Tobacco Induced Diseases最新文献

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Tobacco exposure and alcohol drinking prevalence and associations with hypertension in rural southwest China: A cross-sectional study. 中国西南农村地区烟草暴露和饮酒流行率及其与高血压的关系:一项横断面研究。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-10 eCollection Date: 2024-01-01 DOI: 10.18332/tid/189222
Guohui Li, Lan Liu, Du-Li Liu, Zi-Zi Yu, Allison R Golden, Xiang-Yang Yin, Le Cai
{"title":"Tobacco exposure and alcohol drinking prevalence and associations with hypertension in rural southwest China: A cross-sectional study.","authors":"Guohui Li, Lan Liu, Du-Li Liu, Zi-Zi Yu, Allison R Golden, Xiang-Yang Yin, Le Cai","doi":"10.18332/tid/189222","DOIUrl":"10.18332/tid/189222","url":null,"abstract":"<p><strong>Introduction: </strong>This study examined the prevalence of tobacco exposure and drinking and ascertained the relationships between tobacco exposure, alcohol drinking, concurrent smoking and drinking, and hypertension in rural southwestern China.</p><p><strong>Methods: </strong>Data were collected from a cross-sectional health interview and examination survey, which included 7572 adults aged ≥35 years, in rural China. Participant demographic characteristics, smoking habits, exposure to secondhand smoke (SHS), and alcohol drinking habits were obtained using a standard questionnaire. Blood pressure (BP), height, weight, and waist circumference were measured for each participant.</p><p><strong>Results: </strong>The overall prevalence of smoking, SHS exposure, drinking, concurrent smoking and drinking, concurrent exposure to SHS and drinking, and hypertension was 37.7%, 27.4%, 16.2%, 12.6%, 1.6%, and 41.3%, respectively. Males had a significantly higher prevalence of smoking (74.1% vs 2.2%, p<0.01), drinking (31.1% vs 1.7%, p<0.01), and concurrent smoking and drinking than females (25.3% vs 0.3%, p<0.01). However, females had a higher prevalence of SHS exposure than males (30.2% vs 20.6%, p<0.01). Ethnic minorities had a higher prevalence of SHS exposure, drinking, and concurrent smoking and drinking, than Han participants (p<0.01). Participants with a higher education level had a higher prevalence of smoking, drinking, and concurrent smoking and drinking than their counterparts (p<0.01). In contrast, participants with a lower education level had a higher prevalence of SHS exposure than their counterparts (p<0.01). Multivariate logistic regression analysis found that smokers (AOR=1.31; 95% CI: 1.13-1.51), individuals exposed to SHS (AOR=1.24; 95% CI: 1.11-1.43), drinkers (AOR=1.31; 95%: CI: 1.15-1.50), and concurrent smokers and drinkers (AOR=1.45; 95% CI: 1.25-1.67) all had a higher probability of having hypertension (p<0.01). Additionally, concurrent smoking and drinking had the strongest association with the prevalence of hypertension (AOR=1.45; 95% CI: 1.25-1.67; p<0.01).</p><p><strong>Conclusions: </strong>Socioeconomic factors play an important role in influencing the prevalence of smoking, exposure to SHS, and drinking in rural southwest China. Interventions to prevent and reduce hypertension should, in particular, focus on smokers, individuals exposed to SHS, drinkers, and, in particular, concurrent smokers and drinkers.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the mediation effects of cigarettes per day on time to first cigarette and carcinogen biomarkers: National Health and Nutrition Examination Survey 2015-2016. 了解每日吸烟量对首次吸烟时间和致癌物生物标志物的中介效应:2015-2016年全国健康与营养调查。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-10 eCollection Date: 2024-01-01 DOI: 10.18332/tid/187766
Wenxue Lin
{"title":"Understanding the mediation effects of cigarettes per day on time to first cigarette and carcinogen biomarkers: National Health and Nutrition Examination Survey 2015-2016.","authors":"Wenxue Lin","doi":"10.18332/tid/187766","DOIUrl":"10.18332/tid/187766","url":null,"abstract":"<p><strong>Introduction: </strong>Previous research indicates that cigarette smokers with a time to first cigarette (TTFC) of less than 30 minutes after waking up had significantly higher levels of carcinogen biomarkers compared to those with a TTFC of more than 30 minutes. The mediation (potential mediator: cigarettes smoked per day) between TTFC and carcinogen biomarkers, remains unclear and has yet to be established.