Tobacco Induced Diseases最新文献

{"title":"Comparative analysis of global and Chinese trends in the burden of ischemic stroke attributable to secondhand smoke from 1990-2021.","authors":"Xiao Zhou, Jiaming Liu, Xin Li","doi":"10.18332/tid/204510","DOIUrl":"10.18332/tid/204510","url":null,"abstract":"<p><strong>Introduction: </strong>Ischemic stroke (IS) represents a major health burden in China, and tobacco control is recognized as a practical and effective strategy to alleviate this impact. This study examines the influence of secondhand smoke (SHS) on the IS burden in China from 1990-2021.</p><p><strong>Methods: </strong>Based on data from the Global Burden of Disease (GBD) 2021, this study analyzed the mortality and disability-adjusted life years (DALYs) burden of ischemic stroke (IS) attributable to secondhand smoke (SHS) in China and globally from 1990 to 2021. This study examined trends across different age and sex groups and projected future mortality and DALYs, providing a scientific basis for targeted public health strategies.</p><p><strong>Results: </strong>Over the past 32 years, the number of IS deaths from SHS exposure in China rose from 23394.83 (95% UI: 15837.47-32315.19) in 1990 to 53697.88 (95% UI: 35003.84-76382.65) in 2021. Despite this increase, the ASMR declined from 3.94 (95% UI: 2.59-5.54) per 100000 population in 1990 to 2.92 (95% UI: 1.88-4.21) in 2021, with an AAPC of -0.04 (95% CI: -0.04-0.03). However, China's ASMR and ASDR remain significantly higher than the global average. APC analysis revealed greater mortality trends among the elderly and females. Over the next 30 years, mortality rates will decline across all ages, but deaths will rise, especially in those aged 75 years and older.</p><p><strong>Conclusions: </strong>The mortality rate of SHS-related IS in China declined from 1990 to 2021, but elderly and female patients still face a high burden. China's disease burden remains higher than the global average. While mortality rates may continue to decline, deaths are expected to rise, especially among those aged 75 years and older.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The growing public health concern of nicotine pouch consumption among Pakistani youth.","authors":"Rehan Jan, Maryam Jan","doi":"10.18332/tid/205164","DOIUrl":"10.18332/tid/205164","url":null,"abstract":"","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediately scheduled for an appointment to smoking cessation clinics: Key to quitting smoking in chronic airway disease - a multicenter randomized study.","authors":"Dilek Karadoğan, Tahsin Gökhan Telatar, İlknur Kaya, Siahmet Atlı, Neslihan Köse Kabil, Feride Marım, Merve Yumrukuz Şenel, Aycan Yüksel, Burcu Yalçın, Ökkeş Gültekin, Merve Erçelik, Metin Akgün","doi":"10.18332/tid/204254","DOIUrl":"10.18332/tid/204254","url":null,"abstract":"<p><strong>Introduction: </strong>A significant proportion of patients with chronic airway diseases continue to smoke even after the diagnosis. In addition, smoking cessation support continues to be a neglected issue in real-life settings by physicians for that patient group. Therefore, in our search for a solution to this issue, we conducted our study to evaluate the effect of arranging immediate appointments to smoking cessation outpatient clinics on smoking cessation success in patients with chronic airway disease.</p><p><strong>Methods: </strong>This multicenter, randomized, parallel-arm prospective study (NCT05764343) was conducted in pulmonary outpatient clinics between November 2022 and June 2023. Current smoker patients aged ≥18 years diagnosed with COPD, asthma, or bronchiectasis for at least 6 months were included and sequentially randomized in a 1:1 ratio. Both arms received brief smoking cessation interventions, and the intervention arm had immediate access to a smoking cessation clinic appointment. In contrast, the control arm received a standard quitline appointment for routine service. The primary endpoint was the self-reported smoking cessation rate at 3 months, analyzed using an intentionto-treat approach.</p><p><strong>Results: </strong>The study comprised 198 patients in the immediate appointment arm and 199 in the usual care arm. The quit rate was significantly higher in the immediate appointment arm (26.7%) than in the usual care arm (16.5%, p=0.014). Access to smoking cessation medication was 69.3% in the intervention group against 22.0% in the control group (p<0.001). Multivariable analysis identified access to smoking cessation medication as the sole significant predictor of cessation success at 3 months (adjusted odds ratio, AOR=5.64; 95% CI: 2.89-11.03).