Veterinary Medicine International最新文献

{"title":"The Weight of Genetic Drift: A Pedigree-Based Evaluation of the Breton Horse Population in Brazil.","authors":"Bruno B Medeiros, Kate M C Barcelos, Millena Oliveira Andrade, Michele Cristina da Paz Carvalho, Victoria Rocha Miranda, Kalebe de Oliveira Maia, Susana Reinhardt, Laura Patterson Rosa","doi":"10.1155/2024/4714077","DOIUrl":"10.1155/2024/4714077","url":null,"abstract":"<p><p>The genetic diversity of Breton horses in Brazil is a critical concern, mainly due to the small population size and low number of births per year. Given that the inbreeding was overlooked by breeders for multiple generations, we estimated the genetic diversity of this population utilizing pedigree-based measures of population diversity. A total of 1394 six-generation pedigrees representing the full population of registered Breton horses in Brazil defined a total population (TP, <i>N</i> = 2679), with horses born between 2000 and 2022, reproductively active and alive, as reported by the breed association, representing the reference population (RP, <i>N</i> = 731). Using the R package <i>PurgeR</i>, we estimated inbreeding coefficient (<i>F</i> _<i>ped</i> ), maternal inbreeding coefficient (<i>F</i> _{<i>da</i> <i>m</i>} ), paternal inbreeding coefficient (<i>F</i> _<i>sire</i> ), individual reproductive values, number of equivalents to complete generations (<i>t</i>), and unbiased ancestral inbreeding coefficient (<i>Fa</i>). We established the equivalent complete generations (ECG), effective population size (<i>Ne</i>), total number of founders (<i>Nf</i>), effective number of founders (<i>Nfe</i>), total number of ancestors (<i>Na</i>), effective number of ancestors (<i>Nae</i>), founder genomes (<i>Ng</i>), and the inbreeding coefficient estimated with effective population size (<i>Ne</i>) and generation numbers (<i>t</i>) (<i>F</i> _{<i>Ne</i>:<i>t</i>} ), as well as <i>Nfe</i>/<i>Nae</i> and <i>Nfe</i>/<i>Ng</i> ratios for the RP. The RP inbreeding levels have stabilized, although they are still significantly rising by generation (<i>t</i>), and the <i>Nfe</i>/<i>Ng</i> ratio strongly suggests genetic drift. Pedigree-based analysis demonstrates that only five stallions have sired 52.83% of the RP individuals, which along with the <i>Nae</i> value of 36.73 implies that the observed inbreeding can be arising from patrilines. Our results suggest that observed inbreeding is due to Popular Sire Effect, highlighting the importance of monitoring breeding schemes and genetic diversity to maintain health.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"4714077"},"PeriodicalIF":1.9,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11364472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feeding Behavior, Water Intake, and Physiological Parameters of Feedlot Lambs Fed with Diets Containing Babassu Oil Associated with Sunflower Oil Blend.","authors":"Laryssa V da Silva, Gleice Kelle S M Vilela, Karlyene S da Rocha, Hactus S Cavalcanti, Glayciane C Gois, Francisco Naysson de S Santos, Fleming S Campos, Michelle de O M Parente, Anderson de M Zanine, Daniele de J Ferreira, Tobyas M de A Mariz, Danielle de O Maia, Henrique N Parente","doi":"10.1155/2024/8673922","DOIUrl":"https://doi.org/10.1155/2024/8673922","url":null,"abstract":"<p><p>This study aimed to investigate the impact of dietary inclusion of babassu oil (BO) associated with sunflower oil (SO) on feeding behavior, water intake, and physiological parameters of feedlot lambs. Thirty-five castrated male lambs (16.6 kg ± 3.9 kg) were distributed in a randomized block design with 5 treatments (diets) and 7 replications. The tested diets were oil-free diet (OF), 45 g/kg BO (BO), 30 g/kg BO with an additional 15 g/kg SO (1.5 SO), 22.5 g/kg BO with an additional 22.5 g/kg SO (2.25 SO), and 30 g/kg SO with an additional 15 g/kg BO (3.0 SO) on dry matter (DM) basis. The experimental period lasted 60 days. Animals that received BO diet and the combination of BO with SO had lower intakes of DM and neutral detergent fiber (NDF) compared to the control diet (<i>P</i> < 0.05). Differences on the respiratory rate (RR) was observed between animals in the control diet and those in the diets containing SO (<i>P</i>=0.001), with a linear increase in RR as the levels of SO in the diets increased (<i>P</i>=0.004). All physiological parameters showed a time effect (<i>P</i> < 0.05). Animals fed with the control diet had higher water intake via drinking fountain (<i>P</i>=0.030) and total water intake (<i>P</i>=0.029) compared to animals fed with diets containing SO. In relation to SO levels, water intake via drinking fountain (<i>P</i>=0.002), total water intake (<i>P</i>=0.002), and total water intake per kg of DM ingested (<i>P</i>=0.001) linearly increased with the levels increase in the composition of the diets. The tested diets did not alter the feeding behavior of the feedlot lambs. However, the combination of BO with different levels of SO reduced DM and water intake via drinking fountain and RR.