</p><p><strong>Methods: </strong>Multivariable linear regression models were used to estimate adjusted geometric means (GMs) and ratios of GMs for urine biomarkers of VOCs by smokers' TTFC status (≤30 vs >30 min). Further, data from the NHANES 2015-2016 special sample were analyzed to assess the mediation between TTFC (exposure) and carcinogen biomarkers, including urine metabolites of polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds (VOCs), and cadmium.</p><p><strong>Results: </strong>Cigarette smokers with a short TTFC (≤30 min) presented significantly higher concentrations in 8 out of 17 urine metabolites of VOCs examined compared to smokers with TTFC >30 min. The association between exposure and carcinogen biomarkers was not mediated by CPD.</p><p><strong>Conclusions: </strong>Cigarette smokers with a short TTFC (≤30 min) had significantly higher levels in VOCs, PAHs, and cadmium, but the association was not mediated by cigarettes smoked per day.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges in current inhalable tobacco toxicity assessment models: A narrative review. 当前可吸入烟草毒性评估模型面临的挑战:叙述性综述。
IF 2.2 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-10 eCollection Date: 2024-01-01 DOI: 10.18332/tid/188197
Thivanka Muthumalage, Alexandra Noel, Yasmin Thanavala, Aleksandra Alcheva, Irfan Rahman
{"title":"Challenges in current inhalable tobacco toxicity assessment models: A narrative review.","authors":"Thivanka Muthumalage, Alexandra Noel, Yasmin Thanavala, Aleksandra Alcheva, Irfan Rahman","doi":"10.18332/tid/188197","DOIUrl":"10.18332/tid/188197","url":null,"abstract":"<p><p>Emerging tobacco products such as electronic nicotine delivery systems (ENDS) and heated tobacco products (HTPs) have a dynamic landscape and are becoming widely popular as they claim to offer a low-risk alternative to conventional smoking. Most pre-clinical laboratories currently exploit <i>in vitro</i>, <i>ex vivo</i>, and <i>in vivo</i> experimental models to assess toxicological outcomes as well as to develop risk-estimation models. While most laboratories have produced a wide range of cell culture and mouse model data utilizing current smoke/aerosol generators and standardized puffing profiles, much variation still exists between research studies, hindering the generation of usable data appropriate for the standardization of these tobacco products. In this review, we discuss current state-of-the-art <i>in vitro</i> and <i>in vivo</i> models and their challenges, as well as insights into risk estimation of novel products and recommendations for toxicological parameters for reporting, allowing comparability of the research studies between laboratories, resulting in usable data for regulation of these products before approval by regulatory authorities.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The inclusion of e-cigarettes and heated tobacco products in smoke-free home and car rules: A cross-sectional survey of adults in Armenia and Georgia. 将电子烟和加热烟草制品纳入家庭和汽车无烟规定:对亚美尼亚和格鲁吉亚成年人的横断面调查。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-04 eCollection Date: 2024-01-01 DOI: 10.18332/tid/189200
Varduhi Hayrumyan, Zhanna Sargsyan, Arevik Torosyan, Ana Dekanosidze, Lilit Grigoryan, Nour Alayan, Michelle C Kegler, Lela Sturua, Varduhi Petrosyan, Alexander Bazarchyan, Regine Haardörfer, Yuxian Cui, Carla J Berg
{"title":"The inclusion of e-cigarettes and heated tobacco products in smoke-free home and car rules: A cross-sectional survey of adults in Armenia and Georgia.","authors":"Varduhi Hayrumyan, Zhanna Sargsyan, Arevik Torosyan, Ana Dekanosidze, Lilit Grigoryan, Nour Alayan, Michelle C Kegler, Lela Sturua, Varduhi Petrosyan, Alexander Bazarchyan, Regine Haardörfer, Yuxian Cui, Carla J Berg","doi":"10.18332/tid/189200","DOIUrl":"10.18332/tid/189200","url":null,"abstract":"<p><strong>Introduction: </strong>Understanding who includes e-cigarettes and heated tobacco products (HTPs) in smoke-free home or car rules could inform public health interventions, particularly in countries with high smoking prevalence and recently implemented national smoke-free laws, like Armenia and Georgia.</p><p><strong>Methods: </strong>In 2022, we conducted a cross-sectional survey among 1468 adults in 28 Armenian and Georgian communities (mean age=42.92 years; 51.4% female, 31.6% past-month smoking). Multilevel regression (accounting for clustering within communities; adjusted for sociodemographics and cigarette use) examined e-cigarette/HTP perceptions (risk, social acceptability) and use intentions in relation to: 1) including e-cigarettes/HTPs in home and car rules among participants with home and car rules, respectively (logistic regressions); and 2) intention to include e-cigarettes/HTPs in home rules (linear regression, 1 = 'not at all' to 7 = 'extremely') among those without home rules.