Value in health regional issues最新文献

{"title":"Comment on “Savings Through Telemedicine”: Addressing Hidden Costs and Quality Concerns","authors":"Baifeng Zheng BS","doi":"10.1016/j.vhri.2025.101135","DOIUrl":"10.1016/j.vhri.2025.101135","url":null,"abstract":"","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"49 ","pages":"Article 101135"},"PeriodicalIF":1.4,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-Related Quality of Life in Patients With Alzheimer Disease in Malaysia: Evidence from EQ-5D and QOL-AD","authors":"Lyn Xuan Tay PhD ,&nbsp;Siew Chin Ong PhD ,&nbsp;Hui Ming Ong MRCP ,&nbsp;Ewe Eow Teh MMed ,&nbsp;Alan Swee Hock Ch’ng MMed ,&nbsp;Ing Khieng Tiong MRCP ,&nbsp;Rizah Mazzuin Razali MIntMed ,&nbsp;Thaigarajan Parumasivam PhD","doi":"10.1016/j.vhri.2025.101122","DOIUrl":"10.1016/j.vhri.2025.101122","url":null,"abstract":"<div><h3>Objectives</h3><div>There were only a few studies that assessed health-related quality of life (HRQoL) of patients with Alzheimer disease (AD) in Malaysia. This cross-sectional study was to investigate the HRQoL scores of patients with AD in Malaysia using 2 HRQoL instruments and to identify predictors of patients’ HRQoL.</div></div><div><h3>Methods</h3><div>Informal caregivers of patients with AD were recruited in 4 tertiary hospitals during outpatient visits. Patients’ HRQoL was assessed using proxy-rated generic (EQ-5D-5L and EQ-VAS), and disease-specific (Quality-of-life Alzheimer’s Disease [QoL-AD]) assessment instruments were utilized to obtain proxy HRQoL scores of patients with AD from caregivers via structured interviews. The difference between HRQoL scores and other variables was tested using analysis of variance. Pearson correlation test was conducted between the 2 instruments, whereas a multivariable linear regression model was utilized to identify predictors of HRQoL in patients with AD.</div></div><div><h3>Results</h3><div>The mean EQ-5D-5L index, EQ-VAS, and QoL-AD score of patients with AD were 0.63 ± 0.30, 61.05 ± 20.48, and 26.69 ± 6.83, respectively, via proxy ratings. In terms of correlation, EQ-5D was weakly correlated with QoL-AD (r = 0.36, <em>P</em> &lt; .01). EQ-5D index and QoL-AD score reduced significantly as AD advanced (<em>P</em> &lt; .05). Besides, cognitive decline, presence of behavioral symptoms, female caregiver gender, and nonmarried status were associated with lower patients’ HRQoL in multivariable models with EQ-5D index (<em>P</em> &lt; .05).</div></div><div><h3>Conclusions</h3><div>Low HRQoL of patients with AD requires attention from healthcare providers and stakeholders in optimal resource allocation and decision making. Such health utility values are useful in future economic evaluations in investigating the cost-effectiveness of new interventions or disease-modifying therapies.</div></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"48 ","pages":"Article 101122"},"PeriodicalIF":1.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Making the Investment Case for Mental Health in Low- and Middle-Income Countries","authors":"Dan Chisholm PhD ,&nbsp;Yong Yi Lee PhD ,&nbsp;Filip Meheus PhD ,&nbsp;Alexey Kulikov MD, PhD","doi":"10.1016/j.vhri.2025.101132","DOIUrl":"10.1016/j.vhri.2025.101132","url":null,"abstract":"","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"48 ","pages":"Article 101132"},"PeriodicalIF":1.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifetime Cost-Effectiveness of Using the Chinese Diabetes Risk Score for Prediabetes Screening in China","authors":"Song Li MB ,&nbsp;Jingjing Hao MSc ,&nbsp;Zhicheng Su MB ,&nbsp;Haichang Chen MB ,&nbsp;Zhaoyan Chen MSc ,&nbsp;Qiang Yao PhD ,&nbsp;Cairong Zhu PhD","doi":"10.1016/j.vhri.2025.101124","DOIUrl":"10.1016/j.vhri.2025.101124","url":null,"abstract":"<div><h3>Objectives</h3><div>To more comprehensively evaluate the lifetime cost-effectiveness of different prediabetes screening strategies based on the Chinese Diabetes Risk Score (CDRS) from a societal perspective and to explore the impact of different CDRS cutoff values on the evaluation.