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Vagus nerve stimulation for the treatment of treatment-refractory epilepsy 迷走神经刺激治疗难治性癫痫
Ugeskrift for laeger Pub Date : 2024-06-03 DOI: 10.61409/v10230638
Per Jensen, Ioannis Tsiropoulos
{"title":"Vagus nerve stimulation for the treatment of treatment-refractory epilepsy","authors":"Per Jensen, Ioannis Tsiropoulos","doi":"10.61409/v10230638","DOIUrl":"https://doi.org/10.61409/v10230638","url":null,"abstract":"About 40 % of new-onset epilepsy is drug refractory. If epilepsy surgery is not an option or fails, vagal nerve stimulation (VNS) can be considered. VNS efficacy is reported as more than 50 % seizure frequency reduction in 50-56 % of patients. Features in the newer models offer additional treatment optimization possibilities. Side effects include hoarseness, cough, and dyspnoea. Caution is advised for patients with sleep apnoea or lung disease. VNS has specific limitations concerning MRI. This review presents an overview of VNS treatment in Denmark and discusses future challenges.","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141388765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eczema herpeticum 疱疹性湿疹
Ugeskrift for laeger Pub Date : 2024-06-03 DOI: 10.61409/v72041
Anne Sofie Frølunde, Mette Sommerlund
{"title":"Eczema herpeticum","authors":"Anne Sofie Frølunde, Mette Sommerlund","doi":"10.61409/v72041","DOIUrl":"https://doi.org/10.61409/v72041","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141388540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment of right-sided colon cancer with complete mesocolic excision 右侧结肠癌的手术治疗：结肠系膜完全切除术
Ugeskrift for laeger Pub Date : 2024-06-03 DOI: 10.61409/v11230742
Celine Lindqvist Neergaard, Pedja Cuk, I. Al-Najami, M. Ellebæk
{"title":"Surgical treatment of right-sided colon cancer with complete mesocolic excision","authors":"Celine Lindqvist Neergaard, Pedja Cuk, I. Al-Najami, M. Ellebæk","doi":"10.61409/v11230742","DOIUrl":"https://doi.org/10.61409/v11230742","url":null,"abstract":"Complete mesocolic excision for right-sided colon cancer yields larger specimens with higher lymph node harvest. This has caused a reduction in recurrence rates and improved survival. However, the technique remains controversial and has been associated with a higher risk of intraoperative complications. More recently published studies do not indicate that CME is associated with increased postoperative morbidity rates as summarised in this review. More detailed consensus regarding the use of the technique is needed, and future studies should aim for prospective confirmation of the current positive long-term results.","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141388442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P. aeruginosa infection of the ulna, a rare complication after arterial puncture 动脉穿刺后的罕见并发症--尺骨铜绿假单胞菌感染
Ugeskrift for laeger Pub Date : 2024-06-03 DOI: 10.61409/v01240062
Daniel Bomark, Jesper Fabrin, M. S. Sørensen
{"title":"P. aeruginosa infection of the ulna, a rare complication after arterial puncture","authors":"Daniel Bomark, Jesper Fabrin, M. S. Sørensen","doi":"10.61409/v01240062","DOIUrl":"https://doi.org/10.61409/v01240062","url":null,"abstract":"Pseudomonas aeruginosa, a Gram-negative bacterium known to induce severe infections, is seldomly reported in scientific literature as a contributor of osteomyelitis. In this case report, a 71-year-old woman exhibited recurring infections and enduring forearm pain. A subsequent MRI revealed osteomyelitis in the distal ulna, linked to an arterial blood gas sample taken months earlier. Despite undergoing multiple extended courses of antibiotic treatment, the patient eventually underwent surgery on her left forearm. Biopsy cultures conclusively confirmed the presence of P. aeruginosa.","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141388332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Criteria for brain death in Denmark. 丹麦的脑死亡标准。
Ugeskrift for laeger Pub Date : 2024-05-27 DOI: 10.61409/V11230695
Jesper Kelsen, Karen Irgens Tanderup Hansen, Andreas Hjelm Brandt, Peter Birkeland, Marwan H Othman, Trine Stavngaard, Niels Agerlin, Daniel Kondziella