</p><p><strong>Results: </strong>Overall, 72.9% (n=1070) had home rules, 86.5% of whom included e-cigarettes/HTPs; 33.9% (n=498) had car rules, 81.3% of whom included e-cigarettes/HTPs. Greater perceived e-cigarette/HTP risk was associated with including e-cigarettes/HTPs in home rules (AOR=1.28; 95% CI: 1.08-1.50) and car rules (AOR=1.46; 95% CI: 1.14-1.87) and next-year intentions to include e-cigarettes/HTPs in home rules (β=0.38; 95% CI: 0.25-0.50). Lower e-cigarette/HTP use intentions were associated with including e-cigarettes/HTPs in home rules (AOR=0.75; 95% CI: 0.63-0.88). While perceived social acceptability was unassociated with the outcomes, other social influences were: having children and no other household smokers was associated with including e-cigarettes/HTPs in car rules, and having children was associated with intent to include e-cigarettes/HTPs in home rules.</p><p><strong>Conclusions: </strong>Interventions to address gaps in home and car rules might target e-cigarette/HTP risk perceptions.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of smoking on prostate cancer: Results from the National Health and Nutrition Examination Survey 2003-2018 and Mendelian randomization analyses. 吸烟对前列腺癌的影响:2003-2018年全国健康与营养调查的结果以及孟德尔随机分析。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-04 eCollection Date: 2024-01-01 DOI: 10.18332/tid/189199
Hairong He, Liang Liang, Tao Tian, Xiaoyu Zhang, Jun Lyu
{"title":"Effect of smoking on prostate cancer: Results from the National Health and Nutrition Examination Survey 2003-2018 and Mendelian randomization analyses.","authors":"Hairong He, Liang Liang, Tao Tian, Xiaoyu Zhang, Jun Lyu","doi":"10.18332/tid/189199","DOIUrl":"10.18332/tid/189199","url":null,"abstract":"<p><strong>Introduction: </strong>The controversial relationship between smoking and prostate cancer (PCa) risk prompted us to conduct a cross-sectional study using the National Health and Nutrition Examination Survey (NHANES) database and apply Mendelian randomization (MR) analyses in order to clarify the possible causal effect of smoking on PCa risk.</p><p><strong>Methods: </strong>Using univariate and multivariate logistic regression methods, a secondary analysis of the pooled 2003-2018 NHANES dataset was performed to explore the association between smoking and PCa risk. Propensity-score matching was used to reduce selection bias. Then, we conducted subsequent MR analysis study to investigate the potential causal effect of smoking on PCa risk, with genetic variants of four exposure factors including the lifetime smoking index, light smoking, smoking initiation, and the amount of smoking per day obtained from genome-wide association studies, and PCa summary statistics obtained from three database populations. Inverse-variance weighting was the primary analytical method, and weighted median and MR-Egger regression were used for sensitivity analyses. The MR results for the three PCa databases were combined using meta-analysis.</p><p><strong>Results: </strong>The study included 16073 NHANES subjects, comprising 554 with PCa and 15519 without PCa. Logistic regression before and after matching did not reveal any significant association. Meta-analysis of the MR results also did not support an association of PCa risk with lifetime smoking index (OR=0.95; 95% CI: 0.83-1.09), light smoking (OR=1.00; 95% CI: 0.95-1.06), smoking initiation (OR=0.99, 95% CI=0.99-1.00), or the amount of smoking per day (OR=1.00; 95% CI: 0.99-1.00) and PCa risk.</p><p><strong>Conclusions: </strong>There was no evidence for an association between smoking and the risk of PCa. Further studies are needed to determine if there are any associations of other forms of smoking with the risk of PCa at different stages.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141246699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns and determinants of tobacco purchase behaviors among male cigarette smokers in Vietnam: A latent class analysis. 越南男性吸烟者购买烟草行为的模式和决定因素:潜类分析
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-04 eCollection Date: 2024-01-01 DOI: 10.18332/tid/187869
Thi Ngoc Phuong Nguyen, Monica Hunsberger, Jesper Löve, Tu Anh Duong, Thi Hai Phan, Ngoc Khue Luong, Van Minh Hoang, Nawi Ng
