{"title":"Predictive factors of non-invasive follicular thyroid neoplasm with papillary-like nuclear features: A single-center study.","authors":"Saadia Makni, Yosra Loukil, Rania Kharrat, Meriam Triki, Mouna Zghal, Fatma Kolsi, Naourez Gouiaa, Tahya Sellami Boudawara, Ilhem Charfeddine, Manel Mellouli","doi":"10.47717/turkjsurg.2026.2025-10-18","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-10-18","url":null,"abstract":"<p><strong>Objective: </strong>Distinguishing preoperative criteria and postoperative histological features of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) from those of other thyroid tumors with follicular architecture and papillary nuclear features (non-NIFTP) is crucial to prevent overtreatment. In this study, we aim to identify the predictive factors of NIFTP.</p><p><strong>Material and methods: </strong>We conducted a retrospective study in which we collected cases of thyroid tumors with follicular architecture and papillary nuclear features diagnosed between 2012 and 2022. Clinicopathological characteristics, therapeutic modalities, and follow-up were compared between NIFTP and non-NIFTP tumors.</p><p><strong>Results: </strong>Forty cases of NIFTP and 44 cases of non-NIFTP were identified. NIFTP accounted for 8.83% of all PTCs and 33.6% of all thyroid tumors with follicular architecture and papillary nuclear features. NIFTP was associated with younger age (p=0.005), isoechoic nodules on ultrasound (US) (p=0.004), regular contours (p=0.028), absence of microcalcifications (p=0.005), and predominance in European Thyroid Imaging Reporting and Data System 2 and 3 scores (p<0.001). They predominantly exhibited a nuclear score of 2 (p<0.001), focal nuclear abnormalities (p=0.015), and a thin capsule (p=0.004). No case of NIFTP showed distant or lymph node metastases. Multivariate analysis identified a nuclear score of 2, focal nuclear abnormalities, and a thin tumor capsule as independently associated with NIFTP.</p><p><strong>Conclusion: </strong>Our findings demonstrated the indolent nature of NIFTP and the utility of cervical US in raising preoperative suspicion for this entity. Because findings regarding the Bethesda classification were not available in our study, a prospective multicenter study with a larger sample size and a longer follow-up period is warranted to address this limitation.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lemmel syndrome: A single-center cohort and diagnostic considerations.","authors":"Ender Ergüder, Serkan Demir, Muhammed Salih Süer, Şehnaz Evrimler, Şener Balas","doi":"10.47717/turkjsurg.2026.2025-11-25","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-11-25","url":null,"abstract":"<p><strong>Objective: </strong>Lemmel syndrome is an uncommon cause of obstructive jaundice resulting from extrinsic compression of the common bile duct by a periampullary duodenal diverticulum (PAD) in the absence of choledocholithiasis. Due to its non-specific clinical presentation, diagnosis may be delayed or misinterpreted.</p><p><strong>Material and methods: </strong>A retrospective review was conducted on 12 patients diagnosed with Lemmel syndrome at a single tertiary center between 2022 and 2024. Demographic characteristics, clinical presentation, laboratory findings, imaging modalities [ultrasonography (USG), computed tomography (CT), magnetic resonance cholangiopancreatography (MRCP)], endoscopic interventions, and outcomes were analyzed descriptively.</p><p><strong>Results: </strong>The cohort included 12 patients with a mean age of 70±9 years. All patients presented with clinical or biochemical evidence of obstructive jaundice. USG frequently failed to establish the diagnosis, whereas CT and particularly MRCP demonstrated the anatomical relationship between the PAD and the biliary tree. Endoscopic retrograde cholangiopancreatography served both diagnostic and therapeutic purposes, with biliary stenting performed when indicated. Most patients improved with conservative and/or endoscopic management.</p><p><strong>Conclusion: </strong>Lemmel syndrome should be considered in elderly patients with unexplained obstructive jaundice. Cross-sectional imaging, particularly MRCP, plays a key role in diagnosis, while endoscopic intervention remains central to management.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zaid Safauldeen Ali Alsheikh, Tao Qingsong, Liu Qinjie, Chen Youkun
