发布求助
文献互助 智能选刊 最新文献

Trends in parasitology最新文献

筛选
英文 中文
Teratogenic parasites: disease mechanisms and emerging study models. 致畸寄生虫：疾病机制和新出现的研究模型。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-12-01 Epub Date: 2024-11-20 DOI: 10.1016/j.pt.2024.10.016
Rafaela Jose da Silva, Leah F Cabo, Jon P Boyle
{"title":"Teratogenic parasites: disease mechanisms and emerging study models.","authors":"Rafaela Jose da Silva, Leah F Cabo, Jon P Boyle","doi":"10.1016/j.pt.2024.10.016","DOIUrl":"10.1016/j.pt.2024.10.016","url":null,"abstract":"<p><p>Congenital infections are a leading preventable cause of pregnancy complications impacting both mother and fetus. Although advancements have been made in understanding various congenital infections, the mechanisms of parasitic infections during pregnancy remain poorly understood. This review covers the global incidence of three parasites capable of congenital transmission - Trypanosoma cruzi, Plasmodium spp., and Toxoplasma gondii - and the state of research into their transplacental transmission strategies. We highlight technological advancements in placental modeling that offer opportunities to reveal how parasites cause gestational pathology. Additionally, we discuss the likelihood that selective adaptation contributed to the evolution of mechanisms that facilitate placental infection. These insights provide a foundation for understanding the progression and pathology of congenital parasitic diseases and identifying future research directions.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"1159-1172"},"PeriodicalIF":7.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Young investigators in parasitology meeting: building foundations and supporting early-career researchers. 寄生虫学青年研究人员会议：奠定基础和支持早期职业研究人员。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-12-01 Epub Date: 2024-10-28 DOI: 10.1016/j.pt.2024.10.004
Filipa Rijo-Ferreira, Chi-Min Ho, Alex Rosenberg
{"title":"Young investigators in parasitology meeting: building foundations and supporting early-career researchers.","authors":"Filipa Rijo-Ferreira, Chi-Min Ho, Alex Rosenberg","doi":"10.1016/j.pt.2024.10.004","DOIUrl":"10.1016/j.pt.2024.10.004","url":null,"abstract":"","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"1063-1065"},"PeriodicalIF":7.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A hypothesis to explain malaria-induced neurocognitive sequelae. 一种解释疟疾引起的神经认知后遗症的假说。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-12-01 Epub Date: 2024-11-04 DOI: 10.1016/j.pt.2024.10.008
Yuri Chaves Martins, Cláudio Tadeu Daniel-Ribeiro
{"title":"A hypothesis to explain malaria-induced neurocognitive sequelae.","authors":"Yuri Chaves Martins, Cláudio Tadeu Daniel-Ribeiro","doi":"10.1016/j.pt.2024.10.008","DOIUrl":"10.1016/j.pt.2024.10.008","url":null,"abstract":"<p><p>The development of malaria-induced neurocognitive and behavioral sequelae is not entirely understood. We hypothesize that liver dysfunction caused by Plasmodium infection is responsible for malaria-induced neurocognitive and behavioral sequelae. Our metabolic hypothesis not only explains neurocognitive sequelae after cerebral malaria (CM) but also after other severe, non-severe, and asymptomatic malaria infections.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"1077-1080"},"PeriodicalIF":7.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CRISPR-based functional genomics for schistosomes and related flatworms. 基于 CRISPR 的血吸虫和相关扁形虫功能基因组学。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-18 DOI: 10.1016/j.pt.2024.09.010
Wannaporn Ittiprasert, Paul J Brindley
{"title":"CRISPR-based functional genomics for schistosomes and related flatworms.","authors":"Wannaporn Ittiprasert, Paul J Brindley","doi":"10.1016/j.pt.2024.09.010","DOIUrl":"10.1016/j.pt.2024.09.010","url":null,"abstract":"<p><p>CRISPR genome editing is actively used for schistosomes and other flukes. The ability to genetically manipulate these flatworms enables deeper investigation of their (patho)biological nature. CRISPR gene knockout (KO) demonstrated that a liver fluke growth mediator contributes to disease progression. Genome safe harbor sites have been predicted in Schistosoma mansoni and targeted for transgene insertion. CRISPR-based diagnosis has been demonstrated for infection with schistosomes and Opisthorchis viverrini. This review charts the progress, and the state of play, and posits salient questions for the field to address. Derivation of heritably transgenic loss-of-function or gain-of-function lines is the next milestone.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"1016-1028"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ties that bind us: Leishmania grasps the sandfly. 束缚我们的纽带利什曼病抓住了沙蝇。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-09-25 DOI: 10.1016/j.pt.2024.09.004
Scott M Landfear
{"title":"Ties that bind us: Leishmania grasps the sandfly.","authors":"Scott M Landfear","doi":"10.1016/j.pt.2024.09.004","DOIUrl":"10.1016/j.pt.2024.09.004","url":null,"abstract":"<p><p>The enigmatic haptomonad forms of Leishmania parasites adhere to the sandfly stomodeal valve, damaging this feeding valve and promoting parasite transmission. Yanase et al. recently identified the first parasite proteins involved in adhesion and showed their essentiality in binding to and damaging the valve.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"962-963"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reporter parasite lines: valuable tools for the study of Plasmodium biology. 报告寄生虫品系：研究疟原虫生物学的宝贵工具。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-09 DOI: 10.1016/j.pt.2024.09.003
