UrologyPub Date : 2025-07-11DOI: 10.1016/j.urology.2025.07.009
Tuan Thanh Nguyen, Adnan El-Achkar, Ho Yee Tiong, Ryan W Dobbs, Jad Najdi, Narmina Khanmammadova Onder, Ngoc Sinh Tran, Huy Gia Vuong, Jacob Basilius, Xuan Thai Ngo, Van Dinh Le Quy, Trong Hieu Le, Tien-Dat Hoang, Khoa Quy, Minh Sam Thai, Muhammed A Hammad, Se Young Choi, Sohrab Naushad Ali, Mohammed Shahait, Hung Phan Huu, David I Lee
{"title":"Robotic-Assisted vs. Open Kidney Transplantation: A Systematic Review and Meta-Analysis of Propensity-Matched Studies.","authors":"Tuan Thanh Nguyen, Adnan El-Achkar, Ho Yee Tiong, Ryan W Dobbs, Jad Najdi, Narmina Khanmammadova Onder, Ngoc Sinh Tran, Huy Gia Vuong, Jacob Basilius, Xuan Thai Ngo, Van Dinh Le Quy, Trong Hieu Le, Tien-Dat Hoang, Khoa Quy, Minh Sam Thai, Muhammed A Hammad, Se Young Choi, Sohrab Naushad Ali, Mohammed Shahait, Hung Phan Huu, David I Lee","doi":"10.1016/j.urology.2025.07.009","DOIUrl":"https://doi.org/10.1016/j.urology.2025.07.009","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the perioperative and follow-up outcomes between robot-assisted kidney transplantation (RAKT) and open kidney transplantation (OKT).</p><p><strong>Methods: </strong>This systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered in PROSPERO (CRD42022334583).</p><p><strong>Results: </strong>Seven studies met the inclusion criteria, comprising a total of 1,263 kidney transplant cases (517 RAKT and 919 OKT). Compared to OKT, the RAKT group had shorter incision length (SMD = -9.00, p < 0.001), fewer overall postoperative complications (RR = 0.52, p = 0.024), and reduced Clavien-Dindo III-IV complications (RR = 0.58, p = 0.013). However, RAKT was associated with significantly longer warm ischemia time (SMD = 0.66, p < 0.001), cold ischemia time (SMD = 0.96, p = 0.011), rewarming time (SMD = 3.08, p = 0.053), and total ischemia time (SMD = 1.73, p = 0.054). No significant differences were observed in intraoperative complications (RR = 1.09, p = 0.898), delayed graft function (RR = 0.90, p = 0.750), reoperation rates (RR = 0.63, p = 0.354), or recipient survival at 1 year (RR = 1.00, p = 0.233). Graft survival at 1 year was slightly higher in the RAKT group (RR = 1.01, p = 0.031), with adjusted 1-year graft survival showing a significant advantage (RR = 1.03, p = 0.001).</p><p><strong>Conclusions: </strong>Despite perioperative benefits, RAKT does not demonstrate superior long-term graft survival or patient outcomes compared to OKT. Its adoption remains limited to specialized centers, and further high-quality studies are needed to clarify its clinical and economic impact.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-11DOI: 10.1016/j.urology.2025.07.010
Kadir Can Sahin, Selahattin Sutcuoglu, Hulya Rusan Zara, Cenk Ozcan, Mustafa Emre Bakircioglu
{"title":"Cryptozoospermia in the Shadow of Azoospermia: Accurate Diagnosis with Clinical Predictors and Extended Semen Analysis.","authors":"Kadir Can Sahin, Selahattin Sutcuoglu, Hulya Rusan Zara, Cenk Ozcan, Mustafa Emre Bakircioglu","doi":"10.1016/j.urology.2025.07.010","DOIUrl":"https://doi.org/10.1016/j.urology.2025.07.010","url":null,"abstract":"<p><strong>Objectives: </strong>To address the critical issue of cryptozoospermia misclassification as non-obstructive azoospermia (NOA), this study aims to highlight the importance of accurate cryptozoospermia diagnosis with extended semen analysis and to identify predictive clinical markers in men initially labeled as azoospermic.</p><p><strong>Methods: </strong>We retrospectively analyzed men diagnosed with azoospermia at external centers who underwent extended semen analysis at our center between April 2021-April 2024. To investigate the clinical significance and potential predictors, clinical data were compared to 239 patients diagnosed with NOA who underwent micro-TESE during the same period.</p><p><strong>Results: </strong>Extended semen analysis revealed cryptozoospermia in 74 of 372 patients (19.9%). Compared to the NOA group, patients with cryptozoospermia exhibited significantly lower FSH levels (p<0.001), higher total testosterone levels (p=0.002), larger testicular volumes (p<0.001), and a higher prevalence of AZFc microdeletions and parental consanguinity (p=0.029 and p=0.043, respectively). Multivariate analysis identified serum FSH level (<18.6 mIU/mL) and testicular volume (>11 mL) were found as independent predictors for the diagnosis of cryptozoospermia.</p><p><strong>Conclusion: </strong>Our findings reveal that nearly one in five men initially diagnosed with NOA were, in fact, reclassified as having cryptozoospermia following extended analysis. Clinicians should maintain a high index of suspicion for missed cryptozoospermia in azoospermic patients presenting with favorable clinical profiles-particularly lower FSH, higher testosterone, and larger testicular volume- to ensure accurate diagnosis and guide individualized ART strategies.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-11DOI: 10.1016/j.urology.2025.07.007