{"title":"Re-arming checkpoint blockade in MSS colorectal cancer: A precision-microbiome playbook from mechanisms to clinic.","authors":"Zaid Safauldeen Ali Alsheikh, Tao Qingsong, Liu Qinjie, Chen Youkun","doi":"10.47717/turkjsurg.2026.2025-8-3","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-8-3","url":null,"abstract":"<p><p>Immune checkpoint blockade transforms outcomes for the 15% of colorectal cancers (CRCs) with mismatch-repair deficiency; yet most tumours remain refractory. Beneficial gut microbes can change this. <i>Akkermansia muciniphila</i>, <i>Bacteroides fragilis</i>, and short-chain fatty acid producers prime dendritic cells to produce interleukin (IL)-12, polarise Th1 cells, and reinvigorate CD8<sup>+</sup> T-cells. Antibiotics, Western-style diets, and <i>Fusobacterium nucleatum</i> foster myeloid suppression and β-catenin- or IL-17-mediated signalling, which blunt checkpoint activity. Multi-omics analyses link biosynthetic genes for inosine, riboflavin, and folate to durable clinical benefit. Faecal microbiota transplantation from responders has produced objective regressions in otherwise refractory microsatellite-stable disease. This narrative review maps CRC-microbiota-immune crosstalk, evaluates biomarkers and interventions, and proposes a CRC-specific, three-tiered clinical algorithm. We outline standards for trial design and manufacturing processes to facilitate the translation of microbiota-guided therapy into routine practice.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgeons' preferences in the management of recurrence after laparoscopic inguinal hernia repair: A nationwide survey.","authors":"Ömer Çelik, Remzi Can Çakır","doi":"10.47717/turkjsurg.2026.2026-1-1","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2026-1-1","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate contemporary surgical approaches and decision-making patterns of general surgeons in the management of recurrent inguinal hernia following laparoscopic inguinal hernia repair (LIHR), with particular emphasis on recurrence timing, surgeon experience, and annual laparoscopic case volume.</p><p><strong>Material and methods: </strong>The questionnaire consisted of 26 items, including both multiple-choice and short-answer questions, and was designed to assess demographic characteristics, surgical experience, preferred surgical techniques, preoperative evaluation strategies, and management approaches for recurrent inguinal hernia following LIHR. Recurrences were classified as early (≤2 years) or late (>2 years) based on the postoperative time interval.</p><p><strong>Results: </strong>A total of 179 surgeons participated in the survey. Most respondents were male and had ≤10 years of surgical experience. Surgeons with higher annual laparoscopic hernia repair volumes were significantly more likely to prefer re-laparoscopic posterior approaches for both early and late recurrences, whereas surgeons with lower case volumes predominantly favored open anterior repair techniques (p<0.05). Surgical preferences also varied in female patients and according to the initial repair technique (transabdominal preperitoneal or total extraperitoneal). Nearly two-thirds of participants reported insufficient or only partially sufficient training in recurrent hernia repair, while the majority strongly agreed on the need for national or international clinical guidelines.</p><p><strong>Conclusion: </strong>Surgeon experience and annual laparoscopic case volume significantly influence the management of recurrent inguinal hernia following LIHR. As laparoscopic expertise increases, re-laparoscopic approaches are more frequently adopted. These findings highlight the need for standardized training programs and evidence-based guidelines to optimize the management of recurrent inguinal hernia after laparoscopic repair.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Çiğdem Benlice, Nur Ramoğlu, İsmail Ahmet Bilgin, Diğdem Arslan, Arda Ulaş Mutlu, İdris Vural, Sedat Gökay, Makbule Ayşegül Bağda, Bilgi Baca
{"title":"The ergonomic impact of robotic vs. laparoscopic surgery on operating room nurses: A multicenter survey analysis.","authors":"Çiğdem Benlice, Nur Ramoğlu, İsmail Ahmet Bilgin, Diğdem Arslan, Arda Ulaş Mutlu, İdris Vural, Sedat Gökay, Makbule Ayşegül Bağda, Bilgi Baca","doi":"10.47717/turkjsurg.2026.2025-9-23","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-9-23","url":null,"abstract":"<p><strong>Objective: </strong>Robotic surgery is increasingly used across specialties, yet its ergonomic impact on operating room nurses remains underexplored. This multicenter study aimed to evaluate the ergonomic challenges and musculoskeletal discomfort among scrub nurses during robotic surgery and to compare these outcomes with laparoscopic procedures, with additional analysis based on years of robotic surgery experience.