Turkish Journal of Chemistry最新文献

{"title":"A fast and responsive turn-on fluorescent probe based on a quinone conjugated alkoxy derivative for biothiols and a cellular imaging study.","authors":"Ulviyye Nemetova, Ayşe Nur Önem, Alev Er, Sefa Çelik, Ayşen E Özel, Sevim Akyüz, Mustafa Özyürek, Sibel Şahinler Ayla","doi":"10.55730/1300-0527.3702","DOIUrl":"https://doi.org/10.55730/1300-0527.3702","url":null,"abstract":"<p><p>The detection of intracellular biothiols (cysteine, N-acetyl cysteine, and glutathione) with high selectivity and sensitivity is important to reveal biological functions. In this study, a 2-(2-methoxy-4-methylphenoxy)-3-chloro-5,8-dihydroxynaphthalene-1,4-dione (DDN-O) compound <b>(3)</b> was newly synthesized and used as a fluorogenic probe (detector molecule) in the fluorometric method for the rapid, highly selective, and sensitive determination of biothiols. The intensity values (λ_ex = 260 nm, λ_em = 620 nm) of the product were measured by adding biothiols to the reaction medium at varying concentrations and the glutathione equivalent thiol content values of each biothiol were calculated. Using compound 3, glutathione as the reference biothiol was detected in the linear concentration range of 10-70 μM and the LOD value was found to be 0.11 μM. Biothiol detection with structurally simple compound 3 was performed at the cellular level within 1 min and the probe was also successfully used in bioimaging with low cytotoxicity. It was concluded that this probe can serve as an alternative to existing fluorescence-based biothiol probes with applications in rapid biothiol detection at the cellular level for biological functions. To evaluate the molecular structure of 3, conformational analysis was performed using the PM3 semiempirical method. The most stable obtained molecular geometry was then optimized at the DFT/wb97xd/6-311++G(d,p) level of theory. Frontier molecular orbitals (HOMO and LUMO) and molecular electrostatic potential map analyses were performed for the optimized structure. Molecular docking studies demonstrated the interactions of 3 with HAS (1AO6) and FhGST (2FHE) target proteins.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 6","pages":"830-842"},"PeriodicalIF":1.3,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, characterization, and investigation of photochemical and in vitro properties of novel Zn(II) phthalocyanine.","authors":"Yasemin Bayğu Yildiz, Nilgün Kabay, Burak Yildiz, İpek Ömeroğlu, Mahmut Durmuş, E Rıza Karagür, Hakan Akça, Çağrı Ergin, Yaşar Gök","doi":"10.55730/1300-0527.3699","DOIUrl":"https://doi.org/10.55730/1300-0527.3699","url":null,"abstract":"<p><p>A new nonperipheral zinc(II) phthalocyanine bearing octa carboxylic acid ethyl ester derivative substituted triazole attached propylmercaptothiobenzylmercapto derivative was synthesized via the tetramerization reaction of phthalonitrile. The photochemical in vitro photodynamic activity of zinc(II) phthalocyanine (<b>ZnPc-I</b>), such as human nonsmall cell lung carcinoma cell lines, was investigated in this study. The singlet oxygen generation property of novel zinc(II) phthalocyanine (<b>ZnPc-I</b>) was also examined due to the significantly high singlet oxygen quantum yield of <b>ZnPc-I</b> (F_D = 0.66). The antiproliferative effects of <b>ZnPc-I</b> were also investigated on the A549 and H1299 cell lines, and the results demonstrated that <b>ZnPc-I</b> had a strong antiproliferative effect on both cell lines.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 6","pages":"800-808"},"PeriodicalIF":1.3,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, structure, Hirshfeld surface analysis, and molecular docking studies of the cocrystal between the Cu(II) complex of salicylic acid and uncoordinated piracetam.","authors":"Nazokat N Yuldasheva, Ikram I Abdullaev, Oybek I Khudoyberganov, Lola A Gandjaeva, Pirnazar K Kodamboev, Elyor Sh Samandarov, Adkhamjon S Normamatov, Abror Kh Ruzmetov, Yuldosh Y Yakubov, C Balakrishnan, Bakhtiyar T Ibragimov, Aziz B Ibragimov","doi":"10.55730/1300-0527.3700","DOIUrl":"https://doi.org/10.55730/1300-0527.3700","url":null,"abstract":"<p><p>The cocrystal (or supramolecular complex) between the Cu(II) complex of salicylic acid and uncoordinated piracetam has been synthesized. Its structure is characterized by elemental analysis, FT-IR, UV-Vis spectroscopy, and X-ray crystallography. Spectroscopic methods confirm the formation of the metal complex, while X-ray crystallography establishes the molecular and crystal structure of the obtained compound. The Cu(II) complex of salicylic acid (complex molecule) is a symmetric binuclear compound in the form of a \"Chinese lantern\" and contains 4 salicylic acid and 2 water molecules. It interacts with uncoordinated piracetam through a complicated system of hydrogen bonds. However, according to Hirshfeld surface analysis, the contribution of the O•••H/H•••O contacts is only 24.9%, while H•••H and H•••C/C•••H contacts account for 67.5%, indicating that intermolecular interactions are mainly hydrophobic. In silico (molecular docking) studies of the cocrystal, the complex molecule, and piracetam's antifungal, antibacterial, and antiviral activities confirm that the complex molecule demonstrates enhanced biological activities; practically, the inactive piracetam improved all tested types of bioactivities through cocrystal formation. For example, the binding energy in the case of anti-COVID activity is improved from -10.34 to -11.40 kcal/mol. Thus, cocrystal formation based on metal complexes and inactive organic compounds may be promising in drug design.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 6","pages":"809-820"},"PeriodicalIF":1.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platinum Group Metal (PGM) free multi metallic nanomaterial: a potential electrocatalyst for Ethanol Oxidation.","authors":"Susmita Singh, Prodipta Pal, Soumik Roy, Shalini Basak, Prantica Saha, Anushna Dutta, Sinthia Saha, Mainak Bose","doi":"10.55730/1300-0527.3709","DOIUrl":"10.55730/1300-0527.3709","url":null,"abstract":"<p><p>Comprehensive studies of the ethanol oxidation reaction (EOR) have shown high interest in fuel cell technologies. As anode catalysts, introducing platinum group metal (PGM) free catalyst is promising for higher catalytic activity towards the EOR, as these are cost-effective, pollution-tolerant, and suitable for sustainable energy conversion. In this investigation, multi walled carbon nanotube (MWCNT) supported PGM-free electrocatalysts are synthesized by the impregnation reduction method. The atomic structure, composition, and morphology of nanoalloy catalysts are discovered through X-ray diffraction (XRD), Raman spectroscopy and fourier-transform infrared (FTIR) spectroscopy techniques. Electrochemical behaviours have been analysed by cyclic voltammetry (CV), linear sweep voltammetry (LSV), Chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS), which reveal the oxidation kinetics of ethanol in an alkaline medium on the surface of the catalyst. The structure-activity relationship is a portrait of all the physical and electrochemical analyses that assists in exploring the active site of the surface, which facilitates electrooxidation activity. The C/Fe₅₀Co₅₀ catalyst exhibits higher catalytic efficiency and promotes CO removal through a bifunctional mechanism and electronic effect.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"49 1","pages":"45-53"},"PeriodicalIF":1.3,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of isocyanate containing cryogels for fast (bio)molecular immobilization.","authors":"Merve Bat Özmatara, Tuğçe Nihal Gevrek","doi":"10.55730/1300-0527.3696","DOIUrl":"https://doi.org/10.55730/1300-0527.3696","url":null,"abstract":"<p><p>Cryogels containing isocyanate reactive groups were synthesized via photopolymerization of 2-isocyanoethyl methacrylate (ICEMA) and poly(ethylene glycol) methyl ether methacrylate (PEGMEMA). By changing the PEGMEMA and ICEMA ratios, cryogel series with varying ratios of reactive isocyanate groups were successfully prepared. The cryogels were characterized using Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis, scanning electron microscope, and rheometry. To demonstrate that molecules containing amine groups can be immobilized onto synthesized cryogels through isocyanate-amine reactions, the cryogels were conjugated with 4-(trifluoromethyl)benzylamine (TFBA) and fluorescein amine (FLA) molecules, and the conjugations were confirmed through FTIR and fluorescence microscopy, respectively, for TFBA and FLA. Additionally, immobilization of fluorescein isothiocyanate conjugated albumin from bovine serum (FITC-BSA) as fluorescein-labeled model proteins was studied to illustrate that biomolecules can also be bound to the cryogels without any linker. It was shown that the amount of immobilized FITC-labeled model proteins can be controlled by adjusting the concentration of isocyanate reactive groups within the cryogel matrix, and this functionalization was confirmed by fluorescence microscope.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 5","pages":"770-779"},"PeriodicalIF":1.