Tropical Medicine and Infectious Disease最新文献_第2页

Micronutrient Biomarkers and Their Association with Malaria Infection in Children in Buea Health District, Cameroon.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-10 DOI: 10.3390/tropicalmed9120303

Jerome Nyhalah Dinga, Emmanuel Fondungallah Anu, Romelle Dibanda Feumba, Haowen Qin, Flora Ayah, Rene Bilingwe Ayiseh, Robert Adamu Shey, Stanley Dobgima Gamua, Anthony Kukwah Tufon, Rameshbabu Manyam, Vincent P K Titanji

{"title":"Micronutrient Biomarkers and Their Association with Malaria Infection in Children in Buea Health District, Cameroon.","authors":"Jerome Nyhalah Dinga, Emmanuel Fondungallah Anu, Romelle Dibanda Feumba, Haowen Qin, Flora Ayah, Rene Bilingwe Ayiseh, Robert Adamu Shey, Stanley Dobgima Gamua, Anthony Kukwah Tufon, Rameshbabu Manyam, Vincent P K Titanji","doi":"10.3390/tropicalmed9120303","DOIUrl":"10.3390/tropicalmed9120303","url":null,"abstract":"Recently malaria and micronutrient deficiencies have become a major worldwide public health problem, particularly in Africa and other endemic countries with children under 5 years old being the most vulnerable. Apart from nutritional problems that cause micronutrient deficiencies, studies have also reported that parasitic infections like malaria can affect the levels of micronutrients. Thus, this research was aimed at assessing the serum levels of micronutrient biomarkers and their association with malaria infection in children under 5 years old in the Buea Health District. Method: This cross-sectional study recruited 80 participants from February to April 2024. The micronutrient biomarkers levels were measured using a Q-7plex Human Micronutrient Measurement Kit. Results: There were changes in serum micronutrient biomarkers levels between malaria infected and healthy children. Ferritin was higher in sick children (23.53 μg/L ± 7.75) than in healthy children (19.07 μg/L ± 3.87), significantly (p < 0.002). The same trend was observed with the soluble transferrin receptor being higher (p < 0.049) in sick children (3.74 mg/L ± 1.92) compared to healthy ones (3.08 mg/L ± 0.64). In addition, the levels of retinol-binding protein 4 and thyroglobulin levels were not significantly different between the sick and healthy children. Therefore, this study revealed that malaria causes alterations in the serum levels of micronutrient biomarkers and consequently affects micronutrient levels in children below the age of 5 in the Buea Health District.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acceptance and Completion Rates of 3-Month Isoniazid-Rifampicin (3HR) Tuberculosis Preventive Treatment (TPT) Among Contacts of Bacteriologically Confirmed TB Patients-Patients' and Healthcare Workers' Perspectives.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-07 DOI: 10.3390/tropicalmed9120301

Austin Ihesie, Ogoamaka Chukwuogo, Rupert Eneogu, Olugbenga Kayode Daniel, Aderonke Agbaje, Bethrand Odume, Debby Nongo, Charles Ohikhuai, Nera Kadiri-Eneh, Omosalewa Oyelaran, Victor Obianeri, Wayne Van Gemert, Enos Okumu Masini, Cleophas D'auvergne, Urhioke Ochuko, Chukwuma Anyaike, Sunday Olakunle Olarewaju

