Reviews and Research in Medical Microbiology最新文献_第2页

Thromboembolism: the secret lethal weapon of coronavirus disease 2019 血栓栓塞:2019冠状病毒病的秘密致命武器

Reviews and Research in Medical Microbiology Pub Date : 2023-01-11 DOI: 10.1097/MRM.0000000000000336

A. K. Ahmed, Eslam R. Moustafa, Aya M. Abd EL-Monem, Galal A. Hasan, O. A. Mohamed, Islam H. Ibrahim, G. Batiha, Israa M. S. Al-Kadmy, Amal Hosni, H. Hetta

{"title":"Thromboembolism: the secret lethal weapon of coronavirus disease 2019","authors":"A. K. Ahmed, Eslam R. Moustafa, Aya M. Abd EL-Monem, Galal A. Hasan, O. A. Mohamed, Islam H. Ibrahim, G. Batiha, Israa M. S. Al-Kadmy, Amal Hosni, H. Hetta","doi":"10.1097/MRM.0000000000000336","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000336","url":null,"abstract":"Covid-19 (COVID-19) is a pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began in Wuhan, China, and spread globally in the last few months. COVID-19 pandemic affects anticoagulation, in most patients who need regular anticoagulant care, not just those infected with (SARS-CoV-2). In patients with COVID-19, coagulopathy causes morbidity and mortality. Yet the mechanisms are uncertain and there are few biomarkers. Venous thromboembolism, a possible reason for unexplained mortality, has often been documented in cases of COVID-19, but because of the complexities of antithrombotic treatment and coagulation disorders, its management is still challenging. So, because of the emergency of the COVID-19 pandemic and the unknown risks about its coagulopathy management, we intended to provide such a literature review on the potential blood clotting disorder mechanisms, the unique characteristics of COVID-19 coagulopathy, the effect of heparin in COVID-19, prevention and risk assessment for venous thromboembolism, anticoagulation management in venous thromboembolism, diagnosis and treatment of thromboembolism, and thrombolytic therapy in pregnancy in COVID-19. Here, our overview may provide useful information for physicians to enable them to manage COVID-19 coagulopathy.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"339 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114422141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The possible Role of IFN-γ & TNF-α in bacterial eye infection patients IFN-γ和TNF-α在细菌性眼感染患者中的可能作用

Reviews and Research in Medical Microbiology Pub Date : 2023-01-11 DOI: 10.1097/MRM.0000000000000332

I. Abood, K. Rasool

引用次数: 0

Applications of nanotechnology in the fight against coronavirus disease 2019 纳米技术在抗击2019冠状病毒病中的应用

Reviews and Research in Medical Microbiology Pub Date : 2023-01-11 DOI: 10.1097/MRM.0000000000000335

R. Sayad, Huda Ahmed Abdelsabour, Samia Mohamed Farhat, Nehal Gamal Omer, Manar Magdy Ahmed, Ibrahim K.I. Elsayh, Islam H. Ibrahim, A. Algammal, Israa M. S. Al-Kadmy, G. Batiha, H. Hetta