Yukiko Miyazaki, Shinya Miyazaki
{"title":"Reporter parasite lines: valuable tools for the study of Plasmodium biology.","authors":"Yukiko Miyazaki, Shinya Miyazaki","doi":"10.1016/j.pt.2024.09.003","DOIUrl":"10.1016/j.pt.2024.09.003","url":null,"abstract":"<p><p>The human malaria parasite Plasmodium falciparum causes the most severe form of malaria in endemic regions and is transmitted via mosquito bites. To better understand the biology of this deadly pathogen, a variety of P. falciparum reporter lines have been generated using transgenic approaches to express reporter proteins, such as fluorescent proteins and luciferases. This review discusses the advances in recently generated P. falciparum transgenic reporter lines, which will aid in the investigation of parasite physiology and the discovery of novel antimalarial drugs. Future prospects for the generation of new and superior human malaria parasite reporter lines are also discussed, and unresolved questions in malaria biology are highlighted to help boost support for the development and implementation of malaria treatments.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"1000-1015"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunological clues to sex differences in parasitic diseases. 寄生虫病性别差异的免疫学线索。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-07 DOI: 10.1016/j.pt.2024.09.006
Julie Sellau, Charlotte Sophie Hansen, Rosa Isela Gálvez, Lara Linnemann, Barbara Honecker, Hanna Lotter
{"title":"Immunological clues to sex differences in parasitic diseases.","authors":"Julie Sellau, Charlotte Sophie Hansen, Rosa Isela Gálvez, Lara Linnemann, Barbara Honecker, Hanna Lotter","doi":"10.1016/j.pt.2024.09.006","DOIUrl":"10.1016/j.pt.2024.09.006","url":null,"abstract":"<p><p>The effect of sex on the prevalence and severity of parasitic diseases is an emerging area of research. Several factors underlie sex-based differences, including sociocultural influences that affect exposure to parasites, and physiological disparities linked to biological sex. Hence, human studies must be interpreted cautiously; however, studies conducted under controlled laboratory conditions are important to validate findings in humans. Such research can more effectively elucidate the role of sex-determining physiological factors (particularly their impact on immune responses), as well as the role of sex-specific differences in resistance to, or severity of, parasitic diseases. This review focuses on the overarching impact of biological sex variables on immunity. Both human and rodent experimental data are discussed, with a focus on selected protozoan and helminth infections.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"1029-1041"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ICAP 2024: anaerobic protozoology in focus, a partnership with parasitology societies in the South Pacific. ICAP 2024：厌氧原生动物学聚焦，与南太平洋寄生虫学会合作。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-14 DOI: 10.1016/j.pt.2024.09.011
Augusto Simoes-Barbosa, Kathryn M McRae, Tania S Waghorn, Pavel Dolezal, Katherine S Ralston, Ivana Bilic, Robert P Hirt, Steven A Sullivan, Tomoyoshi Nozaki
{"title":"ICAP 2024: anaerobic protozoology in focus, a partnership with parasitology societies in the South Pacific.","authors":"Augusto Simoes-Barbosa, Kathryn M McRae, Tania S Waghorn, Pavel Dolezal, Katherine S Ralston, Ivana Bilic, Robert P Hirt, Steven A Sullivan, Tomoyoshi Nozaki","doi":"10.1016/j.pt.2024.09.011","DOIUrl":"10.1016/j.pt.2024.09.011","url":null,"abstract":"","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"935-941"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Turning up the heat: infrared sensing during mosquito host-seeking. 升温：蚊子寻找宿主时的红外感应。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-17 DOI: 10.1016/j.pt.2024.10.002
Auguste de Pennart, Pei-Hsuan Wu, Benjamin J Matthews
{"title":"Turning up the heat: infrared sensing during mosquito host-seeking.","authors":"Auguste de Pennart, Pei-Hsuan Wu, Benjamin J Matthews","doi":"10.1016/j.pt.2024.10.002","DOIUrl":"10.1016/j.pt.2024.10.002","url":null,"abstract":"<p><p>The yellow fever mosquito Aedes aegypti uses multiple sensory systems to identify a blood-meal victim. Recent work by Chandel et al. identifies infrared radiation as a medium-distance cue acting through TrpA1 and two opsins to help target hosts, furthering our understanding of the multisensory hunting strategy used by mosquitoes on the prowl.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"954-955"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microhaplotypes: the QR-code for Plasmodium vivax infection dynamics. 微组型：间日疟原虫感染动态的 QR 代码。
IF 7 1区 医学
Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-19 DOI: 10.1016/j.pt.2024.10.005
Manoswini Dash, Prashant Kumar Mallick
{"title":"Microhaplotypes: the QR-code for Plasmodium vivax infection dynamics.","authors":"Manoswini Dash, Prashant Kumar Mallick","doi":"10.1016/j.pt.2024.10.005","DOIUrl":"10.1016/j.pt.2024.10.005","url":null,"abstract":"<p><p>An array of microhaplotypes - small segments of ≤200 nucleotides with heterozygous multiple-SNP exhibiting multiple allelic combinations - were identified in the Plasmodium vivax genome by Siegel et al. Interestingly, the microhaplotype has significant potential to distinguish relapse/reinfection and identify genetic relatedness across vivax-endemic areas. It is essential to validate the universal applicability of microhaplotypes.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"959-961"},"PeriodicalIF":7.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信