The Artificial Urinary Sphincter Improves Emotional Health in Men with Stress Urinary Incontinence: Results from the Prospective, Multi-institutional AUSCO Study.
Andrew C Peterson, Hadley M Wood, Jeremy Myers, Benjamin N Breyer, Bradley A Erickson, Thomas G Smith Iii, Erin L Chaussee, Melissa R Kaufman, Ryan Terlecki, Niels V Johnsen, Alex J Vanni, Daniel Moon, LeRoy Jones, Joshua A Broghammer, Gerard Henry, Arthur L Burnett, Lewis Wen Loong Chan, Brian J Flynn, Rose Khavari, Sean Elliott
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引用次数: 0
Abstract
Objective: To examine the effects on depression, anxiety and overall emotional health in patients undergoing artificial urinary sphincter (AUS) surgery for stress urinary incontinence (SUI). Few reports focus on the impact of AUS implantation on emotional health in men with SUI.
Methods: The Artificial Urinary Sphincter Clinical Outcomes Trial (AUSCO) was a prospective, single-arm, multi-site study designed to evaluate outcomes in men with SUI treated with the AMS 800™ AUS (NCT04088331). A total of 115 subjects were implanted. Follow-up assessments at 3-, 6-, and 12-months post device activation were compared to baseline. These analyses focus on emotional health, measured with the Incontinence QOL (I-QOL), Incontinence Impact Questionnaire (IIQ-7), and EQ-5D-5L.
Results: At 12 months, 100 had completed QOL assessments. Depression rating (Item 5, I-QOL) significantly improved, with 85% (85/100) of patients reporting feeling at least "a little" depressed at baseline decreasing to 39% (39/100) at 12 months (p<0.0001). Emotional health rating (Item 6, IIQ-7) also improved, with 16% (16/100) reporting being "greatly" affected by incontinence at baseline decreasing to 3% (3/100) at 12 months (p<0.0001). The anxiety/depression domain on the EQ-5D-5L (Item 5) was also significantly improved, with 50% (50/100) of patients reporting being at least "slightly" anxious or depressed at baseline decreasing to 30% (30/100) at 12 months (p = <0.0001).
Conclusions: These data demonstrate that treatment of SUI with the AUS improves emotional health in men with SUI.
期刊介绍：
Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology
The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.
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