Ellen M Cahill, Ernesto Morfin Montes de Oca, Jose M Flores, Nelson E Bennett, John P Mulhall
{"title":"Knowledge and Attitudes towards Fertility Preservation in Patients undergoing Radical Prostatectomy.","authors":"Ellen M Cahill, Ernesto Morfin Montes de Oca, Jose M Flores, Nelson E Bennett, John P Mulhall","doi":"10.1016/j.urology.2025.07.007","DOIUrl":"https://doi.org/10.1016/j.urology.2025.07.007","url":null,"abstract":"<p><strong>Objective: </strong>To better understand the fertility discussion experience and attitudes regarding fertility of men undergoing radical prostatectomy (RP).</p><p><strong>Methods: </strong>Men who had had a RP within the prior 3 months who were ≤50 years of age with a partner of reproductive age (≤45 years) were included. In a written questionnaire, men were asked about their understanding of the impact of RP on their future fertility, whether they were counseled on sperm banking, whether they actually banked sperm, and if they had not, their level of interest in sperm extraction post-RP. Patient and partner demographic data was recorded. A multivariable model was constructed to look for predictors of interest in fertility in men undergoing RP.</p><p><strong>Results: </strong>In total, 364 men responded to the questionnaire. Median patient and partner age were 45 (39,49) and 35 (34,40) years, respectively. 28% of men indicated an interest in future fertility. 58% of men did not recall being told about anejaculation post-RP, 84% were unaware that sperm banking preoperatively was an option, and only 7% of those interested in fertility actually banked sperm. Only 8 men (2%) were aware that testis sperm extraction was a possibility post-RP. Predictors of interest in fertility post-RP included younger partner age, patient without children, and partner without children.</p><p><strong>Conclusion: </strong>While the majority of men undergoing RP are not interested in fertility, a distinct minority are, and appear to be poorly educated and prepared for fertility decisions before or after RP.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-10DOI: 10.1016/j.urology.2025.06.054
Anthony Galvez, Paige Kuhlmann, Margot Barker, Andrew Chen, Victoria Scott, Karyn Eilber, Jennifer Anger
{"title":"Association of HRQOL with Symptom Patterns in an Online Cohort of Patients with Interstitial Cystitis/Bladder Pain Syndrome.","authors":"Anthony Galvez, Paige Kuhlmann, Margot Barker, Andrew Chen, Victoria Scott, Karyn Eilber, Jennifer Anger","doi":"10.1016/j.urology.2025.06.054","DOIUrl":"https://doi.org/10.1016/j.urology.2025.06.054","url":null,"abstract":"<p><strong>Objectives: </strong>To explore the differences in symptom patterns and management between individuals with IC/BPS who have high vs low self-reported health related quality of life (HRQOL).</p><p><strong>Methods: </strong>An anonymous 40-question online survey assessed IC/BPS patients' symptoms, triggers, management strategies, and comorbidities. Recruitment was through the Interstitial Cystitis Association's Facebook page. HRQOL was rated on a 0-10 Likert scale, grouping respondents into low-impact (0-3), intermediate (4-6), and high-impact (7-10). Univariate analysis included chi-square, Fisher's exact test, and t-tests.</p><p><strong>Results: </strong>Among 451 respondents, 53 (12%) reported low disease impact, while 279 (62%) had high impact. The high-impact group was more frequently triggered by mental health issues (50% vs 32%, p=0.016) and exercise (14% vs 4%, p=0.040), while the low-impact group was more often triggered by allergies (6% vs 1%, p=0.054) and coffee (11% vs 3%, 0.005). High-impact individuals had higher rates of comorbidities including pelvic floor dysfunction (39% vs 19%, 0.005), irritable bowel syndrome (36% vs 21%, p=0.029), overactive bladder (30% vs 17%, p=0.051), and/or vulvodynia (23% vs 9%, p=0.026).</p><p><strong>Conclusions: </strong>IC/BPS encompasses a spectrum of disease manifestations. While demographics remain relatively uniform in this IC/BPS population, symptom patterns, comorbidities, and therapeutic choices are correlated with impact on quality of life.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-09DOI: 10.1016/j.urology.2025.06.068
