Veterinary Medicine International最新文献_第8页

Impact of Using Processed Urinary Bladder Submucosa and Hydrogel Fabricated from Tendon on Skin Healing Process in Rabbits. 使用加工过的膀胱粘膜和由肌腱制成的水凝胶对兔子皮肤愈合过程的影响

IF 3.1

Veterinary Medicine International Pub Date : 2024-02-06 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6641975

Majid A Alkhilani, Omar Tariq Hammoodi, Hasanain Abduljabbar Emran, Wissam Abdullah Alhayani

{"title":"Impact of Using Processed Urinary Bladder Submucosa and Hydrogel Fabricated from Tendon on Skin Healing Process in Rabbits.","authors":"Majid A Alkhilani, Omar Tariq Hammoodi, Hasanain Abduljabbar Emran, Wissam Abdullah Alhayani","doi":"10.1155/2024/6641975","DOIUrl":"10.1155/2024/6641975","url":null,"abstract":"This study was intended to evaluate the healing of skin injury by using decellularized urinary bladder submucosa scaffolds and tendon-derived hydrogel. Thirty-six adult local breeds of both sex rabbits, with an average weight of 2.0-2.5 kg, were divided randomly into three groups (12 animals for each group). All groups were subjected to an induced injury (2 cm) in diameter at the right side of the abdominal skin, the rabbits of the 1st group (A) were sutured without the application of any substance as a control group, the rabbits of the 2nd group (B) were sutured and treated with the application of decellularized urinary bladder submucosa scaffolds, and in the 3rd group (C), they were sutured and treated with the application of tendon-derived hydrogel. Postoperative care following had been done for all groups throughout the study period. Specimens from the injured skin were taken for the histopathological study on the postinjury day, 8th, 14th, 21st, and 24th. The study showed a clear effect of materials used in the treatment of wounds through a clear progression in the healing stages with a noticed superiority of the submucosa scaffold group.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"6641975"},"PeriodicalIF":3.1,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Parameters of Semen Traits and Their Correlations with Conformation Traits in Chinese Holstein Bulls. 中国荷斯坦公牛精液性状的遗传参数及其与体形性状的相关性

IF 3.1

Veterinary Medicine International Pub Date : 2024-01-29 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5593703

Xiao Wang, Jian Yang, Jie Xue, Miao Zhang, Fan Zhang, Kun Wang, Yanqin Li, Yuanpei Zhang, Xiaoping Wu, Feng Wang, Xiuxin Zhao, Junqing Ni, Yabin Ma, Rongling Li, Lingling Wang, Guosheng Su, Yundong Gao, Jianbin Li

{"title":"Genetic Parameters of Semen Traits and Their Correlations with Conformation Traits in Chinese Holstein Bulls.","authors":"Xiao Wang, Jian Yang, Jie Xue, Miao Zhang, Fan Zhang, Kun Wang, Yanqin Li, Yuanpei Zhang, Xiaoping Wu, Feng Wang, Xiuxin Zhao, Junqing Ni, Yabin Ma, Rongling Li, Lingling Wang, Guosheng Su, Yundong Gao, Jianbin Li","doi":"10.1155/2024/5593703","DOIUrl":"10.1155/2024/5593703","url":null,"abstract":"The elite bull plays an extremely important role in the genetic progression of the dairy cow population. The previous results indicated the potential positive relationship of large scrotal circumference (SC) with improved semen volume, concentration, and motility. In order to improve bull's semen quantity and quality by selection, it is necessary to estimate the genetic parameters of semen traits and their correlations with other conformation traits such as SC that could be used for an indirect selection. In this study, the genetic parameters of seven semen traits (n = 66,260) and nine conformation traits (n = 3,642) of Holstein bulls (n = 453) were estimated by using the bivariate repeatability animal model with the average information-restricted maximum likelihood (AI-REML) approach. The results showed that the estimated heritabilities of semen traits ranged from 0.06 (total number of motile sperm, TNMS) to 0.37 (percentage of abnormal sperm, PAS) and conformation traits ranged from 0.23 (pin width, PW) to 0.69 (hip height, HH). The highest genetic correlations were found between semen volume per ejaculation (SVPE), semen concentration per ejaculation (SCPE), total number of sperm (TNS), and TNMS traits that were 0.97, 0.98, 1.00, and 0.99, respectively. Phenotypic correlations between SC and SVPE, SCPE, TNS, and TNMS were 0.35, 0.35, 0.48, and 0.42, respectively. In summary, the moderate or high heritability of semen traits indicates that genetic improvement of semen quality by selection is feasible, where SC could be a useful trait for indirect selection or as correlated information to improve semen quantity and production in the practical bull breeding programs.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"5593703"},"PeriodicalIF":3.1,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 3.1

