Study of Polysomnography in Patients of Metabolic Syndrome

Abstract

Obstructive sleep apnoea (OSA) is a condition wherein collapse of the upper airway during sleep results in decreased or complete cessation of airflow. The association of OSA with increased cardiovascular morbidity, mortality, and various cardiovascular risk factors is known for a long time. Metabolic syndrome a cluster of metabolic abnormalities, with insulin resistance as the central pathophysiological feature is ‘Syndrome X’ and in association with OSA is ‘Syndrome Z’. The aims of this study were as follows: (1) To study the incidence of OSA in patients with metabolic syndrome, (2) to study and correlate the severity of OSA with metabolic syndrome. This is a hospital-based observational study conducted in Department of Respiratory Medicine IGGMC, Nagpur. In the present study of ‘polysomnography in patients of metabolic syndrome’; 50 cases of metabolic syndrome were evaluated. 20 (55.55%) subjects were in the age group of 40–50 years. 22 (44%) subjects had moderate excessive daytime sleepiness, followed by higher normal daytime sleepiness in 14 (28%) based on Epworth sleepiness scale. Of the 50 subjects of Metabolic Syndrome, 14 (28%) had Apnoea Hypopnea Index (AHI) <5 and 36 (72%) had AHI 5 or more, of which 42% had mild sleep apnoea, 22% moderate sleep apnoea and 8% severe sleep apnoea. Prevalence of Syndrome Z was found to be high in patients of metabolic syndrome .