{"title":"Patterns and determinants of tobacco purchase behaviors among male cigarette smokers in Vietnam: A latent class analysis.","authors":"Thi Ngoc Phuong Nguyen, Monica Hunsberger, Jesper Löve, Tu Anh Duong, Thi Hai Phan, Ngoc Khue Luong, Van Minh Hoang, Nawi Ng","doi":"10.18332/tid/187869","DOIUrl":"10.18332/tid/187869","url":null,"abstract":"<p><strong>Introduction: </strong>Understanding smokers' purchasing patterns can aid in customizing tobacco control initiatives aimed at reducing the tobacco smoking prevalence. Therefore, this study identified cigarette purchase behavior among Vietnamese male smokers and associated demographic and consumption factors.</p><p><strong>Methods: </strong>We analyzed a secondary dataset of male current tobacco smokers (n=3983) who participated in the Vietnam Global Adult Tobacco Survey in 2015. We applied the latent class analysis (LCA) to identify the classes of purchase behavior among cigarette smokers (n=1241). Multinomial logistic regression was performed to identify demographics (education level, ethnicity, partnership status, and household socioeconomic status) and cigarette consumption variables (smoking years and heavy smoking status) related to purchase behavior classes. The results are reported as an adjusted relative risk ratio (ARRR).</p><p><strong>Results: </strong>The LCA identified four cigarette purchase behaviors classes: Class 1 (price-insensitive and purchased international brand: 44.4%), Class 2 (price-sensitive and purchased domestic brand: 27.6%), Class 3 (price-sensitive and purchased cigarettes in a street vendor: 18.6%), and Class 4: price-sensitive and purchased loose/carton cigarette: 9.4%). The poorer economic groups were more likely to belong to the three price-sensitive classes. Heavy smokers and those who had smoked for a longer period were more likely to belong to Class 3 (ARRR=2.33; 95% CI: 1.51-3.58 and ARRR=1.02; 95% CI: 1.001-1.05, respectively) and Class 4 (ARRR=2.94; 95% CI: 1.71-5.06 and ARRR=1.05; 95% CI: 1.02-1.08, respectively).</p><p><strong>Conclusions: </strong>Varied purchasing behaviors among male cigarette smokers, influenced by divergent price sensitivities and economic backgrounds, underscore the need for comprehensive tobacco control. Future efforts should include targeted policy interventions, behavior modification, and reshaping social norms.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the direct economic impact of smoking-related hospitalizations in Italy. 意大利吸烟相关住院的直接经济影响分析。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-03 eCollection Date: 2024-01-01 DOI: 10.18332/tid/188111
Irene Possenti, Marco Scala, Magda Rognoni, Alessandra Lugo, Maria S Cattaruzza, Sabrina Molinaro, Anna Odone, Luc J M Smits, Vincenzo Zagà, Silvano Gallus, Luca Cavalieri d'Oro
{"title":"Analysis of the direct economic impact of smoking-related hospitalizations in Italy.","authors":"Irene Possenti, Marco Scala, Magda Rognoni, Alessandra Lugo, Maria S Cattaruzza, Sabrina Molinaro, Anna Odone, Luc J M Smits, Vincenzo Zagà, Silvano Gallus, Luca Cavalieri d'Oro","doi":"10.18332/tid/188111","DOIUrl":"10.18332/tid/188111","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco-related diseases have a substantial economic impact in terms of medical expenses, loss of productivity, and premature death. Tobacco use is estimated to be responsible for more than 90000 deaths each year in Italy. We aimed to evaluate the annual direct economic impact on the National Health System of hospitalizations attributable to tobacco smoking in Italy.</p><p><strong>Methods: </strong>We analyzed data from all the hospitalizations of patients aged ≥30 years that occurred in Italy for 12 selected tobacco-related diseases, during 2018. These diseases included oropharyngeal cancer, esophageal cancer, gastric cancer, lung cancer, pancreatic cancer, bladder cancer, laryngeal cancer, ischemic heart disease, stroke, diseases of arteries, arterioles, and capillaries, pneumonia and influenza, and chronic obstructive pulmonary disease. We obtained information on 984322 hospital discharge records, including each hospitalization's direct costs. Using relative risk estimates from the scientific literature, we computed the population attributable fraction for various tobacco-related diseases to estimate the economic impact attributable to tobacco smoking.</p><p><strong>Results: </strong>One-third of all hospitalizations occurred in 2018 in Italy among people aged ≥30 years for 12 tobacco-related diseases were found to be attributable to smoking, accounting for a total cost of €1.64 billion. Among the diseases considered, those with the highest expenditures attributable to tobacco smoking were ischemic heart disease, cerebrovascular disease, and lung cancer, accounting for €556 million, €290 million, and €229 million, respectively.