Veterinary Medicine International Pub Date : 2024-01-13 eCollection Date: 2024-01-01 DOI: 10.1155/2024/4107326

María Paula Herrera-Sánchez, Roy Rodríguez-Hernández, Iang Schroniltgen Rondón-Barragán

{"title":"Stress-Related Gene Expression in Liver Tissues from Laying Hens Housed in Conventional Cage and Cage-Free Systems in the Tropics.","authors":"María Paula Herrera-Sánchez, Roy Rodríguez-Hernández, Iang Schroniltgen Rondón-Barragán","doi":"10.1155/2024/4107326","DOIUrl":"10.1155/2024/4107326","url":null,"abstract":"Global egg production is mainly based on cage systems, which have been associated with negative effects on the welfare of birds. Stress factors in restrictive production systems can lead to changes in gene transcription and protein synthesis, ultimately impacting the quality of poultry products. The liver serves various metabolic functions, such as glycogen storage, and plays a crucial role in animals' adaptation to environmental changes. Consequently, both internal and external conditions can influence liver functions. The aim of this study was to evaluate the gene expression of AGP, CRP, NOX4, SOD1, CAT, GPX1, SREBF1, and FXR in the liver of laying hens under two different production systems. Liver tissues from Hy-Line Brown hens housed in conventional cage and cage-free egg production systems at 60 and 80 weeks of production were used. mRNA transcript levels were determined by qPCR using the relative quantification method and ACTB as the reference gene. AGP, SOD1, and SREBF1 gene expressions were significantly higher in the conventional cage group at the 60 weeks of production. Furthermore, the mRNA levels of transcripts related to oxidative stress and lipid metabolism were higher in the group of laying hens housed in conventional cages compared to those in cage-free systems. These results suggest differential gene expression of genes related to oxidative stress in liver tissues from hens housed in conventional cages compared to cage-free systems. The conditions of the egg production system can impact the gene expression of oxidative stress and lipid synthesis genes, potentially leading to changes in the metabolism and performance of hens, including egg quality.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"4107326"},"PeriodicalIF":3.1,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10799707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139511957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biting Flies and Associated Pathogens in Camels in Amibara District of Afar Region, Ethiopia 埃塞俄比亚阿法尔地区阿米巴拉县骆驼中的叮蝇及相关病原体

IF 3.1

Veterinary Medicine International Pub Date : 2024-01-09 DOI: 10.1155/2024/5407898

Adugna Chalchisa, B. Kumsa, Fekadu Gutema Wegi

{"title":"Biting Flies and Associated Pathogens in Camels in Amibara District of Afar Region, Ethiopia","authors":"Adugna Chalchisa, B. Kumsa, Fekadu Gutema Wegi","doi":"10.1155/2024/5407898","DOIUrl":"https://doi.org/10.1155/2024/5407898","url":null,"abstract":"Biting flies and associated pathogens are the major health constraints on camel production and productivity and are implicated in causing significant economic losses in the pastoralist community in Ethiopia. A cross-sectional study was conducted to estimate the prevalence of biting flies and their associated pathogens in relation to different risk factors in camels in the Amibara district, from October 2019 to April 2020. A total of 480 camels were examined for biting flies and associated pathogens. The study revealed that overall, 87% (418/480) and 18% (87/480) of camels were infested by one or more biting flies and infected with Trypanosoma evansi during the study period, respectively. The collected biting flies were identified into a total of 3 genera: Hippobosca, Stomoxys, and Tabanus under the stereomicroscope. In the present study, Hippobosca (40.4%) was the most prevalent biting fly, followed by Stomoxys (31%) and Tabanus (28.6%), which affected camels in the study area. Among camels infected with Trypanosoma evansi, 7.3% and 16% were positive for parasitological and serological tests, respectively. Age, body condition score, and season appeared to have a significant effect (p≤0.005) on the prevalence of biting flies and T. evansi on dromedaries. According to the findings of this study, biting flies and Trypanosoma evansi were the most common limitations on camel health, production, and productivity in the study area. As a result of the possible threat of biting flies’ infestation and Trypanosoma evansi on camels, all-around attention is required in terms of strategic acaricide application, proper antiprotozoal drug use, and raising knowledge about acaricide use to prevent and control biting flies’ infestation.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"11 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139441696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial and Seasonal Patterns of Tick Infestations in Kassena-Nankana Livestock 卡塞纳-南卡纳牲畜蜱虫感染的空间和季节模式