Javier E Santiago, Min Soo Choo, Richard Mora, Evgeniy Kreydin, David A Ginsberg, Natalia Hernandez, Paola Bustillos, Rose Khavari, Renee M Cole, Stephanie Daignault-Newton, John T Stoffel
{"title":"Outcomes for Stress Incontinence Procedures for Men and Women with Neurogenic Lower Urinary Tract Dysfunction: A Multicenter Neurogenic Bladder Research Group Study.","authors":"Javier E Santiago, Min Soo Choo, Richard Mora, Evgeniy Kreydin, David A Ginsberg, Natalia Hernandez, Paola Bustillos, Rose Khavari, Renee M Cole, Stephanie Daignault-Newton, John T Stoffel","doi":"10.1016/j.urology.2025.06.068","DOIUrl":"https://doi.org/10.1016/j.urology.2025.06.068","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the efficacy and durability of procedures to treat stress urinary incontinence (SUI) in male and female patients with neurogenic lower urinary tract dysfunction (NLUTD).</p><p><strong>Methods: </strong>A retrospective multi-institutional review by the Neurogenic Bladder Research Group of male and female patients with NLUTD who underwent urethral bulking injection (UBI), sling placement, or artificial urinary sphincter (AUS) for SUI between 2012-2020 was performed. The primary outcome was time to procedural failure, defined as return to baseline pre-operative SUI symptoms and/or needing additional procedures for SUI. Men and women were analyzed separately, and univariate and multivariable models were constructed.</p><p><strong>Results: </strong>Forty-five males and thirty-five females were included. The majority had a diagnosis of spina bifida (men - 60%, female - 28%) or spinal cord injury (men - 15%, female -35%). Median age for males was 33 years with median post-operative follow-up of 627 days. Six-month failure rates and median time-to-failure were: UBI - 53% and 5.3 months; sling - 21% and 42 months; AUS - 21%. Median age for females was 44 years with median post-operative follow-up of 363 days. Six-month failure rates and median time-to-failure were: UBI - 68% and 2.6 months; sling - 50% and 7.3 months. Prior bladder reconstruction and spinal cord injury were associated with failure in males; prior urethral surgery was associated with failure in females.</p><p><strong>Conclusions: </strong>SUI surgery outcomes differ between males and females with shorter failure free survival with UBI compared to AUS and sling in males, while UBI and sling placement both demonstrated short failure-free survival in females.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-04DOI: 10.1016/j.urology.2025.07.003
Mehmet Cetin, Cagri Akin Sekerci, Turker Altuntas, Onur Can Ozkan, Yiloren Tanidir, Selcuk Yucel, Tufan Tarcan, Kamil Cam
{"title":"THE EFFECT OF VIDEO USE ON THE ANXIETY LEVELS OF PARENTS OF CHILDREN UNDERGOING ORCHIOPEXY: A PROSPECTIVE RANDOMIZED CONTROLLED STUDY.","authors":"Mehmet Cetin, Cagri Akin Sekerci, Turker Altuntas, Onur Can Ozkan, Yiloren Tanidir, Selcuk Yucel, Tufan Tarcan, Kamil Cam","doi":"10.1016/j.urology.2025.07.003","DOIUrl":"https://doi.org/10.1016/j.urology.2025.07.003","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect that an educational animated video has on the anxiety and depression levels of parents with children undergoing orchiopexy, a commonly performed surgery in pediatric urology, this study builds on previous findings that preoperative multimedia tools can effectively reduce parental anxiety.</p><p><strong>Methods: </strong>Parents of children scheduled for orchiopexy between 15/12/2023 and 15/10/2024 were enrolled. Exclusion criteria included prior urological surgery or additional procedures. Children were randomized into two groups. Group 1 received the standard informed consent form and verbal information three days preoperatively, while group 2 additionally watched a 6-minute educational video. Hospital Anxiety and Depression Scale (HADS), Beck Anxiety Inventory (BAI), and State-Trait Anxiety Inventory (STAI) scores were obtained preoperatively and one week postoperatively.