{"title":"Acceptance and Completion Rates of 3-Month Isoniazid-Rifampicin (3HR) Tuberculosis Preventive Treatment (TPT) Among Contacts of Bacteriologically Confirmed TB Patients-Patients' and Healthcare Workers' Perspectives.","authors":"Austin Ihesie, Ogoamaka Chukwuogo, Rupert Eneogu, Olugbenga Kayode Daniel, Aderonke Agbaje, Bethrand Odume, Debby Nongo, Charles Ohikhuai, Nera Kadiri-Eneh, Omosalewa Oyelaran, Victor Obianeri, Wayne Van Gemert, Enos Okumu Masini, Cleophas D'auvergne, Urhioke Ochuko, Chukwuma Anyaike, Sunday Olakunle Olarewaju","doi":"10.3390/tropicalmed9120301","DOIUrl":"10.3390/tropicalmed9120301","url":null,"abstract":"Providing tuberculosis preventive treatment (TPT) to close contacts of persons with TB is a core strategy recommended by WHO for the prevention and control of TB. Nigeria rolled out the 3-month Isoniazid-Rifampicin (3HR) shorter regimen TPT as a pilot for use among eligible adult and child contacts. This study assesses acceptance and completion rates of 3HR TPT among contacts and determines the perspectives of healthcare workers (HCWs) and contacts on acceptance and completion of 3HR TPT in Nigeria. In this cross-sectional descriptive study using mixed methods, records of TPT-eligible clients were retrospectively reviewed, while 18 purposely selected HCWs and 18 contacts on 3HR were interviewed. Of the 30,012 eligible contacts, 12,040 (40.1%) were initiated on TPT. Among these, 8213 (68%) were enrolled on 3HR, and 6972 (84.7%) of them completed treatment. Perceived facilitators include belief in its effectiveness, training among HCWs, and a good understanding of TPT from HCW counseling sessions. Barriers reported were linked to stockouts, misconceptions about side effects, non-disclosures, and disincentive follow-up strategies. The acceptance and completion rate for 3HR TPT was good. Scaling up 3HR TPT will require redesigning policies towards addressing identified barriers and utilizing interventions linked to capabilities, opportunities, and motivations among contacts of TB patients and HCWs.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Snakebites in Cameroon by Species Whose Effects Are Poorly Described.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-06 DOI: 10.3390/tropicalmed9120300

Jean-Philippe Chippaux, Yoann Madec, Pierre Amta, Rodrigue Ntone, Gaëlle Noël, Pedro Clauteaux, Yap Boum, Armand S Nkwescheu, Fabien Taieb

{"title":"Snakebites in Cameroon by Species Whose Effects Are Poorly Described.","authors":"Jean-Philippe Chippaux, Yoann Madec, Pierre Amta, Rodrigue Ntone, Gaëlle Noël, Pedro Clauteaux, Yap Boum, Armand S Nkwescheu, Fabien Taieb","doi":"10.3390/tropicalmed9120300","DOIUrl":"10.3390/tropicalmed9120300","url":null,"abstract":"Snakes responsible for bites are rarely identified, resulting in a loss of information about snakebites from venomous species whose venom effects are poorly understood. A prospective clinical study including patients bitten by a snake was conducted in Cameroon between 2019 and 2021 to evaluate the efficacy and tolerability of a marketed polyvalent antivenom. Clinical presentation during the first 3 days of hospitalization was recorded following a standardized protocol. This ancillary study aimed to assess the frequency of bites by the different species encountered in Cameroon and to describe the symptoms of bites by formally identified species. Of the 447 patients included in the study, 159 (35.6%) brought the snake that caused the bite that was identified by a specialist. Out of these, 8 specimens could not be identified due to poor condition, 19 were non-venomous species, and 95 belonged to Echis romani-formerly E. ocellatus-species. The remaining 37 specimens included 2 Atheris squamigera, 12 Atractaspis spp., 2 Bitis arietans, 11 Causus maculatus, 1 Dendroaspis jamesoni, 1 Naja haje, 1 N. katiensis, 5 N. melanoleuca complex, and 2 N. nigricollis. Symptoms, severity of envenomation, and post-treatment course are described. Symptoms and severity of bites are consistent with cases described in the literature, but some specific features are highlighted.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlates of Trachoma Recrudescence: Results from 51 District-Level Trachoma Surveillance Surveys in Amhara, Ethiopia.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-05 DOI: 10.3390/tropicalmed9120298

Eshetu Sata, Nicholas A Presley, Phong Le, Andrew W Nute, Zebene Ayele, Ayalew Shiferaw, Demelash Gessese, Ambahun Chernet, Berhanu Melak, Tania A Gonzalez, Kimberly A Jensen, Adisu Abebe Dawed, Taye Zeru, Zerihun Tadesse, Elizabeth Kelly Callahan, Scott D Nash