</p><p><strong>Conclusions: </strong>Tobacco has a substantial economic impact in Italy, accounting for around 6% of the total cost of hospitalizations in 2018. This figure is expected to be largely underestimated due to several conservative assumptions adopted in the statistical analyses. It is imperative to prioritize comprehensive tobacco control measures to counteract the huge healthcare costs due to tobacco smoking.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11145629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A scoping review of the toxicity and health impact of IQOS. 对 IQOS 的毒性和健康影响进行范围审查。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-06-03 eCollection Date: 2024-01-01 DOI: 10.18332/tid/188867
Sarah Ghazi, Min-Ae Song, Ahmad El-Hellani
{"title":"A scoping review of the toxicity and health impact of IQOS.","authors":"Sarah Ghazi, Min-Ae Song, Ahmad El-Hellani","doi":"10.18332/tid/188867","DOIUrl":"10.18332/tid/188867","url":null,"abstract":"<p><p>This work aims to summarize the current evidence on the toxicity and health impact of IQOS, taking into consideration the data source. On 1 June 2022, we searched PubMed, Web of Science, and Scopus databases using the terms: 'heated tobacco product', 'heat-not-burn', 'IQOS', and 'tobacco heating system'. The search was time-restricted to update a previous search conducted on 8 November 2021, on IQOS data from 2010-2021. The data source [independent, Philip Morris International (PMI), or other manufacturers] was retrieved from relevant sections of each publication. Publications were categorized into two general categories: 1) Toxicity assessments included in vitro, in vivo, and systems toxicology studies; and 2) The impact on human health included clinical studies assessing biomarkers of exposure and biomarkers of health effects. Generally, independent studies used classical in vitro and in vivo approaches, but PMI studies combined these with modeling of gene expression (i.e. systems toxicology). Toxicity assessment and health impact studies covered pulmonary, cardiovascular, and other systemic toxicity. PMI studies overall showed reduced toxicity and health risks of IQOS compared to cigarettes, but independent data did not always conform with this conclusion. This review highlights some discrepancies in IQOS risk assessment regarding methods, depth, and breadth of data collection, as well as conclusions based on the data source.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11145630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
E-cigarette use among Ecuadorian adults: A national cross-sectional study on use rates, perceptions, and associated factors. 厄瓜多尔成年人使用电子烟的情况:关于使用率、认知和相关因素的全国横断面研究。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.18332/tid/187878
Juan S Izquierdo-Condoy, Patricio Naranjo-Lara, Estefanía Morales-Lapo, Alexander Puglla-Mendoza, Marlon R Hidalgo, Andrea Tello-De-la-Torre, Eduardo Vásconez-González, Nathaly Izquierdo-Condoy, David Sánchez-Ordoñez, Galo S Guerrero-Castillo, Raúl F De la Rosa, Paul Vinueza-Moreano, Romina Placencia-André, M Fernanda Díaz, Esteban Ortiz-Prado
{"title":"E-cigarette use among Ecuadorian adults: A national cross-sectional study on use rates, perceptions, and associated factors.","authors":"Juan S Izquierdo-Condoy, Patricio Naranjo-Lara, Estefanía Morales-Lapo, Alexander Puglla-Mendoza, Marlon R Hidalgo, Andrea Tello-De-la-Torre, Eduardo Vásconez-González, Nathaly Izquierdo-Condoy, David Sánchez-Ordoñez, Galo S Guerrero-Castillo, Raúl F De la Rosa, Paul Vinueza-Moreano, Romina Placencia-André, M Fernanda Díaz, Esteban Ortiz-Prado","doi":"10.18332/tid/187878","DOIUrl":"10.18332/tid/187878","url":null,"abstract":"<p><strong>Introduction: </strong>Electronic cigarettes (e-cigarettes) have emerged as a new paradigm in nicotine delivery systems. Although they are marketed as safer alternatives to tobacco, public perceptions of their safety and utility vary widely. This study aims to understand the percentage of use, factors associated, perceptions, and attitudes about e-cigarettes among Ecuadorian adults.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among the Ecuadorian population aged 18-65 years through a convenience sample, using a structured online questionnaire designed to collect responses from voluntary participants over three months, from February to April 2023. The questionnaire assessed the respondents' attitudes and perceptions towards e-cigarettes. Data were analyzed using descriptive statistics, chi-squared tests, and adjusted logistic regression analyses to identify factors associated with e-cigarette use.