IF 3.1

Veterinary Medicine International Pub Date : 2024-01-09 DOI: 10.1155/2024/8889907

Seth Offei Addo, Ronald Essah Bentil, Bernice Olivia Ama Baako, Jane Ansah-Owusu, Christopher Nii Laryea Tawiah-Mensah, E. Behene, V. Asoala, James C. Dunford, John Asiedu Larbi, Philip Kweku Baidoo, Michael David Wilson, J. Diclaro, S. Dadzie

{"title":"Spatial and Seasonal Patterns of Tick Infestations in Kassena-Nankana Livestock","authors":"Seth Offei Addo, Ronald Essah Bentil, Bernice Olivia Ama Baako, Jane Ansah-Owusu, Christopher Nii Laryea Tawiah-Mensah, E. Behene, V. Asoala, James C. Dunford, John Asiedu Larbi, Philip Kweku Baidoo, Michael David Wilson, J. Diclaro, S. Dadzie","doi":"10.1155/2024/8889907","DOIUrl":"https://doi.org/10.1155/2024/8889907","url":null,"abstract":"The ability of ticks to adapt to different ecological zones, coupled with the spread of infectious pathogens negatively affects livestock production and thus, there is a need for better control strategies. However, control measures within a geographical region can only be effective if there is available information on tick population dynamics and ecology. This study focused on ticks infesting livestock in the Kassena-Nankana Districts of the Upper East Region of Ghana. The ticks were morphologically identified, variables such as season, animal host, and predilection sites were recorded, and the data were analyzed using STATA version 13. Out of 448 livestock examined, tick infestation in cattle was (78.60%), followed by sheep (25%) and goats (5.88%). A total of 1,550 ticks including nymphs (303) and adults (1,247) were collected. Adult ticks were found to be significantly associated with season (p<0.001), with a high burden in the wet season. The nymph burden and body parts of livestock hosts were significantly associated with more nymphs collected from male animals than females (p<0.001). Three genera of ticks, Amblyomma (62.97%), Hyalomma (18.71%), and Rhipicephalus (18.32%) were morphologically identified with the most predominant tick species recorded as Amblyomma variegatum (62.97%). Matured A. variegatum was sampled primarily in the wet season with their predilection site as the udder/scrotum (p<0.001). However, adult Hyalomma truncatum was observed to have a significant association with the anal region (p<0.001). Findings from this study are essential for formulating tick control measures to prevent the spread of infectious pathogens.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"27 12","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139444115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation and Molecular Identification of Mycobacterium bovis from Slaughtered Cattle in Nekemte Municipality Abattoir, Ethiopia. 埃塞俄比亚 Nekemte 市屠宰场屠宰牛中牛分枝杆菌的分离和分子鉴定。

IF 3.1

Veterinary Medicine International Pub Date : 2023-12-16 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9911836

Tola Mezgebu Gemeda, Eyob Hirpa Tola, Balako Gumi Donde, Muse Girma Abdela, Hika Waktole Ayana

{"title":"Isolation and Molecular Identification of Mycobacterium bovis from Slaughtered Cattle in Nekemte Municipality Abattoir, Ethiopia.","authors":"Tola Mezgebu Gemeda, Eyob Hirpa Tola, Balako Gumi Donde, Muse Girma Abdela, Hika Waktole Ayana","doi":"10.1155/2023/9911836","DOIUrl":"https://doi.org/10.1155/2023/9911836","url":null,"abstract":"Tuberculosis (TB) is a zoonotic disease that can spread from animals to humans as well as from human to human. Little research has been conducted on bovine tuberculosis prevalence and molecular characterization in the western part of Ethiopia. To investigate this, a cross-sectional study was conducted on slaughtered cattle at the Nekemte municipal abattoir between January 2020 and June 2021. A detailed postmortem examination, culture, acid-fast staining technique, molecular characterization using RD4 deletion, and spoligotyping were all carried out. Based on a detailed postmortem examination, the overall prevalence of bovine tuberculosis was 7.8% (80 of 1020). Mycobacterium isolation confirmed only 12.5% (10/80) of the suspected tuberculosis tissue lesions. With acid-fast bacilli staining, all Mycobacterium spp. isolates (n = 10) were positive. However, only 9/10 isolates were confirmed to be M. bovis with RD4 molecular deletion typing. Spoligotyping revealed that 55.6% (5/9) of the isolate patterns had previously been reported, but 44.4% (4/9) of the isolates were new. In the current investigation, it was discovered that 80% (4/5) of the M. bovis strains circulating in the cattle population of study regions were SB2233 (2/5) and SB0134 (2/5), whereas 20% (1/5) of the strains corresponded to SB1176, which is compatible with previously documented M. bovis spoligotypes. These findings suggested that M. bovis was the main cause of bovine tuberculosis in the study area and posed a risk of disease transmission from cattle to humans due to low levels of public health awareness. As such, improved awareness among citizens and the development of control policies are warranted.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2023 ","pages":"9911836"},"PeriodicalIF":3.1,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10748727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial Resistance in Poultry Farming: A Look Back at Environmental Escherichia coli Isolated from Poultry Farms during the Growing and Resting Periods. 家禽养殖中的抗菌素耐药性:从家禽养殖场生长和休养期分离的环境大肠杆菌的回顾。

