Urology最新文献

{"title":"Editorial Comment on “Comparative Efficacy of Dorsal-Onlay and Ventral-Inlay Buccal Mucosal Graft Urethroplasty in Female Urethral Stricture: A Randomized Clinical Trial”","authors":"Jovo Bogdanović , Sandra Trivunić-Dajko","doi":"10.1016/j.urology.2025.02.048","DOIUrl":"10.1016/j.urology.2025.02.048","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 59-60"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment on “The Impact of Abortion Laws on the Decision to Undergo Vasectomy”","authors":"Brittany Berk, Raevti Bole","doi":"10.1016/j.urology.2025.03.043","DOIUrl":"10.1016/j.urology.2025.03.043","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 77-78"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urobiome and Inflammation: A Systematic Review on Microbial Imbalances and Diagnostic Tools for Urinary Disorders","authors":"Sara Palumbo ,&nbsp;Giuseppe Lucarelli ,&nbsp;Francesco Lasorsa ,&nbsp;Rocco Damiano ,&nbsp;Riccardo Autorino ,&nbsp;Achille Aveta ,&nbsp;Gianluca Spena ,&nbsp;Sisto Perdonà ,&nbsp;Pierluigi Russo ,&nbsp;Carlo Giulioni ,&nbsp;Angelo Cafarelli ,&nbsp;Marco Finati ,&nbsp;Salvatore Siracusano ,&nbsp;Savio Domenico Pandolfo","doi":"10.1016/j.urology.2025.03.050","DOIUrl":"10.1016/j.urology.2025.03.050","url":null,"abstract":"<div><h3>OBJECTIVE</h3><div>To synthesize current knowledge on urobiome alterations, innovative diagnostic advancements, and emerging therapeutic strategies targeting urobiome dysbiosis in inflammatory urinary tract disorders, including urinary tract infections, nongonococcal urethritis, and interstitial cystitis.</div></div><div><h3>METHODS</h3><div>A systematic review was conducted by screening the most important scientific databases. The search included the keywords: (microbiome) OR (microbial) OR (bacteria) OR (bacterial profile) AND (urine) OR (urinary) AND (first-morning sample) OR (first void). Only original studies in English involving human specimens were considered.</div></div><div><h3>RESULTS</h3><div>Of the 760 articles initially identified, a final sample of 20 original studies met the inclusion criteria. Disruptions in the urobiome composition were associated with increased colonization by pathogens such as <em>Escherichia coli</em> and <em>Mycoplasma genitalium</em>, resulting in inflammation and recurrent urinary conditions. Advanced diagnostic techniques, including metaproteomics, metagenomics, and point-of-care assays such as <em>Neisseria gonorrhoeae</em> lateral flow assay, demonstrated enhanced capabilities for rapid pathogen detection and differentiation of inflammatory conditions. Therapeutic interventions targeting urobiome dysbiosis, particularly probiotics (<em>Lactobacillus rhamnosus</em>, <em>L. reuteri</em>, <em>L. crispatus</em>), showed promising efficacy in reducing recurrence and inflammation in clinical trials.</div></div><div><h3>CONCLUSION</h3><div>Urobiome dysbiosis plays a critical role in inflammatory urinary tract disorders. Innovative diagnostic methods and targeted therapeutic approaches, especially probiotics, offer substantial potential to improve patient outcomes. Further research is warranted to refine these strategies and validate their clinical applicability.</div></div>","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 206-215"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urologist’s Fatigue and Discomfort in Different Body Regions After Performing Flexible Ureteroscopy","authors":"Sarah Razavi ,&nbsp;Emeka Udedibia ,&nbsp;Kristin L. Chrouser ,&nbsp;Hamid Norasi ,&nbsp;M. Susan Hallbeck ,&nbsp;Arun Rai ,&nbsp;Stephanie Izard ,&nbsp;Karen Huang ,&nbsp;David Hoenig ,&nbsp;Zeph Okeke","doi":"10.1016/j.urology.2025.04.004","DOIUrl":"10.1016/j.urology.2025.04.004","url":null,"abstract":"<div><h3>Objective</h3><div>To assess self-reported surgeon fatigue and discomfort in different body regions after performing flexible ureteroscopy.</div></div><div><h3>Methods</h3><div>An anonymous survey was designed and distributed among urologists and trainees in four hospitals. Participants rated their discomfort in different body and hand regions as well as overall fatigue before and immediately after each flexible ureteroscopy procedure they performed.