Trends in Medicine最新文献

{"title":"Haematological abnormalities in patients with severe community acquired pneumonia who did not require mechanical ventilation and in patients with severe pulmonary tuberculosis","authors":"G. Bozóky, É. Ruby","doi":"10.15761/tim.1000207","DOIUrl":"https://doi.org/10.15761/tim.1000207","url":null,"abstract":"During the 10-year follow-up period (2008-2019) authors analyzed the different hematological changes in 1280 hospitalized patients with sever community acquired pneumonia (CAP) who did not require mechanical ventilation. The severity of illness was identified by the „pneumonia serverity index” and by the „CURB” (confusion, urea nitrogen, respiratory rate, blood pressure) severity scores. Normochromic-normocytic type of aneamia was diagnosed in 12% of patients: hypocromic microcytic type of anemia was observed on 8% of patients: immune-mediated-hemolytic anemia occurred in 6 patients. Usual degree of leucocytosis with left shifted periferial blood smear was detected in 32% of patients: extreme degree of leucocytosis was observed in 20%, leucopenia (granulocytopaenia) occured in 16% of patients. Elevated plateled count was defined in 18% while thrombocytopaenia was found in 6% of patients. Authors prospectively followed 380 patients with pulmnary tuberculosis according to the characteristics of chest radiograph and sputum Ziehl-Neelsen’s stain positivity, and a result of quantiferon test. In 380 patients with severe pulmonary tuberculosis anemia was present in 52% of patients: leukocytosis occured in 20% leucopenia, granulocytopedia and lymphopenia was observed in 16% of patients. Elevated platelet count occured in 26% which was compicated with deep vein leg thrombosis in 18 patients. Dysmyelopoietic bone marrow alteration with peripheal pancytopenia was diagnosed in one case as the result of mycobacterial sespsis. This survey has revealed that the various haematological abnormalities are common in cases of community acquired pneumonia, and in patients with severe pulmonary tuberculosis. The other clinical consequence is that the special haematological alterations, such as extreme leucocytosis, leucopenia, granulocytopenia and severe degree of anemia are useful indicators of the severity of lower respiratory tract infection. *Correspondence to: Géza Bozóky, Department of Pulmology and Internal Medicine, Hospital of Bács-Kiskun County Municipality, Bács-Kiskun County, E-mail: bozokyg@freemail.hu Received: September 03, 2019; Accepted: September 20, 2019; Published: September 24, 2019 Introduction Community acquired pneumonia (CAP) is an important healthcare concern, and is the most common cause of death associated with infectious disease and the sixth most comon cause of death [1-3]. The annual incidence rate in the USA 6/1000 in the 18-39 age group, and 34/1000 in people aged 75 [3]. Admission to the hospital in patients with CAP is needed in 20-40% and about 5-10% of these patients are admitted to intnsive care unit (ICU) [3,4]. The mortality rate of CAP in outpatients setting is in the range of <1-5%, but among patients who require hospitalization, the rate averages 12% [1,3]. Severe CAP (sepsis syndrome and septic shock syndrome) has been separeted from cases of less severe pneumonia requiring hopsitalization, because of the high mortality rate ","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78323942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo tumor cerebri caused by Brucellosis: Case report","authors":"M. Ranjbar, Sohrab Aghabeigi, Fatemeh Tahanian, Ahmad Hezarjaribi, S. Nemati","doi":"10.15761/tim.1000215","DOIUrl":"https://doi.org/10.15761/tim.1000215","url":null,"abstract":"Brucellosis is a bacterial zoonotic infection. In endemic areas, brucellosis can manifest with various types of neurological symptoms. Among them, meningitis is the most frequent presentation. Pseudotumor like presentation is also rarely reported. In this report, the patient is a 47-year-old female presenting with pseudotumor cerebri and normal cerebrospinal fluid analysis who finally diagnosed with brucellosis. This case report suggests that neurobrucellosis as a differential diagnosis of psudotumor cerebri especially in endemic areas.","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78365186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of antifungal paper from Trametes versicolor containing orange oil against fungal skin infections: A model based on in vitro studies","authors":"Sirimas Sukmas, T. Aewsiri, N. Matan","doi":"10.15761/TIM.1000186","DOIUrl":"https://doi.org/10.15761/TIM.1000186","url":null,"abstract":"Introduction: Mould infection on the human skin is one of important effects of mould on human health. Skin mould infection is normally caused by Aspegillus, Penicillium and Rhizopus. To date, orange oil has been applied in the present study to inhibit mould infection by adding it into fungal paper. Fungal paper made from Trametes versicolor was used to absorb and slow down the release of orange oil vapour. Therefore, the