms (measured by the Venous Clinical Severity Score [VCSS]) was evaluated. <i>Results:</i> During the study period, 50 limbs were treated in 50 consecutive patients (mean age 55.8±13.4 years; 56% women; CEAP 2-4; VCSS >5). The technical success rate was achieved in 100% of cases. There was no significant incidence of 30-day complications. There were no instances of deep venous thrombosis or puncture site thermal injury. One patient (2%) had hyperpigmentation; two patients (4%) had ecchymosis; 4 patients (8%) had pain. At a mean follow-up of 2.9±1.4 months, GSV occlusion and freedom from reintervention rates were both 100% within 1 week and 30 days respectively. No patients had RVV over the follow-up. The VCSS score had decreased a median of 3.5 (IQR: 2.4-5) points from baseline (p<0.01). The mean CEAP class had decreased to 1.59 points from baseline, reflecting a shift towards milder disease categories (C0-C2). <i>Conclusions:</i> The third generation of RFA is safe and effective to ablate the GSV with a low complication rate in the perioperative period. However, durability over the follow-up and further studies with larger cohorts of patients are still needed to confirm these outcomes.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"280-286"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Predrag Gajin, Jovan Petrovic, Slobodan Pesic, Igor Atanasijevic, Aleksandar Babic, Mihailo Neskovic, Petar Dabic, Srdjan Babic, Predrag Matic, Slobodan Tanaskovic, Nenad Ilijevski
{"title":"Urgent carotid endarterectomy for crescendo transient ischemic attack.","authors":"Predrag Gajin, Jovan Petrovic, Slobodan Pesic, Igor Atanasijevic, Aleksandar Babic, Mihailo Neskovic, Petar Dabic, Srdjan Babic, Predrag Matic, Slobodan Tanaskovic, Nenad Ilijevski","doi":"10.1024/0301-1526/a001188","DOIUrl":"10.1024/0301-1526/a001188","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Carotid endarterectomy (CEA) is a widely accepted treatment to mitigate stroke risk in patients with severe carotid stenosis. The timing of CEA, especially in cases of acute neurological symptoms like crescendo transient ischemic attack (TIA) and stroke-in-evolution, remains contentious. This study evaluates the effectiveness of urgent CEA (UCEA) within 6 hours of crescendo TIA onset compared to elective CEA (ECEA) performed within 2 weeks in preventing recurrent stroke. <i>Patients and methods:</i> This retrospective study analyzed 87 patients with crescendo TIA treated with UCEA and compared them with a matched control group of 174 patients who underwent ECEA for symptomatic carotid disease. All patients underwent preoperative multidetector computed tomography angiography. Primary outcomes included mortality, stroke, TIA, and major adverse cardiac events within 30 days and up to 6 months postoperatively. <i>Results:</i> The UCEA group demonstrated no postoperative strokes or TIAs, with a low complication rate. UCEA resulted in one stroke within 6 months, with complete recovery. The ECEA group experienced one stroke and one death. There were no significant differences in early postoperative complications between the groups. However, the UCEA group exhibited a higher overall mortality rate (4.6% vs. 0.6%; p = 0.044), predominantly due to myocardial infarction. Both groups demonstrated comparable outcomes regarding postoperative complications and carotid restenosis at follow-up. <i>Conclusions:</i> UCEA performed within six hours of crescendo TIA shows comparable perioperative outcomes to ECEA in preventing recurrent strokes. While these findings suggest early intervention with UCEA may be a viable approach for patients with crescendo TIA, significant methodological limitations preclude definitive conclusions about safety and efficacy.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"259-264"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Carolina Gomes Inácio, Marlus Karsten, Luiza Carolina de Azevedo Santos, Rafael Dias de Brito Oliveira, Danielle Aparecida Gomes Pereira
{"title":"Diagnostic test accuracy of the walking impairment questionnaire in individuals with intermittent claudication.","authors":"Maria Carolina Gomes Inácio, Marlus Karsten, Luiza Carolina de Azevedo Santos, Rafael Dias de Brito Oliveira, Danielle Aparecida Gomes Pereira","doi":"10.1024/0301-1526/a001190","DOIUrl":"10.1024/0301-1526/a001190","url":null,"abstract":"<p><p><b></b> <i>Background:</i> The use of questionnaires in vascular rehabilitation has increased. The Walking Impairment Questionnaire (WIQ) can identify functional risk due to peripheral arterial disease (PAD). This study aimed to assess the accuracy of the WIQ for identifying individuals with PAD and intermittent claudication with low functional capacity. <i>Patients and methods:</i> A cross-sectional diagnostic test accuracy study was conducted. The Incremental Shuttle Walk Test (ISWT) assessed the distance walked, and the WIQ, the index test, evaluated the perception of functional capacity. Three reference values in the ISWT were defined: 380 m, 210 m (25th percentile), and 100 m. The accuracy, sensitivity, and