Reviews and Research in Medical Microbiology最新文献_第6页

Prevalence study of different methods for hepatitis B virus diagnosis with blood donor people in Baghdad city 巴格达市献血者不同乙肝病毒诊断方法的流行病学研究

Reviews and Research in Medical Microbiology Pub Date : 2021-04-09 DOI: 10.1097/MRM.0000000000000277

N. A. A. A. H. Saeed, I. H. Hamzah, Israa M. S. Al-Kadmy

{"title":"Prevalence study of different methods for hepatitis B virus diagnosis with blood donor people in Baghdad city","authors":"N. A. A. A. H. Saeed, I. H. Hamzah, Israa M. S. Al-Kadmy","doi":"10.1097/MRM.0000000000000277","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000277","url":null,"abstract":"Background: Globally, infecting with hepatitis B virus (HBV) is a big issue today. The present study was aimed to assess the prevalence and year-wise trend of the HBV surfaces antigens (HBs-Ag), antibodies vs. HBV core antigens (anti-HBcs) while HBV-DNA in serum sample patients and replacement blood donors in Baghdad, Iraq. Methods: During the period between 2017 and 2019, a total of 212 blood donors of ages 18–70 years were screened for HBs-Ag, anti-HBs by enzyme-linked immunosorbent assay (ELISA) technique, and anti-HBc antigen–antibody (Ag–Ab) and HBV-DNA using real-time PCR. Results: A total of 110 (51.8%) of 212 blood donors were positive to all tests: HBs-Ag, anti-Hbs, anti-HBc and HBV-DNA. Forty-six (41.8%) were positive for HBV-DNA, HBs-Ag and anti-HBc, whereas 14 (12.7%) were positive for HBs-Ag and anti-HBc. Although nine (8.1%) blood donors were positive in real-time PCR (HBV-DNA loaded) with a negative result in ELISA. Forty one (37.2%) markers indicated a high number of inveterate or resolvable contagion. The total diffusion increment significance in 2017–2018, stabilized thereafter and started decreasing from 2018 to 2019 marginally. There is a high significance variance at (P < 0.01) while comparison among examined groups. Conclusions: Significance and impact of study: the prevalence of HBV infection in 3 years is lower in Baghdad blood donors (51.8%) compared to other regions of Iraq. A high number of infections with no signs of HBs-Ag or viral DNA were recorded. Therefore, the inclusion of anti-HBc seromarker and DNA in the routine screening could isolate potential infectious blood units.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127353677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of gut microbiota in the treatment of irritable bowel syndrome 肠道菌群在肠易激综合征治疗中的作用

Reviews and Research in Medical Microbiology Pub Date : 2021-03-23 DOI: 10.1097/MRM.0000000000000284

H. Ebrahimzadeh Leylabadlo, F. S. Heravi, Elghar Soltani, A. Abbasi, H. Kafil, M. Parsaei, S. Sanaie, Zainab Ahmadian, R. Ghotaslou

{"title":"The role of gut microbiota in the treatment of irritable bowel syndrome","authors":"H. Ebrahimzadeh Leylabadlo, F. S. Heravi, Elghar Soltani, A. Abbasi, H. Kafil, M. Parsaei, S. Sanaie, Zainab Ahmadian, R. Ghotaslou","doi":"10.1097/MRM.0000000000000284","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000284","url":null,"abstract":"Irritable bowel syndrome (IBS) is known as a functional gastrointestinal disorder that has different effects on the large intestine and caused malfunction of bowel and colon tissues, which leads to chronic diarrhea, constipation, abdominal pain, cramps, and bloating. Genetic pre determinants and environmental factors including; stress, age, diet, geographical features, use of antibiotics, and more importantly gut microbiota (GM) are implicated in the development of IBS. In the present review, by using free search engines providing biomedical and clinical literature (Science Direct, PubMed, and Google Scholar) we have evaluated the association of GM and IBS and the role of human interventions such as probiotics, synbiotic, prebiotics, and the fecal microbiota transplantation (FMT) as potential therapeutic methods within the treatment of IBS. Current advances in molecular approaches have broadened our understanding of GM and the significant impact of microbial communities on human wellbeing. The imbalanced distribution of microbial communities resides in the human intestine (intestinal dysbiosis) has been associated with IBS development. Due to current challenges in the treatment of IBS, various manipulation of the GM as a new approach for IBS remedy has attracted much attention in recent years. Hence, scientific literature confirms that the manipulation of GM with prebiotic, probiotic, and synbiotic interventions as well as FMT can significantly improve the GM composition/balances and prevent negative effects of dysbiosis GM in patients with symptoms of IBS.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124105095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Epidemiology of integrons among multidrug-resistant pathogens; an Asian update 多重耐药病原菌整合子的流行病学研究亚洲更新