IF 3.1

Veterinary Medicine International Pub Date : 2023-11-28 eCollection Date: 2023-01-01 DOI: 10.1155/2023/8354235

Sukanya Thongratsakul, Patamabhorn Amavisit, Chaithep Poolkhet

{"title":"Antimicrobial Resistance in Poultry Farming: A Look Back at Environmental Escherichia coli Isolated from Poultry Farms during the Growing and Resting Periods.","authors":"Sukanya Thongratsakul, Patamabhorn Amavisit, Chaithep Poolkhet","doi":"10.1155/2023/8354235","DOIUrl":"10.1155/2023/8354235","url":null,"abstract":"During the production cycle of poultry farms, pathogens may remain in the next cycle of rearing young chickens. This study was conducted at three industrial chicken farms (A, B, and C) in central Thailand. Results showed that the percentages of E. coli during the resting period in farms A, B, and C were 28.6, 53.8, and 7.8, respectively, and those during the growing period were 45, 68.8, and 75. The most common resistant patterns during the resting period in all farms were AML-AMP-SXT and AML-AMP-DO-SXT, and those during the growing period were AML-AMP and AML-AMP-SXT. The locations of blaTEM-positive E. coli isolates from the inside houses (inside buildings) of all farms included cloacal swabs, floors, water nipples, pan feeders, and husks, whereas that from the outside environment included boots, wastewater, soil, and water from cooling pads and tanks. Our results indicate that the percentage of antimicrobial resistance (AMR) and its pattern depend on the husbandry period and the strictness of biosecurity. Moreover, our findings derived from samples gathered from broiler farms between 2013 and 2015 align with those of the current studies, highlighting persistent trends in E. coli resistance to various antimicrobial agents. Therefore, enhancing biosecurity measures throughout both the resting and growing periods is crucial, with a specific focus on managing raw materials, bedding, breeding equipment, and staff hygiene to reduce the transmission of antimicrobial resistance in poultry farms.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2023 ","pages":"8354235"},"PeriodicalIF":3.1,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Proportion of Brucella abortus and Brucella melitensis in Sheep and Goat Milk. 绵羊和山羊乳中流产布鲁氏菌和melitensis布鲁氏菌比例的调查。

IF 3.1

Veterinary Medicine International Pub Date : 2023-11-24 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6751152

Saeid Rostami, Ehsan Rashidian, Amin Jaydari, Heidar Rahimi

{"title":"Investigation of the Proportion of Brucella abortus and Brucella melitensis in Sheep and Goat Milk.","authors":"Saeid Rostami, Ehsan Rashidian, Amin Jaydari, Heidar Rahimi","doi":"10.1155/2023/6751152","DOIUrl":"10.1155/2023/6751152","url":null,"abstract":"Despite the implementation of brucellosis eradication programs in Iran, this disease is still endemic and highly prevalent among ruminants in this country. The infection of small ruminants with Brucella abortus may play a significant role in the continuation of brucellosis among the herds of ruminants. This study investigated the proportion of B. abortus and Brucella melitensis in 150 samples of sheep and goat's raw milk which were obtained from Lorestan and Hamadan provinces in the western part of Iran using the PCR method. The results revealed that among the Brucella spp. positive samples, 26.5% and 73.4% of the samples were infected with B. abortus and B. melitensis, respectively. The incidence rates of B. abortus among the sheep and goats samples were 6.8% and 12.5%, respectively. There was a significant difference between goats and sheep regarding the proportion of B. abortus. Three samples (2%) (2 goats and one sheep) were simultaneously infected with both B. melitensis and B. abortus. This article renews our knowledge about the causative agent of brucellosis in small ruminants and shows that B. abortus has a relatively high prevalence among those animals in the western regions of Iran, and its role as one of the main factors of abortion among small ruminants should not be ignored. The information provided in the present study is important for the surveillance program, as eradication programs and strategies to prevent the spread of B. abortus among small ruminants that have not been vaccinated against this microorganism may be adapted accordingly.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2023 ","pages":"6751152"},"PeriodicalIF":3.1,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review on Treatment of Premature Ovarian Insufficiency: Characteristics, Limitations, and Challenges of Stem Cell versus ExosomeTherapy. 卵巢早衰的治疗综述:干细胞与外泌体治疗的特点、局限性和挑战。

