Tropical Medicine and Infectious Disease最新文献

{"title":"Cross-Resistance to Pyrethroids and Neonicotinoids in Malaria Vectors from Vegetable Farms in the Northern Benin.","authors":"Massioudou Koto Yérima Gounou Boukari, Innocent Djègbè, Ghislain T Tepa-Yotto, Donald Hessou-Djossou, Genevieve Tchigossou, Eric Tossou, Michel Lontsi-Demano, Danahé Adanzounon, Adam Gbankoto, Luc Djogbénou, Rousseau Djouaka","doi":"10.3390/tropicalmed9120305","DOIUrl":"10.3390/tropicalmed9120305","url":null,"abstract":"<p><p>Agricultural pesticides may play a crucial role in the selection of resistance in field populations of mosquito vectors. This study aimed to determine the susceptibility level of <i>An. gambiae</i> s.l. to pyrethroids and neonicotinoids in vegetable farms in northern Benin, in West Africa, and the underlying insecticide resistance mechanisms. A survey on agricultural practices was carried out on 85 market gardeners chosen randomly in Malanville and Parakou. <i>Anopheles gambiae</i> s.l. larvae were collected, reared to adult stages, and identified to species level. Susceptibility was tested with impregnated papers (WHO bioassays) or CDC bottles according to the insecticides. Synergists (PBO, DEM, and DEF) were used to screen resistance mechanisms. Allelic frequencies of the <i>kdr (L1014F)</i>, <i>kdr (L1014S)</i>, <i>N1575Y</i>, and <i>ace-1R G119S</i> mutations were determined in mosquitoes using Taqman PCR. Fertilizers and pesticides were the agrochemicals most used with a rate of 97.78% and 100%, respectively, in Malanville and Parakou. <i>Anopheles coluzzii</i> was the predominant species in Malanville, while <i>An. gambiae</i> was the only species found in Parakou. Bioassays revealed a high resistance of <i>An. gambiae</i> s.l. to pyrethroids and DDT, while a susceptibility to bendiocarb, pyrimiphos-methyl, malathion, and clothianidin was recorded. Resistance to acetamiprid was suspected in mosquitoes from both localities. A lower resistance level was observed when mosquitoes were pre-treated with synergists, then exposed to insecticides. The <i>kdr L1014F</i> mutation was observed in both locations at moderate frequencies (0.50 in Malanville and 0.55 in Parakou). The allelic frequencies of <i>N1575Y</i> and <i>G119S</i> were low in both study sites. This study confirmed the resistance of <i>An. gambiae</i> s.l. to insecticides used in agriculture and public health. It reveals a susceptibility of vectors to bendiocarb, pyrimiphos-methyl, malathion, and clothianidin, thus indicating that these insecticides can be used as an alternative in Benin to control malaria vectors.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inclusion of Labor Migrants as a Potential Key Population for HIV: A Nationwide Study from Tajikistan.","authors":"Brian Kwan, Hamid R Torabzadeh, Adebimpe O Akinwalere, Julie Nguyen, Patricia Cortez, Jamoliddin Abdullozoda, Salomudin J Yusufi, Kamiar Alaei, Arash Alaei","doi":"10.3390/tropicalmed9120304","DOIUrl":"10.3390/tropicalmed9120304","url":null,"abstract":"<p><p>Key populations are particularly vulnerable to human immunodeficiency virus (HIV) infection. Nearly half of Tajikistan's gross domestic product (GDP) originates from labor migrant transfers. While not officially designated as a key population, over 300,000 migrants return to Tajikistan every year at increased risk for HIV due to absence or interruption of treatment, change in risky behaviors, and other factors. We analyzed cross-sectional data from the national registry system operated by the Tajikistan Ministry of Health and Social Protection of individuals (<i>n</i> = 10,700) who had been diagnosed with HIV from 1 January 2010 to 30 May 2023. Individual HIV cases resided in five regions: Districts of Republican Subordination (DRS), Dushanbe (Tajikistan's capital city), Gorno-Badakhshan Autonomous Oblast (GBAO), Khatlon, and Sughd. We developed logistic regression models to investigate the relationships between key population status and demographic characteristics. GBAO has the largest proportion of labor migrants (49.59%), which is much larger than that of the other regions (<32%). In