Exposure to secondhand smoke and physical disabilities in non-smokers: A national cross-sectional study with cotinine measurements from NHANES 2013-2018.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tobacco Induced Diseases Pub Date : 2025-02-21 eCollection Date: 2025-01-01 DOI:10.18332/tid/200546

Jiahui He, Zhounan Wu, Yuhang Liang, Jinshen He

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引用次数: 0

Abstract

Introduction: Secondhand smoke (SHS) exposure is a significant health risk, but current research often overlooks its broader impact on functional impairments in the general public.

Methods: This study utilized serum cotinine levels (SCL) from the 2013-2018 NHANES dataset to investigate physical disabilities associated with SHS exposure. SCL represents the combined concentration of cotinine and hydroxycotinine. The physical disabilities assessed include difficulties with hearing, vision, concentration, walking, dressing or bathing independently, and running errands alone. Logistic regression was applied to evaluate the relationship between SCL and physical disabilities in adults, with stratified analyses by age, gender, and race. A p<0.05 was considered significant.

Results: Logistic regression analyses showed that SHS exposure was significantly associated with walking difficulty. Participants in the highest quartile of SCL (Q4) had significantly higher odds of walking difficulty compared to those in the lowest quartile (Q4 vs Q1, AOR=2.03; 95% CI: 1.24-3.31, p-trend=0.010). Higher hydroxycotinine were associated with increased walking difficulty (AOR=1.48; 95% CI: 1.06-2.08, p=0.030). Individuals in the highest quartile of hydroxycotinine (Q4) faced more difficulty running errands (AOR=2.09; 95% CI: 1.13-3.88, p-trend=0.036). Among males, the highest quartiles of cotinine and hydroxycotinine were more strongly associated with walking difficulty than in females (cotinine: AOR=2.92 vs 1.49; hydroxycotinine: AOR=3.23 vs 1.78). In adults aged ≥60 years, higher SCL, cotinine, and hydroxycotinine levels were significantly associated with walking difficulty (SCL, AOR=1.58; 95% CI: 1.24-2.02); cotinine, AOR=1.80; 95% CI: 1.21-2.67; hydroxycotinine, AOR=4.57; 95% CI: 1.92-10.89). An 'L'-shaped association was observed for ln(hydroxycotinine) and walking difficulty, with a significant association beyond -1.306 (AOR=2.57; 95% CI: 1.33-4.96, p=0.005).

Conclusions: Higher SHS is significantly associated with various physical disabilities, especially in men and older adults.

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来源期刊

Tobacco Induced Diseases SUBSTANCE ABUSE-PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

CiteScore

5.30

自引率

5.40%

发文量

审稿时长

12 weeks

期刊介绍： Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community. The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.