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, characterization, and Hirshfeld surface analysis of coordination compounds composed of two different aminopyridines, isothiocyanate ligand molecules, and two different transition metal atoms.","authors":"Zarife Sibel Şahin, Zeki Kartal","doi":"10.55730/1300-0527.3697","DOIUrl":"https://doi.org/10.55730/1300-0527.3697","url":null,"abstract":"<p><p>In this article, we describe the successful synthesis of three coordination compounds formed by the ligands 3-aminopyridine, 4-aminopyridine, and isothiocyanate ion with copper atoms and 4-aminopyridine and isothiocyanate ion with cadmium atoms, and their structural characterizations. The crystal structures of the compounds were determined by single crystal X-ray diffraction. According to that technique, the open formulae of these compounds are [Cu(3-aminopyridine)₂(NCS)₂] (<b>1</b>), [Cu(4-aminopyridine)₃(NCS)₂] (<b>2</b>), and [Cd(4-aminopyridine)₂(NCS)Cl] (<b>3</b>). In addition, the suitability of the structures of the compounds was characterized by elemental analysis, thermal analysis, and Fourier transform infrared spectroscopy. The single crystal X-ray diffraction analyses of these coordination compounds showed that the first of these coordination compounds had a 1D crystal structure and the other two had a 3D crystal structure. N-H⋯S, N-H⋯N, N-H⋯Cl, N-H⋯π, and C-H⋯π bonds and their combinations were effective in the formation of the crystal structures of the said coordination compounds. The metal atoms [Cu(II), Cu(II), and Cd(II)] in these coordination compounds were surrounded by various ligand molecules in a square planar, square pyramidal, and octahedral arrangement, respectively. In order to investigate some chemical and structural properties of these coordination compounds, theoretical calculations were performed with the software package Gaussian 03. The highest occupied molecular orbital (HOMO), lowest occupied molecular orbital (LUMO), and natural bond orbital (NBO) values of the coordination compounds were used in these calculations. When the energy gap value between the HOMO and LUMO states of the compounds was examined, it was predicted that compound <b>3</b> may have lower kinetic stability, higher chemical activity, and lower semiconductor properties than all the other compounds. According to the Hirshfeld surface analysis of the compounds, C⋯H, S⋯H, H⋯H, and N⋯H interactions are generally seen in the crystal structures of all compounds. In addition, Cd⋯Cl, Cd⋯S, H⋯Cl, and Cl⋯Cl interactions also occur in compound <b>3</b>.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 5","pages":"780-799"},"PeriodicalIF":1.3,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An overview of sodium-ion batteries as next-generation sustainable electrochemical devices beyond the traditional lithium-ion framework.","authors":"Gamzenur Özsin","doi":"10.55730/1300-0527.3707","DOIUrl":"10.55730/1300-0527.3707","url":null,"abstract":"<p><p>The rise in the popularity of electric vehicles and portable devices has boosted the demand for rechargeable batteries, with lithium-ion (Li-ion) batteries favored for their superior energy and power density. However, supply strains and sustainability issues are driving the search for alternatives. Postlithium technologies, particularly sodium-ion (Na-ion) batteries, are gaining attention for their promising potential and similarity to Li-ion technology. While efforts are still needed to enhance the energy and power density as well as the cycle life of Na-ion batteries to replace Li-ion batteries, these energy storage devices present significant advantages in terms of sustainability, theoretical capacity, and intrinsic safety features. Through this paper, the current state of Na-ion batteries, focusing on key components such as anodes, electrolytes, cathodes, binders, separators, and current collectors, has been critically assessed. Recent advancements, challenges, future directions, and new materials engineering strategies for improving electrochemical performance are also discussed. Overall, this review offers a comprehensive analysis of the development of high-performance, cost-effective, and sustainable energy storage systems.