Incidence Rateand Risk Factors of Central Line-Associated Bloodstream Infection

Objective: Determination of incidence rates and some risk factors for Central Line-Associated Bloodstream Infection (CLABSI) at the Neonatal Center of Vietnam National Children's Hospital. Methods: 416 neonates who were inserted central line from 01/01/2021 to 30/06/2022 were enrolled in our study. CLABSI was defined as CDC 2017 criteria (LCBI3). The primary factors included obstetric history, perinatal history, characteristics of catheters, duration of catheter placement, etc. Result: A total of 672 central lines were placed in 416 infants. Of these, 32 CLABSI cases were identified. Rates of CLABSI was 5.7 infections per 1000 catheter days. Predisposing factors included duration of catheter placement of more than 28 days (OR = 2.9; 95% CI: 1.03 – 8), abdominal condition (OR = 5.3; 95% CI: 1.5 – 18.6) and steroid used (OR 5.3; CI 1.98 – 14.3). Conclusion: The “CLABSI prevention package” was effective in reducing the CLABSI rate and could be applied in other hospitals.