{"title":"Physiologic and Pathophysiologic Functions of Purinoceptors in Voiding Reflex.","authors":"D. Kim","doi":"10.5213/JKCS.2008.12.2.93","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.93","url":null,"abstract":"Purinergic neurotransmission has been regarded as major component of non-adrenergic, noncholinergic (NANC) contraction in detrusor smooth muscle. Although in normal human detrusor, this contraction seems to be small, the importance of the NANC component for detrusor contraction in disease conditions such as detrusor overactivity remains to be established. Based on many evidences for purinergic contributions in lower urinary tract, ATP and purinoceptors has been suggested to be involved in both efferent and afferent mechanism in voiding reflex. ATP signaling via P2X1 receptors plays an important role in efferent neural control of urinary bladder function, although to varying degrees across species from experimental animals to men. The efferent function of purinoceptors may be enhanced in detrusor overactivity and aging. ATP also suggested being involved in mechanosensory transmission, via activation of P2X3 and P2X2/3 receptors on sensory afferent nerves. The afferent function of purinoceptors may be related with pathophysiology of overactive bladder or interstitial cystitis, mediating bladder hyperexicitability. These results suggest that the selective antagonists for the purinoceptors may offer better relief of sensory and motor symptoms for overactive bladder or interstitial cystitis patients in the future. (J Korean Continence Soc 2008;12:93-8)","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"387 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122844748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Propiverine for Chronic Prostatitis / Chronic Pelvic Pain Syndrome","authors":"Hyung Jee Kim, J. Hong","doi":"10.5213/JKCS.2008.12.2.158","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.158","url":null,"abstract":"Hypothesis / aims of study Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder to men and the syndrome is diagnosed only on the basis of symptoms, principally pain or discomfort in the pelvic region. However many patients have a urinary symptoms, especially storage symptoms such as frequency and urgency. The aim of this study was to evaluate the efficacy of anticholinergics in a prospective randomized, single-blind trial to young and middle aged patients to exclude the effect of benign prostatic hyperplasia as possible. Study design, materials and methods Forty six men with CP/CPPS (age of third to fifth decades) were randomized in a single-blind fashion to receive either group 1; antibiotics of 15 patients, or group 2; antibiotics and propiverine (20mg, once daily) of 31 patients for 2 months. The NIH chronic prostatitis symptom index (NIH-CPSI) and International Prostate Symptom Score (IPSS) were used to grade symptoms and the quality of life (QoL) impact at the start, 1 month and 2 months of the study. Results There was no significant difference between group 1 and group 2 in about age and duration of the disease. In addition, no significant difference was found between group 1 and 2 in the scores of sub-factors of IPSS and NIH-CPSI at the time of baseline. No statistically significant difference in the NIH-CPSI total score and each domain was seen after treatment. Statistically significant difference in the storage symptom of IPSS was seen after treatment. Interpretation of results Only storage symptoms in CP/CPPS were responded to propiverine treatment, but not pain.","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114506511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Chung, Y. Kim, J. Park, S. H. Park, Young Soo Kim, J. Choi
{"title":"Spontaneous Perinephric Urinoma in a Patient with Neurogenic Bladder.","authors":"Y. Chung, Y. Kim, J. Park, S. H. Park, Young Soo Kim, J. Choi","doi":"10.5213/JKCS.2008.12.2.185","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.185","url":null,"abstract":"Spontaneous rupture of the renal pelvis or ureteropelvic juction area with extravasation of urine into the perinephric space is an uncommon pathologic condition (1). We report a case of 72-year -old woman who suffered 2 days of left loin pain. The patient has got residual urine sensation and weak urine stream since she has gone through a radical hysterectomy 17 years before. Because of these symptoms of voiding difficulty, the patient had abdominal straining during her urination. A CT scan exhibited renal pelvis rupture with perirenal extravasation of urine due to severe hydronephrosis, that was exacerbated by hidden neurogenic bladder disease. Moreover, the patient has detrusor underactivity and high intravesical pressure at voiding trial in the urodynamic study. One month after the percutaneous nephrostomy insertion into the left renal pelvis, the patient was successfully treated. The size of renal pelvis decreased. Moreover, urinoma disappeared in follow up CT scan image. (J Korean Continence Soc 