</p><p><strong>Results: </strong>Seventy-four children with a median age of 5.5 (1-13) years were randomized into two groups (37 per group). Mothers were primary caregivers in 74.3% of cases. Anxiety and depression scores significantly decreased postoperatively in both groups, except for STAI-II. Group 2 had significantly lower preoperative HADS-T (11-6), BAI (3-1), and STAI-I (41-35) scores and lower postoperative HADS-D (4.5-2) and STAI-I (36.5-26.5) scores (p=0.029, p=0.008, p=0.007, p=0.041, p=0.043, retrospectively). Bilateral cases had higher anxiety and depression scores (p=0.019). Multimedia use was more effective in parents with higher education (p=0.001).</p><p><strong>Conclusions: </strong>This prospective randomized trial is the first to demonstrate that preoperative multimedia video education significantly reduces anxiety and depression levels in parents of children undergoing orchiopexy.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-04DOI: 10.1016/j.urology.2025.07.002
Megan A Stout, Jessica H Hannick, Lauren E Corona
{"title":"Fertility Preservation in Pediatric Cancer Patients.","authors":"Megan A Stout, Jessica H Hannick, Lauren E Corona","doi":"10.1016/j.urology.2025.07.002","DOIUrl":"https://doi.org/10.1016/j.urology.2025.07.002","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-04DOI: 10.1016/j.urology.2025.07.001
Omri Schwarztuch Gildor, Elad Yosef, Netanel Levin, Anna Itshak, Rony Vainrib, Michael Vainrib
{"title":"Antibiotic prophylaxis before urodynamics: A urine culture-based versus risk-factors-based protocol to minimize usage in the era of antibiotic resistance.","authors":"Omri Schwarztuch Gildor, Elad Yosef, Netanel Levin, Anna Itshak, Rony Vainrib, Michael Vainrib","doi":"10.1016/j.urology.2025.07.001","DOIUrl":"https://doi.org/10.1016/j.urology.2025.07.001","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologyPub Date : 2025-07-01DOI: 10.1016/j.urology.2025.06.069
Trevor C Hunt, Benedikt M Winzer, George K Siodis, Jean-Pierre Trey Kanumuambidi, Scott O Quarrier, Hani H Rashid
{"title":"Applicant Preferences and Perspectives in the New Era of the Urology Residency Match.","authors":"Trevor C Hunt, Benedikt M Winzer, George K Siodis, Jean-Pierre Trey Kanumuambidi, Scott O Quarrier, Hani H Rashid","doi":"10.1016/j.urology.2025.06.069","DOIUrl":"https://doi.org/10.1016/j.urology.2025.06.069","url":null,"abstract":"<p><strong>Objective: </strong>To assess urology residency applicants' preferences and perspectives regarding key issues in a new urology match era that includes both in-person and virtual interviews.</p><p><strong>Methods: </strong>Applicants to our residency program from the 2024-2025 AUA match cycle were surveyed. Issues assessed included interview format preferences, costs, ability to judge \"fit\" with programs, and decisions made throughout the application cycle. When applicable, items were grouped by time point as pre-interview, day of interview, or post-interview.</p><p><strong>Results: </strong>Response rate was 45% (75/166). Applicants attended 13 interviews on average, 7 in person and 6 virtual. Only 10% of invitations included a hybrid option, and just 9% offered any financial aid. Applicants strongly preferred in-person interviews (49.3%) or hybrid formats (40.0%) compared to virtual (10.7%). For judging fit, an even larger majority preferred in-person (76.0%) over virtual (4.0%), especially on the interview day itself. Applicants spent $4,994 total (applications: $1,913, interviews: $3,081), averaging $410 per in-person interview. Nearly all applicants felt the costs and travel time of in-person interviewing were worth it (91% and 95%, respectively). However, 19% of applicants had to decline one or more in-person interviews due to costs.</p><p><strong>Conclusions: </strong>Urology applicants now largely favor in-person interviews over virtual, especially when judging \"fit\", and believe they are worth the increased costs and logistical challenges. However, financial constraints limited the access to interview opportunities for a substantial cohort. Future innovations in the urology match may explore broader implementation of hybrid interview formats as issues of applicant preferences and equity are balanced.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}