UrologyPub Date : 2025-06-18DOI: 10.1016/j.urology.2025.06.033
David Bayne
{"title":"Editorial Comment on \"Systematic Review on the Learning Curve of Percutaneous Nephrolithotomy: Operative Time, Fluoroscopy Time, Stone-free Rate, Puncture Performance, Complications, and Safety Indicators\".","authors":"David Bayne","doi":"10.1016/j.urology.2025.06.033","DOIUrl":"10.1016/j.urology.2025.06.033","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-16DOI: 10.1016/j.urology.2025.06.027
Anuja Thakur, Lalit Kumar
{"title":"Reply to Letter to the Editor on \"A Comparison Between Intravesical Gemcitabine Plus Docetaxel and Intravesical Bacillus Calmette-Guérin in the Treatment of Nonmuscle Invasive Naive Urinary Bladder Cancer: A Systematic Review and Meta-Analysis of Oncological Outcomes\".","authors":"Anuja Thakur, Lalit Kumar","doi":"10.1016/j.urology.2025.06.027","DOIUrl":"10.1016/j.urology.2025.06.027","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-16DOI: 10.1016/j.urology.2025.06.019
Abdul-Jawad J Majeed, Dennis Head, Jay D Raman
{"title":"Reply to Letter to the Editor on \"Electronic Residency Application Service Application Fees in Surgical Subspecialties: A Barrier to a Diverse Healthcare Workforce?\"","authors":"Abdul-Jawad J Majeed, Dennis Head, Jay D Raman","doi":"10.1016/j.urology.2025.06.019","DOIUrl":"10.1016/j.urology.2025.06.019","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-16DOI: 10.1016/j.urology.2025.06.032
Campbell Grant
{"title":"Editorial Comment on \"Analyzing the Patterns of Industry Payments in Urology: A Benchmark Comparison With Other Surgical Specialties\".","authors":"Campbell Grant","doi":"10.1016/j.urology.2025.06.032","DOIUrl":"10.1016/j.urology.2025.06.032","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-16DOI: 10.1016/j.urology.2025.06.028
Nicholas Choi, Bristol B Whiles
{"title":"Editorial Comment on \"Prediction of Retrograde Intrarenal Surgery Outcomes in Patients With Horseshoe Kidneys Using Three Different Scoring Systems: A Critical Single-center Experience\".","authors":"Nicholas Choi, Bristol B Whiles","doi":"10.1016/j.urology.2025.06.028","DOIUrl":"10.1016/j.urology.2025.06.028","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-15DOI: 10.1016/j.urology.2025.06.026
Bridget L Findlay, Anthony Fadel, Miriam Dash, Jayson Kemble, Boyd R Viers, Katherine T Anderson
{"title":"Long-term Trends in Bladder Management Strategies in Females Following Spinal Cord Injury.","authors":"Bridget L Findlay, Anthony Fadel, Miriam Dash, Jayson Kemble, Boyd R Viers, Katherine T Anderson","doi":"10.1016/j.urology.2025.06.026","DOIUrl":"10.1016/j.urology.2025.06.026","url":null,"abstract":"<p><strong>Objective: </strong>To describe trends in bladder management strategies (BMS) for female patients following spinal cord injury (SCI).</p><p><strong>Methods: </strong>Data were collected from the National Spinal Cord Injury Model Systems Database on 29,202 patients from 1972 to 2016. BMS included the following categories: Noninvasive (N), Urinary Diversion (UD), Urethral Catheter (UC), Intermittent Catheterization (CIC), and suprapubic catheter. Descriptive statistics were summarized, and chi-squared analysis with Bonferroni correction was used to compare BMS among males and females.</p><p><strong>Results: </strong>The most common BMS for females at 40 years follow up was UC (33%), followed by CIC (30%) and N (22%). The proportion of UD increased from approximately 0% initially to 7% at 40 years. At any timepoint, females were significantly more likely to have UD (2.2% vs 1.2%) and UC (24.3% vs 12.4%) compared to males but less likely to perform CIC (38.3% vs 32.8%) or use an Suprapubic Catheter (18.5% vs 9.1%) (all P <.05). Patient-reported wheelchair use was prevalent among females with UD (94%), with 67% of them reporting new wheelchair use at the time of conversion to UD.</p><p><strong>Conclusion: </strong>The use of UC in females after SCI is commonplace despite the known risks of this BMS. UD increase over time, which may be due to complications from previous BMS or functional decline, such as transition to wheelchair use. Further studies are needed to better understand the factors that govern the choice of each BMS and the associated effect on quality of life.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-15DOI: 10.1016/j.urology.2025.06.030
Matthew S Lee, Marco Moschini, Cameron J Britton, Mattia Longoni, Robert F Tarrell, Austin J Martin, Bryan J Traughber, Bradley J Stish, Jacob J Orme, Paras H Shah, Igor Frank, R Jeffrey Karnes, Stephen A Boorjian, Vidit Sharma