{"title":"Applications of nanotechnology in the fight against coronavirus disease 2019","authors":"R. Sayad, Huda Ahmed Abdelsabour, Samia Mohamed Farhat, Nehal Gamal Omer, Manar Magdy Ahmed, Ibrahim K.I. Elsayh, Islam H. Ibrahim, A. Algammal, Israa M. S. Al-Kadmy, G. Batiha, H. Hetta","doi":"10.1097/MRM.0000000000000335","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000335","url":null,"abstract":"Background and aim: In early December 2019 started coronavirus disease 2019 (COVID-19) pandemic in China by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection which transmitted from bats to humans. According to WHO, there are more than two hundred million confirmed cases of COVID-19 including more than seven million deaths, so we desperately need to discover an effective treatment to eliminate SARS-CoV-2 infection permanently. One of the most promising technologies for the treatment of COVID-19 is Nanotechnology. Herein we tried to summarize usages of nanotechnology in fighting of COVID-19 and to focus on the challenges, advantages, and disadvantages of the application of this technology. Methods: Searching of PubMed, SCOPUS and Google scholar by using a specific search strategy “(COVID 19 OR COVID-19 Virus Disease OR COVID 19 Virus Infection OR 2019-nCoV Infection OR Coronavirus Disease-19 OR 2019 Novel Coronavirus Infection OR SARS-CoV-2 Infection OR COVID-19 Pandemic) AND nanotechnology. Results and Conclusions: Nanotechnology can be used in treatment, diagnosis and prevention of COVID-19. Many nanoparticle types can be used in treatment of COVID-19 such as polymers, dendrimers and quantum dots. In addition to these types of nanoparticles, there is Nan bot used for carrying out localized drug delivery and can be controlled by a user. We can also use quantum dots, metal and magnetic nanoparticles for the diagnosis of COVID-19 to increase the efficiency of diagnostic tests. Regarding to COVID-19 prevention, nanoparticles are used for the manufacture of nano-masks and vaccines such as: Oxford/AstraZeneca, Cansino, Moderna and Biotech/Pfizer vaccines. Each technology has advantages and disadvantages. Challenges remain in the domain for its application due to lack of knowledge.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131636401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Skin infections caused by Streptococcus pyogenes after the Eid Al-Adha 古尔邦节后由化脓性链球菌引起的皮肤感染

Reviews and Research in Medical Microbiology Pub Date : 2022-11-17 DOI: 10.1097/MRM.0000000000000330

Birol Safak, H. Albayrak, M. A. Kurç, Betül Günaydın

{"title":"Skin infections caused by Streptococcus pyogenes after the Eid Al-Adha","authors":"Birol Safak, H. Albayrak, M. A. Kurç, Betül Günaydın","doi":"10.1097/MRM.0000000000000330","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000330","url":null,"abstract":"Introduction: Streptococcus pyogenes is Gram-positive bacteria in chain form. Infections typically begin in the throat and skin, although they present with a many different clinical cases. This study aimed to present a different clinical manifestation related to S. pyogenes. Methods: In this study, swab samples were taken from patients who came to our center with skin lesions after Eid al-Adha. Identification was performed using conventional methods (bacitracin susceptibility test and PYR test) and VITEK 2 (bioMerieux, Marcy l’Etoile, France). Phylogenetic tree was generated using the Tamura Nei model of Neighbor-joining method in MEGA 6.0 program. Results: All of the isolated microorganisms were defined as S. pyogenes. Phylogenetic tree revealed that strains were highly related, but there were genetic differences between the strains. Conclusion: While Orf virus (Parapoxvirus) is the most common cause of skin lesions after Eid al-Adha, S. pyogenes was found to be the causative agent in our study. To our knowledge, cases of S. pyogenes skin infection due to religious practices have been reported for the first time.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133579321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emergence of extensively drug-resistant and colistin-resistant Klebsiella pneumoniae isolated from hospitalized patients in Isfahan, Iran 从伊朗伊斯法罕住院患者中分离出广泛耐药和耐粘菌素肺炎克雷伯菌

Reviews and Research in Medical Microbiology Pub Date : 2022-11-10 DOI: 10.1097/MRM.0000000000000324

