Vidarbha Journal of Internal Medicine最新文献_第2页

Newer FDCs in Indian Market are they Rational or Irrational 印度市场上较新的fdc是理性的还是非理性的

Vidarbha Journal of Internal Medicine Pub Date : 2023-04-06 DOI: 10.25259/vjim_1_2023

Sandeep V. Kharkar

引用次数: 0

Insulin Resistance 胰岛素抵抗

Vidarbha Journal of Internal Medicine Pub Date : 2023-04-06 DOI: 10.25259/vjim_41_2022

Sunanda Ashutosh Chaoji

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Disseminated Tuberculosis with Poncet’s Disease Masquerading as Systemic Lupus Erythematosus – A Case Report 以系统性红斑狼疮为伪装的播散性肺结核伴蓬塞病1例报告

Vidarbha Journal of Internal Medicine Pub Date : 2023-04-06 DOI: 10.25259/vjim_39_2022

A. R., Gyanshankar P. Mishra, R. Munje, Sanjay Gour

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Management of Paroxysmal Supraventricular Tachycardia with Electrophysiology Study and Radiofrequency Ablation 电生理学研究和射频消融治疗阵发性室上性心动过速

Vidarbha Journal of Internal Medicine Pub Date : 2023-04-06 DOI: 10.25259/vjim_26_2022

Manisha K. Juneja, Pankaj Raut, M. Lohkare, Harshawardhan Dhanraj Ramteke, Vaishnavi Jayant Walke, Sakshi Bhatia

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D-dimer Levels to Predict in-Hospital Mortality in ICU Patients with COVID-19 d -二聚体水平预测COVID-19 ICU患者住院死亡率

Vidarbha Journal of Internal Medicine Pub Date : 2023-04-06 DOI: 10.5005/jp-journals-10071-23712A.131

R. Hasani, Mohan N. Nerkar, P. Rahate, Venus Sadhwani

{"title":"D-dimer Levels to Predict in-Hospital Mortality in ICU Patients with COVID-19","authors":"R. Hasani, Mohan N. Nerkar, P. Rahate, Venus Sadhwani","doi":"10.5005/jp-journals-10071-23712A.131","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-23712A.131","url":null,"abstract":"\u0000\u0000Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing various intensive care unit (ICU) admissions and deaths. Common laboratory values may provide key insights into patients with COVID-19, and may predict the morbidity and outcome. The aim of this study was to evaluate the relation of elevated D-dimer levels on mortality of patients admitted to ICU with COVID-19.\u0000\u0000\u0000\u0000All ICU patients with laboratory confirmed COVID-19 were retrospectively enrolled in Sevenstar Hospital, Nagpur from 27 July, 2020, to 30 October, 2020. D-dimer levels on admission, on Day 3 and Day 5, were collected in all ICU patients and death events were collected. The subjects were divided into two groups discharged and expired. Then, the D-dimer levels between two groups were compared to assess the predictive value of D-dimer level and mortality in hospitals.\u0000\u0000\u0000\u0000A total of 101 eligible patients were enrolled in the study. Thirty-one deaths occurred during hospitalisation. Patients who expired had on admission D-dimer levels of 2729 ± 3243 ng/mL while those discharged had D-dimer values of 973 ± 1553 ng/mL (P < 0.007). D-dimer of expired patients on Day 3 was 3206.5 ± 3338.8 and of discharged patients was 828.8 ± 1268.8 (P = 0.001). D-dimer of expired patients on Day 5 was 5184. 5 ± 3386.1 versus discharged patients was 588.7 ± 645.5 (P < 0.0001). Number of Days in ICU for patients who expired was 14.22 ± 6.7 while for those who survived 7.6 ± 5.9.\u0000\u0000\u0000\u0000We conclude that SARS-CoV-2 infected patients with increasing trend of D-dimer (from admission to day 5) have worse clinical outcomes (all-cause mortality), and thus, measurement of D-dimers on admission and its trend can guide clinical decision-making.\u0000","PeriodicalId":232453,"journal":{"name":"Vidarbha Journal of Internal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127643973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Polysomnography in Patients of Metabolic Syndrome 代谢综合征患者多导睡眠图的研究