{"title":"Development and External Validation of a Local Pelvic Recurrence Risk Score After Radical Cystectomy: Identifying the Ideal Candidate for Adjuvant Radiation Clinical Trials.","authors":"Matthew S Lee, Marco Moschini, Cameron J Britton, Mattia Longoni, Robert F Tarrell, Austin J Martin, Bryan J Traughber, Bradley J Stish, Jacob J Orme, Paras H Shah, Igor Frank, R Jeffrey Karnes, Stephen A Boorjian, Vidit Sharma","doi":"10.1016/j.urology.2025.06.030","DOIUrl":"10.1016/j.urology.2025.06.030","url":null,"abstract":"<p><strong>Objective: </strong>To develop a risk stratification tool for locoregional recurrence (LR) after radical cystectomy (RC). LR confers a poor prognosis and current risk stratification tools are lacking, representing a critical knowledge gap in facilitating trial design for adjuvant local therapy.</p><p><strong>Methods: </strong>We reviewed our institutional Cystectomy Registry to identify factors associated with LR. A risk score was created using the multivariable regression coefficients.</p><p><strong>Results: </strong>Among 1256 patients who underwent RC, 227 experienced LR, with median time to LR of 11 months, resulting in a 2- and 5-year LR risk of 17% and 22%, respectively. Median follow-up was 4.4 years after LR. On multivariable analysis, pT-stage (HR=1.72), pN+ (HR=1.90), and number of lymph nodes removed (HR=0.98 per node) were independently associated with LR (all P<.01). Positive ureteral/urethral margin (HR=1.52) and positive radial margin (HR=1.58) were associated with LR with P=.08 and P=.07, respectively. Our risk score stratified patients by risk of 5-year LR from 2% to 52% with c-index of 0.73. External validation in a European cystectomy cohort (N=614) demonstrated comparable performance to the development cohort with c-index of 0.75 at 3 years.</p><p><strong>Conclusion: </strong>We developed a risk score based on post-cystectomy pathologic variables, which effectively stratified patients' risk of subsequent LR. The risk score had similar performance in the internal development and external validation cohorts, despite the cohorts being geographically distinct with different LR event rates. This risk score may therefore be considered in designing adjuvant therapy trials (eg, radiation, immunotherapy) for high-risk patients after RC.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-14DOI: 10.1016/j.urology.2025.06.024
Gwen M Grimsby
{"title":"Editorial Comment on \"Characterization of Female Urologists' Pregnancy, Perinatal and Breastfeeding Outcomes\".","authors":"Gwen M Grimsby","doi":"10.1016/j.urology.2025.06.024","DOIUrl":"10.1016/j.urology.2025.06.024","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-06-14DOI: 10.1016/j.urology.2025.06.029
Daniel J Kim, Patrick E Teloken, John P Mulhall
{"title":"Exploring the Association Between Varicocele and Testosterone Deficiency in Men Over 50 Years of Age.","authors":"Daniel J Kim, Patrick E Teloken, John P Mulhall","doi":"10.1016/j.urology.2025.06.029","DOIUrl":"10.1016/j.urology.2025.06.029","url":null,"abstract":"<p><strong>Objective: </strong>To define the impact of varicoceles (VX) on total testosterone (TT) levels in an aging male population.</p><p><strong>Methods: </strong>This retrospective analysis of a departmental database assessed patients ≥50 years of age, who had 2 testes, and recorded early morning TT levels. Patient demographics, comorbidity profiles, VX laterality, and VX grade were also analyzed.</p><p><strong>Results: </strong>Data were retrievable for 776 patients. Mean age was 66±12years. Around 140 (18%) patients had at least 1 VX on examination (VX+). Of these 118 (84%) had unilateral VX while 22 (16%) had bilateral. Mean TT for the VX+ group (336ng/dL±168) was statistically significantly lower than for the VX- group (472ng/dL ±267) (P<.01). Those with bilateral VX had lower TT (297ng/dL) than those with unilateral VX (372ng/dL) (P<.05). While 16% of the total VX+ population had TT levels <300ng/dl, these rates were 11% and 24% in men with unilateral and bilateral VX (P<.01). In those with unilateral VX, there was a relationship between VX grade and testosterone deficiency, with the highest likelihood associated with Grade III (r=0.65, P<.01). There was no association between Grade I and low T levels.</p><p><strong>Conclusion: </strong>In this population of men older than 50, the presence, laterality, and grade of VX were associated with lower levels of TT.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}