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"8673922"},"PeriodicalIF":1.9,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11390207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equine Trypanosomiasis: Molecular Detection, Hematological, and Oxidative Stress Profiling.","authors":"Mostafa Shoraba, Salma A Shoulah, Faysal Arnaout, Abdelfattah Selim","doi":"10.1155/2024/6550276","DOIUrl":"10.1155/2024/6550276","url":null,"abstract":"<p><p>Surra caused by <i>Trypanosoma evansi</i> (<i>T. evansi</i>) is widely distributed and has significant impact on equine sector and international trades. However, there are no available data about the genetic characterization of this parasite in horses in Egypt. So, the goal of this study was to study the molecular characterization of <i>T. evansi</i> in horses and determine the changes in hematological parameters and oxidative stress associated with <i>T. evansi</i> infection. A total of 12 horses were examined using PCR targeting RoTat 1.2 VSG gene, and we evaluated the changes in hematological and oxidative stress between infected and healthy animals. The results revealed a notable reduction in red blood cell (RBC), hematocrit (HCT), and hemoglobin (Hb) levels in the infected horses, as compared to the control healthy group. In contrast, the infected group showed a substantial increase in mean corpuscular hemoglobin concentration (MCHC), mean corpuscular hemoglobin (MCH), and mean corpuscular volume (MCV). In addition, the infected group exhibited monocytopenia, eosinopenia, and notable lymphocytopenia. Regarding oxidative stress profile, the infected horses showed decreased levels of glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), and antioxidant capacity (TAC) compared to the control group. Moreover, the PCR assay targeting RoTat 1.2 VSG gene revealed positive specific band (205 bp) in all examined samples for <i>T. evansi</i> and the phylogenetic analysis demonstrated that strain of this study is closely related to <i>T. evansi</i> isolate in horses from India (MT501210) while showed difference from sequences of other species. The results emphasize the changes in blood composition and the body's response to oxidative stress caused by <i>T. evansi</i> infection in horses.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"6550276"},"PeriodicalIF":1.9,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbreak Investigation, Isolation, and Molecular Characterization of Lumpy Skin Disease Virus in Cattle from North West Oromia Region, Ethiopia.","authors":"Workisa Chala, Kasaye Adamu, Hawa Mohammed, Getaw Deresse, Shimelis Tesfaye, Esayas Gelaye","doi":"10.1155/2024/6038724","DOIUrl":"10.1155/2024/6038724","url":null,"abstract":"<p><p>Lumpy skin disease (LSD) is an economically significant viral disease because of its high morbidity and high production loss. Vaccination of cattle using LSD vaccines is a more effective disease preventive and control strategy in endemic countries such as Ethiopia. Despite high vaccination coverage, there is an increasing number of field reports of the disease outbreaks. Thus, an observational study was designed to investigate disease, characterize the disease-causing agent, and isolate the virus from a local isolate for future vaccine development. Wera Jarso and Amuru districts in North West Oromia were chosen based on outbreak occurrence. For this study skin, 13 pooled biopsy samples were collected from affected cattle. In this outbreak investigation, the morbidity rate was 6.50%, the mortality rate was 0.50%, and the case fatality rate was 7.77%. The virus was isolated from all skin samples on both lamb testis and lamb kidney primary cells and confirmed to be LSDV using conventional and real-time PCR genotyping. Therefore, after each suspected LSD outbreak, a molecular test should be carried out to confirm the cause of the disease, targeting the previously suggested RPO30 or GPCR genes. Further studies targeting more regions and outbreaks, including full genome sequencing to check for genetic differences between the field viruses and vaccine strains, are recommended.