objective of this work was to investigate the effect of orange oil in fungal paper on growth of infected skin mould as a model in vitro test. Methods: Orange oil and the main component (limonene) was prepared in the Malt Extract Agar (MEA) and added into fungal paper made from T. versicolor at concentrations of 0 (control), 20, 40, 60, 80 and 100 μg g−1. Each of mycelium and spores of Aspergillus niger, Aspergillus flavus, Penicillium chrysogenum and Rhizopus spp were placed on the MEA. A spore of mould was sprayed on the fungal paper. Results: Using 60 μg g−1 of orange oil in MEA and 80 μg g−1 of orange oil in the fungal paper exhibited complete inhibition of growth of all moulds in this test. Limonene alone could not inhibit all moulds in this test; therefore, some minor components of orange can play a significant role in mould growth inhibition. Moreover, fungal paper made from T. versicolor exhibited slow release of orange oil components with active to inhibit mould at least 30 days. Conclusions: Thus, this research demonstrated the potential of fungal paper containing orange oil to control the growth of infected moulds and that this combination could be applied in medicine to control infection of skin in the future. *Correspondence to: Narumol Matan, Food Science and Technology, School of Agricultural Technology, Walailak University, Nakhon Si Thammarat 80160, Thailand and Research Center of Excellence in Innovation of Essential oil, Walailak University, Nakhon Si Thammarat 80160, Thailand, Tel: 6675672359; Fax: 6675672971; E-mail: nnarumol@wu.ac.th; nnarumol@yahoo.com","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76816704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum potassium levels in Thai patients with T2DM and eGFR greater than or equal to 90 ml/min/1.73 m2","authors":"J. Janma, S. Changsirikulchai, P. Sangthawan, N. S. Thokanit, S. Rattanamongkolgul, B. Thinkhamrop","doi":"10.15761/TIM.1000178","DOIUrl":"https://doi.org/10.15761/TIM.1000178","url":null,"abstract":"Background: Disturbances in potassium levels can occur in patients with renal dysfunction. This study’s aim is to describe the serum potassium (sK) levels in Thai patients with type 2 Diabetes (T2DM) with or without hypertension (HT) and with estimated glomerular filtration rates (eGFR) greater than or equal to 90 ml/ minute/1.73 m 2 . Methods : There was a cross sectional study performed throughout Thailand in 2016 for assessment on the quality of care among patients diagnosed with T2DM and HT. We selected a subgroup of patients who had data of sK levels and eGFR value greater than or equal to 90 ml/minute/1.73 m 2 for analyses. Results: There were 3,719 subjects who met the inclusion criteria. The mean (SD) eGFR was 102.59 (9.12) ml/minute/1.73m 2 . The mean (SD)sK level was 4.11 (0.52) mEq/L. The mean (SD) SBP and DBP were 130.86 (15.47) and 76.15 (10.14) mmHg, respectively. The sK levels were categorized into 3 groups: low, normal and high at <3.5, 3.5-5.0 and >5 mEq/L, respectively. The prevalence of hypokalemia was 6.7 % and level less than 3 mEq/L was found in 55.6% of the hypokalemic population. The percentage of hypokalemia was found to be high in the group with diuretic usage. The prevalence of hyperkalemia was 2.9% and levels more than 5.5 mEq/L was found in 21.7% of the hyperkalemic group. Conclusions : The hypokalemia and hyperkalemia in T2DM with or without hypertension and eGFR≥90 ml/minute/1.73 m 2 can be found. The sK levels less than 3 mEq/L could be related to diuretic usage. Therefore, patients who are prescribed diuretics or renin angiotensin aldosterone blockades should have sK levels regularly monitored.","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86389876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between noise annoyance and hearing loss caused by chronic exposure to noise among the workers of an automotive industry","authors":"I. Alimohammadi, Fakhradin Ahmadi Kanrash, J. Abolghasemi, S. Vosoughi, Kazem Rahmani, M. Chalak, M. Anbari","doi":"10.15761/tim.1000203","DOIUrl":"https://doi.org/10.15761/tim.1000203","url":null,"abstract":"Background: As a physical pollutant in the workplace, noise has physiological and psychological consequences for people. Objective: The aim of this study was to investigate the relationship between annoyance and hearing loss in the people exposed to chronic noise in the automotive industry. Methods: 250 workers exposed to sound pressure in the work environment were randomly selected. The DANPLEX-AS54 audiometry device was also used to measure the workers’ hearing levels. Furthermore, an annoyance inventory containing questions numbered 1 to 11 to indicate the level of annoyance was used as well. Results: using Pearson correlation coefficient to evaluate hearing levels and annoyance, we found out a significant positive relationship between annoyance and hearing level at frequencies of 2000, 4000 and 8000 in the left ear, and frequency of 6000 in the right ear (P <0.001). Also, there was a significant relationship between