contrast to other key populations, there was a larger proportion of HIV cases in rural areas that were labor migrants (23.25%) in comparison to urban areas (16.05%). In multivariable analysis, the odds of being a labor migrant were 6.248 (95% CI: 4.811, 8.113), 2.691 (95% CI: 2.275, 3.184), and 1.388 (95% CI: 1.155, 1.668) times larger if a case was residing in GBAO, Sughd, or DRS, compared to Dushanbe, respectively. Our research contributes to the field by proposing to expand the definition of key population to include labor migrants in Central Asia who should be emphasized as a vulnerable population at high risk of HIV. We encourage policy action to provide designated HIV funding for labor migrants, increase international attention, and promote potential modifications of national regulations and/or laws regarding prevention and treatment of HIV among non-citizen populations.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abundance and Distribution of <i>Phlebotomus pedifer</i> (Diptera: Psychodidae) Across Various Habitat Types in Endemic Foci of Cutaneous Leishmaniasis in the Mid-Highlands of Wolaita Zone, Southern Ethiopia.","authors":"Bereket Alemayehu, Temesgen Tomas, Negese Koroto, Teshome Matusala, Aberham Megaze, Herwig Leirs","doi":"10.3390/tropicalmed9120302","DOIUrl":"10.3390/tropicalmed9120302","url":null,"abstract":"<p><p><i>Phlebotomus pedifer</i> is a vector of <i>Leishmania aethiopica</i>, the causative agent of cutaneous leishmaniasis. This study assessed the abundance and distribution of <i>P. pedifer</i> in different habitats and human houses situated at varying distances from hyrax (reservoir host) dwellings, in Wolaita Zone, southern Ethiopia. Sandflies were collected from January 2020 to December 2021 using CDC light traps, sticky paper traps, and locally made emergence traps. Sampling was performed in human houses, peri-domestic areas, farmlands, and hyrax dwellings. Houses 200 m and 400 m from hyrax dwellings were selected to study whether distance affects indoor sandfly abundance. A total of 2485 sandflies were captured, with <i>P. pedifer</i> accounting for 86.1% of the catch and <i>Sergentomyia</i> spp. comprising the remaining 13.9%. The abundance of <i>P. pedifer</i> was highest in human houses (72.3%) and lowest in farmlands (4.0%). Temperature showed a positive correlation with sandfly abundance (r = 0.434, <i>p</i> = 0.000), while rainfall (r = -0.424, <i>p</i> = 0.001) and humidity (r = -0.381, <i>p</i> = 0.001) were negatively correlated with abundance. Houses near hyrax dwellings had significantly higher <i>P. pedifer</i> abundance compared to those further away. Soil-emergence trapping yielded only a few <i>P. pedifer</i> specimens, primarily from hyrax dwellings. The findings highlight the increased presence of <i>P. pedifer</i> indoors, particularly in houses close to hyrax habitats, emphasizing the need for targeted indoor vector control strategies to mitigate the risk of cutaneous leishmaniasis transmission.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micronutrient Biomarkers and Their Association with Malaria Infection in Children in Buea Health District, Cameroon.","authors":"Jerome Nyhalah Dinga, Emmanuel Fondungallah Anu, Romelle Dibanda Feumba, Haowen Qin, Flora Ayah, Rene Bilingwe Ayiseh, Robert Adamu Shey, Stanley Dobgima Gamua, Anthony Kukwah Tufon, Rameshbabu Manyam, Vincent P K Titanji","doi":"10.3390/tropicalmed9120303","DOIUrl":"10.3390/tropicalmed9120303","url":null,"abstract":"<p><p>Recently malaria and micronutrient deficiencies have become a major worldwide public health problem, particularly in Africa and other endemic countries with children under 5 years old being the most vulnerable. Apart from nutritional problems that cause micronutrient deficiencies, studies have also reported that parasitic infections like malaria can affect the levels of micronutrients. Thus, this research was aimed at assessing the serum levels of micronutrient biomarkers and their association with malaria infection in children under 5 years old in the Buea Health District. Method: This cross-sectional study recruited 80 