</div></div><div><h3>Results</h3><div>The final working sample size was 45 unique surgeons (26 female and 19 male) completing 58 procedures. Respondents were 38.2 ± 14.7 years of age. Forty-two percent of respondents were male, 75% were right-hand dominant, and 25% reported existing musculoskeletal disorder. Urologists’ overall fatigue score significantly increased after ureteroscopy, but females had a significantly larger increase (female <span><math><mi>β</mi></math></span>: 1.74, <em>P</em> &lt;.001; male <span><math><mi>β</mi></math></span>: 0.78, <em>P</em> = .017). Women experienced higher discomfort in neck, upper back, right shoulder, and right elbow than men. Across different hand regions, increased post-procedural discomfort was reported mostly in the thenar area (41.8%), followed by the hypothenar area (28.5%) and thumb area (27.9%).</div></div><div><h3>Discussion</h3><div>Urologists experience significant increase in overall fatigue and discomfort across most body and hand regions. Women seem to be disproportionally affected. Additional studies are needed to determine the causality of these findings and explore potential interventions aimed at reducing procedure-related discomfort among all urologists, especially women.</div></div>","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 238-244"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory Myofibroblastic Tumor of the Bladder in Childhood: A Three Case Series","authors":"Leah E. Beland ,&nbsp;Jason P. Van Batavia ,&nbsp;Sameer Mittal ,&nbsp;Thomas F. Kolon ,&nbsp;Lea F. Surrey ,&nbsp;Christopher J. Long","doi":"10.1016/j.urology.2025.02.045","DOIUrl":"10.1016/j.urology.2025.02.045","url":null,"abstract":"<div><div>Inflammatory myofibroblastic tumor (IMT) is a rare soft tissue tumor that predominantly affects children and young adults. While it can involve multiple organ systems, IMT of the bladder is remarkably uncommon. We present three pediatric cases of bladder IMT, describing the presentation, evaluation, management, and current follow-up of each. Two patients were successfully managed with targeted therapies, whereas one patient was trialed on non-steroidal anti-inflammatory drugs (NSAIDs) but ultimately required surgical intervention. This series underscores the complexity of managing IMT of the bladder and highlights the importance of individualized treatment strategies that consider tumor biology while striving to reduce treatment-related morbidity.</div></div>","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages e72-e75"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ureteral Tissue Temperature During Ureteroscopy With Ho:YAG Laser Activation in an In Vivo Porcine Model","authors":"Anthony F. Bonzagni ,&nbsp;Timothy L. Hall ,&nbsp;Ron Marom ,&nbsp;Khurshid R. Ghani ,&nbsp;William W. Roberts","doi":"10.1016/j.urology.2025.02.043","DOIUrl":"10.1016/j.urology.2025.02.043","url":null,"abstract":"<div><h3>Objective</h3><div>To measure temperature of the outer ureteral wall and calculate thermal dose with different irrigation and laser power settings during ureteroscopy in a porcine in vivo model.</div></div><div><h3>Methods</h3><div>The ureters of two porcine subjects were exposed through laparotomy incisions. A length of PFA tubing, with equally spaced windows, was inserted into the ureter through a ureterotomy. An array of thermocouples was positioned on the outside of the ureter, colocated with the windows. A LithoVue Elite (Boston Scientific) ureteroscope with a wire thermocouple attached was inserted into the tube adjacent to the ureteral windows. Trials of 60 seconds laser activation were performed at different power and irrigation rates. Thermal dose was calculated at each thermocouple with the threshold of thermal injury considered to be 120 equivalent minutes.</div></div><div><h3>Results</h3><div>All trials conducted with 8 mL/min irrigation: 20 W laser power produced elevated ureteral temperatures. Thermal doses exceeded the thermal injury threshold along a 3 cm length of ureter in some cases. 