Vidarbha Journal of Internal Medicine Pub Date : 2022-08-10 DOI: 10.25259/vjim_11_2022

R. Munje, Amol Laxman Ramteke, Gyanshankar P. Mishra

{"title":"Study of Polysomnography in Patients of Metabolic Syndrome","authors":"R. Munje, Amol Laxman Ramteke, Gyanshankar P. Mishra","doi":"10.25259/vjim_11_2022","DOIUrl":"https://doi.org/10.25259/vjim_11_2022","url":null,"abstract":"\u0000\u0000Obstructive sleep apnoea (OSA) is a condition wherein collapse of the upper airway during sleep results in decreased or complete cessation of airflow. The association of OSA with increased cardiovascular morbidity, mortality, and various cardiovascular risk factors is known for a long time. Metabolic syndrome a cluster of metabolic abnormalities, with insulin resistance as the central pathophysiological feature is ‘Syndrome X’ and in association with OSA is ‘Syndrome Z’. The aims of this study were as follows: (1) To study the incidence of OSA in patients with metabolic syndrome, (2) to study and correlate the severity of OSA with metabolic syndrome.\u0000\u0000\u0000\u0000This is a hospital-based observational study conducted in Department of Respiratory Medicine IGGMC, Nagpur.\u0000\u0000\u0000\u0000In the present study of ‘polysomnography in patients of metabolic syndrome’; 50 cases of metabolic syndrome were evaluated. 20 (55.55%) subjects were in the age group of 40–50 years. 22 (44%) subjects had moderate excessive daytime sleepiness, followed by higher normal daytime sleepiness in 14 (28%) based on Epworth sleepiness scale. Of the 50 subjects of Metabolic Syndrome, 14 (28%) had Apnoea Hypopnea Index (AHI) <5 and 36 (72%) had AHI 5 or more, of which 42% had mild sleep apnoea, 22% moderate sleep apnoea and 8% severe sleep apnoea.\u0000\u0000\u0000\u0000Prevalence of Syndrome Z was found to be high in patients of metabolic syndrome .\u0000","PeriodicalId":232453,"journal":{"name":"Vidarbha Journal of Internal Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115204192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Wrapped up in Rarity: A Case of Multiple Autoimmune Syndrome 罕见:一例多重自身免疫综合征

Vidarbha Journal of Internal Medicine Pub Date : 2022-08-10 DOI: 10.25259/vjim_13_2022

Sharang Gupta, D. Chopra

引用次数: 1

A Case of Intracranial Aneurysm Masquerading as Space-Occupying Lesion 颅内动脉瘤伪装成占位性病变1例

Vidarbha Journal of Internal Medicine Pub Date : 2022-08-10 DOI: 10.25259/vjim_5_2022

Vinod Khandait, Nandita Bagchi

引用次数: 0

Clinical Profile of Diabetic Nephropathy and its Correlation with Neutrophil-Lymphocyte Ratio in Type 2 Diabetes Mellitus 2型糖尿病肾病的临床特征及其与中性粒细胞-淋巴细胞比值的关系

Vidarbha Journal of Internal Medicine Pub Date : 2022-08-10 DOI: 10.25259/vjim_18_2022