J. Ghasemi, D. Shokri, S. M. Ghasemi

{"title":"Emergence of extensively drug-resistant and colistin-resistant Klebsiella pneumoniae isolated from hospitalized patients in Isfahan, Iran","authors":"J. Ghasemi, D. Shokri, S. M. Ghasemi","doi":"10.1097/MRM.0000000000000324","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000324","url":null,"abstract":"The current study was performed to investigate the antibiotic resistance pattern, the prevalence of colistin resistance and its molecular mechanisms in clinical isolates of Klebsiella pneumoniae obtained from hospitalized patients in teaching hospitals in Isfahan, Iran. This cross-sectional study was performed during 2019–2020 at several teaching hospitals in Isfahan, Iran. All the K. pneumoniae isolates were screened against 14 antimicrobial agents based on standard disk diffusion method. Moreover, the minimal inhibitory concentration (MIC) of colistin was determined by the E-test strips. Also, PCR assay was carried out to detect genes encoding resistance to colistin, including mcr-1, mcr-2, pmrA, pmrB, and crrB. In the present study, a total of 79 strains of multidrug-resistant K. pneumoniae were isolated. Of these, 35 colistin-resistant clinical K. pneumoniae isolates were obtained. Antibiotic susceptibility pattern showed a high rate of antibiotic resistance to ceftazidime (94.9%), while, the lowest resistance rate was observed against tigecycline (2.5%). All colistin-resistant isolates were classified as extensively drug-resistant (XDR). PCR results showed that mcr-1 and mcr-2 genes were not detected, while, 10.1% contained pmrA and pmrB genes. In addition, the frequency of crrB gene among our isolates was 3.8%. Due to the fact that the last line of treatment for infections associated with K. pneumoniae is colistin, increasing resistance to this antibiotic causes many concerns and problems in the treatment of patients. Detection of colistin-resistant strains and reporting of occurrence of genes associated with this resistance can greatly help in the treatment of diseases.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125851254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overview of heteroresistance, persistence and optimized strategies to control them 异源抗性、持久性及其优化控制策略综述

Reviews and Research in Medical Microbiology Pub Date : 2022-10-14 DOI: 10.1097/MRM.0000000000000325

M. Marjani, Haneen N. Mohammed, I. AL-Kadmy, Sarah N. Aziz

{"title":"Overview of heteroresistance, persistence and optimized strategies to control them","authors":"M. Marjani, Haneen N. Mohammed, I. AL-Kadmy, Sarah N. Aziz","doi":"10.1097/MRM.0000000000000325","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000325","url":null,"abstract":"Antibiotic-resistant bacteria have become much more prevalent, posing a significant concern to universal care. In basic concepts, the phenomenon of heteroresistance is typified as antibiotic resistance displayed by a subgroup of the entire bacterial community which is typically thought to be sensitive to these antibiotics based on standard in-vitro sensitivity assays. Although this small subgroup is temporarily dormant nondividing state displays enhanced resistance to broad antibiotics ranges. Persistence is a subpopulation of a sensitive bacterial isolate that can tolerate the bactericidal antibiotics because of its dormant physiological state. Until recent times, the occurrence of heteroresistance and persistence phenomena are often misunderstood and perhaps neglected. Here, we review the outline literature about bacterial heteroresistance, their detection methods, their associated mechanisms, the objectives of some bacterial species to develop heteroresistance. Bacterial persistence, some of their features, their main mechanisms, and their clinical importance are also described. Furthermore, this study provides optimized strategies to combat both phenomena.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134298883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The prevalence of phylogenetic group of Shiga toxin-producing Escherichia coli strain isolated from farm animals in Iran: a meta-analysis study 从伊朗农场动物中分离的产志贺毒素大肠杆菌菌株系统发育群的流行:一项荟萃分析研究

Reviews and Research in Medical Microbiology Pub Date : 2022-09-21 DOI: 10.1097/MRM.0000000000000327