IF 3.1

Veterinary Medicine International Pub Date : 2023-11-17 eCollection Date: 2023-01-01 DOI: 10.1155/2023/5760011

Narges Elahi, Jafar Ai, Zohreh Makoolati

{"title":"A Review on Treatment of Premature Ovarian Insufficiency: Characteristics, Limitations, and Challenges of Stem Cell versus ExosomeTherapy.","authors":"Narges Elahi, Jafar Ai, Zohreh Makoolati","doi":"10.1155/2023/5760011","DOIUrl":"https://doi.org/10.1155/2023/5760011","url":null,"abstract":"Premature ovarian insufficiency (POI) is a complex disorder that can result in varying degrees of infertility. Recently, mesenchymal stem cell (MSC) therapy and its derivatives, such as exosomes, have been introduced as novel strategies for the treatment of POI. This review discusses the features, limitations, and challenges of MSC and exosome therapy in the treatment of POI and provides readers with new insights for comparing and selecting chemical agents, optimizing doses, and other factors involved in study design and treatment strategies. MSC therapy has been shown to improve ovarian function in some animals with POI, but it can also have side effects such as high cost, time-consuming processes, limited lifespan and cell sources, loss of original characteristics during in vitro proliferation, dependence on specific culture environments, potential immune reactions, unknown therapeutic mechanisms, etc. However, exosome therapy is a newer therapy that has not been studied as extensively as MSC therapy, but that it has shown some promise in animal studies. The evidence for the effectiveness of MSC and exosome therapy is still limited, and more research is needed to determine whether these therapies are effective and safe for women with POI. This study presents a new perspective for researchers to advance their research in the fields of cell-based and cell-free therapies.","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2023 ","pages":"5760011"},"PeriodicalIF":3.1,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138462900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamics of Feline Coronavirus and FIP: A Compartmental Modeling Approach. 猫冠状病毒和FIP的动力学:一种分区建模方法。

IF 3.1

Veterinary Medicine International Pub Date : 2023-11-17 eCollection Date: 2023-01-01 DOI: 10.1155/2023/2721907

Ayse Peker Dobie, Alper Bayrakal, Mehmet Erman Or, Ayse Humeyra Bilge

{"title":"Dynamics of Feline Coronavirus and FIP: A Compartmental Modeling Approach.","authors":"Ayse Peker Dobie, Alper Bayrakal, Mehmet Erman Or, Ayse Humeyra Bilge","doi":"10.1155/2023/2721907","DOIUrl":"https://doi.org/10.1155/2023/2721907","url":null,"abstract":"The investigation of infectious agents invading human and nonhuman populations represents a rich research domain within the framework of mathematical biology, captivating the interest of scientists across various disciplines. In this work, we examine the endemic equilibrium of feline coronavirus and feline infectious peritonitis by using a modified susceptible-infected-susceptible epidemiological model. We incorporate the concept of mutations from FCoV to FIP to enrich our analysis. We establish that the model, when subjected to reasonable parameter ranges, supports an endemic equilibrium wherein the FCoV group dominates. To demonstrate the stability of the equilibria under typical parameters and initial conditions, we employ the model SCF presented by Dobie in 2022 (Dobie, 2022). We ascertain that the equilibrium values reside within the interior domains of stability. Additionally, we displayed perturbed solutions to enhance our understanding. Remarkably, our findings align qualitatively with existing literature, which reports the prevalence of seropositivity to FCoV among stray cats (Tekelioglu et al. 2015, Oğuzoğlu et al. 2010, Pratelli 2008, Arshad et al. 2004).","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2023 ","pages":"2721907"},"PeriodicalIF":3.1,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138462902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0