Tropical Medicine and Infectious Disease最新文献_第10页

Impact of Human Granulocytic Anaplasmosis in Spain from 1997 to 2022. 1997年至2022年西班牙人粒细胞无形体病的影响。

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-29 DOI: 10.3390/tropicalmed10070183

Hugo Almeida, Montserrat Alonso-Sardón, Beatriz Rodríguez-Alonso, Amparo López-Bernus, Ángela Romero-Alegría, Virginia Velasco-Tirado, Antonio Muro, Moncef Belhassen-García

{"title":"Impact of Human Granulocytic Anaplasmosis in Spain from 1997 to 2022.","authors":"Hugo Almeida, Montserrat Alonso-Sardón, Beatriz Rodríguez-Alonso, Amparo López-Bernus, Ángela Romero-Alegría, Virginia Velasco-Tirado, Antonio Muro, Moncef Belhassen-García","doi":"10.3390/tropicalmed10070183","DOIUrl":"10.3390/tropicalmed10070183","url":null,"abstract":"Human granulocytic anaplasmosis (HGA) is an emerging zoonosis in Europe, with limited data available from Spain. This study aimed to quantify HGA cases in the Spanish National Health System over the last 26 years, assess its evolution, and evaluate the impact in terms of hospital stay and cost. A retrospective observational case series was conducted using the Minimal Basic Data Set (MBDS, CMBD in Spanish). Hospitalized patients with ICD-9-CM and ICD-10 codes for anaplasmosis from 1997 to 2022 were included. Ten HGA cases were reported. The incidence remained stable at one case per year [IR = 0.021 cases/million person-years], except in 2018 [IR = 0.048]. Six patients (60%) were men, with a mean age of 49 years (±20.9). Hospital stays ranged from 3 to 13 days. The total cost was EUR 45,540.57, with an average cost of EUR 4554.06 (±1032.16) per case. All patients had favorable outcomes. HGA has a low incidence in Spain, with moderate associated costs. Despite its emergence, its economic and health impact remains manageable, underscoring the effectiveness of Spain's healthcare system. Continued surveillance and prevention are essential to address evolving vector-borne diseases.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12298059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential Emodepside Efficacy in Drug-Resistant and Drug-Susceptible Ancylostoma caninum Highlights Variability in Potassium Channel Activity. 地黄苷在耐药和药敏犬钩虫中的不同疗效突出了钾通道活性的变异性。

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-27 DOI: 10.3390/tropicalmed10070181

Catherine A Jackson, Elise L McKean, John M Hawdon

{"title":"Differential Emodepside Efficacy in Drug-Resistant and Drug-Susceptible Ancylostoma caninum Highlights Variability in Potassium Channel Activity.","authors":"Catherine A Jackson, Elise L McKean, John M Hawdon","doi":"10.3390/tropicalmed10070181","DOIUrl":"10.3390/tropicalmed10070181","url":null,"abstract":"Multi-anthelmintic resistance in hookworms poses a significant challenge to both human and veterinary health, underscoring the need for novel treatment strategies. In this study, we evaluated the in vitro efficacy of three anthelmintics-pyrantel, ivermectin, and emodepside-against L3 larvae of drug-susceptible (WMD) and triple-anthelmintic-resistant (BCR) isolates of Ancylostoma caninum. While pyrantel was largely ineffective and ivermectin induced high mortality in both isolates, emodepside displayed a surprising trend: the drug-resistant BCR isolate was more susceptible than the drug-susceptible WMD isolate. To explore the underlying mechanism, we performed survival assays in the presence of penitrem A, a BK channel (SLO-1) inhibitor. The addition of penitrem A reversed the enhanced emodepside sensitivity in BCR, implicating elevated basal expression of SLO-1 channels as a potential factor. These findings suggest that emodepside, via its action on SLO-1, may offer a promising therapeutic avenue to combat multidrug-resistant hookworm infections.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First Report of the L925I kdr Mutation Associated with Pyrethroid Resistance in Genetically Distinct Triatoma dimidiata, Vector of Chagas Disease in Mexico. 墨西哥恰加斯病传播媒介L925I kdr突变与拟除虫菊酯抗性相关的首次报道

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-27 DOI: 10.3390/tropicalmed10070182

Mario C Saucedo-Montalvo, Jesus A Davila-Barboza, Selene M Gutierrez-Rodriguez, Beatriz Lopez-Monroy, Susana Favela-Lara, Iram P Rodriguez-Sanchez, Guadalupe Del C Reyes-Solis, Cristina Bobadilla-Utrera, Adriana E Flores

