泰国T2DM和eGFR患者血清钾水平大于或等于90ml /min/1.73 m2

J. Janma, S. Changsirikulchai, P. Sangthawan, N. S. Thokanit, S. Rattanamongkolgul, B. Thinkhamrop
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引用次数: 1

摘要

背景:肾功能不全患者可出现钾水平紊乱。本研究的目的是描述伴有或不伴有高血压(HT)且肾小球滤过率(eGFR)大于或等于90 ml/ min /1.73 m2的泰国2型糖尿病(T2DM)患者的血清钾(sK)水平。方法:2016年在泰国进行了一项横断面研究,评估诊断为T2DM和HT的患者的护理质量。我们选择了一组sK水平和eGFR值大于或等于90 ml/min /1.73 m2的患者进行分析。结果:3719名受试者符合纳入标准。平均(SD) eGFR为102.59 (9.12)ml/min /1.73 m3 / 2。sK均值(SD)为4.11 (0.52)mEq/L。收缩压和舒张压的平均(SD)分别为130.86(15.47)和76.15 (10.14)mmHg。sK水平分为低、正常和高3组,分别为5 mEq/L。低血钾患病率为6.7%,低血钾人群中低于3 mEq/L的比例为55.6%。在使用利尿剂的组中发现低钾血症的百分比较高。高钾血症的患病率为2.9%,21.7%的高钾血症组高于5.5 mEq/L。结论:伴有或不伴有高血压且eGFR≥90ml /min /1.73 m2的T2DM患者均存在低钾血症和高钾血症。sK水平低于3 mEq/L可能与利尿剂的使用有关。因此,服用利尿剂或肾素血管紧张素醛固酮阻滞剂的患者应定期监测sK水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Serum potassium levels in Thai patients with T2DM and eGFR greater than or equal to 90 ml/min/1.73 m2
Background: Disturbances in potassium levels can occur in patients with renal dysfunction. This study’s aim is to describe the serum potassium (sK) levels in Thai patients with type 2 Diabetes (T2DM) with or without hypertension (HT) and with estimated glomerular filtration rates (eGFR) greater than or equal to 90 ml/ minute/1.73 m 2 . Methods : There was a cross sectional study performed throughout Thailand in 2016 for assessment on the quality of care among patients diagnosed with T2DM and HT. We selected a subgroup of patients who had data of sK levels and eGFR value greater than or equal to 90 ml/minute/1.73 m 2 for analyses. Results: There were 3,719 subjects who met the inclusion criteria. The mean (SD) eGFR was 102.59 (9.12) ml/minute/1.73m 2 . The mean (SD)sK level was 4.11 (0.52) mEq/L. The mean (SD) SBP and DBP were 130.86 (15.47) and 76.15 (10.14) mmHg, respectively. The sK levels were categorized into 3 groups: low, normal and high at <3.5, 3.5-5.0 and >5 mEq/L, respectively. The prevalence of hypokalemia was 6.7 % and level less than 3 mEq/L was found in 55.6% of the hypokalemic population. The percentage of hypokalemia was found to be high in the group with diuretic usage. The prevalence of hyperkalemia was 2.9% and levels more than 5.5 mEq/L was found in 21.7% of the hyperkalemic group. Conclusions : The hypokalemia and hyperkalemia in T2DM with or without hypertension and eGFR≥90 ml/minute/1.73 m 2 can be found. The sK levels less than 3 mEq/L could be related to diuretic usage. Therefore, patients who are prescribed diuretics or renin angiotensin aldosterone blockades should have sK levels regularly monitored.
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