VNU Journal of Science: Medical and Pharmaceutical Sciences最新文献_第3页

Modulatory Effects of Ginsenoside Saponins in Panax notoginseng on Steroid Hormones 人参皂甙对类固醇激素的调节作用

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-12-22 DOI: 10.25073/2588-1132/vnumps.4567

N. Van Khanh, Nguyen Thi Thanh Hai, Seijiro Homma, Vu Thi Thu Giang

{"title":"Modulatory Effects of Ginsenoside Saponins in Panax notoginseng on Steroid Hormones","authors":"N. Van Khanh, Nguyen Thi Thanh Hai, Seijiro Homma, Vu Thi Thu Giang","doi":"10.25073/2588-1132/vnumps.4567","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4567","url":null,"abstract":"Natural compounds with structural similarities to endogenous hormones, such as alkaloids, coumestans, flavonoids, lignans, saponins, and stilbenes, have been recognized increasingly for their potential in preventing and treating endocrine disorders related to steroid hormones. Panax notoginseng (Burk.) F. H. Chen, a member of the Araliaceae family and commonly known as Sanqi or Tianqi, is a valuable herbal medicine used to treat various diseases. The majority of saponins (ginsenosides) found in Panax notoginseng belongs to the dammarane triterpenoid group, exhibiting beneficial biological effects, including the treatment of cardiovascular diseases, pain, inflammation, and injuries, as well as internal and external bleeding caused by injury. The aglycone portion of ginsenosides possesses a steroid-like hydrophobic four-ring structure, similar to steroid hormones. Recent studies have indicated that the Panax notoginseng ginsenoside saponins (PNS) have steroid hormone-like activities, bringing the potential for endocrine disorders treatment. Thus, this review aims to provide the chemical structure and steroid hormone-regulating effects of ginsenoside saponins in Panax notoginseng. Keywords: Panax notoginseng, saponin, steroid hormone, ginsenoside, hormone-like effect.","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139164965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of Exacerbation and Antibiotic Usage in Treatment for Exacerbation of COPD Patients in National Lung Hospital (2022-2023) 2022-2023年国立肺科医院慢性阻塞性肺病患者急性加重特点及抗生素使用情况分析

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-11-02 DOI: 10.25073/2588-1132/vnumps.4570

Hoang Thu Huyen, Nguyen Kim Cuong, Le Thi Luyen

{"title":"Characteristics of Exacerbation and Antibiotic Usage in Treatment for Exacerbation of COPD Patients in National Lung Hospital (2022-2023)","authors":"Hoang Thu Huyen, Nguyen Kim Cuong, Le Thi Luyen","doi":"10.25073/2588-1132/vnumps.4570","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4570","url":null,"abstract":"Abstract: Exacerbations of COPD are important events in the progression of the disease, being the leading cause of hospitalization and mortality. Bacterial respiratory infections are one of the main causes of exacerbations. This retrospective study was described characteristics of exacerbation and antibiotic use in COPD exacerbation patients hospitalized at the National Lung Hospital. This study included 200 hospitalized patients from January2022 to June 2023. Many patients in the study sample were male (90%), 76% of patients had two or more exacerbations per year. The most isolated bacteria are Haemophilus influenzae, Pseudomonas aeruginosa, Acinetobacter baumannii. There were 77,5% pneumonia patients had Drug Susceptibility Tests (DST), and 54,7% of patients had antibiotic regimens consistent with the DST. The results of this study provide a reliable basis for selecting and improving the effectiveness of antibiotic use in the treatment of COPD exacerbations, improving outcomes and survival prognosis for patients. Keywords: COPD, exacerbation, bacteria, antibiotics.","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"11 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135935060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation and Acute Toxicity, Anti-Inflammatory, Analgesic Effects of Hard Capsules of Herba Siegesbeckiae Orientalis Dry Extract in Experimental Animals 荆芥干提取物硬胶囊的配方及对实验动物的急性毒性、抗炎、镇痛作用

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-11-02 DOI: 10.25073/2588-1132/vnumps.4555

Tran Thi Van Anh, Pham Quoc Tuan, Nguyen Van Khanh, Dao Viet Hung, Nguyen Thanh Hai, Ngo Thi Xuan Thinh, Ha Thanh Hoa, Dang Kim Thu, Nguyen Thi Thuy Linh, Nguyen Thu Quynh