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"6038724"},"PeriodicalIF":1.9,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Manifestation and Phylogenetic Analysis of Peste des Petits Ruminants in Local Iraqi Breed Sheep in Al-Diwaniyah Province.","authors":"Khalefa A Mansour, Muthanna H Hussain, Saad H Al-Husseiny, Asaad J Abid, Qassim H Kshash","doi":"10.1155/2024/5579913","DOIUrl":"10.1155/2024/5579913","url":null,"abstract":"<p><p>Peste des petits ruminants (PPR), a contagious virus that infects sheep and goats, damages livestock globally. This study examined the clinical features and phylogenetic analysis of the PPR virus in Iraqi breed sheep from Al-Diwaniyah province. A clinical trial of 610 sheep from different flocks found 150 oral lesions. Special primers for RT-PCR and Mega11 for phylogenetic analysis were used to study the PPR virus nucleoprotein (N) gene. The PPR infection rate was 44.6% in 4-12 month olds (<i>n</i> = 33/131) and 4.8% in 36-48 month olds (<i>n</i> = 3/75). A 608-bp PPR virus partial N gene sequence was found in 49.3% of samples by RT-PCR. In leucine, isoleucine, proline, glycine, alanine, glutamine, asparagine, threonine, serine, arginine, and lysine codons, 25 amino acid alterations were found. The protein codon 56 alanine-valine alteration was most significant. Moving from a smaller hydrophobic amino acid to one with a bigger side chain may reduce protein stability. Steric hindrance or protein shape change from Valine's extended side chain may impact folding, stability, functionality, and interactions with other molecules. Furthermore, phylogenetic analysis showed that the Nigerian strain (MN271586) was most similar to our Iraqi strain, with 100% identity and coverage. This study found the Peste des Petits Ruminants (PPR) virus in sheep flocks in Al-Diwaniyah Governorate, Iraq, which is genetically similar to neighboring countries. PPR virus strains must be monitored and genetically characterized since N gene alterations can affect infection and propagation.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"5579913"},"PeriodicalIF":1.9,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11321894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Macleaya</i> Extract versus Pregabalin Therapeutic Effectiveness for Neuropathic Pain in Dogs.","authors":"Saowanee Petchnamthong, Titiyaporn Krambunlue, Nirut Suwanna","doi":"10.1155/2024/9939754","DOIUrl":"10.1155/2024/9939754","url":null,"abstract":"<p><p>Dogs suffer from neuropathic pain due to several neurological disorders, particularly intervertebral disc disease. We aimed to identify alternative therapeutics for neuropathic pain relief in dogs by comparing the treatment efficacy of pregabalin and <i>Macleaya</i> extract against neuropathic pain from cervical spinal hyperesthesia caused by intervertebral disc disease in dogs. We evaluated 10 dogs suffering from cervical intervertebral disc disease for neuropathic pain using the filament von Frey aesthesiometer (VFA). The dogs were randomly divided into two groups, G1 (<i>n</i> = 5) was treated with 4 mg/kg of pregabalin/12 hours orally for 14 days, and G2 (<i>n</i> = 5) was treated with 15 mg/kg <i>Macleaya</i> extract once daily orally for 14 days. To detect neuropathic pain, the VFA was used to measure the sensory threshold (ST) on days 0, 7, and 14. The results revealed decreases in all ST outcomes with no significant differences between the groups on day 14 posttreatment, as well as a decrease in the severity of neurological disease in both groups on day 7 posttreatment. No significant differences were detected in hematological and biochemical profiles (alanine aminotransferase (ALT), alkaline phosphatase (ALP), serum creatinine (SCR), urea nitrogen (BUN), and total protein (TP)) in both groups between pre- and posttreatment were not significantly different. The <i>Macleaya</i> extract can reduce neuropathic pain in a similar pattern to pregabalin. <i>Macleaya</i> extract may be effective for the treatment of neuropathic pain in dogs with spinal hyperesthesia.