2008;12:185-8)","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128376577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Lower Urinary Tract Symptoms Associated with Prostate Findings in Occupational Taxi Drivers and Office Workers in Uijeongbu, Korea","authors":"Y. Lee, Dong Sup Lee, S. Kang, C. Han","doi":"10.5213/JKCS.2008.12.2.127","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.127","url":null,"abstract":"Puropose: To analyze lower urinary tract symptoms associated with prostate findings in occupational taxi drivers compared to office workers in Uijeongbu, Korea. Material and methods: A population-based cross-sectional survey was conducted among drivers and office workers in Uijeongbu, Korea. All participants filled out the International Prostate Symptom Score (IPSS) questionnaire and the age, career, height and body weight were also recorded. They had uroflowmetry (UFM), transrectal ultrasound (TRUS) and prostatic cancer screening testing (PSA). We evaluated the parameters and compared them between the two groups. Results: There was no significant difference in age, career and BMI between the two groups (p<0.01). For each group, the IPSS was closely related to the maximal flow rate (Qmax) (p<0.01). The mean value of the IPSS was 13.53±7.70 in the taxi drivers and 9.71±5.72 in office workers; therefore, the IPSSs showed a difference between the two groups (p=0.041). However, there were no significant differences among the other parameters between two groups. The value of Qmax was not significantly different in the comparisons between the two groups (p=0.973). Conclusions: Although the IPSS in taxi drivers was higher than in office workers, the objective parameters studied were not significantly different between the two groups. Therefore, there was no clinical evidence of higher morbidity associated with prostate abnormalities in taxi drivers compared to office workers. (J Korean Continence Soc 2008;12:127-32)","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132779092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Choi, Sun Ouck Kim, D. Kwon, Kwangsung Park, S. Ryu
{"title":"The Effect of Nocturia on Health-related Quality of Life and Medical Outcomes Study Sleep Score in Female.","authors":"H. Choi, Sun Ouck Kim, D. Kwon, Kwangsung Park, S. Ryu","doi":"10.5213/JKCS.2008.12.2.178","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.178","url":null,"abstract":"Puropose: To evaluate the effects of nocturia on health-related quality of life (HRQoL) and sleep. Material and methods: From January 2007 to December 2007, 180 patients with lower urinary tract symptoms were prospectively selected for this study. Study was conducted among respondents with nocturia (void/night≥1) (n=119) and age matched controls (no nocturia) (n=61), with participants completing a series of questionnaires on HRQoL (OAB-q short form) and Medical Outcomes Study (MOS) sleep scale and frequency voiding chart. Results: The patients population had a mean age of 57.2 years. In the patients, the mean number of void per night was measured, 58 patients reported 2>void/night≥1, 32 patients reported 3> voids/night≥2 and 29 patients reported void/night≥3. The number of nocturia episodes/night was significantly associated with the overactive bladder (OAB) symptom score (p=0.001), symptom bother (p=0.001) and the MOS sleep index (p=0.016). Conclusions: Increases in the number of voids/night have further negative effects on sleep, symptom bother and HRQoL. (J Korean Continence Soc 2008;12:178-84)","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115165915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Kim, Wonjin Cho, J. Huh, J. Seo, S. Yang, Kyu-Sung Lee, Ju Hwan Lee, M. Choo, Ha Young Kim, Chul Hee Park, Joon Chul Kim
{"title":"Efficacy and Safety of Propiverine Hydrochloride 40mg in Treatment of Overactive Bladder : Prospective, Multicenter, Observational study.","authors":"S. Kim, Wonjin Cho, J. Huh, J. Seo, S. Yang, Kyu-Sung Lee, Ju Hwan Lee, M. Choo, Ha Young Kim, Chul Hee Park, Joon Chul Kim","doi":"10.5213/JKCS.2008.12.2.114","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.114","url":null,"abstract":"From the Department of Urology, The catholic University of Korea College of Medicine, Dong-A University College of Medicine, Cheju University School of Medicine, Kwandong University College of Medicine, Konkuk University College of Medicine, Sungkyunkwan University School of Medicine, Daegu Fatima Hospital, University of Ulsan College of Medicine, School of Medicine Hallym University, Keimyung University School of Medicine","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114917188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seo Yeon Lee, M. S. Ha, Tae Heung Kim, Hyung Oh Shin, S. Lee, Tae Hyoung Kim