specificity of the WIQ were tested using the Receiver Operating Characteristic curve and an alpha of 5% defined statistical significance. <i>Results:</i> One hundred and twenty-one volunteers participated in the study (64 ± 9.7 years, 65% men). The average distance in the ISWT was 270.6 ± 100.2 m. The WIQ scores were: mean 29.7 (14.0-50.2), distance (19; 6.3-47.8), walking speed (25; 13.0-43.5), and stairs (41.7; 12.5-75.0). The WIQ cut-off point for the ISWT references was 1) 37 for 380 m, with a sensitivity of 0.75 and specificity of 0.62 (AUC: 0.73, p=0.003; 95% CI 0.61 to 0.86); 2) 23 for 25th percentile (210 m), with a sensitivity of 0.75 and specificity of 0.70 (AUC: 0.77, p<.0001; 95% CI 0.68 to 0.86) and 3) 14 for 100 m, with a sensitivity of 0.78 and specificity of 0.83 (AUC: 0.77, p=.0001; 95% CI 0.64 to 0.91). <i>Conclusions:</i> The WIQ is helpful as a screening tool in research and clinical practice of PAD. The WIQ score with the best accuracy to identify individuals with low functional capacity was 14.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"253-258"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined chocolate drug-coatedballoon treatment of femoropopliteal artery lesions in patients with Rutherford Grade 3-6.","authors":"Xinyi Gao, Lianrui Guo, Xixiang Gao, Jianming Guo, Shijun Cui, Zhu Tong, Yongquan Gu","doi":"10.1024/0301-1526/a001196","DOIUrl":"10.1024/0301-1526/a001196","url":null,"abstract":"<p><p><b></b> <i>Background:</i> To investigate the efficacy of Chocolate balloon use as an adjunct to drug-coated balloon (DCB) angioplasty for the treatment of femoropopliteal lesions. <i>Patients and methods:</i> This retrospective study was performed with a 12-month follow-up period. The rate of flow-limiting dissection, primary patency, rate and length of bailout stenting, and freedom from major adverse limb events (MALEs) were compared between femoropopliteal lesions treated with plain balloons (PBs) and those treated with Chocolate balloons combined with DCB angioplasty. <i>Results:</i> In total, 192 patients (197 de-novo lesions) were included: 137 patients (141 lesions) in the PB group and 55 patients (56 lesions) in the Chocolate balloon group. The mean total lesion lengths were 126.84±71.57 and 138.39±65.35 mm (P=0.297), more than half of patients had chronic total occlusion (53.2% and 51.8%, P=0.859), the rates of flow-limiting dissection were 15.6% and 12.5% (P=0.579). Rates of primary patency were 88.1% and 92.6%, respectively. Chocolate balloon use reduced the mean total bailout stenting length (135.17±68.85 vs. 98.24±36.78 mm, P=0.022), including in complex lesions (180±70.43 vs. 102.50±44.64 mm, P=0.011), and the absolute bailout stenting length (total bailout stenting/lesion length ratio; 0.74±0.24 vs. 0.48±0.19, P=0.017). <i>Conclusions:</i> Relative to PB, Chocolate balloon use combined with DCB angioplasty did not show a significant advantage. It did, however, reduce the absolute total bailout stenting length in complex lesions.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"265-272"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infrapopliteal bypass surgery in the endovascular era.","authors":"Selina Dittrich, Briain Haney, Ulrich Rother, Livia Cotta, Ursula Werra, Bernhard Dorweiler, Farzin Adili, Christian-Alexander Behrendt","doi":"10.1024/0301-1526/a001210","DOIUrl":"https://doi.org/10.1024/0301-1526/a001210","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Over the past decade the increasing adoption of endovascular-first strategies has significantly altered the landscape in the treatment of peripheral arterial disease (PAD), raising concerns about the continuation and future development of high-quality surgical training, particularly in regard to tibial and pedal bypass procedures. This study aims to assess the current surgical and endovascular experience among the community of German vascular surgery program directors. <i>Materials and methods:</i> This study consisted of a questionnaire-based survey among German vascular surgeons who are licensed to provide further training in vascular surgery (in 2024). The aim was to assess participant's clinical experience, technical approaches to bypass surgery, decision making algorithms to revascularization procedures, and perceived adequacy of training in vascular surgery. <i>Results:</i> A total of 272 (77.7%) of the 350 invited surgeons responded, including 19 females (7.0%). The majority of the participants worked at academic teaching hospitals (79.8%), while 9.2% were in university hospitals and 11.0% worked at non-teaching hospitals. The median number of below-the-knee bypasses performed per career was 524 (IQR 286-1002), including 57 (IQR 20-129) pedal bypasses. Academic teaching hospitals reported the highest number of bypasses (601 vs. 300 in university hospitals) and non-teaching hospitals reported the highest number of endovascular procedures (786 vs. 301). Although the majority reported high confidence levels in performing said procedures, a considerable heterogeneity existed in technical aspects such as intraoperative anticoagulation, clamping technique, and post-surgical quality control. There was no association between institution type and technical aspects. One-third of respondents were over 60 years of age and therefore close to retirement age. <i>Conclusions:</i> This survey provided valuable insights into the delivery of vascular surgery programs in Germany, revealing a high variability in surgical experience, techniques, and training exposure. With an aging workforce and the further evolution of endovascular techniques, structured mentorship programs and standardized training curricula are essential to tackle the challenge of ensuring vascular surgeons remain proficient in tibial and pedal bypass surgery.