Reviews and Research in Medical Microbiology最新文献_第8页

Detection of qnrA, qnrB, and qnrS genes in Klebsiella pneumoniae and Escherichia coli isolates from leukemia patients 白血病患者肺炎克雷伯菌和大肠杆菌分离株qnrA、qnrB和qnrS基因的检测

Reviews and Research in Medical Microbiology Pub Date : 2020-11-23 DOI: 10.1097/MRM.0000000000000250

Mahdane Roshani, A. Goodarzi, A. Hashemi, Farhad Afrasiabi, H. Goudarzi, M. Arabestani

{"title":"Detection of qnrA, qnrB, and qnrS genes in Klebsiella pneumoniae and Escherichia coli isolates from leukemia patients","authors":"Mahdane Roshani, A. Goodarzi, A. Hashemi, Farhad Afrasiabi, H. Goudarzi, M. Arabestani","doi":"10.1097/MRM.0000000000000250","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000250","url":null,"abstract":"The frequency of plasmid-mediated quinolone resistance (PMQR) in Escherichia coli and Klebsiella pneumoniae clinical isolates is a serious issue in patients with leukemia. One of the critical factors implicated in this resistance manner may be genes encoding enzymes producing the protecting effect against quinolone-based antibiotics. The goal of this study was to determine the prevalence of E. coli and K. pneumoniae encoding the qnrA, qnrB, and qnrS enzymes genes in isolates from patients with leukemia in Tehran. Eighty E. coli and K. pneumoniae isolates were collected from patients with leukemia admitted to hospitals of Tehran. PCR technique was used to detect qnrA, qnrB, qnrS genes. The prevalence of qnrA, qnrB, and qnrS genes was 22.5, 26.75, and 46.25%, respectively. This study indicated that the high frequency of antibiotic resistance, qnrA, qnrB, and qnrS-producing E. coli and K. pneumoniae isolates, could be a major concern and further studies are needed for infection control measures in the patients affected by leukemia disease in Iran.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"36 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129340694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A review on an ongoing pandemic caused by the severe acute respiratory syndrome coronavirus 2: the pathogenesis, epidemiology, immunological features, and currently available diagnostic tests 严重急性呼吸综合征冠状病毒2型引起的持续大流行:发病机制、流行病学、免疫学特征和现有诊断检测方法综述

Reviews and Research in Medical Microbiology Pub Date : 2020-08-31 DOI: 10.1097/MRM.0000000000000248

S. Ohadian Moghadam

引用次数: 0

SARS-CoV-2 receptor ACE2 and molecular pathway to enter target cells during infection SARS-CoV-2受体ACE2与感染过程中进入靶细胞的分子途径

Reviews and Research in Medical Microbiology Pub Date : 2020-08-31 DOI: 10.1097/MRM.0000000000000237

K. Najafi, Parham Maroufi, E. Khodadadi, Elham Zeinalzadeh, K. Ganbarov, M. Asgharzadeh, H. Kafil

{"title":"SARS-CoV-2 receptor ACE2 and molecular pathway to enter target cells during infection","authors":"K. Najafi, Parham Maroufi, E. Khodadadi, Elham Zeinalzadeh, K. Ganbarov, M. Asgharzadeh, H. Kafil","doi":"10.1097/MRM.0000000000000237","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000237","url":null,"abstract":"Novel Covid-19 (Sars-CoV-2) is a leading acute respiratory tract infection in humans and respiratory disease COVID-19 has gained global resonance, and attempts are being made to classify the molecular characteristics and evolutionary background of this virus. SARS-CoV-2 infects host cells via a variable molecular mechanism. Thus, the rapid and reliable diagnosis of pathogenic viruses plays a crucial role in finding the right treatments, saving lives, and stopping epidemics. that binds to host receptors and fuses viral and cell membranes. This review summarizes the information currently available about the seven HCoVs, with a focus on comparing and contrasting the various HCoVs from a virus evolution and genome recombination perspective. The cause for the angiotensin 2 receptor being an enzyme-converting site is also emphasized. This study sets out to shed light on the SARS-CoV-2 and the main entrance pathways into target cells. This is expected to help researchers and clinicians develop new methods to diagnose coronavirus infection in a timely and efficient manner.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116627887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The antibacterial effect of infantile fecal Lactobacillus against Escherichia coli causing healthcare-associated infection 婴儿粪便乳酸菌对引起保健相关感染的大肠杆菌的抗菌作用

Reviews and Research in Medical Microbiology Pub Date : 2020-08-31 DOI: 10.1097/MRM.0000000000000244