</p><p><strong>Conclusions: </strong>Our study revealed that access to evidence-based smoking cessation support is positively associated with successful quitting. Compared to the usual care arm, the immediately appointment-scheduled arm has a higher access rate of cessation support. Therefore, smoking cessation support, including pharmacotherapy, should be part of routine care for patients with chronic airway diseases.</p><p><strong>Clinical trial registration: </strong>The study is registered on the official website of ClinicalTrials.gov Identifier: ID NCT05764343.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory response to chronic nicotine-containing electronic cigarette exposure in a rat model of myocardial infarction.","authors":"Jianru Shi, Wangde Dai, Juan Carreno, Jaspreet Sachdeva, Jesus Chavez, Michael T Kleinman, David A Herman, Rebecca J Arechavala, Irene Hasen, Amanda Ting, Robert A Kloner","doi":"10.18332/tid/204010","DOIUrl":"10.18332/tid/204010","url":null,"abstract":"<p><strong>Introduction: </strong>The long-term effects of chronic electronic cigarette (e-cigarette) exposure on lung and heart inflammation during the healing phase of myocardial infarction (MI) remain unexplored. Additionally, the impact of e-cigarette exposure on blood parameters in this context is unclear. This study aims to assess e-cigarette with nicotine (e-cig Nic+) effects on lung histology, inflammatory gene expression in cardiac tissue, and blood parameters during MI recovery.</p><p><strong>Methods: </strong>Sprague Dawley rats of both sexes underwent proximal left coronary artery occlusion to induce a large anterior wall MI. After one week, rats were randomized to either air or e-cig Nic+ exposure for 12 weeks.</p><p><strong>Results: </strong>In the lungs, e-cig Nic+ exposure led to a significant accumulation of inflammatory cells within the alveolar spaces and increased inflammatory cell numbers in the lung parenchyma compared to the air group. Numerically elevated levels of malondialdehyde (MDA), an oxidative stress biomarker, were observed in the e-cig Nic+ group. In the heart, a PCR array analysis of inflammatory cytokines and receptors revealed that 70 out of 84 inflammatory-related genes were downregulated in the e-cig Nic+ group, with 11 reaching statistical significance. Additionally, the blood of rats exposed to e-cig Nic+ exhibited significantly lower white blood cell, lymphocyte, and platelet counts compared to the air group.</p><p><strong>Conclusions: </strong>Chronic exposure to e-cig Nic+ exacerbates lung inflammation, alters inflammatory gene expression in the heart, and suppresses immune cell counts in the blood during MI recovery. These findings suggest that e-cigarette with nicotine aerosol inhalation contributes to lung lesions and dampens immune and inflammatory responses in an already compromised MI setting.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between smoking and the occurrence of hyperuricemia: A retrospective cohort study.","authors":"Peihua Li, Xinyu Li, Guosheng Li, Bing Wang, Yudan Liu, Yuedong Zhao, Qing Yu, Zhengnan Gao, Xuhan Liu","doi":"10.18332/tid/204253","DOIUrl":"10.18332/tid/204253","url":null,"abstract":"<p><strong>Introduction: </strong>A retrospective cohort study was conducted to study the association between smoking and hyperuricemia (HUA).</p><p><strong>Methods: </strong>By collecting and analyzing clinical data of 3196 patients with undiagnosed HUA at baseline in Dalian Municipal Central Hospital of China between 1 January 2010 and 1 January 2021, patients were grouped according to baseline smoking status and smoking index (the number of cigarettes smoked per day × number of years of smoking). Cox regression analysis was used to perform univariable and multivariable analyses of factors that may influence the occurrence of HUA. And further stratification was performed.</p><p><strong>Results: </strong>The median follow-up time was 3.62 years. A total of 485 (15.2%) patients developed HUA (≥420 μmol/L). The incidence of HUA was significantly higher in the smoking group than in the non-smoking group (p<0.05). There was a statistically significant difference in the incidence of HUA between the smoking index 1-4 (>0) groups and the smoking index 0 (0) group (p<0.05). Multifactorial Cox regression analyses were performed separately and after adjustment for relevant influences, the results showed that smoking was an independent risk factor for the occurrence of HUA with a hazard ratio (HR) of 1.38 (95% CI: 1.11-1.72). And the smoking index groups 401-600 and ≥601 were independent risk factors for the occurrence of HUA, with HRs of 1.46 (95% CI: 1.20-1.70) and 1.53 (95% CI: 1.06-2.22), respectively. The further stratified analysis revealed that smoking remained an independent risk factor for the occurrence of HUA in all subgroups, and the smoking index ≥601 group was also an independent risk factor for the occurrence of HUA, with HRs greater than 1 (p<0.05).