{"title":"Correlates of Trachoma Recrudescence: Results from 51 District-Level Trachoma Surveillance Surveys in Amhara, Ethiopia.","authors":"Eshetu Sata, Nicholas A Presley, Phong Le, Andrew W Nute, Zebene Ayele, Ayalew Shiferaw, Demelash Gessese, Ambahun Chernet, Berhanu Melak, Tania A Gonzalez, Kimberly A Jensen, Adisu Abebe Dawed, Taye Zeru, Zerihun Tadesse, Elizabeth Kelly Callahan, Scott D Nash","doi":"10.3390/tropicalmed9120298","DOIUrl":"10.3390/tropicalmed9120298","url":null,"abstract":"Trachoma recrudescence is a serious concern for trachoma control programs. Programs define recrudescence as the return of trachomatous inflammation-follicular (TF) prevalence above elimination threshold (≥5%) on district-level trachoma surveillance surveys (TSSs). This study aimed to determine potential correlates of trachoma recrudescence within a historically highly endemic region. Between 2015 and 2021, population-based TSSs were conducted in 51 districts of Amhara, Ethiopia. District estimates were calculated accounting for multistage design; logistic regression was used to estimate the association of key correlates with recrudescence at the district level. Among the 51 districts, 17 (33%) were recrudescent. Correlates of recrudescence included indicators of historic trachoma burden, such as higher trachomatous inflammation-intense (TI) prevalence (odds ratio [OR]: 2.6, CI: 1.4-5.3) and higher Chlamydia trachomatis (Ct) infection prevalence (OR: 2.9, CI: 1.1-9.9) at the first recorded impact survey. The increased prevalence of children with clean faces (OR: 0.4, CI: 0.21-1.0) and the increased prevalence of travel time to a water source ≤ 30 min (OR: 0.5, CI: 0.2-1.1) at the TSS were associated with a protective effect from recrudescence. Data on historical trachoma burden as well as current water and sanitation conditions may help programs predict where recrudescence is more likely to occur and thus help programs sustain elimination as a public health problem.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Paper to Digital: Performance and Challenges of the Electronic Hepatitis B Surveillance System in Ninh Binh, Northern Vietnam (2017-2022).

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-05 DOI: 10.3390/tropicalmed9120299

Hien T Nguyen, Thai Q Pham, Duc M Hoang, Quang D Tran, Giang T Chu, Thuong T Nguyen, Nam H Le, Huyen T Nguyen, Khanh C Nguyen, Florian Vogt

{"title":"From Paper to Digital: Performance and Challenges of the Electronic Hepatitis B Surveillance System in Ninh Binh, Northern Vietnam (2017-2022).","authors":"Hien T Nguyen, Thai Q Pham, Duc M Hoang, Quang D Tran, Giang T Chu, Thuong T Nguyen, Nam H Le, Huyen T Nguyen, Khanh C Nguyen, Florian Vogt","doi":"10.3390/tropicalmed9120299","DOIUrl":"10.3390/tropicalmed9120299","url":null,"abstract":"Hepatitis B remains a major public health issue in Vietnam. Mandatory reporting to the national electronic communicable disease surveillance system (eCDS) has been required since July 2016. We conducted an evaluation of the hepatitis B surveillance system in Ninh Binh, the province with the highest reported burden of hepatitis B in Northern Vietnam, between 2017 and 2022. Using the CDC's guidelines for evaluating public health surveillance systems, we assessed four key attributes: simplicity, timeliness, data quality, and acceptability. This retrospective evaluation included document reviews, analysis of hepatitis B data, and in-depth interviews with provincial-level healthcare staff involved in the reporting of hepatitis B cases. The results showed that the eCDS improved reporting frequency, provided more detailed case information, and enhanced data accessibility compared to the previous paper-based system. However, the system faced several challenges, including unclear objectives, difficulties in distinguishing acute from chronic cases, insufficient training for staff, lack of supervision for data quality, and technical software issues. Despite these challenges, stakeholders found the system acceptable but emphasized the need for improvements, including revising the system's objectives, automating case classification, enhancing training, securing funding for maintenance, and implementing regular data review processes.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transitioning Adolescents to Adult HIV Care in the United States: Implementation Lessons from the iTransition Intervention Pilot Trial.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-03 DOI: 10.3390/tropicalmed9120297

Amanda E Tanner, Sulianie Mertus, Mohammed Sheikh Eldin Jibriel, Rakira Urquhart, Keenan Phillips, Nadia Dowshen, Srija Dutta, Madeleine H Goldstein, Susan Lee, Kayla Knowles, Kaja Darien, Kelly L Rulison, Julia Madden, Sophia A Hussen