</p><p><strong>Material and methods: </strong>This cross-sectional, multicenter, questionnaire-based study was conducted between January and February 2025, among scrub nurses with experience in robotic surgery from multiple centers. Ergonomic perceptions, physical strain, musculoskeletal discomfort, and comparisons between robotic and laparoscopic surgery were assessed. Nurses were stratified into less than and more than 5 years of robotic surgery experience, and comparative statistical analyses were performed.</p><p><strong>Results: </strong>Most nurses rated the robotic operating environment as comfortable (69.6%), and 56.4% reported reduced workload compared with laparoscopy. Physical strain was reported by 30.9%, most commonly during instrument exchange. Musculoskeletal discomfort predominantly affected the neck, back, and shoulders. Shoulder pain was significantly more common among nurses with >5 years of experience (70% vs. 33.3%, p=0.008). Although 71.4% reported ergonomic support from robotic systems, 85.7% had not received ergonomic training.</p><p><strong>Conclusion: </strong>Robotic surgery is perceived by scrub nurses as ergonomically more favorable than laparoscopic surgery; however, substantial musculoskeletal discomfort persists, particularly among more experienced nurses and in the absence of ergonomic training. These findings suggest a potential cumulative ergonomic burden and highlight the need for structured ergonomic education and system-level interventions.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Oruç, Eda Şahingöz, Ece Canpolat, Tezcan Akın, Serdar Gökay Terzioğlu, Erdinç Çetinkaya
{"title":"Pre-procedural predictors of in-hospital mortality in ICU patients undergoing endoscopic PEG placement.","authors":"Mustafa Oruç, Eda Şahingöz, Ece Canpolat, Tezcan Akın, Serdar Gökay Terzioğlu, Erdinç Çetinkaya","doi":"10.47717/turkjsurg.2026.2025-12-39","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-12-39","url":null,"abstract":"<p><strong>Objective: </strong>Percutaneous endoscopic gastrostomy (PEG) is widely used to provide long-term enteral nutrition in patients unable to maintain oral intake. However, PEG placement is already considered a high-risk intervention in the intensive care unit (ICU), where short-term mortality is substantial. This study aimed to identify predictors of in-hospital mortality in ICU patients undergoing PEG.</p><p><strong>Material and methods: </strong>A retrospective cohort study was conducted at a single tertiary center from 2019 to 2024, including all consecutive adult ICU patients who underwent endoscopic PEG. Demographic, clinical, laboratory, and procedural data were analyzed. The primary outcome was in-hospital mortality. Univariate and multivariate logistic regression analyses were used to identify independent predictors.</p><p><strong>Results: </strong>A total of 364 ICU patients underwent PEG, of whom 125 (34.3%) died during the index hospitalization. Among non-survivors, 56 (44.8%) died within the first 14 days after PEG placement. Non-survivors showed lower albumin levels (24.4 vs. 28.2 g/L; p<0.001), higher urea concentrations (57.1 vs. 40.6 mg/dL; p<0.001), higher neutrophil-lymphocyte ratio (6.44 vs. 4.81; p=0.002), and more frequent infection at the time of PEG (88% vs. 58.6%; p<0.001). Prolonged mechanical ventilation (>14 days) was more common among non-survivors (23.2% vs. 11.7%; p=0.005). In the multivariate model, active infection [odds ratio (OR) 3.62; p<0.001], lower albumin (OR 0.90 per g/L; p<0.001), and higher urea (OR 1.02; p=0.05) independently predicted in-hospital mortality, whereas prolonged intubation showed a strong trend but did not reach significance (OR 1.85; p=0.06).</p><p><strong>Conclusion: </strong>ICU patients with active infection, severe hypoalbuminemia, and elevated urea levels have a markedly increased risk of in-hospital mortality after PEG placement. Prolonged mechanical ventilation appears to characterize a clinically more fragile ICU population rather than serving as an independent predictor of mortality. Incorporating these objective markers into pre-procedural assessments may improve patient selection and support decision-making in the ICU.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Gavrilovska-Brzanov, Haris Sulejmani, Sasho Dohcev, Goce Spasovski, Nikola Georgievski, Aleksandar Trifunovski, Dimitar Trajkovski, Marija Jovanovski Srceva, Nikola Brzanov