</p><p><strong>Conclusions: </strong>Smoking is an independent risk factor for the occurrence of HUA and is independent of gender, whether a woman is menopausal, body mass index (BMI), and alcohol consumption. The smoking index ≥601 was an independent risk factor for the occurrence of HUA.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional study of knowledge about secondhand smoke-attributed diseases, awareness, and applicability of the smoking control law in a southern province of Thailand.","authors":"Chutarat Sathirapanya, Napakkawat Buathong, Polathep Vichitkunakorn, Phoomjai Sornsenee, Vasin Pipattanachat, Pornchai Sathirapanya","doi":"10.18332/tid/204397","DOIUrl":"10.18332/tid/204397","url":null,"abstract":"<p><strong>Introduction: </strong>Secondhand smoke (SHS) exposure is a significant cause of illness. This study aimed to explore the awareness of SHS-attributed illnesses and the legal control of the Tobacco Product Control (TPC) Act 2017 among the local people living in Meung district, a municipality of Songkhla Province, Thailand.</p><p><strong>Methods: </strong>This quantitative and qualitative study was conducted in 3 marketplaces and 6 public bus terminals in a southern province of Thailand between November 2021 and September 2022. A total of 330 volunteers were enrolled for the quantitative analysis. Meanwhile, 13 local government officers (LGOs), 2 market visitors, and 5 public vehicle passengers were interviewed for qualitative analysis to evaluate applicability of the law in this province. We collected the participants' general demographics, prevalence of secondhand smoke (SHS) exposure, knowledge about SHS-attributed diseases, and awareness of the law. Chi-squared test was used to assess the associations between demographics and knowledge of SHS-attributed diseases and awareness of the legal restrictions regarding SHS exposure (p<0.05). Thematic analysis for evaluating applicability of the law was conducted from the interviews.</p><p><strong>Results: </strong>Tobacco smell was experienced more frequently than witnessing smokers in marketplaces (49.8% vs 30.0%) and on public vehicles (45.5% vs 20.7%). The mean ± SD scores of knowledge regarding the law were low (marketplace, 4.09 ± 1.61; bus, 4.07 ± 1.69), while that of SHS-attributed health harms were moderate (marketplace, 6.31 ± 2.14; bus, 6.30 ± 1.64). Age, education level, and religion had significant associations with knowledge about SHS-attributed diseases (p=0.001, <0.001, <0.001, respectively), while age and education level were significantly associated with awareness of the law (p<0.001). We found weaknesses in the collaboration of LGOs. Inadequate resources and a high volume of routine workload were the attributed barriers.</p><p><strong>Conclusions: </strong>Enhancing knowledge about SHS-attributed illnesses, awareness of the SHS control law, and strengthening public engagement are crucial for SHS exposure control. The collaboration between the local people and LGOs for effective SHS control is advocated.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of community education on tobacco use among older adults in China.","authors":"Shuang Yu, Yu Liu, Manyi Wang, Yinhe Liang","doi":"10.18332/tid/204512","DOIUrl":"10.18332/tid/204512","url":null,"abstract":"<p><strong>Introduction: </strong>Smoking among older adults is increasingly linked to chronic diseases and higher mortality rates. However, the influence of community education on smoking behavior in older adults remains understudied. This research examines the causal effect of community education on smoking habits of older adults in China.</p><p><strong>Methods: </strong>We use four waves of longitudinal secondary data (2011, 2013, 2015, and 2018) from the China Health and Retirement Longitudinal Study (CHARLS), covering adult children aged 22-58 years and their parents aged ≥60 years. A two-stage least squares (2SLS) model is applied to estimate the causal impact of community education on smoking behaviors among older adults, using exposure to the 1986 Compulsory Schooling Law as an instrumental variable. Mechanism and subgroup analyses are further conducted to validate and interpret the estimated effects.