{"title":"Formulation and Acute Toxicity, Anti-Inflammatory, Analgesic Effects of Hard Capsules of Herba Siegesbeckiae Orientalis Dry Extract in Experimental Animals","authors":"Tran Thi Van Anh, Pham Quoc Tuan, Nguyen Van Khanh, Dao Viet Hung, Nguyen Thanh Hai, Ngo Thi Xuan Thinh, Ha Thanh Hoa, Dang Kim Thu, Nguyen Thi Thuy Linh, Nguyen Thu Quynh","doi":"10.25073/2588-1132/vnumps.4555","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4555","url":null,"abstract":"This study aimed to investigate the acute toxicity, analgesic and anti-inflammatory effects of hard capsules containing dry extract from Siegesbeckia orientalis L. (CKHT) in animal models. Hard capsules were prepared using the volumetric method, with Avicel PH 102 as the diluent excipient and magnesium carbonate as the adsorbent excipient. The acute toxicity of CKHT was assessed on white mice at a dose of 2,400 mg/kg body weight. The anti-inflammatory effect was evaluated using a carrageenan-induced paw edema model in rats, while the analgesic effect was tested using an acetic acid-induced writhing model in mice. The results showed that CKHT administered at the doses of 102.2 mg/kg/day, 204.4 mg/kg/day, and 408.8 mg/kg/day had significant anti-inflammatory effect on the carrageenan-induced rat paw edema model by reducing the paw volume and increasing the percentage of edema inhibition compared to the untreated group (p < 0.001). The dose of CKHT 408.8 mg/kg/day showed anti-inflammatory effects that similar to aspirin at the dose level of 200 mg/kg/day (p > 0.05). In the analgesic study, mice treated with CKHT at the doses of 188.7 mg/kg/day, 377.4 mg/kg/day, and 754.8 mg/kg/day had significant reduction in acetic acid-induced writhing within 30 minutes compared to the untreated group (p < 0.001). Furthermore, CKHT did not show acute toxicity (no LD50) at the dose of 2,400 mg/kg body weight. These results suggested that CKHT exhibited acute analgesic and anti-inflammatory effects in animal models. Keywords: Dried extract from Siegesbeckia orientalis L.; capsules; anti-inflammatory; analgesic.  ","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"3 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135935849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of Total Polyphenols, Total Flavonoids, and Evaluation of Antioxidant Activity of the Aerial Part of Distichochlamys orlowii K. Larsen & M.F. Newman 黄芪地上部总多酚、总黄酮含量测定及抗氧化活性评价纽曼第一

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-10-24 DOI: 10.25073/2588-1132/vnumps.4530

Nguyem Xuan Tung, Nguyen Thanh Hai, Le Thi Hong, Nguyen Thi Van Anh, Le Hong Luyen

{"title":"Quantification of Total Polyphenols, Total Flavonoids, and Evaluation of Antioxidant Activity of the Aerial Part of Distichochlamys orlowii K. Larsen & M.F. Newman","authors":"Nguyem Xuan Tung, Nguyen Thanh Hai, Le Thi Hong, Nguyen Thi Van Anh, Le Hong Luyen","doi":"10.25073/2588-1132/vnumps.4530","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4530","url":null,"abstract":"Distichochlamys orlowii K. Larsen & M.F. Newman is a type of ginger endemic to Vietnam with high values of usage. This study aims to evaluate the total phenolic content, total flavonoid content, and antioxidant effect of the aerial part of Distichochlamys orlowii. The medicinal samples were extracted by ultrasonic method with different solvents including methanol, ethanol, ethyl acetate, and dichloromethane. The total phenolic content was evaluated using the Folin-Ciocalteu reagent and the total flavonoid content was evaluated by the aluminum chloride colorimetric method. The in vitro antioxidant effects of extracts were investigated through free radical scavenging models with DPPH and ABTS. The obtained results showed that the ethanol extract contained the highest content of total phenolic content and total flavonoid content with values of 12.81 ± 0.05% and 19.52 ± 0.23%, respectively. Meanwhile, the methanol extract exhibited the strongest DPPH and ABTS free radical scavenging activities with IC50 values of 243.89 ± 5.98 µg/mL and 33.58 ± 3.14 µg/mL, accordingly. The IC50 values of positive controls were 7,88 ± 0,25 µg/mL for the former assay and 9,74 ± 0,36 µg/mL for the latter assay. This is the first report on the chemical composition and antioxidant activity of the extracts from the aerial part of Distichochlamys orlowii.   ","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"62 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135273048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Process of Preparing 3-methyl-6-nitro-1H-indazole by Scale of 180 g/batch as an Important Intermediate for the Preparation of Pazopanib 180 g/批标度制备3-甲基-6-硝基- 1h -茚唑制备帕唑帕尼重要中间体的工艺研究

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-10-24 DOI: 10.25073/2588-1132/vnumps.4540