M. E. Murughesh, M. Holay, Prashant Patil, P. Tayade

{"title":"Clinical Profile of Diabetic Nephropathy and its Correlation with Neutrophil-Lymphocyte Ratio in Type 2 Diabetes Mellitus","authors":"M. E. Murughesh, M. Holay, Prashant Patil, P. Tayade","doi":"10.25259/vjim_18_2022","DOIUrl":"https://doi.org/10.25259/vjim_18_2022","url":null,"abstract":"\u0000\u0000Diabetic nephropathy (DN) is a microvascular complication of diabetes. It manifests clinically as albuminuria which is the precursor of end-stage renal failure. This is considered to be an inflammatory process. In recent past, it has been reported that the neutrophil-lymphocyte ratio (NLR) may be a favourable indicator of the inflammatory status. It is cost effective and easily accessible marker. The present research was undertaken to study the clinical profile of DN and to see the association between NLR and DN in patients with type 2 diabetes mellitus (DM).\u0000\u0000\u0000\u0000A total of 210 patients were enrolled, of them 105 healthy individuals without diabetes were taken as controls and cases were 105 subjects with type 2 diabetes. Patients were, further, divided based on urine albumin creatinine ratio (UACR) into DM without nephropathy (UACR <30 mg/g) group and DM with nephropathy (UACR >30 mg/g) group. For intragroup comparison, DM with nephropathy group was, further, divided into microalbuminuria (UACR 30–300 mg/g) and macroalbuminuria (UACR >300 mg/g).\u0000\u0000\u0000\u0000NLR was found significantly increased (P < 0.0001) in patients with DN (2.81 ± 0.51) as compared with DM without nephropathy (2.12 ± 0.64) and healthy adults (2.06 ± 0.29). However, NLR value was unable to differentiate between patients with microalbuminuria and macroalbuminuria. There was a significant correlation between NLR and DN in type 2 diabetes while there was no statistically significant difference in distribution of NLR in different stages of chronic kidney disease.\u0000\u0000\u0000\u0000NLR can be used as a novel biomarker of DN in patients with type 2 DM.\u0000","PeriodicalId":232453,"journal":{"name":"Vidarbha Journal of Internal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130462812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delirium: Fallout of Neuro-Behcet’s Disease – A Case Report 谵妄:神经性白塞病的影响-一例报告

Vidarbha Journal of Internal Medicine Pub Date : 2022-08-10 DOI: 10.25259/vjim_12_2022

Shahnawaz Ahmed Siddiqui, Aamol Meshram, Imran Noormohammed, Vikas Gupta

{"title":"Delirium: Fallout of Neuro-Behcet’s Disease – A Case Report","authors":"Shahnawaz Ahmed Siddiqui, Aamol Meshram, Imran Noormohammed, Vikas Gupta","doi":"10.25259/vjim_12_2022","DOIUrl":"https://doi.org/10.25259/vjim_12_2022","url":null,"abstract":"Here, we present a case of an elderly male with hypertension and diabetes, who presented to ER with delirium, ataxia, and slurring of speech associated with altered psychomotor behaviour, also features such as anorexia, painful erythematous patches over extremities, tender knee, and ankle joints were conspicuous at presentation. A brain scan on admission revealed multiple lacunar cerebellar infarcts, whereas routine blood investigations did not reveal anything substantial contributions to the cause of presenting symptoms, including negative serology for ANA, DS-DNA, HAL-B51, and anticardiolipin antibodies, done to rule in, presence of systemic autoimmune causes for the gamut of clinical features at presentation. Contemplation over past and associated clinical features, such as ocular ailment, recurrent aphthous ulcers, dermatological lesions (erythema nodosum and peudofolliculitis), and past MRI showing lesions in the thalamus and pons (diencephalon predilection) a diagnosis of Behcet’s disease (BD) was considered based on ‘International Study Group Diagnostic Criteria for BD’. More so in the event of no better explanation for the neurological involvement, in a diagnosed case of BD, presenting delirium was considered to be the fallout of Neuro-Behcet’s Disease (NBD). The Patient responded to steroids and was discharged on a combination of tapering doses of steroids with Azathioprine. Emphasising the fact that the central nervous system affection in a case presenting with signs of systemic inflammation, autoimmune vasculitis as a cause of neurological involvement should be considered, as this is critical for deciding onto the course of treatment. NBD being secondary to systemic vasculitis as compared to atherosclerotic vascular affection seen in regular stroke, require steroids and immunomodulators rather than antiplatelets and anticoagulants.","PeriodicalId":232453,"journal":{"name":"Vidarbha Journal of Internal Medicine","volume":"15 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113975197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0