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"9939754"},"PeriodicalIF":1.9,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11303047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practical Principles of Palliative Care in Veterinary Oncology: Alleviating the Suffering of the Animal, Owner, and Veterinarian.","authors":"Beatriz F Paz, Marília G P A Ferreira, Ketlyn R Martins, Lucas Uccella, Andrigo Barboza de Nardi","doi":"10.1155/2024/5565837","DOIUrl":"10.1155/2024/5565837","url":null,"abstract":"<p><strong>Background: </strong>Palliative care for pets is a developing area that encompasses animals with cancer and other chronic and degenerative diseases.</p><p><strong>Objectives: </strong>To elucidate the guiding principles of palliative care in veterinary oncology.</p><p><strong>Methods: </strong>This article was structured from an extensive literature review and addresses the growing need for improved palliative care in veterinary medicine. Methods of quality of life assessment in animals with cancer, owner education, and the importance of an interdisciplinary team approach are discussed.</p><p><strong>Results: </strong>Palliative care aims to improve the animal's quality of life, alleviating its physical, emotional, and social suffering. Through attentive communication, palliative care also seeks to alleviate owners suffering from the moment of diagnosis to mourning the patient's death.</p><p><strong>Conclusions: </strong>The importance of offering palliative care alongside anticancer techniques and treatments should not be underestimated and should ideally use a multidisciplinary team approach.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"5565837"},"PeriodicalIF":1.9,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11260215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Induced Ruminal Lactic Acidosis in Sheep Treated with Various Remedial Agents in Libo Kemkem Districts, Northwest Ethiopia.","authors":"Balemual Abebaw, Achenef Melaku, Shimelis Dagnachew","doi":"10.1155/2024/5595475","DOIUrl":"10.1155/2024/5595475","url":null,"abstract":"<p><strong>Background: </strong>Grain overload is a ruminant metabolic disorder associated with overingestion or a sudden change to rapidly fermentable concentrate feeds.</p><p><strong>Objective: </strong>A randomized clinical trial was carried out in Libo Kemkem districts to investigate vital signs, ruminal fluid, and hematological changes in sheep related to grain overload and to assess the treatment efficacy of various remedial agents in Farta sheep breeds.</p><p><strong>Methods: </strong>All sheep were selected by using the simple random process, and categorized into four groups of eight animals groups I, II, and III in which each sheep was given 80 g of wheat flour per kg of body weight then baking soda, Magnalax, and digestive powder were treated successively, but group IV was the negative control group.</p><p><strong>Results: </strong>The current clinical trial explained that all acidotic sheep had statistically significant (<i>p</i> < 0.0002) lower body temperature, rumen motility, protozoa activity, and ruminal fluid pH with 38.48 ± 0.20, 0.5 ± 0.89, 6 (75%), and 5.37 ± 0.34 mean value successively. Nevertheless, there were significant (<i>p</i> < 0.0059) increments in hematological variables including total red blood cell, total white blood cell, packed cell volume, and hemoglobin estimation with 14.05 ± 1.27, 12.71 ± 0.99, 40.78 ± 5.24, and 14.78 ± 1.83 mean value, respectively, before treatment in acidotic sheep. There were also vital sign increments including pulse rate, respiratory rate, skin turgor, and capillary refill time with 123.5 ± 27.1, 73.75 ± 12.71, 3 ± 1.78, and 3.37 ± 1.77 mean values, respectively, before medical treatment in acidotic sheep. Digestive powder was the first drug of choice, followed by Magnalax, and baking soda was ranked at the end based on clinical recovery.</p><p><strong>Conclusion: </strong>The treatment effectiveness illustrated that all treatments could cure the grain overload. Nevertheless, digestive powder is the drug of choice based on the clinical and systemic recovery of the sheep. In addition to this, sheep should be introduced gradually to concentrate rations over 2-3 weeks with a mixture of concentrate in the milled feed containing roughage.