participants from February to April 2024. The micronutrient biomarkers levels were measured using a Q-7plex Human Micronutrient Measurement Kit. Results: There were changes in serum micronutrient biomarkers levels between malaria infected and healthy children. Ferritin was higher in sick children (23.53 μg/L ± 7.75) than in healthy children (19.07 μg/L ± 3.87), significantly (<i>p</i> < 0.002). The same trend was observed with the soluble transferrin receptor being higher (<i>p</i> < 0.049) in sick children (3.74 mg/L ± 1.92) compared to healthy ones (3.08 mg/L ± 0.64). In addition, the levels of retinol-binding protein 4 and thyroglobulin levels were not significantly different between the sick and healthy children. Therefore, this study revealed that malaria causes alterations in the serum levels of micronutrient biomarkers and consequently affects micronutrient levels in children below the age of 5 in the Buea Health District.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptance and Completion Rates of 3-Month Isoniazid-Rifampicin (3HR) Tuberculosis Preventive Treatment (TPT) Among Contacts of Bacteriologically Confirmed TB Patients-Patients' and Healthcare Workers' Perspectives.","authors":"Austin Ihesie, Ogoamaka Chukwuogo, Rupert Eneogu, Olugbenga Kayode Daniel, Aderonke Agbaje, Bethrand Odume, Debby Nongo, Charles Ohikhuai, Nera Kadiri-Eneh, Omosalewa Oyelaran, Victor Obianeri, Wayne Van Gemert, Enos Okumu Masini, Cleophas D'auvergne, Urhioke Ochuko, Chukwuma Anyaike, Sunday Olakunle Olarewaju","doi":"10.3390/tropicalmed9120301","DOIUrl":"10.3390/tropicalmed9120301","url":null,"abstract":"<p><p>Providing tuberculosis preventive treatment (TPT) to close contacts of persons with TB is a core strategy recommended by WHO for the prevention and control of TB. Nigeria rolled out the 3-month Isoniazid-Rifampicin (3HR) shorter regimen TPT as a pilot for use among eligible adult and child contacts. This study assesses acceptance and completion rates of 3HR TPT among contacts and determines the perspectives of healthcare workers (HCWs) and contacts on acceptance and completion of 3HR TPT in Nigeria. In this cross-sectional descriptive study using mixed methods, records of TPT-eligible clients were retrospectively reviewed, while 18 purposely selected HCWs and 18 contacts on 3HR were interviewed. Of the 30,012 eligible contacts, 12,040 (40.1%) were initiated on TPT. Among these, 8213 (68%) were enrolled on 3HR, and 6972 (84.7%) of them completed treatment. Perceived facilitators include belief in its effectiveness, training among HCWs, and a good understanding of TPT from HCW counseling sessions. Barriers reported were linked to stockouts, misconceptions about side effects, non-disclosures, and disincentive follow-up strategies. The acceptance and completion rate for 3HR TPT was good. Scaling up 3HR TPT will require redesigning policies towards addressing identified barriers and utilizing interventions linked to capabilities, opportunities, and motivations among contacts of TB patients and HCWs.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Snakebites in Cameroon by Species Whose Effects Are Poorly Described.","authors":"Jean-Philippe Chippaux, Yoann Madec, Pierre Amta, Rodrigue Ntone, Gaëlle Noël, Pedro Clauteaux, Yap Boum, Armand S Nkwescheu, Fabien Taieb","doi":"10.3390/tropicalmed9120300","DOIUrl":"10.3390/tropicalmed9120300","url":null,"abstract":"<p><p>Snakes responsible for bites are rarely identified, resulting in a loss of information about snakebites from venomous species whose venom effects are poorly understood. A prospective clinical study including patients bitten by a snake was conducted in Cameroon between 2019 and 2021 to evaluate the efficacy and tolerability of a marketed polyvalent antivenom. Clinical presentation during the first 3 days of hospitalization was recorded following a standardized protocol. This ancillary study aimed to assess the frequency of bites by the different species encountered in Cameroon and to describe the symptoms of bites by formally identified species. Of the 447 patients included in the study, 159 (35.6%) brought the snake