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oliver Schlager, Elena Campello, Juraj Madaric, Jill Belch, Lucia Mazzolai, Marianne Brodmann, Michael Lichtenberg, Domenico Baccellieri, Christos Rammos, Christine Espinola-Klein, Christian Heiss, Markus Theurl, Leyla Schweiger, Tine De Backer, Mislav Vrsalovic, Petr Varejka, Sophie Blaise, Nikolaos Ptohis, Balasz Nemes, Marzia Lugli, Agata Stanek, Dan Olinic, Ivar Vacula, Vinko Boc, Pablo Demelo Rodríguez, Moncef Zarrouk, Marc Righini
{"title":"2025 ESVM Guidelines on interventional treatment of venous thromboembolism.","authors":"Oliver Schlager, Elena Campello, Juraj Madaric, Jill Belch, Lucia Mazzolai, Marianne Brodmann, Michael Lichtenberg, Domenico Baccellieri, Christos Rammos, Christine Espinola-Klein, Christian Heiss, Markus Theurl, Leyla Schweiger, Tine De Backer, Mislav Vrsalovic, Petr Varejka, Sophie Blaise, Nikolaos Ptohis, Balasz Nemes, Marzia Lugli, Agata Stanek, Dan Olinic, Ivar Vacula, Vinko Boc, Pablo Demelo Rodríguez, Moncef Zarrouk, Marc Righini","doi":"10.1024/0301-1526/a001211","DOIUrl":"https://doi.org/10.1024/0301-1526/a001211","url":null,"abstract":"<p><p><b></b> The number of endovascular interventional procedures for catheter-based therapy (CBT) of acute venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), has been increasing over the past years. The development of more efficient thrombectomy systems for CBT of VTE has potentially enhanced the efficacy of interventional treatment of VTE. Nevertheless, indications for CBT of VTE, i.e. catheter-directed thrombolysis (CDT) or catheter-based mechanical thrombus removal, need to be established based on existing data and expert consensus. Vascular experts should be involved in the decision-making process on CBTs in patients with acute VTE, and thrombus removal procedures should be performed in centers with experience in interventional treatment of VTE. This guideline document of the European Society of Vascular Medicine (ESVM) provides recommendations on indications and management of CBT in acute VTE and is endorsed by the European national societies of Vascular Medicine.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hagen Kerndl, Viktoria Peters, Alexander Hyhlik-Dürr, Dominik Liebetrau
{"title":"Safety and efficiency of the Gore Viabahn VBX as a bail-out option in complex vascular procedures.","authors":"Hagen Kerndl, Viktoria Peters, Alexander Hyhlik-Dürr, Dominik Liebetrau","doi":"10.1024/0301-1526/a001206","DOIUrl":"https://doi.org/10.1024/0301-1526/a001206","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Endovascular treatments in emergency or bailout situations focusing on anatomical regions with high extension and flexion movement remain a key area of interest. To date, the main field of application of the GORE<sup>®</sup> VIABAHN<sup>®</sup> VBX Balloon Expandable Endoprosthesis (VBX) (Gore, USA) has been in complex iliac occlusions and aortic pathologies. This retrospective study aimed to assess the safety and effectiveness of the VBX in a real-world patient population at a single centre, focusing on anatomical regions under high mechanical stress. This study presents the first data set for the VBX beyond its use in aortic and iliac pathologies. <i>Materials and methods:</i> In this retrospective monocentric study, all patients included had a Gore<sup>®</sup> Viabahn<sup>®</sup> balloon expandable (VBX<sup>®</sup>) implanted at a tertiary referral hospital during the observation period 02/2020 to 03/2024. <i>Results:</i> The median population age was 69 years, and eight patients were female. The mean Body Mass Index was 26,2±4,9 kg/m<sup>2</sup>. Eleven patients were treated in the inguinal region, nine in the shoulder region, and two in the knee region. The most common indications for implantation were stenosis (9/21) and bleeding (6/18). Eleven patients had an urgent need for implantation. Technical success was 100%. No stent-associated complication was observed. The 30-day mortality rate was 0%. The median follow-up time for all patients was 230 days (27-1064 d). Primary patency for all patients was 95,2%, while secondary patency was 100%. <i>Conclusions:</i> The VBX represents a safe and easy-to-use stent graft for managing complications, even in challenging anatomy regions.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}