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"5595475"},"PeriodicalIF":1.9,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11257759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic Analysis of the Beef Cattle Digits Slaughtered after 114 Days of Confinement.","authors":"Wanessa Patrícia Rodrigues da Silva, Paulo José Bastos Queiroz, Paulo Henrique Jorge da Cunha, Antônio Dionísio Feitosa Noronha Filho, Emmanuel Arnhold, Juliano José de Resende Fernandes, Kaique de Souza Nascimento, Naida Cristina Borges","doi":"10.1155/2024/5512555","DOIUrl":"10.1155/2024/5512555","url":null,"abstract":"<p><p>Foot disorders are responsible for up to 5% of confinement losses. Identifying the cause of lameness and applying the correct treatment are crucial measures. The possibility of determining the probable origins of digital lesions, their extension, and assistance in cases in which it was not possible to reach a definitive clinical diagnosis demonstrates that the radiographic evaluation provides information of great importance on cattle digits. Thus, this study aimed to investigate possible radiographic changes in the hoof, bone structures, and soft tissues of the digits of Nelore bulls at the end of the confinement period. Regarding the main signs, 100% (<i>n</i> = 24) showed proliferation of enthesophytes and osteophytes and irregular contours, 62.5% (<i>n</i> = 15) enlargement of vascular channels, 37.5% (<i>n</i> = 9) osteolysis, 33.4% (<i>n</i> = 8) gas content in the white line region, 20.84% (<i>n</i> = 5) gas content in the dorsal lamina region, and 4.16% (<i>n</i> = 1) presented palisade periosteal reaction. Ten (41.7%) out of 24 (100%) animals evaluated at the end of the confinement presented lameness, three animals of score three, four animals of score two, and three animals of score one. The higher the score indicating the severity of the signs observed in the visual assessment of the radiographs, the higher the internal angle values (moderate correlation of 0.5 and <i>p</i> < 0.05). A higher prevalence of osteo-proliferative radiographic changes was identified at the end of the 114-day confinement period in the third phalanx of Nellore cattle even in animals that had no lameness.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"5512555"},"PeriodicalIF":1.9,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice of Thai Dairy Farmers on the Use of Antibiotics.","authors":"Niorn Ratanapob, Aksorn Saengtienchai, Theera Rukkwamsuk","doi":"10.1155/2024/5553760","DOIUrl":"10.1155/2024/5553760","url":null,"abstract":"<p><p>Antibiotics have been used regularly in dairy farms by veterinarians; however, they were also used occasionally by farmers without any veterinary prescriptions. Because knowledge, attitude, and practice are important for sustainable antibiotic use, the levels of these aspects among farmers and associated factors should be determined to improve antibiotic use in dairy farming. The study was carried out in 89 Thai dairy farmers, using a structured questionnaire. Data were analyzed using descriptive statistics. The questions were scored and the total scores were calculated for each aspect. Factors associated with knowledge, attitude, and practice scores were identified using the multivariate linear regression. The mean scores for knowledge, attitude, and practice were 62%, 86%, and 78%, respectively. Higher education, participation in a training related to antibiotic use, and being supervised by the Veterinary Teaching Hospital Nong Pho were associated with a higher knowledge score (<i>p</i> < 0.050). Farmers with less experience received a higher attitude score (<i>p</i> = 0.020). Acquiring antibiotic knowledge from other farmers was associated with a lower practice score (<i>p</i> = 0.005). A positive association was found between knowledge and attitude scores (<i>p</i> = 0.021) and practice and attitude score (<i>p</i> < 0.001). Due to the insufficient knowledge on antibiotic use, there is a need to fill the gap to ensure prudent antibiotic use by farmers. Recommendations including training farmers by veterinarian to perceive the prudent antibiotic uses, encouraging young generation with higher education to participate in dairy farming, providing antibiotic use protocols, and decreasing the availability of antibiotics should be implemented to limit overuse by farmers.</p>","PeriodicalId":23503,"journal":{"name":"Veterinary Medicine International","volume":"2024 ","pages":"5553760"},"PeriodicalIF":1.9,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}