</p><p><strong>Results: </strong>This study includes 26489 adults aged ≥60 years. Community education significantly reduces the likelihood of ever smoking (β= -0.030; 95% CI: -0.048 - -0.012), current smoking (β= -0.020; 95% CI: -0.038 - -0.003), and the number of cigarettes (β= -0.038; 95% CI: -0.075 - -0.001). Mediation analysis indicates that these effects are partially explained by intergenerational support, well-being, and mental health. Among ever smokers, the Center for Epidemiologic Studies Depression Scale (CES-D) score shows the largest indirect effect (β=0.0004; 95% CI: 0.0000-0.0010), accounting for 3.5% of the total effect, followed by contact with children (β= -0.0003; 95% CI: -0.0010 - -0.0000; 1.8%) and optimism (β= -0.0001; 95% CI: -0.0002 - -0.0000; 0.7%). For smoking intensity, CES-D remains the only significant mediator (β=0.0008; 95% CI: -0.0003-0.0010), explaining 4% of the total effect.</p><p><strong>Conclusions: </strong>Community education plays a crucial role in lowering smoking rates among older adults. Policymakers should prioritize educational programs and enhance healthcare services to reduce smoking and improve public health outcomes for aging populations.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impacts on the economy, health, and environment resulting from tobacco cultivation: A cross-sectional survey of tobacco farmer perspectives in Thailand.","authors":"Chakkraphan Phetphum, Raphael Lencucha","doi":"10.18332/tid/204301","DOIUrl":"10.18332/tid/204301","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco cultivation is associated with financial instability, health risks, and environmental degradation. While Thailand has made progress in tobacco control, challenges remain in supporting farmers with sustainable alternatives. This study examined the perceived economic, health, and environmental impacts of tobacco cultivation among Thai tobacco farmers.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted from October 2021 to January 2022 in Chiang Mai, Phrae, and Sukhothai, the major tobacco-growing provinces in Thailand. A total of 1505 tobacco farmers completed self-administered questionnaires. The instrument measured perceived impacts on a 3-point Likert scale (low to high). Frequencies and proportions for descriptive statistics are reported along with adjusted odds ratios and 95% confidence intervals for logistic regression models.</p><p><strong>Results: </strong>Economic impacts were most frequently reported (43.7%), particularly increased debt (47.6%) and income loss (43.5%). Health impacts (31.6%) included symptoms of Green Tobacco Sickness (47.2%) and reduced work capacity (29.9%). Environmental concerns (14.4%) included pesticide contamination (10.8%) and degradation of soil and water resources (10.6%). Higher economic impact was associated with cultivating Virginia tobacco (AOR=6.51; 95% CI: 4.90-8.63), higher level of education (AOR=1.39; 95% CI: 1.01-1.92), contract farming (AOR=1.27; 95% CI: 0.99-1.63), and farming experience (AOR=1.00; 95% CI: 0.99-1.01). Health impact was associated with age (AOR=1.04; 95% CI: 1.03-1.05), land rental (AOR=0.75; 95% CI: 0.58-0.98), female gender (AOR=0.74; 95% CI: 0.58-0.94), and Virginia cultivation (AOR=0.32; 95% CI: 0.23-0.44). Environmental impact was linked to labor hiring (AOR=2.68; 95% CI: 1.41-5.07) and land rental (AOR=0.56; 95% CI: 0.39-0.79).</p><p><strong>Conclusions: </strong>Thai tobacco farmers face significant economic, health, and environmental burdens. Policy interventions should promote sustainable alternatives to mitigate these impacts.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The global burden of bladder, kidney, and prostate cancers attributable to smoking from 1990 to 2021 and projections for the next two decades: A cross-sectional study.","authors":"Xiangyu Chen, Xuexue Hao, Jinhao Wu, Xiaoqiang Liu","doi":"10.18332/tid/204299","DOIUrl":"10.18332/tid/204299","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Smoking increases the risk of bladder and kidney cancers and is associated with a poorer prognosis in prostate cancer (PCa) patients, which poses a significant health and socioeconomic burden. Understanding the epidemiologic trends of urological cancers attributable to smoking is critical to developing targeted prevention strategies. This study examines global trends in the three urological cancers attributable to smoking from 1990 to 2021 and projects future trends over the next two decades.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Data were obtained from the Global Burden of Disease (GBD) 2021. Metrics included deaths, disability-adjusted life years (DALYs), age-standardized mortality rates (ASMR), and age-standardized DALY rates (ASDR), with uncertainty intervals (UIs). Burden comparisons were stratified by sex, age, and sociodemographic index (SDI). Temporal trends were analyzed using Joinpoint regression to calculate annual percentage change (APC) and average annual percentage change (AAPC), with 95% confidence intervals (CIs). Future trends were predicted using the autoregressive integrated moving average (ARIMA) model.