{"title":"Transitioning Adolescents to Adult HIV Care in the United States: Implementation Lessons from the iTransition Intervention Pilot Trial.","authors":"Amanda E Tanner, Sulianie Mertus, Mohammed Sheikh Eldin Jibriel, Rakira Urquhart, Keenan Phillips, Nadia Dowshen, Srija Dutta, Madeleine H Goldstein, Susan Lee, Kayla Knowles, Kaja Darien, Kelly L Rulison, Julia Madden, Sophia A Hussen","doi":"10.3390/tropicalmed9120297","DOIUrl":"10.3390/tropicalmed9120297","url":null,"abstract":"Although every youth in pediatric/adolescent HIV care will need to transition to adult-oriented care, there are no existing evidence-based interventions to optimize health through this process. Healthcare transition poses a persistent challenge to the health of youth living with HIV, which may result in gaps in care engagement, medication adherence, and viral suppression. Our process evaluation of iTransition, a multilevel mobile health (mHealth) intervention, included iterative interviews with youth, providers, and Transition Champions. These data, along with team meeting notes, highlight the important role the intervention plays in addressing healthcare transition-related challenges, positioning it to fill a critical gap for both youth and providers. It also highlights important individual (e.g., competing priorities of youth and providers), clinical (e.g., electronic health record integration), and contextual (e.g., clinical policies during COVID-19 pandemic) challenges to intervention reach and implementation. More work is needed to refine interventions to support care continuity for youth living with HIV as they transition to adult-oriented care.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142897780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burden of Food-Borne Trematodiases in China: Trends from 1990 to 2021 and Projections to 2035.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-03 DOI: 10.3390/tropicalmed9120295

Yanzheng Zou, Yihu Lin, Yili Qian, Luqiu Tao, Gao Tan, Hongru Zhu, Li Pan, Xiaoli Liu, Yu He, Wei Wang

{"title":"Burden of Food-Borne Trematodiases in China: Trends from 1990 to 2021 and Projections to 2035.","authors":"Yanzheng Zou, Yihu Lin, Yili Qian, Luqiu Tao, Gao Tan, Hongru Zhu, Li Pan, Xiaoli Liu, Yu He, Wei Wang","doi":"10.3390/tropicalmed9120295","DOIUrl":"10.3390/tropicalmed9120295","url":null,"abstract":"To assess the burden of food-borne trematodiases in China from 1990 to 2021 and project the burden through 2035, data were captured from the Global Burden of Disease Study (GBD) 2021 datasets. The estimated prevalent food-borne trematodiase cases were 33.32 million (95% uncertainty interval (UI): 29.25-38.35 million) in China in 2021, contributing to 768,297.4 disability-adjusted life years (DALYs) (95% UI: 383,882.8-1,367,826.1). The number of prevalent cases and DALYs declined by 9.02% and 18.11%, and a downward decline was seen in age-standardized prevalence and DALY rates (estimated annual percentage change: -0.96% and -1.21%, respectively). A higher prevalence and DALY rates were observed among males than females, and the middle-aged group bore the highest burden, while the older population showed the most rapid increase in prevalent cases and DALY numbers. Projected DALY counts and rates remain stable through 2035 using the Bayesian age-period-cohort (BAPC) model. These findings demonstrate a decline in the burden of food-borne trematodiases in China from 1990 to 2021; however, the prevalence remained high, which contributed considerably to disability and premature death. Continued control efforts and targeted interventions are essential to further reducing the burden of food-borne trematodiases in China.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating Community Engagement in Zero Leprosy Efforts: A Pathway to Sustainable Early Detection, Control and Elimination.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-03 DOI: 10.3390/tropicalmed9120296

Anil Fastenau, Matthew Willis, Constanze Vettel, Sophie C W Stuetzle, Srilekha Penna, Priyanka Chahal, Fabian Schlumberger, Mowmita Basak Mow, Ngozi Ekeke, Joseph Ngozi Chukwu, Patricia D Deps