{"title":"Kidney transplantation in Alport syndrome: A genotype-guided case series and literature review.","authors":"Aleksandra Gavrilovska-Brzanov, Haris Sulejmani, Sasho Dohcev, Goce Spasovski, Nikola Georgievski, Aleksandar Trifunovski, Dimitar Trajkovski, Marija Jovanovski Srceva, Nikola Brzanov","doi":"10.47717/turkjsurg.2026.2025-12-4","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-12-4","url":null,"abstract":"<p><p>Alport syndrome (AS) is a hereditary nephropathy caused by pathogenic variants in COL4A3, COL4A4, or COL4A5, leading to type IV collagen defects and progressive glomerular basement membrane dysfunction. Kidney transplantation provides excellent long-term outcomes; however, donor eligibility, genotype-specific prognosis, and post-transplant complications continue to raise important clinical considerations in the era of precision medicine. We present a comparative case series of three genetically confirmed patients with AS who underwent kidney transplantation: Two with X-linked disease and one with autosomal-dominant inheritance. Genetic, clinical, and immunologic findings were analyzed and contextualized within current literature and recommendations. All patients initially achieved functioning grafts. The autosomal-dominant case demonstrated stable long-term function under cyclosporine-based immunosuppression. Among the X-linked cases, one experienced coronavirus diease-2019-associated arterial thrombosis requiring graft nephrectomy and subsequently underwent successful deceased-donor transplantation one year later; the other developed late antibody-mediated rejection six years post-transplant, with partial recovery following corticosteroid therapy. Kidney transplantation is an effective treatment for AS when guided by molecular confirmation and careful donor evaluation. In this national case series of three patients, outcomes were generally favorable across inheritance types; however, vascular events and late humoral immune complications affected the long-term course of the graft and underscored the need for individualized surveillance.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asmir Jonuzi, Ilhana Tinjak, Benjamin Kulovac, Predrag Ilic, Zlatan Zvizdic
{"title":"Neuroblastoma treatment in children: Single-center case series and review of the literature.","authors":"Asmir Jonuzi, Ilhana Tinjak, Benjamin Kulovac, Predrag Ilic, Zlatan Zvizdic","doi":"10.47717/turkjsurg.2026.2025-9-34","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-9-34","url":null,"abstract":"<p><p>Description of the clinical presentation and tumor behavior, its general and pathological characteristics, diagnostic and therapeutic approaches, as well as treatment outcomes in children with neuroblastoma (NB) at a single-center. Special focus was placed on the duration of the diagnostic process and the correlation between disease stage, presence of metastases, and treatment outcomes. Given the small cohort, this report is presented as a descriptive case series complemented by a focused review of the literature NB. A retrospective study was conducted for the time period from January 1st, 2010, to December 31st, 2024. The study included 13 patients (7 males, 6 females; median age: 44 months; range, 0-114) diagnosed with NB who underwent surgery and were hospitalized at the Department of Pediatric Surgery, Clinical Center of the University of Sarajevo. Demographic, clinical, biochemical, radiological, and treatment data were extracted from medical records. A narrative review of major published NB cohorts was conducted to compare our observations with existing evidence. The median age at diagnosis was 44 months. The largest number of patients were in the age group of 2-4 years, and most presented with stage four disease (according to International Neuroblastoma Staging System classification). The tumor was located in the adrenal gland in 92.3% of cases. The median survival time was 36 months. Patients had elevated serum neuron-specific enolase, urinary vanillylmandelic acid, as well as blood ferritin and lactate dehydrogenase levels. The most common symptoms were loss of appetite, presence of a palpable mass, and abdominal pain. Metastases were present in 76.9% of patients, and stage four was associated with aggressive metastatic dissemination. A multimodal approach was used in treatment. The median time from symptom onset to primary care physician consultation was 12 days, and the median time from physician consultation to diagnosis was 14 days. Relapse occurred in 46.2% of cases, most frequently in patients with stage four disease. A total of 7 patients (46.2%) survived. Advanced-stage disease at diagnosis, metastatic burden, and unfavorable outcomes, are dominating factors in our single-center experience. When compared with larger published cohorts, our findings align with global patterns. Due to inherent sample size limitations, these observations are hypothesis-generating and the need for larger, multicenter studies remains.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burak Karamese, Sukru Toprak Durukan, Engin Bora Sana, Ruwida Sabouni, Ali Berke Uysal, Nadiye Sever, Ibrahim Vedat Bayoglu, Seyhan Hıdıroglu, Gokhan Tazegul