</div></div><div><h3>Methods</h3><div>A Markov model encompassing the complete natural history of type 2 diabetes was developed to compare costs, cumulative prevalence of type 2 diabetes complications, mortality rates, and quality-adjusted life years of 3 screening strategies: (1) the control group, the current screening strategy; (2) strategy 1, CDRS screening for all adults; and (3) strategy 2, supplemental CDRS screening for adults without annual health checkups. It was assumed that the individual exited the model upon reaching 80 years old or death in the model. The robustness of results was assessed through sensitivity analyses.</div></div><div><h3>Results</h3><div>Compared with the control group and strategy 2, strategy 1 saved $583.07 and $233.12 per capita, respectively, reduced the cumulative prevalence of type 2 diabetes complications by 8.47% and 1.64%, respectively, reduced mortality rates by 1.47% and 0.25%, respectively, and increased quality-adjusted life years by 0.07 and 0.01 per capita, respectively. At the cutoff value of 24, strategy 1 achieved the lowest cost and the highest health benefits.</div></div><div><h3>Conclusions</h3><div>Compared with the control group and strategy 2, strategy 1—implementing prediabetes screening in all adults via CDRS—was absolutely dominant when modeling the complete natural history of diabetes. The CDRS screening strategies demonstrated better cost-effectiveness when the cutoff value was set at 24.</div></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"49 ","pages":"Article 101124"},"PeriodicalIF":1.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Bangla Version of the HeartQoL Health-Related Quality-of-Life Questionnaire for Patients With Coronary Heart Disease in Bangladesh","authors":"Jamal Uddin MPH ,&nbsp;Sayed I. Alam MSc ,&nbsp;Graziella Zangger MSc ,&nbsp;Lau C. Thygesen PhD ,&nbsp;Md. Rezaul Karim MBBS ,&nbsp;Mohammad A. Rashid MPH ,&nbsp;Fazila-Tun-Nesa Malik MRCP ,&nbsp;Mir Ishraquzzaman MBBS ,&nbsp;Sheikh Mohammad M. Sobhan MPH ,&nbsp;Sohel R. Choudhury PhD ,&nbsp;Ann-Dorthe O. Zwisler MD, PhD ,&nbsp;Neil B. Oldridge PhD ,&nbsp;Rod S. Taylor PhD","doi":"10.1016/j.vhri.2025.101126","DOIUrl":"10.1016/j.vhri.2025.101126","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the psychometric properties of the Bangla version of the HeartQoL questionnaire, a core heart disease health-related quality-of-life (HRQoL) instrument, specifically in coronary heart disease (CHD) patients.</div></div><div><h3>Methods</h3><div>The English HeartQoL was translated into Bangla and then a cross-sectional and a test-retest study was undertaken in 2 specialized cardiac hospitals in Bangladesh. All patients admitted for percutaneous coronary intervention or coronary artery bypass graft between April and October 2019 and diagnosed with CHD were eligible for recruitment. The Bangla HeartQoL, EQ-5D-3L, PHQ-9, and GAD-7 questionnaires were administered before and after discharge. Factor structure, internal consistency, and construct validity of Bangla HeartQoL were assessed.</div></div><div><h3>Results</h3><div>A total of 945 patients with CHD were enrolled with a subgroup of 198 patients providing test-retest data. Mokken scale analysis supported the 2-factor structure (physical/mental subscales) of the HeartQoL Bangla questionnaire. Although no floor effects were observed, there was some evidence of a ceiling effect on the HeartQoL emotional subscale in 16.1% of patients. The Bangla HeartQoL questionnaire demonstrated satisfactory internal consistency (Cronbach’s alpha &gt; 0.75), discriminative validity (lower scores in patients with poorer health), and responsiveness to change (effect sizes of 0.23 to 0.68).