{"title":"Integrating Community Engagement in Zero Leprosy Efforts: A Pathway to Sustainable Early Detection, Control and Elimination.","authors":"Anil Fastenau, Matthew Willis, Constanze Vettel, Sophie C W Stuetzle, Srilekha Penna, Priyanka Chahal, Fabian Schlumberger, Mowmita Basak Mow, Ngozi Ekeke, Joseph Ngozi Chukwu, Patricia D Deps","doi":"10.3390/tropicalmed9120296","DOIUrl":"10.3390/tropicalmed9120296","url":null,"abstract":"Community engagement has emerged as a critical component in the effective control and elimination of neglected tropical diseases (NTDs), particularly in regions with persistent stigma and limited healthcare access. Drawing on case studies from Brazil, India, and Nigeria, this opinion piece explores how community-driven initiatives have successfully improved leprosy awareness, reduced stigma, and fostered early case detection and treatment adherence. The importance of culturally sensitive, inclusive approaches in health education and stigma reduction campaigns is highlighted, emphasizing the potential for community engagement to enhance national leprosy programs and contribute to the World Health Organization's Zero Leprosy Strategy. By examining these examples, this article illustrates how integrating community participation into leprosy control and elimination programs can drive sustainable outcomes for achieving Zero Leprosy, even in resource-limited settings.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Trend of Tuberculosis Case Notification Rates from 1995 to 2022 by Country Income and World Health Organization Region. 按国家收入和世界卫生组织地区分列的 1995 至 2022 年结核病病例通报率趋势。

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-12-02 DOI: 10.3390/tropicalmed9120294

Kobto G Koura, Anthony D Harries

{"title":"The Trend of Tuberculosis Case Notification Rates from 1995 to 2022 by Country Income and World Health Organization Region.","authors":"Kobto G Koura, Anthony D Harries","doi":"10.3390/tropicalmed9120294","DOIUrl":"10.3390/tropicalmed9120294","url":null,"abstract":"Over the past 27 years, three major global TB control strategies have been implemented, and it is important at this stage to evaluate their impact on tuberculosis (TB) case notification rates (CNRs). This study, therefore, analyzed TB CNR trends from 1995 to 2022 across 208 countries and islands, using data from the WHO Global TB Programme database. Countries were classified by income level and population size based on World Bank criteria. The analysis revealed significant disparities in TB CNRs across income groups: Low-income, lower-middle-income, and upper-middle-income countries consistently reported higher CNRs compared to high-income countries. Regional analysis further demonstrated notable variations influenced by both economic and geographical factors. These findings reaffirm the strong link between TB and poverty, underscoring the need for a holistic approach to combat the disease. Efforts must extend beyond enhancing health care access and delivery to addressing the social determinants that drive TB transmission and progression.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Study of Urinary Schistosomiasis in the Eastern Cape Province, South Africa.

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2024-11-30 DOI: 10.3390/tropicalmed9120293

Dominic Targema Abaver

{"title":"A Retrospective Study of Urinary Schistosomiasis in the Eastern Cape Province, South Africa.","authors":"Dominic Targema Abaver","doi":"10.3390/tropicalmed9120293","DOIUrl":"10.3390/tropicalmed9120293","url":null,"abstract":"Schistosomiasis is caused by infection with trematode flukes of the genus Schistosoma. More than 700 million people worldwide are estimated to be susceptible to infection. In sub-Saharan Africa, schistosomiasis is the second most widespread neglected tropical disease after malaria. This retrospective investigation evaluated the incidence and impacts of schistosomiasis on communities across three major districts of the Eastern Cape province in South Africa using a cross-sectional retrospective observational analysis of secondary data from patients with microscopically confirmed schistosomiasis between 2019 and 2020. This study focused upon both rural and semi-urban areas, including Bizana, Butterworth, Centane, Elliotdale, Flagstaff, Idutywa, Lusikisiki, Libode, Mqanduli, Port St. Johns, Willowvale, and Mthatha. Data were obtained from three districts-Alfred Nzo, Amatole, and OR Tambo-covering both rural and semi-urban regions. This study included patients of all ages who submitted urine samples for schistosomiasis testing in the specified districts. A simple random sampling method was used to select 337 clinical records from the National Health Laboratory Service (NHLS) of Mthatha. Hospital records from the NHLS Microbiology Department of Mthatha were analyzed. St Barnabas Laboratory had the highest frequency of cases (34.1%), followed by Greenville Depot (17.8%) and Willowvale Laboratory (11.3%). Most cases were in the 10-19 age group (63.4%), followed by those under 10 years of age (24.9%). Male patients constituted 76.4% of the cases, while female patients accounted for 23.6%. Viable ova were observed in 98.2% of the samples. This study highlights a significant prevalence of schistosomiasis in the Eastern Cape province, with a higher incidence in rural areas and among males aged 10-19. These findings underscore the need for targeted public health interventions and continuous monitoring to control and prevent schistosomiasis in this region.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0