{"title":"Anxiety and screening attitudes in breast cancer patients and their first-degree relatives: A comparative pilot study.","authors":"Burak Karamese, Sukru Toprak Durukan, Engin Bora Sana, Ruwida Sabouni, Ali Berke Uysal, Nadiye Sever, Ibrahim Vedat Bayoglu, Seyhan Hıdıroglu, Gokhan Tazegul","doi":"10.47717/turkjsurg.2026.2025-12-5","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-12-5","url":null,"abstract":"<p><strong>Objective: </strong>Breast cancer is the most common type of cancer in women. Identifying women at risk of breast cancer and ensuring their participation in cancer screening programs have been shown to reduce mortality rates. Therefore, it is important to identify the determinants of attitudes toward breast cancer screening, among which anxiety may play a significant role. This study aimed to explore the screening attitudes and anxiety levels of women with breast cancer and those of their female first-degree relatives within a patient-relative dyadic framework.</p><p><strong>Material and methods: </strong>Breast cancer patients and their female first-degree relatives between the ages of 18-65 were included in this cross-sectional study as a patient-relative dyad. The patients were administered a socio-demographic questionnaire, the breast cancer worry scale, and the attitude towards cancer screening scale.</p><p><strong>Results: </strong>A total of 37 dyads participated in the study. The median age of the entire cohort was 47. Screening participation was reported in 37.1% (13/35) of patients pre-diagnosis and in 29.1% (7/24) of eligible relatives. A negative correlation was found between patients' anxiety and their relatives' screening attitudes (r=-0.395, p=0.016 Spearman's correlation), whereas a positive correlation was found between patients' attitudes and their relatives' attitudes (r=0.501, p=0.002 Spearman's correlation).</p><p><strong>Conclusion: </strong>Higher levels of anxiety in breast cancer patients were associated with less favorable screening attitudes among their relatives, whereas screening attitudes were positively correlated within patient-relative dyads. These findings suggest that anxiety and screening attitudes may cluster within patient-relative dyads. Further research is required to determine the clinical implications.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarkheel Sarshar, Noor-Ul-Huda Bhatti, Momina Amir, Nida Jaffar, Muhammad Hasnain, Syed Ghazi Ali Kirmani, Raza Hussain, Shayan Khalid Ghaloo
{"title":"Role of artificial intelligence in head and neck surgery - A narrative review.","authors":"Sarkheel Sarshar, Noor-Ul-Huda Bhatti, Momina Amir, Nida Jaffar, Muhammad Hasnain, Syed Ghazi Ali Kirmani, Raza Hussain, Shayan Khalid Ghaloo","doi":"10.47717/turkjsurg.2026.2025-3-27","DOIUrl":"https://doi.org/10.47717/turkjsurg.2026.2025-3-27","url":null,"abstract":"<p><p>The advent of artificial intelligence (AI) in the field of head and neck surgery has remarkably impacted in various domains, including investigation, diagnosis, pre-operative decision making, surgical planning, rehabilitation, and so on. Head and neck surgery is a field that is practiced worldwide by otolaryngologists, maxillofacial surgeons, plastic surgeons and general surgeons. It has a number of challenging aspects. This review highlights the current advancements and future prospects in the field and its different applications in cancer detection, peri-operative care, and surgical planning. Deep learning and machine learning (ML) are the pillars of AI, by which huge datasets can be analyzed with precision. This can help to enhance the accuracy and meanwhile minimizing the chances of errors in making clinical decisions. On the other hand, there have been numerous ethical concerns regarding AI. Patient privacy, data security, element of empathy in complex decision making are a few concerns at the top. Like any other advancement, the decision is always taken after weighing risks and benefits. Therefore, instead of abandoning AI as a whole, we must come up with certain regulatory authorities that can keep these issues in check. And this can only happen with worldwide collaborative approach. We conducted this narrative review to summarize recent advancements in head and neck cancer surgery by searching PubMed, Scopus, and Google Scholar from January 2000 to July 2025 using predefined terms related to AI, ML, and head and neck surgery.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}