that caused the bite that was identified by a specialist. Out of these, 8 specimens could not be identified due to poor condition, 19 were non-venomous species, and 95 belonged to <i>Echis romani</i>-formerly <i>E. ocellatus</i>-species. The remaining 37 specimens included 2 <i>Atheris squamigera</i>, 12 <i>Atractaspis</i> spp., 2 <i>Bitis arietans</i>, 11 <i>Causus maculatus</i>, 1 <i>Dendroaspis jamesoni</i>, 1 <i>Naja haje</i>, 1 <i>N. katiensis</i>, 5 <i>N. melanoleuca</i> complex, and 2 <i>N. nigricollis</i>. Symptoms, severity of envenomation, and post-treatment course are described. Symptoms and severity of bites are consistent with cases described in the literature, but some specific features are highlighted.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of Trachoma Recrudescence: Results from 51 District-Level Trachoma Surveillance Surveys in Amhara, Ethiopia.","authors":"Eshetu Sata, Nicholas A Presley, Phong Le, Andrew W Nute, Zebene Ayele, Ayalew Shiferaw, Demelash Gessese, Ambahun Chernet, Berhanu Melak, Tania A Gonzalez, Kimberly A Jensen, Adisu Abebe Dawed, Taye Zeru, Zerihun Tadesse, Elizabeth Kelly Callahan, Scott D Nash","doi":"10.3390/tropicalmed9120298","DOIUrl":"10.3390/tropicalmed9120298","url":null,"abstract":"<p><p>Trachoma recrudescence is a serious concern for trachoma control programs. Programs define recrudescence as the return of trachomatous inflammation-follicular (TF) prevalence above elimination threshold (≥5%) on district-level trachoma surveillance surveys (TSSs). This study aimed to determine potential correlates of trachoma recrudescence within a historically highly endemic region. Between 2015 and 2021, population-based TSSs were conducted in 51 districts of Amhara, Ethiopia. District estimates were calculated accounting for multistage design; logistic regression was used to estimate the association of key correlates with recrudescence at the district level. Among the 51 districts, 17 (33%) were recrudescent. Correlates of recrudescence included indicators of historic trachoma burden, such as higher trachomatous inflammation-intense (TI) prevalence (odds ratio [OR]: 2.6, CI: 1.4-5.3) and higher <i>Chlamydia trachomatis</i> (<i>Ct</i>) infection prevalence (OR: 2.9, CI: 1.1-9.9) at the first recorded impact survey. The increased prevalence of children with clean faces (OR: 0.4, CI: 0.21-1.0) and the increased prevalence of travel time to a water source ≤ 30 min (OR: 0.5, CI: 0.2-1.1) at the TSS were associated with a protective effect from recrudescence. Data on historical trachoma burden as well as current water and sanitation conditions may help programs predict where recrudescence is more likely to occur and thus help programs sustain elimination as a public health problem.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Paper to Digital: Performance and Challenges of the Electronic Hepatitis B Surveillance System in Ninh Binh, Northern Vietnam (2017-2022).","authors":"Hien T Nguyen, Thai Q Pham, Duc M Hoang, Quang D Tran, Giang T Chu, Thuong T Nguyen, Nam H Le, Huyen T Nguyen, Khanh C Nguyen, Florian Vogt","doi":"10.3390/tropicalmed9120299","DOIUrl":"10.3390/tropicalmed9120299","url":null,"abstract":"<p><p>Hepatitis B remains a major public health issue in Vietnam. Mandatory reporting to the national electronic communicable disease surveillance system (eCDS) has been required since July 2016. We conducted an evaluation of the hepatitis B surveillance system in Ninh Binh, the province with the highest reported burden of hepatitis B in Northern Vietnam, between 2017 and 2022. Using the CDC's guidelines for evaluating public health surveillance systems, we assessed four key attributes: simplicity, timeliness, data quality, and acceptability. This retrospective evaluation included document reviews, analysis of hepatitis B data, and in-depth interviews with provincial-level healthcare staff involved in the reporting of hepatitis B cases. The results showed that the eCDS improved reporting frequency, provided more detailed case information, and enhanced data accessibility compared to the previous paper-based system. However, the system faced several challenges, including unclear objectives, difficulties in distinguishing acute from chronic cases, insufficient training for staff, lack of supervision for data quality, and technical software issues. Despite these challenges, stakeholders found the system acceptable but emphasized the need for improvements, including revising the system's objectives, automating case classification, enhancing training, securing funding for maintenance, and implementing regular data review processes.