{"title":"First Report of the L925I kdr Mutation Associated with Pyrethroid Resistance in Genetically Distinct Triatoma dimidiata, Vector of Chagas Disease in Mexico.","authors":"Mario C Saucedo-Montalvo, Jesus A Davila-Barboza, Selene M Gutierrez-Rodriguez, Beatriz Lopez-Monroy, Susana Favela-Lara, Iram P Rodriguez-Sanchez, Guadalupe Del C Reyes-Solis, Cristina Bobadilla-Utrera, Adriana E Flores","doi":"10.3390/tropicalmed10070182","DOIUrl":"10.3390/tropicalmed10070182","url":null,"abstract":"Triatoma dimidiata is a widely distributed vector of Trypanosoma cruzi in Mexico and Central America, found across a range of habitats from sylvatic to domestic. Vector control has relied heavily on indoor residual spraying with pyrethroids; however, reinfestation and emerging resistance have limited its long-term effectiveness. In this study, we analyzed the genetic diversity and population structure of T. dimidiata from Veracruz, Oaxaca, and Yucatan using mitochondrial markers (cyt b and ND4) and screened for knockdown resistance (kdr)-type mutations in the voltage-gated sodium channel (VGSC) gene. High haplotype diversity and regional differentiation were observed, with most genetic variation occurring between populations. The ND4 marker provided greater resolution than cyt b, revealing ten haplotypes and supporting evidence of recent population expansion. Haplotype networks showed clear geographic segregation, particularly between populations east and west of the Isthmus of Tehuantepec. The L925I mutation, highly associated with pyrethroid resistance, was detected for the first time in Mexican populations of T. dimidiata, albeit at low frequencies. These findings highlight the importance of integrating population genetic data and resistance surveillance into regionally adapted vector control strategies for Chagas disease.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12299954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global Trends and Attributable Risk Factors in the Disease Burden of Lower Respiratory Infections. 下呼吸道感染疾病负担的全球趋势和归因危险因素。

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-26 DOI: 10.3390/tropicalmed10070180

E Yu, Chunhui Li

{"title":"Global Trends and Attributable Risk Factors in the Disease Burden of Lower Respiratory Infections.","authors":"E Yu, Chunhui Li","doi":"10.3390/tropicalmed10070180","DOIUrl":"10.3390/tropicalmed10070180","url":null,"abstract":"Background: Lower respiratory infections (LRIs) are the leading cause of the global disease burden, accounting for millions of deaths each year.Methods: Data on LRIs, including deaths, disability-adjusted life years (DALYs), and incidence, were obtained from the Global Burden of Disease Study 2021. Joinpoint regression was employed to assess temporal trends in the LRIs' burden, while the age-period-cohort model was used to evaluate age, period, and cohort effects. Pearson's correlation coefficients were calculated to examine the relationship between DALYs attributable to risk factors and the socio-demographic index (SDI).Results: Over recent decades, the average annual percentage change in age-standardized mortality rate, age-standardized DALYs rate, and age-standardized incidence rate of LRIs globally were -2.4%, -3.5%, and -1.3%, respectively. Notably, the LRIs' burden dropped considerably from 2019 to 2021. The disease burden was higher among children under five and individuals over 60 compared to other age groups. In terms of gender, males had a higher burden. The age-standardized DALYs rate of LRIs was strongly and negatively correlated with SDI (r = -0.84; p < 0.05). Streptococcus pneumoniae remained the leading pathogen, followed by Staphylococcus aureus, and Klebsiella pneumoniae.Conclusions: In recent years, the global burden of LRIs has declined, but regional, gender, and age disparities persist. Targeted measures are needed to address high-risk populations and major risk factors.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12300696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occupational Syndemics in Farmworkers in the Cape Winelands, South Africa. 南非开普酒地农场工人的职业综合症。

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-24 DOI: 10.3390/tropicalmed10070179

Nicola Bulled

{"title":"Occupational Syndemics in Farmworkers in the Cape Winelands, South Africa.","authors":"Nicola Bulled","doi":"10.3390/tropicalmed10070179","DOIUrl":"10.3390/tropicalmed10070179","url":null,"abstract":"Occupational exposures in the agricultural industry globally have been associated with heightened risk for several diseases. Reports written in South Africa in the last decade have raised awareness of the harsh occupational conditions and human rights abuses suffered by farmworker communities in the wine industry. Despite receiving \"fair trade\" labels upon reentry into the global market in the 1990s, the working conditions on wine farms in South Africa have remained unchanged and exploitative for centuries. Farmworkers remain dependent on substandard farm housing, have insecure land tenure rights, are exposed to toxic pesticides, are denied access to benefits and unionization, and endure long working hours in harsh environmental conditions with low pay. These occupational conditions are linked to interacting disease clusters: metabolic syndrome, problematic drinking, and communicable diseases including tuberculosis, HIV, and COVID-19. This milieu of interacting diseases with deleterious outcomes is an under-considered occupational syndemic that will likely worsen given both the lasting impacts of COVID-19 and more recent shifts in global public health funding.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12299630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTED: Jang, S.; Sohn, A. Awareness, Intention to Use Pre-Exposure Prophylaxis, and Factors Associated with Awareness among Men Who Have Sex with Men in the Republic of Korea. Trop. Med. Infect. Dis. 2024, 9, 170. 撤稿：Jang， S.；韩国男男性行为者的意识、使用暴露前预防措施的意愿以及与意识相关的因素。太。地中海,感染。[j] . 2024, 9,170。