</p><p><strong>Results: </strong>Out of a total of 3047 Ecuadorian adults, the percentage of e-cigarette ever use was 27.9% (n=850), with 19.4% being current users and 8.5% former users. A negative stance towards e-cigarettes was predominant, with 66.3% considering e-cigarette use a public health problem in Ecuador. A significant association was observed between e-cigarette use and perceived harmfulness (p<0.001). Among non-users, there was a predominant stance in favor of control measures and disapproval of e-cigarette use among minors (p<0.001). The factors associated with the use of electronic cigarettes included being health personnel (AOR=1.51; 95% CI: 1.26-1.80). Older age (aged >24 years) and a history of tobacco use were associated with lower e-cigarette use (current users, OR=0.31; 95% CI: 0.25-0.38; previous users, OR=0.23; 95% CI: 0.18-0.28).</p><p><strong>Conclusions: </strong>The findings highlight a significant percentage of e-cigarette use among Ecuadorian adults, especially among younger groups. There is a need for comprehensive public health education about e-cigarettes in Ecuador. There is strong support from the public for control measures, suggesting the potential acceptability of regulations concerning e-cigarettes.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of e-cigarette control policies and education in schools on increased legal knowledge, harm perception, susceptibility and e-cigarette use among students in Thailand: A cross-sectional classroom-based survey. 泰国学生对学校电子烟控制政策和教育在增加法律知识、危害认知、易感性和电子烟使用方面的看法:基于课堂的横断面调查。
IF 3.7 4区 医学
Tobacco Induced Diseases Pub Date : 2024-05-30 eCollection Date: 2024-01-01 DOI: 10.18332/tid/187840
Chakkraphan Phetphum, Orawan Keeratisiroj, Atchara Prajongjeep
{"title":"Perception of e-cigarette control policies and education in schools on increased legal knowledge, harm perception, susceptibility and e-cigarette use among students in Thailand: A cross-sectional classroom-based survey.","authors":"Chakkraphan Phetphum, Orawan Keeratisiroj, Atchara Prajongjeep","doi":"10.18332/tid/187840","DOIUrl":"10.18332/tid/187840","url":null,"abstract":"<p><strong>Introduction: </strong>In Thailand, school smoke-free policies initially targeted cigarette smoking but now extend to include electronic cigarettes (e-cigarettes). Yet, the impact of this expansion on curbing e-cigarette use in schools is uncertain. This study seeks to explore how e-cigarette control policies and educational initiatives in Thai secondary schools influence students' legal knowledge, perception of harm, current e-cigarette use, and susceptibility to future use.</p><p><strong>Methods: </strong>This cross-sectional survey was conducted in four regions of Thailand between May and August 2023, involving 6147 students selected through multistage sampling. Data collection utilized a self-reported online questionnaire in Thai, developed using Google Forms. For continuous outcomes, multiple linear regression models assessed relationships between school e-cigarette policy perceptions, covariates, knowledge of e-cigarette laws, and harm perception. Multiple logistic regression models analyzed the association between policy perceptions, covariates, and categorical outcomes: current e-cigarette use and susceptibility.</p><p><strong>Results: </strong>Adjusting for covariates, a positive association was found between students' perceptions of e-cigarette policies and teachings and their knowledge of e-cigarette control laws (B=0.083, p<0.001) and harm perceptions (B=0.491, p<0.001). Additionally, these perceptions were protective against current e-cigarette use (AOR=0.970; 95% CI: 0.95-0.99, p=0.002) and susceptibility among non-users (AOR=0.962; 95% CI: 0.95-0.97; p<0.001).</p><p><strong>Conclusions: </strong>A heightened perception of e-cigarette policies and teachings in schools is associated with increased legal knowledge, heightened harm perception, and a lower likelihood of current or future e-cigarette use. This underscores the importance of enforcing the e-cigarette-free policy in schools to mitigate vaping susceptibility amid the ongoing youth e-cigarette epidemic.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141180751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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