67% of trials using 15 mL/min irrigation: 30 W laser power also produced suprathreshold thermal doses within ureteral tissue. Employing a 50% operator duty cycle at these same settings decreased thermal dose below threshold. Thermal dose did not reach the threshold of thermal injury in any trials with 40 mL/min irrigation.</div></div><div><h3>Conclusion</h3><div>Ureteroscopy in a porcine model with commonly used irrigation rates and laser settings can elevate ureteral temperatures and produce thermal doses above the threshold of thermal injury.</div></div>","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 11-17"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment on “Simultaneous Bilateral PCNL: Is It Cost-Effective?”","authors":"David T. Tzou","doi":"10.1016/j.urology.2025.03.030","DOIUrl":"10.1016/j.urology.2025.03.030","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Page 51"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Vacuum Erection Device User Feedback: A GPT-4 Thematic Analysis","authors":"Hiren V. Patel ,&nbsp;Behzad Abbasi ,&nbsp;Kevin D. Li ,&nbsp;Marvin Carlisle ,&nbsp;Anna Faris ,&nbsp;William A. Pace ,&nbsp;Benjamin N. Breyer","doi":"10.1016/j.urology.2025.03.027","DOIUrl":"10.1016/j.urology.2025.03.027","url":null,"abstract":"<div><h3>Objective</h3><div>To explore consumer viewpoints regarding vacuum erection device (VED) use.</div></div><div><h3>Methods</h3><div>We conducted a qualitative analysis of 1500 <span><span>Amazon.com</span><svg><path></path></svg></span> reviews for 21 of the most popular VED products. Reviews were analyzed using GPT-4, identifying common themes and subthemes. Electric and manual VEDs were compared, and a multivariable ordinal regression was built to identify factors linked to higher product ratings.</div></div><div><h3>Results</h3><div>The most common themes identified were efficacy (92%) and user experience (78%). Safety and warning mentions appeared in 27% and 6.8% of reviews, respectively. Compared to manual, electric VEDs were more frequently associated with mentions of ease of use (46% vs 34%), design features (17% vs 9.3%), and explicit product warnings (7.7% vs 5.1%). A 5/5 rating was linked to fewer mentions of product deficiency (7.3% vs 86%), malfunction (1.5% vs 45%), product warnings (2.8% vs 24%), and customer service issues (3.9% vs 21%) compared to a 1/5 rating. Among all reviews, 126 (8.4%) reported using the VED for partner intimacy, while 16 (1.1%) noted its use for masturbation. Within this cohort, 65% used devices with included sex toys, and 35% used standard VEDs. Users seeking partner intimacy reported similar effectiveness (93% vs 81%), ease of use (59% vs 54%), satisfaction (91% vs 95%), and likelihood of recommendation (30% vs 29%) between VEDs with and without sex toy features.</div></div><div><h3>Conclusion</h3><div>Amazon reviews indicate a generally positive sentiment toward VEDs, with few mentions of malfunction or safety warnings. However, proper patient education remains essential to ensure safe use and minimize the risk of injury.</div></div>","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 216-222"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Editorial Comment on “Evaluating Noise Emissions of Endourological Lasers: A Comparative Analysis of Ho:YAG, Tm:YAG, and Thulium Fiber Laser Systems”","authors":"Moretto Stefano ,&nbsp;Traxer Olivier ,&nbsp;Quarà Alberto ,&nbsp;Madden Aideen ,&nbsp;Cabrera Johan ,&nbsp;Zorzi Federico ,&nbsp;Bravo-Balado Alejandra ,&nbsp;Corrales Mariela ,&nbsp;Candela Luigi ,&nbsp;Berthe Laurent ,&nbsp;Doizi Steeve ,&nbsp;Panthier Frederic","doi":"10.1016/j.urology.2025.03.021","DOIUrl":"10.1016/j.urology.2025.03.021","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 38-39"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Editorial Comment on “Characterization of Newborn Circumcision Revisions and Complications Among Privately Insured Boys in the United States Between 2010 and 2022”","authors":"David D. Kim ,&nbsp;Max J. Hyman ,&nbsp;Parth K. Modi ,&nbsp;Emilie K. Johnson","doi":"10.1016/j.urology.2025.03.047","DOIUrl":"10.1016/j.urology.2025.03.047","url":null,"abstract":"","PeriodicalId":23415,"journal":{"name":"Urology","volume":"200 ","pages":"Pages 164-165"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}