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-23 DOI: 10.3390/tropicalmed10070178

Sarang Jang, Aeree Sohn

引用次数: 0

Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization. lagochil蛔虫病：在巴西亚马逊生物群被忽视的人畜共患病和野生动物在其流行病学链中的作用。

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-21 DOI: 10.3390/tropicalmed10070177

Felipe Masiero Salvarani, Karoline Petrini Pinheiro da Cruz, Flavio Roberto Chaves da Silva, Cíntia Daudt

{"title":"Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization.","authors":"Felipe Masiero Salvarani, Karoline Petrini Pinheiro da Cruz, Flavio Roberto Chaves da Silva, Cíntia Daudt","doi":"10.3390/tropicalmed10070177","DOIUrl":"10.3390/tropicalmed10070177","url":null,"abstract":"Lagochilascariasis is a neglected zoonotic helminthiasis, caused by Lagochilascaris minor, characterized by a complex and not well understood transmission cycle. This parasitic disease is endemic to Latin America, particularly Brazil, and is associated with rural and forested areas, where humans may serve as accidental hosts. The southeastern region of Pará state reports the highest number of cases, highlighting its epidemiological significance. Wildlife species, especially carnivores and rodents, play crucial roles as definitive and intermediate hosts, respectively. Although lagochilascariasis can lead to severe clinical manifestations, including chronic soft tissue infections and potential central nervous system involvement, it is likely underdiagnosed due to its similarity to fungal and bacterial diseases. The anthropization of the Amazon Biome, through deforestation and habitat fragmentation, coupled with increased human-wildlife interactions, may be influencing the epidemiology of this parasitosis. This review aims to summarize current knowledge of L. minor transmission routes, the role of wildlife in maintaining its cycle, and the impact of environmental changes on disease patterns. Such insights are vital for One Health strategies, which integrate human, animal, and environmental health approaches to mitigate the disease burden.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12299052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Social and Clinical Factors Associated with Adverse Drug Reactions Among Children with Drug-Resistant Tuberculosis in Pakistan. 巴基斯坦耐药结核病儿童药物不良反应相关社会和临床因素评价

IF 2.6 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-20 DOI: 10.3390/tropicalmed10070176

Muhammad Soaib Said, Razia Fatima, Rabbiya Ahmad, Mahmood Basil A Al Rawi, Faheem Jan, Sobia Faisal, Irfanullah Khan, Amer Hayat Khan

{"title":"Evaluation of Social and Clinical Factors Associated with Adverse Drug Reactions Among Children with Drug-Resistant Tuberculosis in Pakistan.","authors":"Muhammad Soaib Said, Razia Fatima, Rabbiya Ahmad, Mahmood Basil A Al Rawi, Faheem Jan, Sobia Faisal, Irfanullah Khan, Amer Hayat Khan","doi":"10.3390/tropicalmed10070176","DOIUrl":"10.3390/tropicalmed10070176","url":null,"abstract":"(1) Background: The occurrence, intensity, and characteristics of adverse drug reactions (ADRs) caused by anti-tuberculosis (TB) drugs have consistently been a subject of worry. There is a lack of published research from Pakistan regarding the negative effects of anti-TB treatment on children, specifically about ADRs. In this study, we aimed to investigate the ADR associated with anti-DR-TB treatment in children. (2) Methods: A prospective longitudinal study was conducted in the multicenter setting of Khyber Pakhtunkhwa, Pakistan. A total of 450 TB children in multicenter hospitals under ATT were assessed for ADRs. Naranjo Causality Assessment and Hartwig's Severity Assessment Scale were used to evaluate the causality and severity. (3) Results: A total of 300 (66.66%) ADRs were reported in 450 people with DRTB. Anemia was the most frequently observed ADR (37.6%) followed by nausea and vomiting (18.6%). On multivariate analysis, the independent variables that had a statistically significant positive association with ADRs were participants aged, 5-14 years (AOR, 0.3 (0.1-0.5), p ≤ 0.001), normal weight (1.1 (2.0-1.9), p < 0.001), and children having comorbidities (AOR, 0.5 (0.1-0.8), p ≤ 0.001). (4) Conclusions: Our findings advocate for personalized treatment approaches, incorporating nutritional support, comprehensive comorbidity management, and vigilant monitoring to mitigate ADRs and improve treatment outcomes.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 7","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12299254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistence of Untreated Bed Nets in the Retail Market in Tanzania: A Cross-Sectional Survey. 未经处理的蚊帐在坦桑尼亚零售市场的持久性：一项横断面调查。