</div></div><div><h3>Conclusions</h3><div>The Bangla HeartQoL questionnaire was found to be a valid, reliable, and responsive measure of HRQoL in CHD patients. However, future research is needed around its use, particularly in terms of its potential cultural sensitivity.</div></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"49 ","pages":"Article 101126"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethical and Statistical Issues in the Randomized Controlled Trial Assessing Cost-Effectiveness of Olanzapine Versus Aprepitant","authors":"Manraj Singh Sra MBBS","doi":"10.1016/j.vhri.2025.101133","DOIUrl":"10.1016/j.vhri.2025.101133","url":null,"abstract":"","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"48 ","pages":"Article 101133"},"PeriodicalIF":1.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Reply: Investment Case for Mental Health","authors":"Cyprian M. Mostert MSc, MM, MSP, PhD","doi":"10.1016/j.vhri.2025.101131","DOIUrl":"10.1016/j.vhri.2025.101131","url":null,"abstract":"","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"48 ","pages":"Article 101131"},"PeriodicalIF":1.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and Cross-Cultural Adaptation of Treatment Satisfaction Questionnaire for Medication Version 2 Among Older Adult Patients in Malaysia: A Psychometric Testing Study","authors":"Mohammad Adam Al Haqimy Mohammad Yunus MPharm ,&nbsp;Muhammad Eid Akkawi PhD","doi":"10.1016/j.vhri.2025.101128","DOIUrl":"10.1016/j.vhri.2025.101128","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess the full psychometric testing of the translated Malay version of Treatment Satisfaction Questionnaire for Medication version 2 (TSQM v.2).</div></div><div><h3>Methods</h3><div>This is a cross-sectional study involving a convenience sample of 429 older adult patients at outpatient settings of a teaching hospital in Malaysia. All patients answered the Malay version (M-TSQM v.2). The instrument reliability was tested using Cronbach’s alpha and composite reliability. Content validity was assessed by a panel of experts, whereas convergent validity was tested using the average variance extracted values. Confirmatory factor analysis was used to determine factorial validity and subsequently construct validity.</div></div><div><h3>Results</h3><div>Cronbach’s α for all the domains in the M-TSQM v.2 yielded a value above 0.7, and all domains exhibit a composite reliability value above 0.6, which indicate a good internal consistency. The confirmatory factor analysis of the 11 items in the 4 domains demonstrated acceptable factor loading (≥0.6), confirming the 4-factor dimensionality. The applied hierarchical confirmatory factor analysis proved that the model was good fit based on the absolute, incremental, and parsimonious fitness indices.</div></div><div><h3>Conclusions</h3><div>The M-TSQM v.2 is a valid, reliable, and psychometrically sound instrument for assessing treatment satisfaction among Malay-speaking populations. Therefore, it could be utilized crucially to capture the trueness level of treatment satisfaction in Malaysian patients regardless of their morbidity status, given that it is a generic measurement tool.</div></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"49 ","pages":"Article 101128"},"PeriodicalIF":1.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143931518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation of the Experimental Version of EQ-5D-Y-5L Into Bahasa Indonesia","authors":"Titi S. Fitriana PhD ,&nbsp;Fredrick D. Purba PhD ,&nbsp;Elly Stolk PhD ,&nbsp;Jan J.V. Busschbach PhD","doi":"10.1016/j.vhri.2025.101121","DOIUrl":"10.1016/j.vhri.2025.101121","url":null,"abstract":"<div><h3>Objectives</h3><div>The EQ-5D-Y-5L has been developed to provide an appropriate version of EQ-5D for children. This article reports the EQ-5D-Y-5L adaptation process into Bahasa Indonesia.