维生素 B12 缺乏症。

Q4 Medicine

Ugeskrift for laeger Pub Date : 2024-05-27 DOI:10.61409/V01240008

Emil Buhl, Bettina Borre Buhl, Linda Skibsted Kornerup, Ebba Nexø

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引用次数: 0

摘要

目前还没有针对 B12 缺乏症的国际治疗标准。目前的做法主要依赖于 50 多年前的数据。因此，本综述调查发现，我们仍建议在 10 天内注射 5 次 1 毫克 B12，然后每天口服或注射 1 毫克 B12，以维持治疗。临床研究十分必要，应包括 B12 的配方和给药。皮下自我注射可能会被证明具有成本效益，并有利于个体化治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vitamin B12 deficiency.

No international treatment standard for B12 deficiency exists. Current practice predominantly relies on more than 50 years old data. Consequently, this review investigates that we still recommend five injections with 1 mg B12 over 10 days followed by maintenance therapy with 1 mg oral B12 daily or injections, of which the interval is guided by symptom relief rather than normalization of biomarkers. Clinical studies are highly warranted and should include formulation and administration of B12. Subcutaneous self-injection may prove cost-effective and benefit an individualized treatment strategy.

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来源期刊

Ugeskrift for laeger Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

345

期刊介绍： The Ulster Medical Journal is an international general medical journal with contributions on all areas of medical and surgical specialties relevant to a general medical readership. It retains a focus on material relevant to the health of the Northern Ireland population. The Honorary Editor would welcome offers of papers for publication. Prospective authors are invited to read the notice to contributors.