Reviews and Research in Medical Microbiology Pub Date : 2021-03-19 DOI: 10.1097/MRM.0000000000000270

Maryam Najafi, Maryam Omidvar-Panah, F. Nikkhahi, A. Peymani

引用次数: 2

A review of brucellosis in the Middle East and control of animal brucellosis in an Iranian experience 回顾中东布鲁氏菌病和伊朗动物布鲁氏菌病的控制经验

Reviews and Research in Medical Microbiology Pub Date : 2021-03-19 DOI: 10.1097/MRM.0000000000000266

N. Bahmani, A. Bahmani

{"title":"A review of brucellosis in the Middle East and control of animal brucellosis in an Iranian experience","authors":"N. Bahmani, A. Bahmani","doi":"10.1097/MRM.0000000000000266","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000266","url":null,"abstract":"To describe brucellosis infectious as a zoonotic disease, which is caused by Brucella spp. Brucellosis is considered to be a major health and economic challenge in developing countries, including Iran. This study focuses on epidemiology human's and animal's brucellosis and disease control strategies. Test-and-slaughter technique and extensive livestock vaccination programs are used for eradication of brucellosis. Test-and-slaughter is a general policy in Middle Eastern countries to eradicate the disease. Under this program, the Rose Bengal plate test is used as a screening measure to identify the infected herd, whereas the complement fixation test is applied as a confirmatory test. The prevalence of bovine brucellosis in 2015–2016 ranged between 7.2 and 18.1% in Kuwait and Jordan and ranged between 3 and 3.1% in Iraq and Iran in 2012–2014. Prevalence of goat brucellosis (Brucella melitensis) was 3.5% in Iran in 2014. Test-and-slaughter is used in most of the countries where the prevalence rate of the disease does not exceed 2%. Since 1963, testing the vaccine efficacy in goats and sheep has proven that vaccination can decrease the epidemic rate of the disease from 45 to 1.8%. This study indicated the test-and-slaughter technique alone has not proven successful in the eradication of brucellosis in Iran, and animal vaccination is essential to the control and eradication of animal and human brucellosis.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126140035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Extragastric infection of Helicobacter pylori and alopecia areata: a systematic review and meta-analysis 幽门螺杆菌胃外感染与斑秃:一项系统综述和荟萃分析

Reviews and Research in Medical Microbiology Pub Date : 2021-03-11 DOI: 10.1097/MRM.0000000000000276

K. Ghazvini, Y. Yamaoka, M. Karbalaei, M. Keikha

{"title":"Extragastric infection of Helicobacter pylori and alopecia areata: a systematic review and meta-analysis","authors":"K. Ghazvini, Y. Yamaoka, M. Karbalaei, M. Keikha","doi":"10.1097/MRM.0000000000000276","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000276","url":null,"abstract":"Alopecia areata is an autoimmune cutaneous disease, and the involved mechanism in its pathogenesis has not yet been properly identified. Based on the available evidences, the prevalence of alopecia areata is more common than other autoimmune disorders that caused by Helicobacter pylori infection such as autoimmune thyroiditis, psoriasis, celiac, and Sjogren's syndrome. In addition, previous published reports have shown that antibiotic therapy can cure alopecia areata. Hence, it seems that there is a probable relationship between infection with H. pylori and alopecia areata. In general, the main purpose of this study was to statistically evaluate the infection with this bacterium and its progression to alopecia areata. Because, the available documents had controversial results, we evaluated the data from 926 cases to investigate the relationship between infection with H. pylori and alopecia areata. According to our statistical analysis, we found that the incidence of H. pylori infection among alopecia areata cases is high, also our findings revealed that there is significant association between H. pylori infection and susceptibility to alopecia areata (odds ratio: 1.57; 1.19–2.05 with 95% confidence intervals). Based on the current results, H. pylori infection can be considered as a risk factor for alopecia areata development.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126461696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Bacterial and viral zoonotic infections: bugging the world 细菌和病毒人畜共患感染:困扰世界