annoyance and NIHL (noise-induced hearing loss) in the left ear, and general conditions (both ears) (P <0.001). Conclusion: The results of this study, showed that there was a significant positive relationship between noise annoyance and hearing loss among the workers, and the likelihood of noise annoyance increased with the incidence of hearing loss. *Correspondence to: Fakhradin Ahmadi kanrash, MSc Student, Department of Occupational Health Engineering, Student Research Committee, School of Public Health, Iran University of Medical Sciences, Tehran, Iran, E-mail: F_ahmadi1367@yahoo.com","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83291651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of positive thinking training on self-efficacy and emotion regulation in men with hemophilia","authors":"M. Beiranvand, Majid Keramati Moghadam, R. Sabounchi, Mahmoud Delphan, Azam Ghafuori, Roghayeh Keramati Moghadam","doi":"10.15761/TIM.1000200","DOIUrl":"https://doi.org/10.15761/TIM.1000200","url":null,"abstract":"Study design: A semi-experimental study (pre-test, post-test, and follow-up with the control group). Summary and background data: Hemophilia as an inherited bleeding creates fundamental changes in the quality of life of hemophiliac population. Patients with hemophilia need to improve the positive relationship with themselves and others by a positive thinking training and the avoidance of negative thoughts as a coping strategy against the problems of their life. Objectives of the study: The purpose of this study was to examine the effectiveness of positive thinking training on self-efficacy and emotion regulation in men with hemophilia. Method: In the present study, 30 patients with hemophilia were selected among all patients with hemophilia (N=129) of Lorestan province. They were randomly assigned to the experimental group (N=15) and control group (N=15). The subjects completed self-efficacy and emotion regulation questionnaires. Seligman’s positive thinking training program was administered to the experiment group in eight 120-minute sessions and the control group received no training. The collected data were analyzed using Covariance statistics method and SPPS software (version 21). Results: The results of this study showed that the self-efficacy and emotion regulation increased significantly in the experimental group when compared to control group. Conclusion: The positive thinking training helps patients with hemophilia to avoid negative thoughts and apply better strategies to cope effectively with problems. Patients’ information processing works more efficiently by positive thinking and it increases self-efficacy and emotion regulation. *Correspondence to: Majid Keramati Moghadam, Department of Sport Management, Faculty of Physical Education and Sport Sciences, Islamic Azad University Borujerd Branch, Borujerd, Iran, Tel: +99166638717; E-mail: majid.keramatimoghadam@gmail.com","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88324882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of five viral nucleic acid extraction kits for the efficient extraction of viral DNA and RNA from cell-free samples","authors":"Bandar Ali Suliman","doi":"10.15761/tim.1000202","DOIUrl":"https://doi.org/10.15761/tim.1000202","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82317105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflections of health leaders’ experiences related dengue solutions from transmitting a technology of larval indices surveillance system in southern Thailand","authors":"Charuai Suwanbamrung","doi":"10.15761/TIM.1000179","DOIUrl":"https://doi.org/10.15761/TIM.1000179","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76579043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Key feature, clinical reasoning problem. Puzzle and scenario writing: Are there any differences between them in evaluating clinical reasoning?","authors":"E. Boushehri, A. Monajemi, Kamran, S. Arabshahi","doi":"10.15761/TIM.1000188","DOIUrl":"https://doi.org/10.15761/TIM.1000188","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74462663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crossing age boundaries; Falls clinic serves as frailty clinic beyond age category","authors":"Kawa Amin","doi":"10.15761/TIM.1000184","DOIUrl":"https://doi.org/10.15761/TIM.1000184","url":null,"abstract":"As a person ages, they are subject to an increased risk of longterm medical conditions, falls, frailty, dementia, dependence and comorbidities [1]. Frailty itself is regarded as a chronic medical condition with potential progression [2]. Older adults with frailty conditions are more likely to be admitted to the Emergency Department [3,4]. One of the most common admission causes, especially in secondary care, is falls [5,6]. Falls are regarded as one of the earliest signs of frailty [7] and are one of the highest complications resulting in hospital admission [5,8].","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74008919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}