Forogh Mohammadi, H. Sedigh Ebrahim-Saraie, Neda Sinaei, M. Karimi-Dehkordi

{"title":"The prevalence of phylogenetic group of Shiga toxin-producing Escherichia coli strain isolated from farm animals in Iran: a meta-analysis study","authors":"Forogh Mohammadi, H. Sedigh Ebrahim-Saraie, Neda Sinaei, M. Karimi-Dehkordi","doi":"10.1097/MRM.0000000000000327","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000327","url":null,"abstract":"Background: The study of the prevalence of the phylogenetic group in the Shiga toxin-producing Escherichia coli (STEC) strain isolated from farm animals is valuable for epidemiology aspects; therefore, the current systematic review and meta-analysis aimed to investigate the prevalence of the phylogenetic group in STEC isolates obtained from farm animals in Iran. Methods: A systematic literature search was conducted in the Web of Science, PubMed, Scopus, and Embase electronic databases. The search investigated articles published by Iranian authors to the end of December 2020. Analysis of data was conducted using the Comprehensive Meta-Analysis Software (Biostat Company). To estimate the pooled prevalence and the corresponding 95% confidence interval (CI), the random-effects model was used. Results: Our comprehensive search identified nine studies with eligibility criteria subjected to the meta-analysis. The pooled prevalence of phylogroup A was 21% (95% CI: 10–38). There was significant heterogeneity among the nine studies (χ2 = 92.52; P < 0.001; I2 = 91.35%). Additionally, the pooled prevalence of phylogroups B1, B2 and D among the nine studies was 63, 3, and 9%, respectively. The subgroup analysis results based on healthy and diarrheic cases indicated that the rate of phylogroup A in healthy and diarrheic samples was 27 and 2%, respectively. For phylogroup B1, this rate was 55 and 88% in healthy and diarrheic samples, respectively. Conclusion: In summary, our results demonstrated that domestic animals might be the possible reservoirs of STEC in the studied population. Comparison of the phylogroup characteristics of the STEC strain obtained from different sources exhibited a partial genetic diversity in isolates, and there was heterogeneity among the studies in terms of phylogenetic groups. This study provides important information about STEC regarding the phylogenetic characteristics","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134050364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe acute respiratory syndrome coronavirus 2 pandemic and older people: what we know about the clinical, laboratory, imaging features, and clinical outcomes 严重急性呼吸综合征冠状病毒大流行与老年人:我们对临床、实验室、影像学特征和临床结果的了解

Reviews and Research in Medical Microbiology Pub Date : 2022-09-21 DOI: 10.1097/MRM.0000000000000329

Shereen Abdel Alem, A. Moustafa

{"title":"Severe acute respiratory syndrome coronavirus 2 pandemic and older people: what we know about the clinical, laboratory, imaging features, and clinical outcomes","authors":"Shereen Abdel Alem, A. Moustafa","doi":"10.1097/MRM.0000000000000329","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000329","url":null,"abstract":"The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an emerging and rapidly evolving situation. Older people represent a uniquely vulnerable group during any infectious disease outbreaks due to their altered physiology, increased susceptibility to infections, presence of comorbidities, malnutrition, and compromised immunological and mechanical functions. The clinical symptoms, laboratory, and imaging features of SARS-CoV-2 are similar to younger adults but rapid disease progression, a high proportion of severe to critical cases, and a high fatality rate are more observed in the older people. To date, no targeted therapy is available for SARS-CoV-2, many drugs are still being tested for efficacy and safety due to the novelty of the virus and little knowledge about it among the older people. In this article, we summarize the clinical, laboratory, radiological features, and clinical outcomes of SARS-CoV-2 infection in the older people and present the predictive factors associated with fatal clinical outcomes among them.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121170806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of genes involved in the binding and invasion of Klebsiella pneumoniae including fimH-1, entB, iutA, rmpA and cnf-1 genes in patients with urinary tract infection 尿路感染患者与肺炎克雷伯菌结合和侵袭相关基因(包括fimH-1、entB、iutA、rmpA和cnf-1)的评估

Reviews and Research in Medical Microbiology Pub Date : 2022-09-21 DOI: 10.1097/MRM.0000000000000322

Bahman Yousefi, A. Abdolshahi, M. Dadashpour, Daryoush Pahlevan, H. Ghaffari, M. Eslami