{"title":"Criteria for brain death in Denmark.","authors":"Jesper Kelsen, Karen Irgens Tanderup Hansen, Andreas Hjelm Brandt, Peter Birkeland, Marwan H Othman, Trine Stavngaard, Niels Agerlin, Daniel Kondziella","doi":"10.61409/V11230695","DOIUrl":"10.61409/V11230695","url":null,"abstract":"<p><p>In 1990, the Danish brain death legislation was adopted by the Danish Parliament. Each year, around 100 patients in Denmark fulfil criteria for brain death/death by neurological criteria (BD/DNC). In this review of current Danish criteria including the indication for ancillary investigation, which in Denmark is digital subtraction angiography (DSA), we conclude that the time has come to revise the national BD/DNC criteria. We propose that visible anoxic-ischaemic encephalopathy on brain CT after cardiac arrest does not require evaluation by ancillary testing, and that CT-angiography can be used instead of DSA.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ECMO ved hjerte- og/eller lungesvigt. 心衰和/或肺衰患者的 ECMO。
Ugeskrift for laeger Pub Date : 2024-05-27 DOI: 10.61409/V205169
Jakob Gjedsted, Steffen Christensen, Hasse Møller-Sørensen
{"title":"ECMO ved hjerte- og/eller lungesvigt.","authors":"Jakob Gjedsted, Steffen Christensen, Hasse Møller-Sørensen","doi":"10.61409/V205169","DOIUrl":"https://doi.org/10.61409/V205169","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Life-threatening vaginal bleeding after starting rivaroxaban treatment. 开始利伐沙班治疗后出现危及生命的阴道出血。
Ugeskrift for laeger Pub Date : 2024-05-27 DOI: 10.61409/V01240012
Luna Fabricius Ekenberg, Line Markdanner Lindgren, Caroline Pehrson
{"title":"Life-threatening vaginal bleeding after starting rivaroxaban treatment.","authors":"Luna Fabricius Ekenberg, Line Markdanner Lindgren, Caroline Pehrson","doi":"10.61409/V01240012","DOIUrl":"10.61409/V01240012","url":null,"abstract":"<p><p>This is a case report of a 44-year-old premenopausal woman who was admitted to hospital due to uncontrollable and life-threatening vaginal bleeding after starting rivaroxaban treatment for atrial fibrillation. She had a medical history with menorrhagia due to an intrauterine fibroma. She did not respond sufficiently to factor X supplement or other non-surgical medical interventions. The bleeding subsided after bilateral embolization of aa. uterinae.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin B12 deficiency. 维生素 B12 缺乏症。
Ugeskrift for laeger Pub Date : 2024-05-27 DOI: 10.61409/V01240008
Emil Buhl, Bettina Borre Buhl, Linda Skibsted Kornerup, Ebba Nexø
{"title":"Vitamin B12 deficiency.","authors":"Emil Buhl, Bettina Borre Buhl, Linda Skibsted Kornerup, Ebba Nexø","doi":"10.61409/V01240008","DOIUrl":"10.61409/V01240008","url":null,"abstract":"<p><p>No international treatment standard for B12 deficiency exists. Current practice predominantly relies on more than 50 years old data. Consequently, this review investigates that we still recommend five injections with 1 mg B12 over 10 days followed by maintenance therapy with 1 mg oral B12 daily or injections, of which the interval is guided by symptom relief rather than normalization of biomarkers. Clinical studies are highly warranted and should include formulation and administration of B12. Subcutaneous self-injection may prove cost-effective and benefit an individualized treatment strategy.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute pancreatitis in an ulcerative colitis patient treated with vedolizumab and budesonide. 一名溃疡性结肠炎患者在接受韦多珠单抗和布地奈德治疗后出现急性胰腺炎。
Ugeskrift for laeger Pub Date : 2024-05-27 DOI: 10.61409/V01240025
Christel Dupont Ravn, Mia Bendix, Søren Lyhne
{"title":"Acute pancreatitis in an ulcerative colitis patient treated with vedolizumab and budesonide.","authors":"Christel Dupont Ravn, Mia Bendix, Søren Lyhne","doi":"10.61409/V01240025","DOIUrl":"10.61409/V01240025","url":null,"abstract":"<p><p>Acute pancreatitis (AP) is a sudden inflammation of the pancreas which often manifests as a mild disease but can be associated with high morbidity and mortality. Drug-induced AP is rare and most likely underdiagnosed. Vedolizumab is a human monoclonal antibody with gut-selective integrin antagonist effect, and it is used for treatment of inflammatory bowel disease (IBD). Budesonid is a glucocorticoid which is released in the colon and it is also used in IBD treatment. This is a case report where vedolizumab or budesonide caused acute pancreatitis in a young man with ulcerative colitis.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kirurgisk håndtering af invasive kondylomer i anogenitalområdet. 肛门生殖器部位浸润性尖锐湿疣的手术治疗。
Ugeskrift for laeger Pub Date : 2024-05-20 DOI: 10.61409/V72029
Cecilie Jansen, Sakshi Andersen, Mikkel Rosendahl, Alessandro Venzo
{"title":"Kirurgisk håndtering af invasive kondylomer i anogenitalområdet.","authors":"Cecilie Jansen, Sakshi Andersen, Mikkel Rosendahl, Alessandro Venzo","doi":"10.61409/V72029","DOIUrl":"https://doi.org/10.61409/V72029","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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