Văn Hải Nguyễn, Thị Thanh Châm Bùi, Quốc Hùng Phan, Trà Ly Trần, Thị Ngọc Nguyễn, Thị Luyến Bùi, Thu Quỳnh Nguyễn, Nguyệt Sương Huyền Đào, Đình Luyện Nguyễn, Văn Giang Nguyễn

{"title":"Process of Preparing 3-methyl-6-nitro-1H-indazole by Scale of 180 g/batch as an Important Intermediate for the Preparation of Pazopanib","authors":"Văn Hải Nguyễn, Thị Thanh Châm Bùi, Quốc Hùng Phan, Trà Ly Trần, Thị Ngọc Nguyễn, Thị Luyến Bùi, Thu Quỳnh Nguyễn, Nguyệt Sương Huyền Đào, Đình Luyện Nguyễn, Văn Giang Nguyễn","doi":"10.25073/2588-1132/vnumps.4540","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4540","url":null,"abstract":"Pazopanib hydrochloride, marketed worldwide under the brand name Votrient, is an anti-cancer medication manufactured by Novartis. It is the first and only tyrosine kinase inhibitor currently approved for the treatment of multiple histological subtypes of soft tissue sarcoma (STS). In previous studies, we presented initial results regarding the synthesis of 3-methyl-5-nitro-2H-indazole (3) as an important indazole component on a laboratory scale (approximately 10 g/batch). In this study, we have successfully synthesized this compound (3) at a scale of 200 g/batch, achieving an overall process yield of 79.6 % from the starting material ethylaniline. This yield is higher than that reported in previous publications. Some of the technical conditions that have been improved include optimizing the amount of sulfuric acid in the nitration reaction, the amount of acetic acid, sodium hydroxide in the diazotization reaction for ring closure, reaction temperature, and the feed method to control the reaction safely and achieve high efficiency at a scale of 200 g/batch.","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"16 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135268448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal Screening Characteristics of Edward’s and Patau’s Syndrome in the First Trimester at the National Hospital of Obstetrics and Gynecology 国家妇产医院妊娠早期爱德华综合征和帕托综合征的产前筛查特点

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-10-24 DOI: 10.25073/2588-1132/vnumps.4542

Nguyen Thi Trang, Tran Danh Cuong, Do Thi Quynh, Vu Van Nga, Han Minh Thuy, Ngo Toan Anh, Nguyen Hoang Phi, Le Thi Minh Phuong

{"title":"Prenatal Screening Characteristics of Edward’s and Patau’s Syndrome in the First Trimester at the National Hospital of Obstetrics and Gynecology","authors":"Nguyen Thi Trang, Tran Danh Cuong, Do Thi Quynh, Vu Van Nga, Han Minh Thuy, Ngo Toan Anh, Nguyen Hoang Phi, Le Thi Minh Phuong","doi":"10.25073/2588-1132/vnumps.4542","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4542","url":null,"abstract":"Edward and Patau syndromes are severe genetic abnormalities. The consequences of these syndromes are often fatal in the fetus and neonate. Prenatal screening for these syndromes is important for early detection of birth defects. 212 medical records of pregnant women with normal pregnancies were selected using convenience sampling. Selection of 34 cases of Edward or Patau pregnancy using a total sampling technique. We conducted a descriptive retrospective study to describe and compare various markers related to prenatal screening to establish the most appropriate diagnostic criteria. A history of spontaneous abortion is associated with an increased risk of subsequent pregnancies with Edward's or Patau's syndrome. The nuchal translucency value was mainly concentrated below 2 mm, lower than the values observed in Trisomy 18 and 13 cases, predominantly in the 2-3 mm range. A threshold of 2.5 mm for nuchal translucency measurement had the highest detection rate for Edwards and Patau syndromes, and abnormal fetal heart rate was most commonly observed in trisomy cases on ultrasound examination. The MoM fβ-hCG concentration in the Edwards and Patau groups was predominantly concentrated in the low range (≤1), while the normal group showed a higher concentration in the range of 1-3. The MoM PAPP-A concentration in the normal group was commonly found in the range of 0.5-1, which was higher compared to the trisomy group.   ","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"C-19 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135273210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Situation and Factors Related to Stress, Anxiety, and Depression of Pharmaceutical Personnel at Some District Public Health Facilities in Can Tho City, Vietnam in 2021-2022 2021-2022年越南芹苴市部分地区公共卫生机构药学人员压力、焦虑、抑郁现状及相关因素分析

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-09-24 DOI: 10.25073/2588-1132/vnumps.4499