M. Abdi, A. Davoodabadi, M. M. Soltan Dallal

{"title":"The antibacterial effect of infantile fecal Lactobacillus against Escherichia coli causing healthcare-associated infection","authors":"M. Abdi, A. Davoodabadi, M. M. Soltan Dallal","doi":"10.1097/MRM.0000000000000244","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000244","url":null,"abstract":"Background: Healthcare-associated infections (HAIs) are a major public health problem worldwide. Increasing resistance of HAIs agents to conventional antibiotics also becomes a major therapeutic challenge for physicians. The aim of this research was to determine the antibacterial properties of Lactobacillus plantarum and Lactobacillus fermentum isolated from the stool of healthy infants against Escherichia coli causing HAI. Methods: Healthy infantile fecal samples and HAIs-origin samples (urine, blood, and etc.) were collected. Phenotypic isolation and characterization were done. Genotypic identification of lactic acid bacteria was performed by 16S rRNA gene sequencing. The antibiotic susceptibility test was performed using disc diffusion method. Antagonistic effect of Lactobacillus strains by well diffusion method. Results: Of 105 HAI-origin isolates, 25 were identified as E. coli., L. plantarum, and L. fermentum had more probiotic potential. E. coli isolates showed high resistance to Ceftriaxone, Cotrimoxazole, and Ciprofloxacin. Examined Lactobacillus species showed a significant inhibitory effect against E. coli isolates. Conclusion: L. plantarum had considerable inhibitory activity against E. coli isolates with HAIs-origin that were resistant to the most conventional antibiotics.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121471060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reviews and Research in Medical Microbiology Pub Date : 2020-08-31 DOI: 10.1097/MRM.0000000000000238

N. Bolourchi, O. Azizi, Amir Mohammad Ali Tabrizi, Saber Esmaeili, Sepideh Fereshteh, F. Badmasti

{"title":"Clonal relatedness of Acinetobacter baumannii isolated from the Middle East: a systematic review","authors":"N. Bolourchi, O. Azizi, Amir Mohammad Ali Tabrizi, Saber Esmaeili, Sepideh Fereshteh, F. Badmasti","doi":"10.1097/MRM.0000000000000238","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000238","url":null,"abstract":"Supplemental Digital Content is available in the text Determination of clonal relatedness among Acinetobacter baumannii strains at region level is an important epidemiological issue. In this systematic review, we analyzed 33 MLST-based studies (both Oxford and Pasteur MLST schemes) conducted in the Middle East. This study showed that multidrug-resistant ST2Pas (belonging to CC2), ST195Ox, and ST208Ox (both belonging to CC92) have been repeatedly reported from numerous Middle Eastern countries. In the Pasteur scheme, blaVIM and blaIMP as carbapenmase genes have been mainly detected from Saudi Arabia. Moreover, blaOXA-58 encoding sequence types were from Turkey (ST2, ST109, and ST84) and Saudi Arabia (ST19, ST20, ST196, ST194). On the other hand, an analysis of the Oxford scheme revealed that there were five major clonal complexes, including CC218, CC109, CC99, CC236, and CC1151. Egyptian sequence types were the main producers of blaNDM, blaVIM, and blaKPC. This study indicates that highly visited countries in this region have an important role in the distribution of major carbapenemase genes. These countries effectively involved in the expansion and circulation of multidrug-resistant sequence types throughout the Middle East.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124235206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Prevalence of human trichostrongyliasis in Iran: a systematic review and meta-analysis 伊朗人毛圆线虫病的流行:系统回顾和荟萃分析

Reviews and Research in Medical Microbiology Pub Date : 2020-06-30 DOI: 10.1097/MRM.0000000000000231

B. Rahimi-esboei, M. Pourhajibagher, A. Bahador

{"title":"Prevalence of human trichostrongyliasis in Iran: a systematic review and meta-analysis","authors":"B. Rahimi-esboei, M. Pourhajibagher, A. Bahador","doi":"10.1097/MRM.0000000000000231","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000231","url":null,"abstract":"Trichostrongylus is one of the most common helminth parasites, with a wide global distribution. It is the causative agent of trichostrongyliasis infection, which is prevalent in humans and other ruminants. These parasites are the main cause of mortality and morbidity. The infection is mainly contracted by ingesting larvae at the infective stage. In this study, we aimed to identify the prevalence rate of Trichostrongylus infection in the Iranian general population to progress to a complete description of the disease situation in Iran for future use. English and Persian databases, such as PubMed, Science Direct, Web of Science, Scopus, and Google Scholar are the English databases and Magiran, Scientific Information Database, Iran Medex, and Iran Doc, as well as dissertations of graduate student was searched. Our search resulted in 18 reports published between 1984 and 2015, including 13 published in Persian and five in English. The random errors method was used for this meta-analysis. The result reveals that the overall seroprevalence rate of Trichostrongylus in the general population in Iran was 10% (95% confidence interval = 1.6–17%). A significant linear trend of increasing overall prevalence by age was noted (P < 0.0001). According to our knowledge, this is the first systematic review of Trichostrongylus infection in Iran. The results indicate that the prevalence of Trichostrongylus infection in Iran is 0.01%. Based on these findings, increasing animal research and epidemiologic studies in Iran is important to prevent and control zoonotic parasites.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116334200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1