</div></div><div><h3>Methods</h3><div>Forward and backward translations were performed to produce equal qualifiers between EQ-5D-Y-5L English and Bahasa versions. Unresolved issues were addressed in a cognitive debriefing, conducted with 10 children aged 8 to 15. A linguist proofread the final stage of the translation.</div></div><div><h3>Results</h3><div>Differences were found in wordings, headings, font styles, and qualifiers in EQ-5D English versions that require consideration when translating the English version into other languages. Two issues arose: first, levels 1, 2, and 4 in EQ-5D-Y-5L Bahasa matched the levels 1, 2, and 3 of EQ-5D-Y-3L, rather than levels 1, 3, and 4, as is the case in the English versions. Second, the translated words for “pain” and “worried,” used in the other EQ-5D Bahasa, were difficult to comprehend. Hence, we replaced these words with alternative Bahasa words at the cost of breaking consistency between the EQ-5D-Y-3L and EQ-5D-Y-5L Bahasa. There was an indication that the extensive cognitive debriefing caused response fatigue in children.</div></div><div><h3>Conclusions</h3><div>The adaptation process resulted in a comprehensible EQ-5D-Y-5L Bahasa Indonesia for children aged 8 to 16. Our findings suggest a need to review the existing EQ-5D-Y-3L and EQ-5D-3L in Bahasa Indonesia. While awaiting this review, research related to these 2 measures should be interpreted with caution in the context of international comparisons. Furthermore, we propose consideration of a more user-friendly approach to cognitive debriefing tailored for children.</div></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"49 ","pages":"Article 101121"},"PeriodicalIF":1.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare Costs of Myocardial Infarction in Denmark: A Nation-Wide Registry-Based Cohort Study","authors":"Kristoffer Jarlov Jensen PhD ,&nbsp;Jedidiah I. Morton PhD ,&nbsp;Marius Mølsted Flege MD ,&nbsp;Janne Petersen PhD ,&nbsp;Zanfina Ademi PhD","doi":"10.1016/j.vhri.2025.101125","DOIUrl":"10.1016/j.vhri.2025.101125","url":null,"abstract":"<div><h3>Objectives</h3><div>Myocardial infarction (MI) is highly detrimental and healthcare intensive with a high incidence globally. This study aimed to estimate the individual healthcare costs of MI in Denmark from a public health provider perspective.</div></div><div><h3>Methods</h3><div>In this nation-wide registry-based cohort study, individuals with incident MI between 2012 and 2016 were propensity score-matched 1:3 with non-MI controls. Excess costs were calculated as costs of patients with MI minus average costs of matched controls, accounting for all individual-level hospital contacts and treatment, primary care, and reimbursed prescription medicine, analyzed as acute or long-term costs in 6-month intervals during 4 years before and 4 years after the MI event. For acute costs and the first 6 months, data were available to extend the cohort period to include index year 2019.</div></div><div><h3>Results</h3><div>In total, 34 310 individuals with a first-time MI were matched to non-MI controls. The mean total acute healthcare cost of first-time MI was €11 462 (95% confidence interval: 11 313-11 612), and cost was €5966 (5788-6145) during the first 6 months, decreasing to €1696 (1565-1827) during the next 6 months. Females with MI incurred 26% lower acute costs and 20% lower excess costs during the first 6 months than males did but higher excess costs than males past 1 year. Costs were highest in people aged 60 to 79 and gradually decreased over the later study years.</div></div><div><h3>Conclusions</h3><div>We found that MI is associated with significant acute and long-term health care costs. With constant or slightly decreasing healthcare expenses on a background of a general decline in MI incidence rates, the total healthcare spendings on MI may decline in the years ahead.</div></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"48 ","pages":"Article 101125"},"PeriodicalIF":1.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}