Nguyen Phuc Hung, Le Dieu Phap, Phung Phi Yen, Cao Huynh Phong, Vo Thi My Huong

{"title":"Current Situation and Factors Related to Stress, Anxiety, and Depression of Pharmaceutical Personnel at Some District Public Health Facilities in Can Tho City, Vietnam in 2021-2022","authors":"Nguyen Phuc Hung, Le Dieu Phap, Phung Phi Yen, Cao Huynh Phong, Vo Thi My Huong","doi":"10.25073/2588-1132/vnumps.4499","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4499","url":null,"abstract":"During the COVID-19 pandemic, there were numerous studies conducted around the world on stress, depression, and anxiety in medical personnel. However, the research on pharmaceutical staff, who are also a significant contributing force in prevention at the hospital, is still limited. The study was carried out by a cross-sectional descriptive method. A total of 125 pharmacy staff working at the medical facilities were directly interviewed. The χ2 test was used to test the relationship between factors with α = 0.05, and the odds ratio (OR) with a 95% confidence interval was calculated. The obtained results showed that the percentages of stress, anxiety, and depression among pharmacy staff were 67.2%, 12.0%, and 10.4%, accordingly. Situational stress, anxiety, and depression correlated to education levels, monthly income, and weekly working time. This research emphasized the importance of mental health care for health workers. It promoted the state management agency to organize training courses and share soft skills with pharmaceutical staff to overcome difficulties and bad psychology while on duty at the department.","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135926444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence Rateand Risk Factors of Central Line-Associated Bloodstream Infection 中央线相关血流感染的发生率及危险因素

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-09-24 DOI: 10.25073/2588-1132/vnumps.4471

Duong Thi Huong Hao, Tran Minh Dien, Le Thi Ha, Cao Viet Tung

引用次数: 0

Hemodynamic and Homeostasis Changes after Continuous Renal Replacement Therapy in Septic Shock Children at Vietnam National Children’s Hospital 越南国立儿童医院感染性休克儿童持续肾脏替代治疗后血液动力学和体内平衡的变化

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-09-24 DOI: 10.25073/2588-1132/vnumps.4534

Tong Duy Phuc, Tran Ba Dung, Dau Viet Hung, Ta Anh Tuan, Thieu Quang Quan, Phan Huu Phuc

{"title":"Hemodynamic and Homeostasis Changes after Continuous Renal Replacement Therapy in Septic Shock Children at Vietnam National Children’s Hospital","authors":"Tong Duy Phuc, Tran Ba Dung, Dau Viet Hung, Ta Anh Tuan, Thieu Quang Quan, Phan Huu Phuc","doi":"10.25073/2588-1132/vnumps.4534","DOIUrl":"https://doi.org/10.25073/2588-1132/vnumps.4534","url":null,"abstract":"Objectives: This study aims to describe changes in hemodynamics and homeostasis after continuous renal replacement therapy (CRRT) in septic shock children without acute kidney injury. Methods: An observational study was conducted in the pediatric intensive care unit (PICU) at Vietnam National Children’s Hospital from January 2018 to June 2022. Children aged under 18 years old with septic shock and without acute kidney injury who required CRRT were analyzed on demographic factors, baseline clinical and laboratory results, changes in hemodynamics and homeostasis at 6 hours, 12 hours, 24 hours, 48 hours, 72 hours, 4 days and 5 days after CRRT initiation. Results: A total of 125 children (male, 57.6%) were enrolled in the study. The median age was 11.5 months (IQR: 5 – 29). Overall PICU mortality rate at day 28 was 40.8%. Among survivors, there was a statistically significant improvement in heart rate, mean blood pressure, vasoactive inotropic score (VIS), and pH at all mentioned periods after CRRT initiation. Lactatemia statistically significantly decreased after 24 hours of CRRT initiation (p < 0.05). Among non-survivors, there was a statistically significant improvement in heart rate at all the periods and in mean blood pressure at 6 hours and 12 hours, while there was no improvement in VIS, pH, and lactatemia. Conclusion: CRRT played an important role in stabilizing hemodynamics and homeostasis in septic shock children without acute kidney injury.   ","PeriodicalId":23520,"journal":{"name":"VNU Journal of Science: Medical and Pharmaceutical Sciences","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135926219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental Health Literacy Among Residents in Hien Chung Commune, Quan Hoa District, Thanh Hoa Province in 2022 2022年清化省泉化区显忠公社居民心理健康素养调查

VNU Journal of Science: Medical and Pharmaceutical Sciences Pub Date : 2023-09-24 DOI: 10.25073/2588-1132/vnumps.4531

Mac Dang Tuan, Le Thi Tinh, Le Thi Kim Chi, Le Thi Thu Hien, Nguyen Xuan Bach

引用次数: 0