Reviews and Research in Medical Microbiology Pub Date : 2021-02-16 DOI: 10.1097/MRM.0000000000000273

Elham Sheykhsaran, Nima Hemmat, H. Leylabadlo, Hossein Bannazadeh Baghi

{"title":"Bacterial and viral zoonotic infections: bugging the world","authors":"Elham Sheykhsaran, Nima Hemmat, H. Leylabadlo, Hossein Bannazadeh Baghi","doi":"10.1097/MRM.0000000000000273","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000273","url":null,"abstract":"The zoonoses infectious diseases can be naturally transmitted between usually vertebrate animals and humans. The dispersion of zoonotic diseases varies greatly depending on geographical factors. For involved organisms in different regions, the severity and epidemiology are not considered to be the same for all infections. In the incidence procedure, animals and human act as an intermediate or final host. It is concluded that bacteria and viruses are the most widely known agents of zoonotic infections and cause a series of major diseases, such as anthrax, plague, brucellosis, rabies, Crimean–Congo hemorrhagic fever, Zika virus, and so on. Major modern diseases such as Ebola and salmonellosis are big medical concerns. Mammals and arthropods serve as reservoirs and vectors in the transmission cycle of infections to humans. Furthermore, zoonotic infections have different forms of transmission including direct modes such as influenza and rabies. Transmission can also occur through the intermediate species as vectors, which carry the causative pathogen without getting infected. A reverse zoonosis or anthroponosis occurred when humans infect the animals. In case of inappropriate treatment, the mortality rate would be increasingly high in zoonotic-infected patients. To deal with these infections, and reduce their impact, the WHO suggests some very basic policies. Scheduled plans, reducing contact with animals, and protective coatings in the endemic regions, are the fundamental measures for the reduction of outbreaks and the severity of zoonotic diseases.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120911668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Can Helicobacter pylori serve as a trigger for oral lichen planus? 幽门螺杆菌可以作为口腔扁平苔藓的诱因吗?

Reviews and Research in Medical Microbiology Pub Date : 2021-02-16 DOI: 10.1097/MRM.0000000000000269

H. Moravvej, M. Shahidi-Dadras, H. Memariani, M. Memariani, R. Robati, M. Gheisari

引用次数: 1

Frequency of underlying diseases, symptoms and mortality rate of COVID-19: a systematic review and meta-analysis COVID-19的基础疾病频率、症状和死亡率:系统综述和荟萃分析

Reviews and Research in Medical Microbiology Pub Date : 2021-02-04 DOI: 10.1097/MRM.0000000000000262

M. Shams, G. Basati, G. Kalvandi, A. Abdoli, H. Tavan

{"title":"Frequency of underlying diseases, symptoms and mortality rate of COVID-19: a systematic review and meta-analysis","authors":"M. Shams, G. Basati, G. Kalvandi, A. Abdoli, H. Tavan","doi":"10.1097/MRM.0000000000000262","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000262","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is known to be affected by underlying diseases of the respiratory system. In this meta-analysis, the keywords of COVID-19, underlying diseases, symptoms, and mortality were searched in national and international databases to obtain the related studies. The inclusion criteria were as follows: interventional, clinical, descriptive and cross-sectional, and studies focusing on COVID-19. This study was conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol. Eighteen studies were selected to be finally analyzed. The mean percentage of mortality was 14% (I2 = 98.9, P < 0.001). The most common symptoms were fever (91%, I2 = 88.5, P < 0.001) and cough (71%, I2 = 84.5, P < 0.001), and the most frequent underlying diseases were hypertension (41%, I2 = 98.9, P < 0.001), diabetes mellitus (18%, I2 = 88.7, P < 0.001) and cardiovascular disease (11%, I2 = 87.7, P < 0.001). Findings of present study suggest that individuals with underlying diseases have a higher rate of mortality following COVID-19 infection.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127824190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The association between diversity and composition of vaginal microbiota of Iranian women with and without human papillomavirus infection 感染和不感染人乳头瘤病毒的伊朗妇女阴道微生物群的多样性和组成之间的关系