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-19 DOI: 10.3390/tropicalmed10060175

Benjamin Kamala, Dana Loll, Ruth Msolla, David Dadi, Peter Gitanya, Charles Mwalimu, Frank Chacky, Stella Kajange, Mwinyi Khamis, Sarah-Blythe Ballard, Naomi Serbantez, Stephen Poyer

{"title":"Persistence of Untreated Bed Nets in the Retail Market in Tanzania: A Cross-Sectional Survey.","authors":"Benjamin Kamala, Dana Loll, Ruth Msolla, David Dadi, Peter Gitanya, Charles Mwalimu, Frank Chacky, Stella Kajange, Mwinyi Khamis, Sarah-Blythe Ballard, Naomi Serbantez, Stephen Poyer","doi":"10.3390/tropicalmed10060175","DOIUrl":"10.3390/tropicalmed10060175","url":null,"abstract":"The private sector in Tanzania has played an essential role in improving coverage and access to mosquito nets. This follow-up study assessed the overall market share for untreated and insecticide-treated nets (ITNs) and misleading or counterfeit ITN products in commercial markets. This study was conducted from March to April 2024 in ten regions in Tanzania. The study used mixed methods: (1) a quantitative survey among sampled outlets supported by photographic documentation of all net products and (2) key informant interviews of retailers and wholesalers. We assessed the relationship between market share and population access using ANOVA and Pearson correlation. No counterfeit or misleading nets were found, consistent with results from 2017, 2021, and 2022 surveys. Untreated nets dominated all markets, comprising 99% of all products observed and 99% of estimated net sales 3 months before the survey. Legitimate ITNs were crowded out from the studied markets. Leaked nets from free distributions were present but extremely limited (1%) and at their lowest level of the survey rounds. Untreated nets were more expensive than leaked ITNs for both regular- and queen-size nets. Despite ongoing efforts, increasing the share of legitimate ITNs remains a significant challenge in a context of large-scale public sector distributions.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12197522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 2.8 4区医学

Tropical Medicine and Infectious Disease Pub Date : 2025-06-18 DOI: 10.3390/tropicalmed10060174

Laetitia Ferraro, Sébastien Briolant, Mathieu Nacher, Samuel Vezenegho, Antoine Adde, Christophe Nguyen, Pascal Gaborit, Jean Issaly, Romuald Carinci, Vincent Pommier de Santi, Romain Girod, Isabelle Dusfour, Hervé Bogreau

{"title":"Similar Microsatellite Allelic Distribution Between Anopheles darlingi Population Collected by Human Landing Catch or Mosquito Magnet Traps in French Guiana.","authors":"Laetitia Ferraro, Sébastien Briolant, Mathieu Nacher, Samuel Vezenegho, Antoine Adde, Christophe Nguyen, Pascal Gaborit, Jean Issaly, Romuald Carinci, Vincent Pommier de Santi, Romain Girod, Isabelle Dusfour, Hervé Bogreau","doi":"10.3390/tropicalmed10060174","DOIUrl":"10.3390/tropicalmed10060174","url":null,"abstract":"Anopheles darlingi is a major malaria vector in South America. Understanding its population dynamics is critical for designing effective vector control strategies. While various Anopheles collection methods exist, they may sample distinct populations. Microsatellite genotyping across nine loci was performed to characterize An. darlingi populations, which were collected in French Guiana between 6:30 p.m. and 7:00 a.m. using human landing catch (HLC) or Mosquito Magnet® (MM) traps. Traps were arranged in a 3 × 3 Latin square design to minimize possible effects of geographical position. Pairwise FST index and discriminant analyses of principal components (DAPC) were used to make comparisons. A total of 431 An. darlingi were analyzed. No significant genetic differentiation was observed between collection methods or time slots (FST values non-significant, p > 0.25), with DAPC revealing a single genetic cluster. Despite documented phenotypic variations, no significant population structure was detected among An. darlingi sampled in a rural village in French Guiana via collection methods or time slots. These findings confirm that mosquitoes collected with these various methods or time slots are suitable for the molecular studies of An. darlingi in French Guiana. In this context, Mosquito Magnet® traps could also represent an alternative to the now controversial human landing catch.","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"10 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12197347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0