{"title":"Evaluation of genes involved in the binding and invasion of Klebsiella pneumoniae including fimH-1, entB, iutA, rmpA and cnf-1 genes in patients with urinary tract infection","authors":"Bahman Yousefi, A. Abdolshahi, M. Dadashpour, Daryoush Pahlevan, H. Ghaffari, M. Eslami","doi":"10.1097/MRM.0000000000000322","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000322","url":null,"abstract":"Introduction: Klebsiella pneumoniae is a member of the Enterobacteriaceae that causes nosocomial infections. The aim of this study was to identify the binding, invasive and pathogenic profiles of K. pneumoniae isolates in urinary tract infection. Materials and methods: This study was performed with 70 isolates. The antibiotic susceptibility testing was conducted by 12 antibiotics. The presence of virulence genes (fimH-1, mrkD, kpn, ycfM, entB, iutA, irp-1, irp-2, ybtS, fyuA, iroN, rmpA, magA, traT, hlyA and cnf-1) done by PCR. Results: The strains resistant to imipenem, also resistant to the cefotaxime/ceftazidime and azteronam. 96.4% of rmpA strains also had entB and 92.8% had ycfM gene. Of the 12 strains containing cnf1, all also had fimH and the mrkD gene. These strains had a high resistance the amoxicillin, tobramycin, ciprofloxacin and gentamicin. Strains containing the hlyA all had fimH and were high resistant to the amoxicillin/clavulanic acid, amikacin, and tobramycin. magA-containing strains had low resistance to amikacin and azteronam. Conclusion: It is recommended that imipenem resistant strains be resistant to cefotaxime, ceftazidime, and aztereonam, and that these antibiotics not be used to treat these strains. Interestingly, strains with the cnf-1 were all sensitive to imipenem, so imipenem is a good option for treating these strains. Strains that had the hlyA all had the fimH gene and had a very high resistance to the amoxicillin/clavulanic acid, amikacin and tobramycin. magA-containing strains all had entB and had low resistance to amikacin and aztereonam. Therefore, amikacin and aztereonam are recommended for the treatment of these strains containing.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"8 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120896395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative and qualitative profile of aerobic bacteria in the second mandibular molar free of caries and caries, based on a case–control study 基于病例对照研究的下颌第二磨牙无龋和龋齿需氧细菌的定量和定性分析

Reviews and Research in Medical Microbiology Pub Date : 2022-09-21 DOI: 10.1097/MRM.0000000000000326

A. Al-Janabi

{"title":"Quantitative and qualitative profile of aerobic bacteria in the second mandibular molar free of caries and caries, based on a case–control study","authors":"A. Al-Janabi","doi":"10.1097/MRM.0000000000000326","DOIUrl":"https://doi.org/10.1097/MRM.0000000000000326","url":null,"abstract":"Bacteria growing in the oral cavity are an important effective factor in causing caries. Molars are the most commonly affected by bacterial decay. Bacterial species and their counts in caries of the second mandibular molar compared with those in caries-free teeth were investigated. A total of 100 patients with caries in the second mandibular molar and 95 caries-free individuals participated in a case–control study. A swab from the molar zone was cultured to identify the bacterial species. Colony counts and the frequency with which isolated bacteria occur were also determined. The isolated bacteria comprised 34 species ranging between 22 Gram-positive and 12 Gram-negative bacteria from caries molar and 14 species from the control group were diagnosed. Staphylococcus aureus and Kocuria rosea were revealed to have a more significant frequency in caries patients, whereas Kocuria kristinae was isolated with a high frequency from caries-free individuals. The majority of isolates had a large number of colonies, mostly Gram-positive bacteria. Some species have been found in one group of participants but not in another. Six bacterial species were only isolated from control group, whereas the patient group had 16 species that were not found in the control group. In conclusion, Gram-positive bacteria are most frequently associated with caries on the second mandibular molar. Some species of Gram-positive bacteria such as S. aureus and K. rosea and Gram-negative bacteria such as Pseudomonas fluorescens and Escherichia coli occur with great diversity and quantity with caries of the second mandibular molar compared with that of healthy individuals. Meanwhile, some species may disappear or be limited to the decayed area of the second mandibular molar.","PeriodicalId":231643,"journal":{"name":"Reviews and Research in Medical Microbiology","volume":"224 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127191459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0