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transitioning Adolescents to Adult HIV Care in the United States: Implementation Lessons from the <i>iTransition</i> Intervention Pilot Trial.","authors":"Amanda E Tanner, Sulianie Mertus, Mohammed Sheikh Eldin Jibriel, Rakira Urquhart, Keenan Phillips, Nadia Dowshen, Srija Dutta, Madeleine H Goldstein, Susan Lee, Kayla Knowles, Kaja Darien, Kelly L Rulison, Julia Madden, Sophia A Hussen","doi":"10.3390/tropicalmed9120297","DOIUrl":"10.3390/tropicalmed9120297","url":null,"abstract":"<p><p>Although every youth in pediatric/adolescent HIV care will need to transition to adult-oriented care, there are no existing evidence-based interventions to optimize health through this process. Healthcare transition poses a persistent challenge to the health of youth living with HIV, which may result in gaps in care engagement, medication adherence, and viral suppression. Our process evaluation of <i>iTransition</i>, a multilevel mobile health (mHealth) intervention, included iterative interviews with youth, providers, and Transition Champions. These data, along with team meeting notes, highlight the important role the intervention plays in addressing healthcare transition-related challenges, positioning it to fill a critical gap for both youth and providers. It also highlights important individual (e.g., competing priorities of youth and providers), clinical (e.g., electronic health record integration), and contextual (e.g., clinical policies during COVID-19 pandemic) challenges to intervention reach and implementation. More work is needed to refine interventions to support care continuity for youth living with HIV as they transition to adult-oriented care.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142897780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of Food-Borne Trematodiases in China: Trends from 1990 to 2021 and Projections to 2035.","authors":"Yanzheng Zou, Yihu Lin, Yili Qian, Luqiu Tao, Gao Tan, Hongru Zhu, Li Pan, Xiaoli Liu, Yu He, Wei Wang","doi":"10.3390/tropicalmed9120295","DOIUrl":"10.3390/tropicalmed9120295","url":null,"abstract":"<p><p>To assess the burden of food-borne trematodiases in China from 1990 to 2021 and project the burden through 2035, data were captured from the Global Burden of Disease Study (GBD) 2021 datasets. The estimated prevalent food-borne trematodiase cases were 33.32 million (95% uncertainty interval (<i>UI</i>): 29.25-38.35 million) in China in 2021, contributing to 768,297.4 disability-adjusted life years (DALYs) (95% <i>UI</i>: 383,882.8-1,367,826.1). The number of prevalent cases and DALYs declined by 9.02% and 18.11%, and a downward decline was seen in age-standardized prevalence and DALY rates (estimated annual percentage change: -0.96% and -1.21%, respectively). A higher prevalence and DALY rates were observed among males than females, and the middle-aged group bore the highest burden, while the older population showed the most rapid increase in prevalent cases and DALY numbers. Projected DALY counts and rates remain stable through 2035 using the Bayesian age-period-cohort (BAPC) model. These findings demonstrate a decline in the burden of food-borne trematodiases in China from 1990 to 2021; however, the prevalence remained high, which contributed considerably to disability and premature death. Continued control efforts and targeted interventions are essential to further reducing the burden of food-borne trematodiases in China.</p>","PeriodicalId":23330,"journal":{"name":"Tropical Medicine and Infectious Disease","volume":"9 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}