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"49 1","pages":"1-28"},"PeriodicalIF":1.3,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masking of iron and other interferences during the spectrophotometric analysis of aluminum from soil samples using Alizarin Red S.","authors":"Hafiz Zain Ul Aabidin, Muhammad Inam Ul Hassan, Tariq Yasin, Muhammad Zubair Rahim, Ahsan Amin Bhatti, Hamayun Imtiaz, Asif Raza","doi":"10.55730/1300-0527.3713","DOIUrl":"10.55730/1300-0527.3713","url":null,"abstract":"<p><p>In whole-rock geochemical analysis, the quantification of aluminum in geological samples is performed using different analytical techniques including UV-Vis spectrophotometry. During the spectrophotometric analysis of aluminum utilizing Alizarin Red S, iron causes significant interference, leading to inaccurate measurements of the amount of aluminum in the sample. In cases where leached or processed samples contain titanium, interference is also observed. However, appropriate masking agents can remove these interferences. In this study, various masking agents including Tiron, oxalic acid, ascorbic acid, and thioglycolic acid were utilized for the masking of iron. Among these masking agents, ascorbic acid proved to be the best candidate for masking iron. A simple and efficient method was then developed for the masking of iron with the optimization of parameters including concentration of ascorbic acid and reaction time. With this technique, 2 mL of ascorbic acid (10%) can mask iron at up to 3000 ppm in aliquots. Moreover, titanium interference is not observed with this method when the titanium concentration in the aliquot is below 100 ppm. This method was subsequently applied to geological samples and the results were compared to those of atomic absorption spectroscopy. Most samples can easily be analyzed for aluminum by utilizing this masking technique and circumventing interference problems.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"49 1","pages":"89-102"},"PeriodicalIF":1.3,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Polybrominated methoxy- and hydroxynaphthalenes\" [Turkish Journal of Chemistry 40 (2) 2016 332-346 ].","authors":"Kıymet Berkil Akar, Osman Çakmak, Tuncay Tunç","doi":"10.55730/1300-0527.3689","DOIUrl":"https://doi.org/10.55730/1300-0527.3689","url":null,"abstract":"<p><p>[This corrects the article on p. 332 in vol. 40.].</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 4","pages":"701-702"},"PeriodicalIF":1.3,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytotoxicity of norstictic acid derivatives, a depsidone from <i>Ramalina anceps</i> Nyl.","authors":"Danielle Bogo, Isabel Máximo C Alcântara, Glaucia B Alcantara, Ana Camila Micheletti, Neli K Honda, Maria de Fátima C Matos","doi":"10.55730/1300-0527.3694","DOIUrl":"https://doi.org/10.55730/1300-0527.3694","url":null,"abstract":"<p><p>Structural modifications in lichen phenolic compounds have been one of the tools to potentiate their biological activity. In the present work, seven alkyl derivatives of norstictic acid were prepared and evaluated against eight cell lines. Norstictic acid was isolated from the lichen <i>Ramalina anceps</i> and the alkyl derivatives were obtained through reactions with alcohols. Cytotoxicity was evaluated against the 786-0 (kidney carcinoma), MCF7 (breast carcinoma), HT-29 (colon carcinoma), PC-03 (prostate carcinoma), HEP2 (laryngeal carcinoma), B16-F10 (murine melanoma), UACC-62 (human melanoma), and NIH/3T3 (mouse embryonic fibroblast) cell lines using the sulforhodamine B assay. Norstictic acid exhibited poor activity, while the 8'-<i>O</i>-<i>n</i>-butyl-norstictic acid and 8'-<i>O</i>-<i>sec</i>-butyl-norstictic acid derivatives showed potential activity (GI₅₀ values of 6.37-45.0 μM and 6.8-52.40 μM, respectively) and high selectivity (selectivity index (SI) values of 13.88-98.11 and SI 11.30-87.40, respectively) against all tumor cells. The 8'-<i>O</i>-<i>n</i>-hexyl-norstictic acid showed good activity (5.96-9.53 μM) and moderate selectivity (SI 9.2-5.76) against MCF7, HT-29, PC-03, and HEP2 cells, while 8'-<i>O</i>-isopropyl-norstictic acid demonstrated high activity and selectivity against PC-03 cells (GI₅₀ 1.28 μM and SI 33.8), and was highly active but moderately selective against UACC, HEP2, and B16-F10 cells (GI₅₀ 6.2, 7.78, and 9.65 μM; SI 7.0, 5.5, and 4.5, respectively). Additionally, 8'-<i>O</i>-<i>n</i>-pentyl- and 8'-O-<i>tert</i>-butyl-norstictic acids were active and selective against PC-03 cells (GI₅₀ 8.77 and 7.60 μM; SI 6.53 and 5.0, respectively). Chemometric analysis revealed a clear relationship between all compounds and their biological activities. The insertion of a four-carbon alkyl chain (<i>n</i>-butyl and <i>sec</i>-butyl) produced potentially active compounds on all tested tumor cells.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"48 5","pages":"748-755"},"PeriodicalIF":1.3,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}