{"title":"Comparison of the Short Term Results of Monarc and TVT-O Transobturator-tape Procedures for the Treatment of Stress Urinary Incontinence.","authors":"Seo Yeon Lee, M. S. Ha, Tae Heung Kim, Hyung Oh Shin, S. Lee, Tae Hyoung Kim","doi":"10.5213/JKCS.2008.12.2.163","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.163","url":null,"abstract":"Puropose: Transobturator sling is a new minimally invasive treatment for female stress urinary incontinence. We compared the efficacy and safety of the two procedures, Monarc and TVT-O. Material and methods: We included 110 patients with stress urinary incontinence who underwent the Monarc (n=52) or TVT-O (n=58) procedure and followed up at least for 1 year. Preoperative evaluations, the indices of voiding and postoperative complication were investigated. They were analyzed by Student's t-test, Paired t-test and chi-square test. Results: There were no significant difference in the preoperative patients' characteristics, postoperative complication and success rate between the two groups. The preoperative and postoperative storage symptoms between two groups had no significant difference but the patients of both groups had significant improvement in storage symptoms such as frequency and urgency after surgery. Conclusions: The Monarc and TVT-O is equally effective and safe procedures as a treatment method of female stress urinary incontinence. (J Korean Continence Soc 2008;12:163-8)","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129792889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcomes of the Transobturator Tape Procedure for Elderly Women above 60 Years Old with Stress Urinary Incontinence.","authors":"D. G. Shin, T. K. Jeon, Jeong Zoo Lee","doi":"10.5213/JKCS.2008.12.2.139","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.2.139","url":null,"abstract":"Puropose: This study was aimed at evaluating the clinical efficacy, satisfaction and complication of patients with transobturator tape (TOT) operation for the elderly women suffering with stress urinary incontinence (SUI). Material and methods: 58 women with stress urinary incontinence who underwent TOT procedure between March 2004 and June 2006 were included in this study. To assess whether outcome was influenced by the patient's age, the patients were divided into two age groups: women aged 60 years and older (n=22) and women aged less than 60 years (n=36). Preoperatively, the patients were evaluated with history taking, a physical examination, a one-hour pad test, uroflowmetry and urodynamic study. The procedure was carried out using a previously established method under local anesthesia. The post-operative symptoms and patient satisfaction were assessed by questionnaire. Results: There was no significant difference between the 2 groups in terms of the success rate: cure (71.4% vs. 78.2%, p=0.746), improved (19.1% vs. 9.3%, p=0.415), and same as preoperation (9.5% vs. 12.5%, p=1.000) for above 60 years old women and less than 60 years old women, respectively. In addition, the patient satisfaction rate was not different significantly between 2 groups. De novo urge symptoms were observed in 2 women aged 60 years and older. The intraoperative complications were not found. Conclusions: TOT procedure in elderly women with SUI offers high success rate and satisfaction for operation. TOT should play a significant role in treating them, due to its safety and availability. However, we do not know how long the improvement of voiding symptoms will last, and so additional longer term follow-up should be done. (J Korean Continence Soc 2008;12:139-44)","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129324922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proteomic Analysis of Proteins changed by Bilateral Orchiectomy in the Male Rabbit Bladder.","authors":"Hyung Jee Kim, J. Hong","doi":"10.5213/jkcs.2008.12.2.121","DOIUrl":"https://doi.org/10.5213/jkcs.2008.12.2.121","url":null,"abstract":"Study design, materials and methods New Zealand white male rabbits (2.5-3 kg) were divided into 2 group; control group with 5 rabbits and bilateral orchiectomized group, bilateral orchiectomized group was divided into post-operative 4 weeks group (group 1), and 8 weeks group (group 2) with 5 rabbits respectively. Bladder wall was excised partly at 4 or 8 weeks from the beginning of the experiment. Conventional proteomics was performed with high resolution 2-D gel electrophoresis followed by computational image analysis and protein identification using mass spectrometry. We decided to consider ‘significant’ if protein had 50% decreasing or 200% increasing expression rate.","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130674401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyu-Sung Lee, D. Han, J. Kim, Jin Woo Chung, S. Choo, Joon Chul Kim, J. Seo, M. Choo
{"title":"Efficacy and Safety of Doxazosin GITS over 4 weeks for the Treatment of Non-neurogenic Voiding Dysfunction in Females: Short-term Outcomes.","authors":"Kyu-Sung Lee, D. Han, J. Kim, Jin Woo Chung, S. Choo, Joon Chul Kim, J. Seo, M. Choo","doi":"10.5213/JKCS.2008.12.1.19","DOIUrl":"https://doi.org/10.5213/JKCS.2008.12.1.19","url":null,"abstract":"","PeriodicalId":231333,"journal":{"name":"Journal of the Korean Continence Society","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126636019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}