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Compared with 1990, the number of deaths of bladder cancer, kidney cancer and PCa attributable to smoking increased by 43%, 67%, and 31%, and the number of DALYs increased by 31%, 52%, and 29% in 2021. However, the corresponding age-standardized rates showed a downward trend (AAPC&lt;sub&gt;ASMR of bladder cancer&lt;/sub&gt;, -1.53; AAPC&lt;sub&gt;ASDR of bladder cancer&lt;/sub&gt;, -1.68; AAPC&lt;sub&gt;ASMR of kidney cancer&lt;/sub&gt;, -0.89; AAPC&lt;sub&gt;ASDR of kidney cancer&lt;/sub&gt;, -1.11; AAPC&lt;sub&gt;ASMR of PCa&lt;/sub&gt;, -2.10; AAPC&lt;sub&gt;ASDR of PCa&lt;/sub&gt;, -1.97). The burden was higher among males than females, with the highest burden observed in high-SDI regions. The ASMR and ASDR were found to have a non-linear positive correlation with SDI (RASMR of bladder cancer=0.574, p&lt;0.001; R&lt;sub&gt;ASDR of bladder cancer&lt;/sub&gt;=0.580, p&lt;0.001; R&lt;sub&gt;ASMR of kidney cancer&lt;/sub&gt;=0.792, p&lt;0.001; R&lt;sub&gt;ASDR of kidney cancer&lt;/sub&gt;=0.783, p&lt;0.001; R&lt;sub&gt;ASMR of PCa&lt;/sub&gt;=0.417, p&lt;0.001; R&lt;sub&gt;ASDR of PCa&lt;/sub&gt;=0.436, p&lt;0.001), although the greatest improvements over the past three decades were observed in high-SDI regions. Joinpoint regression analysis indicated a downward trend in global deaths and DALYs burden, and the ARIMA model predicted that the burden of related diseases will continue to decline through 2041 (ASMR&lt;sub&gt;bladder cancer&lt;/sub&gt;=0.44; ASDR&lt;sub&gt;bladder cancer&lt;/sub&gt;=8.56; ASMR&lt;sub&gt;kidney cancer&lt;/sub&gt;=0.13; ASDR&lt;sub&gt;kidney cancer&lt;/sub&gt;=2.82; ASMR&lt;sub&gt;PCa&lt;/sub&gt;=0.28; ASDR&lt;sub&gt;PCa&lt;/sub&gt;=4.28).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Smoking has imposed a substantial disease burden on urological cancers over the past three decades. While overall ASDR and ASMR are declining, the disease burden remains high among men, especially those in high-SDI areas. This emphasizes the need for increased tobacco control for these pop","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of smoking cessation outcomes in patients with cardiovascular disease: A retrospective cohort study from Türkiye.","authors":"Yagmur Gokseven Arda, Guzin Zeren Ozturk","doi":"10.18332/tid/203867","DOIUrl":"10.18332/tid/203867","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular disease (CVD) is a major preventable cause of mortality, and smoking cessation significantly reduces the risk of recurrent cardiovascular events. However, many patients continue smoking despite their CVD diagnosis. This study aims to evaluate the impact of CVD and associated factors on smoking cessation success in patients who attempted to quit smoking at least one year ago.</p><p><strong>Methods: </strong>This retrospective cohort study included patients who applied to the Smoking Cessation Clinic (SCC) between 1 May 2022 and 30 April 2023. A total of 539 eligible patients were analyzed. Data on demographics, CVD status, Fagerström test for nicotine dependence score, treatment modality (bupropion, nicotine replacement therapy, behavioral counseling), and smoking cessation outcomes were collected from medical records and confirmed via telephone interviews. Smoking cessation success was defined as complete abstinence after one year.</p><p><strong>Results: </strong>Among the participants, 145 (26.9%) had a history of CVD. The overall self-reported smoking cessation success rate after one year was 16.7%, and 17.2% in the CVD group. Bupropion users had significantly higher treatment completion rates (p=0.015). Multivariable logistic regression analysis revealed that older age (AOR=1.03; 95% CI: 1.01-1.05), higher level of education (AOR=1.84; 95% CI: 1.03-3.26), lower nicotine dependence score (AOR=0.85; 95% CI: 0.77-0.94), and treatment completion (AOR=0.13, 95% CI: 0.07-0.23) were significantly associated with smoking cessation success in the total sample. Among patients with CVD, older age (AOR=1.06; 95% CI: 1.01-1.12) and treatment completion (AOR=0.15; 95% CI: 0.05-0.43) were also associated with higher cessation success. Patients with CVD were more likely to receive non-pharmacological interventions, and behavioral counseling alone showed the highest success rate (25.0%).</p><p><strong>Conclusions: </strong>Older age and treatment adherence were significantly associated with smoking cessation success, yet overall cessation rates remained low. A CVD diagnosis alone did not significantly enhance success, highlighting the need for tailored behavioral support and structured follow-up. Optimizing cessation programs with individualized interventions may improve outcomes, particularly in high-risk CVD patients.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}