Reviews and Research in Medical Microbiology Pub Date : 2021-01-19 DOI: 10.1097/MRM.0000000000000257

Rosa Behboodi, Shirin Hashemi, S. Javadi, Roghayeh Ghaniabadi, N. Mohammadzadeh, S. Razavi

{"title":"The association between diversity and composition of vaginal microbiota of Iranian women with and without human papillomavirus infection","authors":"Rosa Behboodi, Shirin Hashemi, S. Javadi, Roghayeh Ghaniabadi, N. Mohammadzadeh, S. Razavi","doi":"10.1097/MRM.0000000000000257","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000257","url":null,"abstract":"Objective: Cervical intraepithelial neoplasia (CIN) and cervical adenocarcinoma are the most common human papillomavirus (HPV)-related diseases. The present study is aimed at examining the association between diversity and composition of vaginal microbiota in HPV-positive and HPV-negative Iranian women by quantitative PCR. Method: In this study, 69 vaginal samples with and without manifestation of HPV were obtained from women referring to a gynecology clinic and extracted DNA was introduced to real-time PCR looking for the HPV serotypes and bacterial load by using bacterial 16S rRNA gene. Results: Out of 64 samples, 16 isolates were normal, 13 isolates were clearance or HPV-negative, and 16 isolates were persistence or HPV-positive. Lactobacillus spp. is the predominant vaginal microbiota in normal women and its count became lower at HPV-negative and finally became zero at HPV-positive group. We could approve a significant increase in the colony count of Bacteroides, and Bifidobacteria in HPV 16 group. The statistical analysis did not show any significant association between the frequency or presence of each bacterium and the types of cervical cell abnormalities (P value <0.05). Conclusion: Despite the vaginal bacteria were more frequent among patients with HPV and low-grade squamous intraepithelial lesion (LSIL), it was not statistically significant.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121354592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of arginine metabolism with neurodegenerative diseases in infected cells with herpes simplex virus-1 单纯疱疹病毒-1感染细胞精氨酸代谢与神经退行性疾病的相关性

Reviews and Research in Medical Microbiology Pub Date : 2021-01-19 DOI: 10.1097/MRM.0000000000000264

Saleh Jamehdor, M. H. Sangtarash, S. Farivar, R. Amini, A. Teimoori

{"title":"Correlation of arginine metabolism with neurodegenerative diseases in infected cells with herpes simplex virus-1","authors":"Saleh Jamehdor, M. H. Sangtarash, S. Farivar, R. Amini, A. Teimoori","doi":"10.1097/MRM.0000000000000264","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000264","url":null,"abstract":"Arginine is a semiessential amino acid in human. Metabolism of arginine in human plays a key role in the production of proline, polyamines, urea, creatine, glutamate, ornithine, citrulline, agmatine and nitric oxide. Metabolism of this amino acid changes in neurodegenerative diseases. Association between herpes simplex virus-1 (HSV-1) infection and the probability of developing neurodegenerative diseases in humans has been proven, but the association between the molecular mechanism of HSV-1 infected cells and increased risk of these diseases has not been determined. Human embryonic kidney 293 (HEK 293) cells were cultured and checked for mycoplasma bacterial infection with polymerase chain reaction (PCR) technique, then the cells were divided into two groups. One group of cells became infected with multiplicity of infections 1 and 5 (MOIs 1 and 5) HSV-1 and the other group considered as a control. After 6.5 h, the cells were collected and RNA extracted, then cDNA synthesized, and changes in mRNA expression of key arginine metabolism enzymes genes were investigated with real-time PCR and data were analyzed by using REST 2009 (Corbett Research, United Kingdom) software. The aim of this study was to investigate the expression of the arginine metabolism pathway key enzymes in HEK 293 cells infected with HSV-1 and the interaction probability with neurodegenerative diseases. In this study, it has been shown that most of the key enzymes involved in arginine metabolism in HEK 293-infected cells with HSV-1 has changed in MOIs 1 and 5. These changes are great along with changes in neurodegenerative diseases. Change in arginine metabolism key enzymes mRNA expression after infection with HSV-1 can reflect one of the most important mechanisms of HSV-1 involvement in neurodegenerative diseases.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122014476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0